Evaluación financiera y económica del periodo 2014 al 2017 y propuesta de un plan financiero para la empresa “Agropecuaria Chimú S.R.L”, Trujillo – 2018

En el presente trabajo de investigación se ha planteado como objetivo general: Desarrolar una evaluación financiera y económica del periodo 2014 al 2017, y una propuesta de un Plan Financiero para la Empresa Agropecuaria Chimú S.R.L. Para el logro de dicho objetivo general se ha aplicado los siguientes objetivos específicos; Analizar la situación financiera y económica de los periodos 2014 al 2017, a través del método vertical y horizontal; comparar e interpretar los resultados a través de la aplicación de ratios; y por último plantear como propuesta un plan financiero que sirva como herrmamienta de apoyo para la empresa. Por otra parte la población esta conformada por los Estados de Situación Financiera y los Estados de Resultados desde el periodo 1981 al 2017, y la muestra esta conformada por los Estados de Situación Financiera y los Estados de Resultados del periodo 2014 al 2017. Las técnicas e instrumentos utilizados en la investigación fueron guía de análisis documental y guía de entrevista, las cuales nos sirvieron como apoyo y sustento para lograr alcanzar nuestro objetivo general. Los resultados obtenidos a través de la aplicación de los diferentes métodos de análisis utilizados, se determinó deficiencias en la empresa en sus diferentes cuentas como; resultado del ejercio, efectivo y equivalente de efectivo, cuentas por cobrar. En conclusión se llegó que las cuentas por cobrar se incrementaron en el periodo 2017 debido al lento retorno de las cobranzas y por los créditos otorgados a gobiernos regionales de Ancash y La Libertad, si bien esta cuanta es parte del activo corriente es muy importante que sea cobrado en los plazos establecidos para generar liquidez en beneficio de la empresa

Increased production of IL-4 and IL-12p40 from bronchoalveolar lavage cells are biomarkers of Mycobacterium tuberculosis in the sputum

BACKGROUND: Tuberculosis (TB) causes 1.45 million deaths annually world wide, the majority of which occur in the developing world. Active TB disease represents immune failure to control latent infection from airborne spread. Acid-fast bacillus (AFB) seen on sputum smear is a biomarker for contagiousness. METHODS: We enrolled 73 tuberculosis patients with extensive infiltrates into a research study using bronchoalveolar lavage (BAL) to sample lung immune cells and assay BAL cell cytokine production. All patients had sputum culture demonstrating Mycobacterium tuberculosis and 59/73 (81%) had AFB identified by microscopy of the sputum. Compared with smear negative patients, smear positive patients at presentation had a higher proportion with smoking history, a higher proportion with temperature >38.5 0 C, higher BAL cells/ml, lower percent lymphocytes in BAL, higher IL-4 and IL-12p40 in BAL cell supernatants. There was no correlation between AFB smear and other BAL or serum cytokines. Increasing IL-4 was associated with BAL PMN and negatively associated with BAL lymphocytes. Each 10-fold increase in BAL IL-4 and IL-12p40 increased the odds of AFB smear positivity by 7.4 and 2.2-fold, respectively, in a multi-variable logistic model. CONCLUSION: Increasing IL-4 and IL-12p40 production by BAL cells are biomarkers for AFB in sputum of patients who present with radiographically advanced TB. They likely reflect less effective immune control of pathways for controlling TB, leading to patients with increased infectiousness

Home-Based Respiratory Physiotherapy and Telephone-Based Psychological Support for COVID-19 Survivors in Peru: Protocol for a Randomized Controlled Trial.

