Relationship between serum soluble endothelial protein C receptor level and COVID-19 findings

Coronavirus-related disease-2019 (COVID-19)-associated coagulopathy presents predominantly with thrombosis and leads to complications in close association with inflammatory process. Soluble endothelial protein C receptor (sEPCR), which is the soluble form of EPCR, reduces the anticoagulant and anti-inflammatory activity of activated protein C. The purpose of this study is to investigate the relationship between sEPCR and the laboratory parameters and thorax computed tomography (CT) findings in the course of COVID-19. Twenty-five laboratory-confirmed [reverse transcription-quantitative polimerase chain reaction (RT-qPCR) positive] and 24 clinically diagnosed (RT-qPCR negative) COVID-19 patients were enrolled in the study. Blood specimens were collected for sEPCR and haematological and biochemical parameter measurement. Thorax CT was performed to detect COVID-19 findings. These parameters from RT-qPCR positive and negative patients were then compared. Although there was no difference between the groups in terms of symptoms, the time between the onset of symptoms and the admission time was shorter in RT-qPCR positive group (P?=?0.000). sEPCR levels were significantly higher in the RT-qPCR positive group (P?=?0.011). Patients with ground-glass opacity and bilateral involvement on thorax CT have higher serum sEPCR levels (P?=?0.012 and 0.043, respectively). This study has shown for the first time that serum sEPCR levels, which is a member of coagulation cascade and has also been reported to be associated with inflammation, is higher in patients with positive RT-qPCR test and patients with GGO or bilateral involvement on thorax CT regardless of the PCR result. Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved

The Effect of Grazing Applied in the Different Phenological Stages on Yield and Yield Components of Bread Wheat and Triticale

Bu çalışma, Namık Kemal Üniversitesi, Ziraat Fakültesi, Tarla Bitkileri Bölümü uygulama arazisinde iki yıl (2003-04 and 2004-05) süreyle yürütülmüştür. Araştırmada, iki ekmeklik buğday ve iki tritikale çeşidinin verim ve verim unsurları üzerine, farklı fenolojik dönemlerde yapılan otlatma uygulamalarının (a- otlatılmamış (kontrol), b- bir defa otlatılmış (fide döneminde), c- iki defa otlatılmış (fide dönemi+kardeşlenme dönemi), d- üç defa otlatılmış (fide dönemi+kardeşlenme dönemi+sapa kalkma dönemi)) etkisi incelenmiştir. Denemeler, tesadüf bloklarında bölünmüş parseller deneme deseninde çeşitler ana parselleri, otlatma uygulamaları alt parselleri oluşturacak şekilde kurulmuştur. Otlatma uygulamaları çim biçme makinesiyle simulize edilmiştir. Araştırmadan elde edilen sonuçlara göre; otlatma, araştırmada kullanılan tahıl türlerinin tane verimi ve verim komponentlerini olumsuz yönde etkilemiştir. Tane verimindeki ortalama azalma, bir defa otlatma yapıldığında % 8.43, iki defa otlatma yapıldığında % 16.47 ve üç defa otlatma yapıldığında % 52.57 düzeyinde olmuştur. Tane veriminde meydana gelen azalmalar yıla, türlere, çeşide ve tane hasadından önceki gelişme için kalan süreye bağlı olarak değişmiştir. Tekirdağ koşullarında yürütülen bu çalışmanın sonuçları, bölgede kaba yem açığının olduğu yıllarda ekimden yaklaşık en az 12 hafta sonra erken bahar aylarında ekmeklik buğday ve tritikalenin tane veriminde önemli düşüşlere sebebiyet vermeden bir kez otlatılabileceğini göstermektedir.This study was conducted during two growing seasons, 2003-04 and 2004-05, at experimental farm of Field Crops Department of Agricultural Faculty of Namik Kemal University of Turkey. In the study, the effects of grazing regimes (a. control, b. 1 time grazing. c. 2 times grazing and d. 3 times grazing) on grain yield and related characteristics of 2 bread wheat and 2 triticale cultivars were investigated. The experimental design was split plot on randomized blocks, with cultivars as the main plot and grazing regimes as subplot. Grazing was simulated by lawn cutter. According to the results of the study, grazing regimes significantly reduced grain yield and related characteristics. The average reduction in grain yield was 8.43% in only one time grazed, 16.47 % in 2 times grazed and 52.57% in 3 times grazed plots. The reduction in grain yield varied according to year, species, cultivars and grazing date. The results of the study indicate that approximately 12 weeks after sowing, bread wheat and triticale can be grazed one time in the years when there is a shortage of forage

