57 research outputs found
RĂŽle actuel de la capsule endoscopique dans la dĂ©tection des tumeurs nĂ©oplasiques de lâintestin grĂȘle
Although small-bowel tumors are a small proportion of
gastrointestinal neoplasms recent studies suggest that the
incidence of these diseases is increasing. In fact, using new
diagnostic modalities, their frequency has been shown to be
slightly superior than previously thought. Until recently, diagnosis
and management of these tumors were delayed by the difficult
of access to the small bowel and the poor diagnostic capabilities
of the available diagnostic techniques. An array of new methods
has recently been developed, increasing the possibility of detecting
these tumors at an earlier stage. In this particular subset of
patients capsule endoscopy, despite its possible limitations,
may provide crucial information changing the subsequent
patient management and possibly influencing the long-term
clinical outcome.Bien que les tumeurs de lâintestin grĂȘle ne reprĂ©sentent quâune
faible proportion des lésions néoplasiques du tractus digestif, de
récentes études ont mis en évidence une légÚre augmentation de
leur incidence. En fait, grùce aux nouvelles modalités diagnostiques,
leur frĂ©quence sâest avĂ©rĂ©e lĂ©gĂšrement supĂ©rieure Ă ce qui
Ă©tait prĂ©cĂ©demment rapportĂ©. JusquâĂ trĂšs rĂ©cemment, le
diagnostic et la prise en charge de ces tumeurs étaient retardés
en raison dâun accĂšs difficile Ă lâintestin grĂȘle et aux faibles
capacités diagnostiques des moyens techniques disponibles.
Tout un éventail de nouvelles méthodes ont récemment été mises
au point, améliorant la possibilité de détecter ces lésions à un
stade plus précoce. Pour cette catégorie spécifique de patients
avec lĂ©sions de lâintestin grĂȘle, la capsule endoscopique, en dĂ©pit
de ses limites, peut fournir une information cruciale influant par
conséquent sur la prise en charge du patient et sur les résultats
cliniques au long cours
Recent developments in small bowel endoscopy: the âblack boxâ is now open!
Over the last few years, capsule endoscopy has been established as a fundamental device in the practicing gastroenterologistâs toolbox. Its utilization in diagnostic algorithms for suspected small bowel bleeding, Crohnâs disease, and small bowel tumors has been approved by several guidelines. The advent of double-balloon enteroscopy has significantly increased the therapeutic possibilities and release of multiple devices (single-balloon enteroscopy and spiral enteroscopy) aimed at improving the performance of small bowel enteroscopy. Recently, some important innovations have appeared in the small bowel endoscopy scene, providing further improvement to its evolution. Artificial intelligence in capsule endoscopy should increase diagnostic accuracy and reading efficiency, and the introduction of motorized spiral enteroscopy into clinical practice could also improve the therapeutic yield. This review focuses on the most recent studies on artificial-intelligence-assisted capsule endoscopy and motorized spiral enteroscopy
Improving Diagnostic Yield of Capsule Endoscopy in Coeliac Disease: Can Flexible Spectral Imaging Colour Enhancement Play a Role?
Introduction: Flexible spectral imaging colour enhancement (FICE) is a form of virtual chromoendoscopy that is incorporated in the capsule reading software and that can be used by reviewers to enhance the delineation of lesions in the small bowel. This has been shown to be useful in the detection of pigmented (ulcers, angioectasias) lesions. However, its application to coeliac disease (CD) images from small bowel capsule endoscopies (SBCEs) has rarely been studied. Methods: This was a European, multicentre study that included 5 expert capsule reviewers who were asked to evaluate a number of normal and abnormal de-identified images from SBCEs of patients with CD to determine whether the use of FICE and blue light can improve the detection of CD-related changes. Results: Sensitivity and specificity of conventional white light in the delineation of CD-related changes were 100%. The next best image modification was FICE 1 with a sensitivity of 80% and a specificity of 100%. There was no difference between conventional white light, FICE and blue light for the identification of CD-related changes. There was a low agreement (Fleiss kappa 0.107; p = 0.147) between expert reviewers in selecting the best image modification that detected CD-related changes. Conclusions: FICE and blue light were not found to be superior to conventional white light in the delineation of macroscopic changes related to CD on SBCEs
Small-bowel capsule endoscopy with panoramic view: results of the first multicenter, observational study (with videos).