BACKGROUND: Both pulmonary and mental health are affected following hospitalization for COVID-19 pneumonia. Pulmonary rehabilitation therapy has demonstrated benefits in improving mental health, but no validated combined programs that include mental health have been proposed. OBJECTIVE: This article presents the design of a trial that aimed to assess whether the participation in a combined rehabilitation program that includes home-based respiratory physiotherapy and telephone-based psychological support is associated with a greater improvement of pulmonary and mental health outcomes 7-12 weeks after COVID-19 hospitalization discharge compared with posthospital usual care provided by a public Peruvian hospital. METHODS: WAYRA (the word for air in the Quechua language) was an open-label, unblinded, two-arm randomized controlled trial. We recruited 108 participants aged 18-75 years who were discharged from the hospital after COVID-19 pneumonia that required >6 liters/minute of supplemental oxygen during treatment. Participants were randomly assigned at a 1:1 ratio to receive the combined rehabilitation program or usual posthospital care provided by a public Peruvian hospital. The intervention consisted of 12 at-home respiratory rehabilitation sessions and 6 telephone-based psychological sessions. The primary outcome was the 6-minute walk distance. Secondary outcomes included lung function, mental health status (depression, anxiety, and trauma), and quality of life. Outcomes were assessed at baseline (before randomization) and at 7 and 12 weeks after hospital discharge to assess the difference between arms. RESULTS: This study was funded by the Peruvian National Council of Science Technology and Technology Innovation in July 2020. Ethics approval was obtained on September 2, 2020. Recruitment and data collection occurred between October 2020 and June 2021. Results are expected to be published by the end of 2022. CONCLUSIONS: WAYRA was the first randomized controlled trial evaluating combined pulmonary-mental health rehabilitation for hospitalized COVID-19 survivors in resource-limited settings, potentially providing a foundation for the cost-effective scale-up of similar multidisciplinary rehabilitation programs. TRIAL REGISTRATION: ClinicalTrials.gov NCT04649736; https://clinicaltrials.gov/ct2/show/NCT04649736. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): RR1-10.2196/36001

Impact of Optimized Breastfeeding on the Costs of Necrotizing Enterocolitis in Extremely Low Birthweight Infants

To estimate risk of NEC for ELBW infants as a function of preterm formula and maternal milk (MM) intake and calculate the impact of suboptimal feeding on NEC incidence and costs

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

Evaluación financiera y económica del periodo 2014 al 2017 y propuesta de un plan financiero para la empresa “Agropecuaria Chimú S.R.L”, Trujillo – 2018

En el presente trabajo de investigación se ha planteado como objetivo general: Desarrolar una evaluación financiera y económica del periodo 2014 al 2017, y una propuesta de un Plan Financiero para la Empresa Agropecuaria Chimú S.R.L. Para el logro de dicho objetivo general se ha aplicado los siguientes objetivos específicos; Analizar la situación financiera y económica de los periodos 2014 al 2017, a través del método vertical y horizontal; comparar e interpretar los resultados a través de la aplicación de ratios; y por último plantear como propuesta un plan financiero que sirva como herrmamienta de apoyo para la empresa. Por otra parte la población esta conformada por los Estados de Situación Financiera y los Estados de Resultados desde el periodo 1981 al 2017, y la muestra esta conformada por los Estados de Situación Financiera y los Estados de Resultados del periodo 2014 al 2017. Las técnicas e instrumentos utilizados en la investigación fueron guía de análisis documental y guía de entrevista, las cuales nos sirvieron como apoyo y sustento para lograr alcanzar nuestro objetivo general. Los resultados obtenidos a través de la aplicación de los diferentes métodos de análisis utilizados, se determinó deficiencias en la empresa en sus diferentes cuentas como; resultado del ejercio, efectivo y equivalente de efectivo, cuentas por cobrar. En conclusión se llegó que las cuentas por cobrar se incrementaron en el periodo 2017 debido al lento retorno de las cobranzas y por los créditos otorgados a gobiernos regionales de Ancash y La Libertad, si bien esta cuanta es parte del activo corriente es muy importante que sea cobrado en los plazos establecidos para generar liquidez en beneficio de la empresa

Assessment of the occurrence of waterborne disease in relation to water consumption practices and microbial quality of common water source in Barangay San Lorenzo Ruiz I, Dasmarinas City, Cavite

As one of the basic needs, there are still people who do not have access to clean drinking water leading to high rates of different outbreaks, also affected by malpractices of water consumption. The aim of this study was to assess the occurrence of waterborne diseases in relation to water consumption practices and microbial quality of water source in Barangay San Lorenzo Ruiz I, Dasmariñas City Cavite. The social assessment of water consumption practices was done through a survey of 157 households while pH and Most Probable Number Test were used to assess the water quality. The pH level measurement had shown that the water sample had a pH of 6.8 and was within the standard range of pH 6-8 for drinking water set by WHO. As there was no production of gas in the tubes, the samples were negative wit