Adiabatic Approximation for weakly open systems

We generalize the adiabatic approximation to the case of open quantum systems, in the joint limit of slow change and weak open system disturbances. We show that the approximation is ``physically reasonable'' as under wide conditions it leads to a completely positive evolution, if the original master equation can be written on a time-dependent Lindblad form. We demonstrate the approximation for a non-Abelian holonomic implementation of the Hadamard gate, disturbed by a decoherence process. We compare the resulting approximate evolution with numerical simulations of the exact equation.Comment: New material added, references added and updated, journal reference adde

Holonomy for Quantum Channels

A quantum holonomy reflects the curvature of some underlying structure of quantum mechanical systems, such as that associated with quantum states. Here, we extend the notion of holonomy to families of quantum channels, i.e., trace preserving completely positive maps. By the use of the Jamio{\l}kowski isomorphism, we show that the proposed channel holonomy is related to the Uhlmann holonomy. The general theory is illustrated for specific examples. We put forward a physical realization of the channel holonomy in terms of interferometry. This enables us to identify a gauge invariant physical object that directly relates to the channel holonomy. Parallel transport condition and concomitant gauge structure are delineated in the case of smoothly parametrized families of channels. Finally, we point out that interferometer tests that have been carried out in the past to confirm the $4\pi$ rotation symmetry of the neutron spin, can be viewed as early experimental realizations of the channel holonomy.Comment: Minor changes, journal reference adde

An Upper Mass Limit on a Red Supergiant Progenitor for the Type II-Plateau Supernova SN 2006my

We analyze two pre-supernova (SN) and three post-SN high-resolution images of the site of the Type II-Plateau supernova SN 2006my in an effort to either detect the progenitor star or to constrain its properties. Following image registration, we find that an isolated stellar object is not detected at the location of SN 2006my in either of the two pre-SN images. In the first, an I-band image obtained with the Wide-Field and Planetary Camera 2 on board the Hubble Space Telescope, the offset between the SN 2006my location and a detected source ("Source 1") is too large: > 0.08", which corresponds to a confidence level of non-association of 96% from our most liberal estimates of the transformation and measurement uncertainties. In the second, a similarly obtained V-band image, a source is detected ("Source 2") that has overlap with the SN 2006my location but is definitively an extended object. Through artificial star tests carried out on the precise location of SN 2006my in the images, we derive a 3-sigma upper bound on the luminosity of a red supergiant that could have remained undetected in our pre-SN images of log L/L_Sun = 5.10, which translates to an upper bound on such a star's initial mass of 15 M_Sun from the STARS stellar evolutionary models. Although considered unlikely, we can not rule out the possibility that part of the light comprising Source 1, which exhibits a slight extension relative to other point sources in the image, or part of the light contributing to the extended Source 2, may be due to the progenitor of SN 2006my. Only additional, high-resolution observations of the site taken after SN 2006my has faded beyond detection can confirm or reject these possibilities.Comment: Minor text changes from Version 1. Appendix added detailing the determination of confidence level of non-association of point sources in two registered astronomical image

CFT and Entropy on the Brane

We consider a brane-universe in the background of an Anti-de Sitter/ Schwarschild geometry. We show that the induced geometry of the brane is exactly given by that of a standard radiation dominated FRW-universe. The radiation is represented by a strongly coupled CFT with an AdS-dual description. We show that when the brane crosses the horizon of the AdS-black hole the entropy and temperature are simply expressed in the Hubble constant and its time derivative. We present formulas for the entropy of the CFT which are generally valid, and which at the horizon coincide with the FRW equations. These results shed new light on recently proposed entropy bounds in the context of cosmology.Comment: 10 pages, 2 figures, axodraw; v2: minor corrections and references added; v3: reference added, published versio