BACKGROUND AND AIMS: The first small-bowel video-capsule endoscopy (VCE) with 360° panoramic view has been recently developed. This new capsule has a wire-free technology, 4 high frame-rate cameras, and a long-lasting battery life. The present study was aimed at assessing performances and the safety profile of the 360° panoramic-view capsule in a large series of patients from a multicenter clinical practice setting. METHODS: Consecutive patients undergoing a 360° panoramic-view capsule procedure in 7 European Institutions between January 2011 and November 2015 were included. Both technical (ie, technical failures, completion rate) and clinical (ie, indication, findings, retention rate) data were collected by means of a structured questionnaire. VCE findings were classified according to the likelihood to explain reason for referral: P0-low, P1-intermediate and P2-high. RESULTS: Among 172 patients (94 men; median age: 68 years, IQR: 53-75), 142 underwent VCE for obscure (32 overt, 110 occult) GI bleeding (OGIB) and 28 for suspected (17) or established (2) Crohn's disease (CD). Overall, 560 findings were detected; 252 of them were P2. The overall diagnostic yield was 40.1%; 42.2% and 30.0% in patients with OGIB and CD, respectively. The rate of complete enteroscopy was 90.2%. All of the patients but one, who experienced capsule retention (1/172: 0.6%), excreted and retrieved the capsule. VCE failure occurred in 4 of 172 (2.3%) cases for technical problems. CONCLUSION: The present multicenter study, conducted in clinical practice setting and based on a large consecutive series of patients, showed that DY and safety profile of 360° panoramic-view capsule are similar to those of forward-view VCEs
Quality performance measures for small capsule endoscopy: Are the ESGE quality standards met?
Background and study aims The European Society of Gastrointestinal Endoscopy (ESGE) recently issued a quality performance measures document for small bowel capsule endoscopy (SBCE). The aim of this nationwide survey was to explore SBCE practice with ESGE quality measures as a benchmark.
Patients and methods A dedicated per-center semiquantitative questionnaire based on ESGE performance measures for SBCE was created by a group of SBCE experts. One-hundred-eighty-one centers were invited to participate and were asked to calculate performance measures for SBCE performed in 2018. Data were compared with 10 ESGE quality standards for both key and minor performance measures.
Results Ninety-one centers (50.3 %) participated in the data collection. Overall in the last 5 years (2014â2018), 26,615 SBCEs were performed, 5917 of which were done in 2018. Eighty percent or more of the participating centers reached the minimum standard established by the ESGE Small Bowel Working Group (ESBWG) for four performance measures (indications for SBCE, complete small bowel evaluation, diagnostic yield and retention rate). Conversely, compliance with six minimum standards established by ESBWG concerning adequate bowel preparation, patient selection, timing of SBCE in overt bleeding, appropriate reporting,
reading protocols and referral to device-assisted enteroscopy was met by only 15.5%, 10.9%, 31.1%, 67.7%, 53.4%, and 32.2% of centers, respectively.
Conclusions The present survey shows significant variability across SBCE centers; only four (4/10: 40 %) SBCE procedural minimum standards were met by a relevant proportion of the centers ( â„ 80 %). Our data should help in identifying target areas for quality improvement programs in SBCE
KID Project:an internet-based digital video atlas of capsule endoscopy for research purposes
BACKGROUND AND AIMS:
Capsule endoscopy (CE) has revolutionized small-bowel (SB) investigation. Computational methods can enhance diagnostic yield (DY); however, incorporating machine learning algorithms (MLAs) into CE reading is difficult as large amounts of image annotations are required for training. Current databases lack graphic annotations of pathologies and cannot be used. A novel database, KID, aims to provide a reference for research and development of medical decision support systems (MDSS) for CE.
