12 research outputs found

    Simultaneous, Full Characterization of a Single-Photon State

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    As single-photon sources become more mature and are used more often in quantum information, communications, and measurement applications, their characterization becomes more important. Single-photon-like light is often characterized by its brightness, as well as two quantum properties: the suppression of multiphoton content and the photon indistinguishability. While it is desirable to obtain these quantities from a single measurement, currently two or more measurements are required. Here, we show that using two-photon (n=2) number-resolving detectors, one can completely characterize single-photon-like states in a single measurement, where previously two or more measurements were necessary. We simultaneously determine the brightness, the suppression of multiphoton states, the indistinguishability, and the statistical distribution of Fock states to third order for a quantum light source. We find n≥3 number-resolving detectors provide no additional advantage in the single-photon characterization. The new method extracts more information per experimental trial than a conventional measurement for all input states and is particularly more efficient for statistical mixtures of photon states. Thus, using this n=2, number-resolving detector scheme will provide advantages in a variety of quantum optics measurements and systems

    Prevalence of DPYD

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    A high quality draft consensus sequence of the genome of a heterozygous grapevine variety

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    Worldwide, grapes and their derived products have a large market. The cultivated grape species Vitis vinifera has potential to become a model for fruit trees genetics. Like many plant species, it is highly heterozygous, which is an additional challenge to modern whole genome shotgun sequencing. In this paper a high quality draft genome sequence of a cultivated clone of V. vinifera Pinot Noir is presented. We estimate the genome size of V. vinifera to be 504.6 Mb. Genomic sequences corresponding to 477.1 Mb were assembled in 2,093 metacontigs and 435.1 Mb were anchored to the 19 linkage groups (LGs). The number of predicted genes is 29,585, of which 96.1% were assigned to LGs. This assembly of the grape genome provides candidate genes implicated in traits relevant to grapevine cultivation, such as those influencing wine quality, via secondary metabolites, and those connected with the extreme susceptibility of grape to pathogens. Single nucleotide polymorphism (SNP) distribution was consistent with a diffuse haplotype structure across the genome. Of around 2,000,000 SNPs, 1,751,176 were mapped to chromosomes and one or more of them were identified in 86.7% of anchored genes. The relative age of grape duplicated genes was estimated and this made possible to reveal a relatively recent Vitis-specific large scale duplication event concerning at least 10 chromosomes (duplication not reported before). Sanger shotgun sequencing and highly efficient sequencing by synthesis (SBS), together with dedicated assembly programs, resolved a complex heterozygous genome. A consensus sequence of the genome and a set of mapped marker loci were generated. Homologous chromosomes of Pinot Noir differ by 11.2% of their DNA (hemizygous DNA plus chromosomal gaps). SNP markers are offered as a tool with the potential of introducing a new era in the molecular breeding of grape

    The genome of the domesticated apple (Malus x domestica Borkh.)

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    We report a high-quality draft genome sequence of the domesticated apple (Malus x domestica). We show that a relatively recent (> 50 million years ago) genome-wide duplication (GWD) has resulted in the transition from nine ancestral chromosomes to 17 chromosomes in the Pyreae. Traces of older GWDs partly support the monophyly of the ancestral paleohexaploidy of eudicots. Phylogenetic reconstruction of Pyreae and the genus Malus, relative to major Rosaceae taxa, identified the progenitor of the cultivated apple as M. sieversii. Expansion of gene families reported to be involved in fruit development may explain formation of the pome, a Pyreae-specific false fruit that develops by proliferation of the basal part of the sepals, the receptacle. In apple, a subclade of MADS-box genes, normally involved in flower and fruit development, is expanded to include 15 members, as are other gene families involved in Rosaceae-specific metabolism, such as transport and assimilation of sorbitol
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