A full gap above the Fermi level: the charge density wave of monolayer VS2

In the standard model of charge density wave (CDW) transitions, the displacement along a single phonon mode lowers the total electronic energy by creating a gap at the Fermi level, making the CDW a metal–insulator transition. Here, using scanning tunneling microscopy and spectroscopy and ab initio calculations, we show that VS2 realizes a CDW which stands out of this standard model. There is a full CDW gap residing in the unoccupied states of monolayer VS2. At the Fermi level, the CDW induces a topological metal-metal (Lifshitz) transition. Non-linear coupling of transverse and longitudinal phonons is essential for the formation of the CDW and the full gap above the Fermi level. Additionally, x-ray magnetic circular dichroism reveals the absence of net magnetization in this phase, pointing to coexisting charge and spin density waves in the ground state

Digital Health Transformation of Integrated Care in Europe: Overarching Analysis of 17 Integrated Care Programs

Background: Digital health tools comprise a wide range of technologies to support health processes. The potential of these technologies to effectively support health care transformation is widely accepted. However, wide scale implementation is uneven among countries and regions. Identification of common factors facilitating and hampering the implementation process may be useful for future policy recommendations. Objective: The aim of this study was to analyze the implementation of digital health tools to support health care and social care services, as well as to facilitate the longitudinal assessment of these services, in 17 selected integrated chronic care (ICC) programs from 8 European countries. Methods: A program analysis based on thick descriptions including document examinations and semistructured interviews with relevant stakeholders of ICC programs in Austria, Croatia, Germany, Hungary, the Netherlands, Norway, Spain, and the United Kingdom was performed. A total of 233 stakeholders (ie, professionals, providers, patients, carers, and policymakers) were interviewed from November 2014 to September 2016. The overarching analysis focused on the use of digital health tools and program assessment strategies. Results: Supporting digital health tools are implemented in all countries, but different levels of maturity were observed among the programs. Only few ICC programs have well-established strategies for a comprehensive longitudinal assessment. There is a strong relationship between maturity of digital health and proper evaluation strategies of integrated care. Conclusions: Notwithstanding the heterogeneity of the results across countries, most programs aim to evolve toward a digital transformation of integrated care, including implementation of comprehensive assessment strategies. It is widely accepted that the evolution of digital health tools alongside clear policies toward their adoption will facilitate regional uptake and scale-up of services with embedded digital health tools

Dying Dyons Don't Count

The dyonic 1/4-BPS states in 4D string theory with N=4 spacetime supersymmetry are counted by a Siegel modular form. The pole structure of the modular form leads to a contour dependence in the counting formula obscuring its duality invariance. We exhibit the relation between this ambiguity and the (dis-)appearance of bound states of 1/2-BPS configurations. Using this insight we propose a precise moduli-dependent contour prescription for the counting formula. We then show that the degeneracies are duality-invariant and are correctly adjusted at the walls of marginal stability to account for the (dis-)appearance of the two-centered bound states. Especially, for large black holes none of these bound states exists at the attractor point and none of these ambiguous poles contributes to the counting formula. Using this fact we also propose a second, moduli-independent contour which counts the "immortal dyons" that are stable everywhere.Comment: 27 pages, 2 figures; one minus sign correcte

Swarm accelerometer data processing from raw accelerations to thermospheric neutral densities

