How the Differential Vulnerability of the Elderly Hinders Wider Community Capacity for Resilient Adaptation on the Atlantic and Gulf Coasts.

&nbsp; The occurrence of new and more frequent natural hazard events spurred by climate change necessitates that communities along the U.S. Atlantic and Gulf coasts respond with equitable and effective strategies for resilient adaptation. To understand how current resilient adaptation strategies, fail to comprehensively address the vulnerability of marginalized populations, this paper concentrates on the differential vulnerability of elderly coastal community members. The elderly is a demographically diverse population that consists of individuals in every social, political, economic, and cultural group within the Atlantic and Gulf regions. My research evaluates how the health and socioeconomic well-being of this population detrimentally impacts their ability to carry out three resilient adaptation strategies: evacuation, reconstruction, and managed retreat. I argue that the intersectionality of this population reveals that the failure to address the elderly&rsquo;s susceptibility to coastal risks, breaks down the resilient capacity of coastal communities as a whole.</p

Palliative care of children with brain tumors: A parental perspective

Objective: To explore the end-of-life experience of children with brain tumors and their families. Design: Qualitative analysis of focus group interviews. Setting: Children\u27s Hospital, London Health Sciences Center. Participants: Twenty-five parents of 17 children who had died of brain tumors. Intervention: Parents participated in 3 semistructured focus group interviews. Main Outcome Measures: Themes identified through thematic analysis of interview transcripts. Results: Qualitative analysis identified 3 primary themes. (1) Parents described the dying trajectory of their child as characterized by progressive neurologic deterioration, with the loss of the ability to communicate as a turning point. Parental coping mechanisms included striving to maintain normality and finding spiritual strength through maintaining hope and in the resilience of their child. (2) Parental struggles during this phase included balancing competing responsibilities and speaking with their child about death. (3) Barriers to achieving a home death included suboptimal symptom management, financial and practical hardships, and inadequate community support. A fourth, secondary theme concerned the therapeutic benefits of the interview. Conclusion: The neurologic deterioration that characterizes the dying trajectory of children with brain tumors may create significant challenges for health care professionals and the children\u27s parents, supporting the need for increased awareness of the distinct issues in the palliative care of children with brain tumors and for early anticipatory guidance provided for families. ©2010 American Medical Association. All rights reserved

Optical Properties of High-Frequency Radio Sources from the Australia Telescope 20 GHz (AT20G) Survey

Our current understanding of radio-loud AGN comes predominantly from studies at frequencies of 5 GHz and below. With the recent completion of the Australia Telescope 20 GHz (AT20G) survey, we can now gain insight into the high-frequency radio properties of AGN. This paper presents supplementary information on the AT20G sources in the form of optical counterparts and redshifts. Optical counterparts were identified using the SuperCOSMOS database and redshifts were found from either the 6dF Galaxy survey or the literature. We also report 144 new redshifts. For AT20G sources outside the Galactic plane, 78.5% have optical identifications and 30.9% have redshift information. The optical identification rate also increases with increasing flux density. Targets which had optical spectra available were examined to obtain a spectral classification. There appear to be two distinct AT20G populations; the high luminosity quasars that are generally associated with point-source optical counterparts and exhibit strong emission lines in the optical spectrum, and the lower luminosity radio galaxies that are generally associated with passive galaxies in both the optical images and spectroscopic properties. It is suggested that these different populations can be associated with different accretion modes (cold-mode or hot-mode). We find that the cold-mode sources have a steeper spectral index and produce more luminous radio lobes, but generally reside in smaller host galaxies than their hot-mode counterparts. This can be attributed to the fact that they are accreting material more efficiently. Lastly, we compare the AT20G survey with the S-cubed semi-empirical (S3-SEX) models and conclude that the S3-SEX models need refining to correctly model the compact cores of AGN. The AT20G survey provides the ideal sample to do this.Comment: Accepted for publication in MNRA

Opening the doors of possibility for gifted/high-ability children with learning difficulties: Preliminary assessment strategies for primary school teachers