Histology Laboratory Guide Book

Histology and Embryology education and research are fundamental cornerstones of medical science. Histology, which is the basis of many fields of preclinical and clinical medicine, defines the visual components of cells, tissues and organs at the microscope level. This book, which we have published in the third extended version, provides students with a selection of micrographs created from archive preparations that Hacettepe University Faculty of Medicine Department of Histology and Embryology has been carefully created for more than 50 years. This selection has been prepared with the common effort of our academic staff, research assistants and technicians. The purpose of the book is to guide medical and health sciences students while examining the original preparations under the microscope in the laboratory, to match the functional properties associated with the structure of healthy cells with histochemical staining properties. Each chapter in the book contains brief information of micrographs on the basis of organs, tissues and cells under the relevant technical title. In this edition; we would respectfully like to thank the founder of our department and the first woman dean of medical school of our country, Prof. İlhan Kerse and, all of our retired professors who greatly contributed to our education by showing us the way of science. We also thank our former heads of department Prof. Ülken Örs, Prof. Esin Aşan, Prof. Ayşe Nur Çakar, Prof. Attila Dağdeviren, Prof. Sevda Fatma Müftüoğlu and Prof. Fevziye Figen Kaymaz. On behalf of our department, we wish all our students sincere success.Histoloji ve Embriyoloji, tıp biliminin vazgeçilmez temel taşlarından birisini oluşturur. Tıbbın birçok preklinik ve klinik alanına esas oluşturan histoloji, hücre, doku ve organların mikroskop düzeyinde görsel bileşenlerini tanımlar. Beşinci genişletilmiş basımını yaptığımız bu kitap, Hacettepe Üniversitesi Tıp Fakültesi Histoloji ve Embriyoloji Anabilim Dalı’nın 50 yılı aşkın süredir özenle oluşturduğu arşiv preparatlarından derlenmiş mikrograf seçkisini öğrencilere sunmaktadır. Bu seçki, anabilim dalımız öğretim üyeleri, araştırma görevlileri ve teknisyenlerinin ortak emeği ile hazırlanmıştır. Kitabın amacı; tıp ve sağlık bilimleri öğrencilerine laboratuvarda bu preparatları mikroskop altında incelerken rehberlik etmek, sağlıklı hücrelerin yapıları ile ilişkili işlevsel özelliklerini, histokimyasal boyanma özellikleriyle eşleştirmelerini sağlamaktır. Kitaptaki her bölüm, ilgili teknik başlık ya da sisteme ait preparat mikrografları hakkında organ, doku, hücre temelinde kısa bilgiler vermektedir. Bu baskıda; anabilim dalımızın kurucusu ve ülkemizin ilk kadın tıp fakültesi dekanı Sn. Prof. Dr. İlhan Kerse başta olmak üzere, bizlere bilimin yolunu göstererek yetişmemize katkıda bulunan anabilim dalı başkanlarımız Sn. Prof. Dr. Ülken Örs, Sn. Prof. Dr. Esin Aşan, Sn. Prof. Dr. Ayşe Nur Çakar, Sn. Prof. Dr. Attila Dağdeviren, Sn. Prof. Dr. Sevda Fatma Müftüoğlu, Sn. Prof. Dr. Fevziye Figen Kaymaz’a ve tüm emekli hocalarımıza teşekkür ediyoruz. Anabilim dalımız adına tüm öğrencilerimize içten başarı dileklerimizle

Nation-wide analysis of the impact of Covid-19 pandemic on daily urology practice in Turkey

Objective To present a nation-wide analysis of the workload of urology departments in Turkey week-by-week during Covid-19 pandemic

Nation-wide analysis of the impact of Covid-19 pandemic on daily urology practice in Turkey

