Mother to daughter transmission of Female Genital Cutting in Egypt, Burkina Faso and Senegal

The aim of article is to assess the determinants of mothers to daughters transmission of female genital cutting (FGC) in Senegal, Burkina Faso and Egypt. Using the most recent DHS surveys the study confirms that the main dimension related to daughters’ circumcision is mother’s personal experience as circumcised mothers more likely to perpetrate the practice on daughters. Policies aim at changing this social norm could therefore generate a virtuous circle: for each child who is not circumcised, a risk-free third-generation is projected. Factors related to women’s empowerment as better education, higher autonomy and wealth of the family as well social environment against FGC also discourage the continuation of the practice and protect daughters from the risk to be circumcised in each country analyzed.

Analisi di una pratica di insegnamento: il dettato nelle classi prime della Scuola Primaria

Today as never before, the ongoing social and cultural claim pedagogists to move in a direction in which theory and practice are closely related, in order to undertake research that can face the «real problems» involving training agencies.In order to avoid the risk of a disconnection between theory and practice, the research presented here - still in progress - aims to observe, describe and analyze the practice of the dictation in 13 first classes of Primary School. This teaching npractice, still widespread despite its absence from the most recent MinisterialDirections, needs to be deeply investigated: why do teachers dictate? Is dictation still useful in a society where many students come to school already literate or speak languages in which the phoneme-grapheme relationship is not as clear as in the Italian language?Starting from Emilia Ferreiro’s psychogenetic research on the acquisition of written language, this paper aims to understand the reasons that lead teachers to use the dictation, and the implications that this practice has on the process of acquisition of written languageMai come oggi i continui cambiamenti sociali e culturali chiedono alla pedagogia di muoversi in una direzione in cui teoria e prassi siano in stretta relazione, nell’ottica di avviare ricerche capaci di affrontare i «problemi viventi» che coinvolgono le agenzie formative.Proprio per evitare i rischi di uno scollamento tra teoria e prassi la ricerca qui presentata – ancora in fieri – si pone come obiettivo quello di osservare, descrivere e analizzare la pratica del dettato in tredici classi prime della Scuola Primaria. Tale pratica di insegnamento, ancora molto diffusa nonostante la sua assenzadalle più recenti Indicazioni Ministeriali, richiede di essere maggiormente investigata: perché le insegnanti dettano? È ancora utile il dettato in una società dove molti alunni giungono a scuola già alfabetizzati o parlano lingue in cui il rapporto fonema-grafema non è così diretto come nella lingua italiana?Partendo dalle ricerche psicogenetiche di Emilia Ferreiro relative all’acquisizione della lingua scritta, il presente lavoro si propone di comprendere non solo le ragioni che spingono le insegnanti a utilizzare il dettato, ma anche la ricaduta che tale pratica può avere nel processo di acquisizione della lingua scritta

Quantum Multi-Model Fitting

Geometric model fitting is a challenging but fundamental computer vision problem. Recently, quantum optimization has been shown to enhance robust fitting for the case of a single model, while leaving the question of multi-model fitting open. In response to this challenge, this paper shows that the latter case can significantly benefit from quantum hardware and proposes the first quantum approach to multi-model fitting (MMF). We formulate MMF as a problem that can be efficiently sampled by modern adiabatic quantum computers without the relaxation of the objective function. We also propose an iterative and decomposed version of our method, which supports real-world-sized problems. The experimental evaluation demonstrates promising results on a variety of datasets. The source code is available at: https://github.com/FarinaMatteo/qmmf.Comment: In Computer Vision and Pattern Recognition (CVPR) 2023; Highligh

Influence of Storage Temperature on Radiochemical Purity of 99mTc-Radiopharmaceuticals

The influence of effective room temperature on the radiochemical purity of 99mTc-radiopharmaceuticals was reported. This study was born from the observation that in the isolators used for the preparation of the 99mTc-radiopharmaceuticals the temperatures can be higher than those reported in the commercial illustrative leaflets of the kits. This is due, in particular, to the small size of the work area, the presence of instruments for heating, the continuous activation of air filtration, in addition to the fact that the environment of the isolator used for the 99mTc-radiopharmaceuticals preparation and storage is completely isolated and not conditioned. A total of 244 99mTc-radiopharmaceutical preparations (seven different types) have been tested and the radiochemical purity was checked at the end of preparation and until the expiry time. Moreover, we found that the mean temperature into the isolator was significantly higher than 25 C, the temperature, in general, required for the preparation and storage of 99mTc-radiopharmaceuticals. Results confirmed the radiochemical stability of radiopharmaceutical products. However, as required in the field of quality assurance, the impact that different conditions than those required by the manufacturer on the radiopharmaceuticals quality have to be verified before human administration

Validation of a mechanistic model for predicting fruit scab infection on different loquat cultivars

