7 research outputs found

    Working Memory : Celebration, Succession Planning, and Lessons Learned in Florida\u27s Archival Institutions

    No full text
    Presentation delivered in a panel session at the annual meeting of the Society of Florida Archivists, held on Thursday, 14 May 2015, at the Courtyard by Marriott--Miami, in Coconut Grove

    Review: Glycation of human serum albumin

    Get PDF
    Glycation involves the non-enzymatic addition of reducing sugars and/or their reactive degradation products to amine groups on proteins. This process is promoted by the presence of elevated blood glucose concentrations in diabetes and occurs with various proteins that include human serum albumin (HSA). This review examines work that has been conducted in the study and analysis of glycated HSA. The general structure and properties of HSA are discussed, along with the reactions that can lead to modification of this protein during glycation. The use of glycated HSA as a short-to-intermediate term marker for glycemic control in diabetes is examined, and approaches that have been utilized for measuring glycated HSA are summarized. Structural studies of glycated HSA are reviewed, as acquired for both in vivo and in vitro glycated HSA, along with data that have been obtained on the rate and thermodynamics of HSA glycation. In addition, this review considers various studies that have investigated the effects of glycation on the binding of HSA with drugs, fatty acids and other solutes and the potential clinical significance of these effects

    ManyBabies 5: A large-scale investigation of the proposed shift from familiarity preference to novelty preference in infant looking time Pre-data collection manuscript for peer-review The ManyBabies 5 Team

    No full text
    International audienceMuch of our basic understanding of cognitive and social processes in infancy relies on measures of looking time, and specifically on infants' visual preference for a novel or familiar stimulus. However, despite being the foundation of many behavioral tasks in infant research, the determinants of infants' visual preferences are poorly understood, and differences in the expression of preferences can be difficult to interpret. In this large-scale study, we test predictions from the Hunter and Ames model of infants' visual preferences. 1 We investigate the effects of three factors predicted by this model to determine infants' preference for novel versus familiar stimuli: age, stimulus familiarity, and stimulus complexity. Drawing from a large and diverse sample of infant participants (N = XX), this study will provide crucial empirical evidence for a robust and generalizable model of infant visual preferences, leading to a more solid theoretical foundation for understanding the mechanisms that underlie infants' responses in common behavioral paradigms. Moreover, our findings will guide future studies that rely on infants' visual preferences to measure cognitive and social processes

    ManyBabies 5: A large-scale investigation of the proposed shift from familiarity preference to novelty preference in infant looking time

    No full text
    Much of our basic understanding of cognitive and social processes in infancy relies on measures of looking time, and specifically on infants’ visual preference for a novel or familiar stimulus. However, despite being the foundation of many behavioral tasks in infant research, the determinants of infants’ visual preferences are poorly understood, and differences in the expression of preferences can be difficult to interpret. In this large-scale study, we test predictions from the Hunter and Ames model of infants' visual preferences. We investigate the effects of three factors predicted by this model to determine infants’ preference for novel versus familiar stimuli: age, stimulus familiarity, and stimulus complexity. Drawing from a large and diverse sample of infant participants (minimum expected sample size N = 1,280), this study aims to provide empirical evidence for a robust and generalizable model of infant visual preferences, leading to a more solid theoretical foundation for understanding the mechanisms that underlie infants’ responses in common behavioral paradigms. Moreover, we hope that our findings will guide future studies that rely on infants' visual preferences to measure cognitive and social processes

    ManyBabies 5: A large-scale investigation of the proposed shift from familiarity preference to novelty preference in infant looking time [ Registered Report Stage 1 Protocol]”

    No full text
    ABSTRACT Much of our basic understanding of cognitive and social processes in infancy relies on measures of looking time, and specifically on infants’ visual preference for a novel or familiar stimulus. However, despite being the foundation of many behavioral tasks in infant research, the determinants of infants’ visual preferences are poorly understood, and differences in the expression of preferences can be difficult to interpret. In this large-scale study, we test predictions from the Hunter and Ames model of infants' visual preferences. We investigate the effects of three factors predicted by this model to determine infants’ preference for novel versus familiar stimuli: age, stimulus familiarity, and stimulus complexity. Drawing from a large and diverse sample of infant participants (minimum expected sample size N = 1,280), this study aims to provide empirical evidence for a robust and generalizable model of infant visual preferences, leading to a more solid theoretical foundation for understanding the mechanisms that underlie infants’ responses in common behavioral paradigms. Moreover, we hope that our findings will guide future studies that rely on infants' visual preferences to measure cognitive and social processes. ITEMS Stage 1 Registered Report Protocol, Stage 1 Registered Report Supplementary Material,  Stage 1 Registered    Data Simulation and Power Analysis SupplementReport  </p
    corecore