The Swarm satellites were launched on November 22, 2013, and carry accelerometers and GPS receivers as part of their scientific payload. The GPS receivers do not only provide the position and time for the magnetic field measurements, but are also used for determining non-gravitational forces like drag and radiation pressure acting on the spacecraft. The accelerometers measure these forces directly, at much finer resolution than the GPS receivers, from which thermospheric neutral densities can be derived. Unfortunately, the acceleration measurements suffer from a variety of disturbances, the most prominent being slow temperature-induced bias variations and sudden bias changes. In this paper, we describe the new, improved four-stage processing that is applied for transforming the disturbed acceleration measurements into scientifically valuable thermospheric neutral densities. In the first stage, the sudden bias changes in the acceleration measurements are manually removed using a dedicated software tool. The second stage is the calibration of the accelerometer measurements against the non-gravitational accelerations derived from the GPS receiver, which includes the correction for the slow temperature-induced bias variations. The identification of validity periods for calibration and correction parameters is part of the second stage. In the third stage, the calibrated and corrected accelerations are merged with the non-gravitational accelerations derived from the observations of the GPS receiver by a weighted average in the spectral domain, where the weights depend on the frequency. The fourth stage consists of transforming the corrected and calibrated accelerations into thermospheric neutral densities. We present the first results of the processing of Swarm C acceleration measurements from June 2014 to May 2015. We started with Swarm C because its acceleration measurements contain much less disturbances than those of Swarm A and have a higher signal-to-noise ratio than those of Swarm B. The latter is caused by the higher altitude of Swarm B as well as larger noise in the acceleration measurements of Swarm B. We show the results of each processing stage, highlight the difficulties encountered, and comment on the quality of the thermospheric neutral density data set.Astrodynamics & Space Mission

A boundary stress tensor for higher-derivative gravity in AdS and Lifshitz backgrounds

We investigate the Brown-York stress tensor for curvature-squared theories. This requires a generalized Gibbons-Hawking term in order to establish a well-posed variational principle, which is achieved in a universal way by reducing the number of derivatives through the introduction of an auxiliary tensor field. We examine the boundary stress tensor thus defined for the special case of `massive gravity' in three dimensions, which augments the Einstein-Hilbert term by a particular curvature-squared term. It is shown that one obtains finite results for physical parameters on AdS upon adding a `boundary cosmological constant' as a counterterm, which vanishes at the so-called chiral point. We derive known and new results, like the value of the central charges or the mass of black hole solutions, thereby confirming our prescription for the computation of the stress tensor. Finally, we inspect recently constructed Lifshitz vacua and a new black hole solution that is asymptotically Lifshitz, and we propose a novel and covariant counterterm for this case.Comment: 25 pages, 1 figure; v2: minor corrections, references added, to appear in JHE

Randomized implementation of a primary human papillomavirus testing-based cervical cancer screening protocol for women 34 to 69 years in Norway

Background: Cervical cancer screening programs are facing a programmatic shift where screening protocol based on human papillomavirus testing (HPV-Screening protocol) is replacing the liquid-based cytology (LBC-Screening protocol). For safe technology transfer within the nationwide screening programme in Norway, HPV-Screening protocol was implemented randomized to compare the real-world effectiveness of HPV-Screening protocol and LBC-Screening protocol at the first screening round. Methods: Among 302,295 women ages 34 to 69 years scheduled to attend screening from February 2015 to June 2017, 157,447 attended. A total of 77,207 were randomly allocated to the HPV-Screening protocol and 80,240 were allocated to the LBC-Screening protocol. All women were followed up for 18 months. Results: The HPV-Screening protocol resulted in a relative increase of 60% in the detection of cervical intraepithelial neoplasia (CIN) grade 2 or worse [risk ratio (RR) = 1.6, 95% confidence interval (CI) = 1.5–1.7], 40% in CIN grade 3 or worse (RR = 1.4, 95% CI = 1.3–1.6), 40% in cancer (RR = 1.4, 95% CI = 1.0–2.1), and 60% in colposcopy referrals (RR = 1.6, 95% CI = 1.5–1.6) compared with LBC-Screening. The performance of both protocols was age dependent, being more effective in women ages under 50 years. Conclusions: The HPV-Screening protocol was well accepted by women in Norway and detected more CIN2, CIN3, and cancers compared with the LBC-Screening protocol. Impact: A randomized implementation of the HPV-Screening protocol with real-world assessment enabled a gradual, quality assured, and safe technology transition. HPV-based screening protocol may further be improved by using HPV genotyping and age-specific referral algorithms.publishedVersio