Ozkent, Mehmet Serkan/0000-0002-6613-0671; Mercimek, Mehmet Necmettin/0000-0002-0680-4451; karabay, emre/0000-0003-1654-8524; Sen, Volkan/0000-0003-2832-0682; Ceyhan, Erman/0000-0001-8223-6399; Irer, Bora/0000-0002-7719-9033; deger, dogan/0000-0002-5095-7770WOS: 000584084200001PubMed: 32996259Objective To present a nation-wide analysis of the workload of urology departments in Turkey week-by-week during Covid-19 pandemic. Methodology the centres participating in the study were divided into three groups as tertiary referral centres, state hospitals and private practice hospitals. the number of outpatients, inpatients, daily interventions and urological surgeries were recorded prospectively between 9-March-2020 and 31-May-2020. All these variables were recorded for the same time interval of 2019 as well. the weekly change of the workload of urology during pandemic period was evaluated, also the workload of urology and the distributions of certain urological surgeries were compared between the pandemic period and the same time interval of the year 2019. Results A total of 51 centres participated in the study. the number of outpatients, inpatients, urological surgeries and daily interventions were found to be dramatically decreased by the 3rd week of pandemics in state hospitals and tertiary referral centres; however, the daily urological practice were similar in private practice hospitals throughout the pandemic period. When the workload of urology in pandemic period and the same time interval of the year 2019 were compared, a huge decrease was observed in all variables during pandemic period. However, temporary measures like ureteral stenting, nephrostomy placement and percutaneous cystostomy have been found to increase during Covid-19 pandemic compared with normal life. Conclusions Covid-19 pandemic significantly affected the routine daily urological practice likewise other subspecialties and priority was given to emergent and non-deferrable surgeries by urologists in concordance with published clinical guidelines

Withdrawal of Staphylococcus aureus from intensive care units in Turkey

WOS: 000326241700021PubMed ID: 23663858Background: In the past, Staphylococcus aureus infections have displayed various patterns of epidemiologic curves in hospitals, particularly in intensive care units (ICUs). This study aimed to characterize the current trend in a nationwide survey of ICUs in Turkey. Methods: A total of 88 ICUs from 36 Turkish tertiary hospitals were included in this retrospective study, which was performed during the first 3 months of both 2008 (period [P] 1) and 2011 (P2). A P value <=.01 was considered significant. Results: Although overall rates of hospital-acquired infection (HAI) and device-associated infection densities were similar in P1 and P2, the densities of HAIs due to S aureus and methicillin-resistant S aureus (MRSA) were significantly lower in P2 (P < .0001). However, the proportion of HAIs due to Acinetobacter was significantly higher in P2 (P < .0001). Conclusions: The incidence of S aureus infections is declining rapidly in Turkish ICUs, with potential impacts on empirical treatment strategies in these ICUs. Copyright (C) 2013 by the Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved

Incidence and clinical characteristics of acute rheumatic fever in Turkey: Results of a nationwide multicentre study

© 2021 Paediatrics and Child Health Division (The Royal Australasian College of Physicians)Aim: To evaluate the incidence and clinical features of acute rheumatic fever (ARF) in Turkey, following the revised Jones criteria in 2015. Methods: This multicentre study was designed by the Acquired Heart Diseases Working Group of the Turkish Pediatric Cardiology and Pediatric Cardiac Surgery Association in 2016. The data during the first attack of 1103 ARF patients were collected from the paediatric cardiologists between 1 January 2016 and 31 December 2016. Results: Turkey National Institute of Statistics records of 2016 were used for the determination of ARF incidence with regard to various cities and regions separately. The estimated incidence rate of ARF was 8.84/100 000 in Turkey. The ARF incidence varied considerably among different regions. The highest incidence was found in the Eastern Anatolia Region as 14.4/100 000, and the lowest incidence was found in the Black Sea Region as 3.3/100 000 (P < 0.05). Clinical carditis was the most common finding. The incidence of clinical carditis, subclinical carditis, polyarthritis, aseptic monoarthritis, polyarthralgia and Sydenham's Chorea was 53.5%, 29.1%, 52.8%, 10.3%, 18.6% and 7.9%, respectively. The incidences of clinical carditis, subclinical carditis, polyarthritis and polyarthralgia were found to be significantly different among different regions (P < 0.05). Conclusion: The findings of this nationwide screening of ARF suggest that Turkey should be included in the moderate-risk group