Scab, caused by Fusicladium eriobotryae, is the main disease affecting loquat (Eriobotrya japonica) in the Mediterranean basin. A mechanistic epidemiological model developed in Spain to predict infection of loquat fruit by conidia was assessed in the main loquat cultivated area of Italy (Sicily). A 3-year study (2014–2016) was carried out in an experimental orchard on three loquat cultivars: Algerie, Peluche and San Filipparo. For each cultivar, output of the model was compared with observed scab development on fruits. The scab epidemics observed were different in different years and cultivars, representing a suitable data set for model validation. The model correctly predicted loquat scab, as demonstrated by the goodness of fit between model predictions and observed disease incidence on fruits (R2 > 0.85), confirming the accuracy and robustness of the model for predicting scab development in loquat orchards. The use of the model for fungicide scheduling against F. eriobotryae may improve the management of loquat scab by reducing the number of required fungicide applications

Effects induced by particles derived from two anthropogenic sources on respiratory, cardiovascular and central nervous systems

Air pollution represents a well-known environmental problem related to public health. Particulate matter (PM) is a heterogeneous mixture of chemicals, metals and soils. Its adverse effects have been correlated with particles size, being smaller particles more likely to cause a worst damage, so their study deserves more attention. Ultrafine particles (UFPs, dae < 100 nm) are short-lived particles dispersed in the environment. In Lombardy, diesel combustion and solid biomass burning are the most relevant contributors to primary UFPs emissions (15-30 nm in diameter). Toxicological studies, mainly in vitro, indicate specific effects for particles of different origin but comparative in vivo studies are scarce. PM exposure has been primarily associated to pulmonary and cardiovascular diseases through oxidative stress and inflammatory response, but recently it has been postulated that PM exposure could also be an important risk factor for neurotoxicity and could have a role in neurodegenerative diseases. In this study we analysed in BALB/c mice the effect of single and repeated intratracheal instillation of diesel (DEP) and biomass (BC) particles on respiratory, cardiovascular and central nervous systems, comparing the two different UFPs sources. The study was performed at biochemical and histopathological level. Different pro-inflammatory, cytotoxic, pro-coagulant and oxidative stress markers were measured. For the histopathological evaluation, sections of lung, heart and different parts of the central nervous system (CNS) were examined at light microscope, using standard staining tecniques and immunohistochemical methods. Inflammation was also monitored in living mice following BC or DEP intratracheal repeated administration using the FMT 1500 fluorescence tomography imaging system and the MMPSense 750 Fast probe.  Our results indicate that even a single instillation of both the sources of UFPs induces a wide range of biochemical changes in the respiratory and cardiovascular systems, then confirmed by repeated instillation. In the CNS similar modifications were observed, although these were much more evident after repeated instillations. Histological examination demonstrated the presence of macrophages containing particles in the lungs after UFPs single and, more abundantly, repeated administration. However, significant changes were not observed in sections of heart and CNS. DEP was more effective in inducing oxidative stress and inflammation compared to BC

The Evolution of O i over 3.2 < z < 6.5: Reionization of the Circumgalactic Medium

We present a survey for metal absorption systems traced by neutral oxygen over 3.2 0.05 Å, of which there are 49 nonproximate systems in our sample. We find that the number density does not monotonically increase with decreasing redshift, as would naively be expected from the buildup of metal-enriched circumgalactic gas with time. The number density over 4.9 < z < 5.7 is a factor of 1.7–4.1 lower (68% confidence) than that over 5.7 < z < 6.5, with a lower value at z < 5.7 favored with 99% confidence. This decrease suggests that the fraction of metals in a low-ionization phase is larger at z ~ 6 than at lower redshifts. Absorption from highly ionized metals traced by C iv is also weaker in higher-redshift O i systems, supporting this picture. The evolution of O i absorbers implies that metal-enriched circumgalactic gas at z ~ 6 is undergoing an ionization transition driven by a strengthening ultraviolet background. This in turn suggests that the reionization of the diffuse intergalactic medium may still be ongoing at or only recently ended by this epoch

GEN-O-MA project: an Italian network studying clinical course and pathogenic pathways of moyamoya disease—study protocol and preliminary results

Background: GENetics of mOyaMoyA (GEN-O-MA) project is a multicenter observational study implemented in Italy aimed at creating a network of centers involved in moyamoya angiopathy (MA) care and research and at collecting a large series and bio-repository of MA patients, finally aimed at describing the disease phenotype and clinical course as well as at identifying biological or cellular markers for disease progression. The present paper resumes the most important study methodological issues and preliminary results. Methods: Nineteen centers are participating to the study. Patients with both bilateral and unilateral radiologically defined MA are included in the study. For each patient, detailed demographic and clinical as well as neuroimaging data are being collected. When available, biological samples (blood, DNA, CSF, middle cerebral artery samples) are being also collected for biological and cellular studies. Results: Ninety-eight patients (age of onset mean ± SD 35.5 ± 19.6 years; 68.4% females) have been collected so far. 65.3% of patients presented ischemic (50%) and haemorrhagic (15.3%) stroke. A higher female predominance concomitantly with a similar age of onset and clinical features to what was reported in previous studies on Western patients has been confirmed. Conclusion: An accurate and detailed clinical and neuroimaging classification represents the best strategy to provide the characterization of the disease phenotype and clinical course. The collection of a large number of biological samples will permit the identification of biological markers and genetic factors associated with the disease susceptibility in Italy