METHODS:
Open-source software was used for the KID database. Clinicians contribute anonymized, annotated CE images and videos. Graphic annotations are supported by an open-access annotation tool (Ratsnake). We detail an experiment based on the KID database, examining differences in SB lesion measurement between human readers and a MLA. The Jaccard Index (JI) was used to evaluate similarity between annotations by the MLA and human readers.
RESULTS:
The MLA performed best in measuring lymphangiectasias with a JI of 81\u200a\ub1\u200a6\u200a%. The other lesion types were: angioectasias (JI 64\u200a\ub1\u200a11\u200a%), aphthae (JI 64\u200a\ub1\u200a8\u200a%), chylous cysts (JI 70\u200a\ub1\u200a14\u200a%), polypoid lesions (JI 75\u200a\ub1\u200a21\u200a%), and ulcers (JI 56\u200a\ub1\u200a9\u200a%).
CONCLUSION:
MLA can perform as well as human readers in the measurement of SB angioectasias in white light (WL). Automated lesion measurement is therefore feasible. KID is currently the only open-source CE database developed specifically to aid development of MDSS. Our experiment demonstrates this potential
Inter/intra-observer agreement in video-capsule endoscopy : are we getting it all wrong? A systematic review and meta-analysis
Video-capsule endoscopy (VCE) reading is a time- and energy-consuming task. Agreement
on findings between readers (either different or the same) is a crucial point for increasing performance
and providing valid reports. The aim of this systematic review with meta-analysis is to provide
an evaluation of inter/intra-observer agreement in VCE reading. A systematic literature search in
PubMed, Embase and Web of Science was performed throughout September 2022. The degree of
observer agreement, expressed with different test statistics, was extracted. As different statistics are
not directly comparable, our analyses were stratified by type of test statistics, dividing them in groups
of âNone/Poor/Minimalâ, âModerate/Weak/Fairâ, âGood/Excellent/Strongâ and âPerfect/Almost
perfectâ to report the proportions of each. In total, 60 studies were included in the analysis, with
a total of 579 comparisons. The quality of included studies, assessed with the MINORS score, was
sufficient in 52/60 studies. The most common test statistics were the Kappa statistics for categorical
outcomes (424 comparisons) and the intra-class correlation coefficient (ICC) for continuous outcomes
(73 comparisons). In the overall comparison of inter-observer agreement, only 23% were evaluated as
âgoodâ or âperfectâ; for intra-observer agreement, this was the case in 36%. Sources of heterogeneity
(high, I2 81.8â98.1%) were investigated with meta-regressions, showing a possible role of country,
capsule type and year of publication in Kappa inter-observer agreement. VCE reading suffers from
substantial heterogeneity and sub-optimal agreement in both inter- and intra-observer evaluation.
Artificial-intelligence-based tools and the adoption of a unified terminology may progressively
enhance levels of agreement in VCE reading.peer-reviewe
Capsule endoscopy in neoplastic diseases
Until recently, diagnosis and management of small-bowel tumors were delayed by the difficulty of access to the small bowel and the poor diagnostic capabilities of the available diagnostic techniques. An array of new methods has recently been developed, increasing the possibility of detecting these tumors at an earlier stage. Capsule endoscopy (CE) appears to be an ideal tool to recognize the presence of neoplastic lesions along this organ, since it is non-invasive and enables the entire small bowel to be visualized. High-quality images of the small-bowel mucosa may be captured and small and flat lesions recognized, without exposure to radiation. Recent studies on a large population of patients undergoing CE have reported small-bowel tumor frequency only slightly above that reported in previous surgical series (range, 1.6%-2.4%) and have also confirmed that the main clinical indication to CE in patients with small-bowel tumors is obscure gastrointestinal (GI) bleeding. The majority of tumors identified by CE are malignant; many were unsuspected and not found by other methods. However, it remains difficult to identify pathology and tumor type based on the lesionâs endoscopic appearance. Despite its limitations, CE provides crucial information leading in most cases to changes in subsequent patient management. Whether the use of CE in combination with other new diagnostic (MRI or multidetector CT enterography) and therapeutic (Push-and-pull enteroscopy) techniques will lead to earlier diagnosis and treatment of these neoplasms, ultimately resulting in a survival advantage and in cost savings, remains to be determined through carefully-designed studies
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