The traits linked to gifted children with learning disabilities (twice-exceptional) are diverse and complex. Identification of these children can be hindered by a combination of factors, including variations in teacher knowledge and experience, inconsistencies in the visibility of high abilities coexisting simultaneously with one or more learning disabilities, and also the lack of a practical assessment tool. This mixed-methods study addresses the need for such a tool and other assessment strategies that primary school teachers can implement in the preliminary exploratory stage of identifying possible twice-exceptional children. In this process, the focus centres on learning strengths and difficulties. The first phase of the Study focused on procedures leading to the development and trialling of a comprehensive and useful teacher checklist questionnaire (TCQ). Its comprehensiveness was developed through reviewing research-based characteristics, anecdotal lists and teacher perceptions. Section A of the TCQ is based on the six natural-ability Domains found in Françoys Gagné's Differentiated Model of Giftedness and Talent (DMGT 2.0; 2008) or, more recently, his Expanded Model of Talent Development (EMTD, 2013). Section B has three familiar categories of learning difficulties known within the context of the primary school. In the trialling phase, ten teacher participants trialled the TCQ and ranked the selected children in their classes on every item in the nine categories. Overall, qualitative and quantitative analyses suggest promising trends in the preliminary investigation into the TCQ's internal reliability, validity and practical usefulness. In the second phase, six child participants were selected for case studies to determine whether other assessment strategies supported the findings of the TCQ. The results from Interviews with each child, a Parent/Teacher Questionnaire, a non-verbal intelligence test (Raven's Standard Progressive Matrices), and a Think-aloud protocol, affirm the worthiness of the TCQ, but variations in results suggest the importance of its inclusion as part of a comprehensive assessment protocol

Geology and palaeontology of the Hindon Maar Complex: A Miocene terrestrial fossil Lagerstätte in southern New Zealand

Highlights • Hindon Maar Complex is a new mid-Miocene Fossil-Lagerstätte in New Zealand. • Anoxia in maar lakes allowed exquisite preservation of plant and animal fossils. • The biota is from a lake and Nothofagus/podocarp/mixed broadleaf forest ecosystem. • Fossils record high diversity at humid, warm Southern Hemisphere mid-latitudes. Abstract This paper highlights the geology, biodiversity and palaeoecology of the Hindon Maar Complex, the second Miocene Konservat-Lagerstätte to be described from New Zealand. The Lagerstätte comprises four partly eroded maar-diatreme volcanoes, with three craters filled by biogenic and highly fossiliferous lacustrine sediments. The exceptionally well-preserved and diverse biota from the site is derived from a mid-latitude Southern Hemisphere lake-forest palaeoecosystem, including many fossil taxa not previously reported from the Southern Hemisphere. The most common macrofossils are leaves of Nothofagus, but the flora also includes conifers, cycads, monocots (such as Ripogonum and palms), together with Lauraceae, Myrtaceae and Araliaceae leaves and flowers. The small maar lakes were surrounded by Nothofagus/podocarp/mixed broadleaf forest growing under humid, warm temperate to subtropical conditions. The fossil fauna comprises insects in the orders Odonata, Hemiptera, Thysanoptera, Coleoptera, Diptera, Hymenoptera and Trichoptera, and the fish assemblage includes a non-migratory species of the Southern Hemisphere Galaxias (Galaxiidae) and a significant new record of the freshwater eel Anguilla (Anguillidae). The fossil assemblage also includes the first pre-Quaternary bird feathers from New Zealand and abundant coprolites derived from fish and volant birds, presumably waterfowl. Palynomorph analysis and a 40Ar/39Ar age of 14.6 Ma obtained from basanite associated with the maar complex indicate that the Hindon Maar Complex is of mid-Miocene age (Langhian; New Zealand local stage: Lillburnian). It thus provides a new and unique perspective on Neogene terrestrial biodiversity and biogeography in the Australasian region, around the end of the mid-Miocene thermal optimum and prior to late Miocene–Pleistocene climate cooling episodes when many warm-temperate and subtropical forest components became extinct in New Zealand

Development and Assessment of a Diagnostic DNA Oligonucleotide Microarray for Detection and Typing of Meningitis-Associated Bacterial Species.

Meningitis is commonly caused by infection with a variety of bacterial or viral pathogens. Acute bacterial meningitis (ABM) can cause severe disease, which can progress rapidly to a critical life-threatening condition. Rapid diagnosis of ABM is critical, as this is most commonly associated with severe sequelae with associated high mortality and morbidity rates compared to viral meningitis, which is less severe and self-limiting. We have designed a microarray for detection and diagnosis of ABM. This has been validated using randomly amplified DNA targets (RADT), comparing buffers with or without formamide, in glass slide format or on the Alere ArrayTubeTM (Alere Technologies GmbH) microarray platform. Pathogen-specific signals were observed using purified bacterial nucleic acids and to a lesser extent using patient cerebral spinal fluid (CSF) samples, with some technical issues observed using RADT and glass slides. Repurposing the array onto the Alere ArrayTubeTM platform and using a targeted amplification system increased specific and reduced nonspecific hybridization signals using both pathogen nucleic and patient CSF DNA targets, better revealing pathogen-specific signals although sensitivity was still reduced in the latter. This diagnostic microarray is useful as a laboratory diagnostic tool for species and strain designation for ABM, rather than for primary diagnosis

Constrained patterns of covariation and clustering of HIV-1 non-nucleoside reverse transcriptase inhibitor resistance mutations

Objectives:We characterized pairwise and higher order patterns of non-nucleoside reverse transcriptase inhibi-tor (NNRTI)-selected mutations because multiple mutations are usually required for clinically significant resist-ance to second-generation NNRTIs. Patients and methods: We analysed viruses from 13039 individuals with sequences containing at least one of 52 published NNRTI-selected mutations, including 1133 viruses from individuals who received efavirenz but no other NNRTI and 1510 viruses from individuals who received nevirapine but no other NNRTI. Of the 17 reported etravirine resistance-associated mutations (RAMs), Y181C/I/V, L100I, K101P and M230L were considered major based on published in vitro susceptibility data

The low density and magnetization of a massive galaxy halo exposed by a fast radio burst

Present-day galaxies are surrounded by cool and enriched halo gas extending to hundreds of kiloparsecs. This halo gas is thought to be the dominant reservoir of material available to fuel future star formation, but direct constraints on its mass and physical properties have been difficult to obtain. We report the detection of a fast radio burst (FRB 181112) with arcsecond precision, which passes through the halo of a foreground galaxy. Analysis of the burst shows the halo gas has low net magnetization and turbulence. Our results imply predominantly diffuse gas in massive galactic halos, even those hosting active supermassive black holes, contrary to some previous results.Comment: Published in Science on 2019 September 26; Main (3 figures; 1 Table) + Supp (12 figures; 7 Tables

Limits on precursor and afterglow radio emission from a fast radio burst in a star-forming galaxy

We present a new fast radio burst at 920 MHz discovered during commensal observations conducted with the Australian Square Kilometre Array Pathfinder (ASKAP) as part of the Commensal Real-time ASKAP Fast Transients (CRAFT) survey. FRB 191001 was detected at a dispersion measure (DM) of 506.92(4) pc cm$^{-3}$ and its measured fluence of 143(15) Jy ms is the highest of the bursts localized to host galaxies by ASKAP to date. The sub-arcsecond localisation of the FRB provided by ASKAP reveals that the burst originated in the outskirts of a highly star-forming spiral in a galaxy pair at redshift $z=0.2340(1)$. Radio observations show no evidence for a compact persistent radio source associated with the FRB 191001 above a flux density of $15\mu$Jy. However, we detect diffuse synchrotron radio emission from the disk of the host galaxy that we ascribe to ongoing star formation. FRB 191001 was also detected as an image-plane transient in a single 10-s snapshot with a flux density of 19.3 mJy in the low-time-resolution visibilities obtained simultaneously with CRAFT data. The commensal observation facilitated a search for repeating and slowly varying radio emissions 8 hrs before and 1 hr after the burst. We found no variable radio emission on timescales ranging from 1 ms to 1.4 hr. We report our upper limits and briefly review FRB progenitor theories in the literature which predict radio afterglows. Our data are still only weakly constraining of any afterglows at the redshift of the FRB. Future commensal observations of more nearby and bright FRBs will potentially provide stronger constraints.Comment: 12 pages, 6 figures, Accepted for publication in ApJ Letter