Abcès hypophysaire chez un hémodialysé chronique traité médicalement : à propos d’une observation

L’abcès hypophysaire est une pathologie rare et fatale en absence de traitement adéquat .Il est à évoquer devant un tableau clinique  d’hypertension intracrânienne, une dysrégulation hormonale hypophysaire et un contexte infectieux. Une conduite thérapeutique basée sur une  antibiothérapie pourrait être tenté si diagnostic précoce. Nous rapportons un cas d’abcès hypophysaire survenant chez un hémodialysé chronique pris en charge par une antibiothérapie seule dont l’évolution était favorable avec un recul de 2 ans

Zn treatment effects on biological potential of fennel bulbs as affected by in vitro digestion process

Zn treatment effects on the stability of polyphenols, MDA (malondialdehyde) content, antioxidant and lipoxygenase inhibition activities of two varieties of fennel bulbs were studied by using an in vitro gastrointestinal digestion model. Likewise, the effect of Zn on viability cells of E. coli was also performed. The results revealed that high amounts of total phenolic and flavonoid compounds were released during the digestion process, especially after the intestinal phase. Additionally, the antioxidant and lipoxygenase inhibitory activity were affected by the gastrointestinal digestion process and seems to be correlated with total phenol contents. On the other hand, the viability of E. coli was not affected by the activity of our tested bulbs during passage through the artificial digestion model, but the treated bulbs activity contribute relatively to the inhibition growth of bacteria. The survival of E. coli in fennel bulbs was challenged with simulated gastrointestinal fluids and the results showed that the E. coli strains, despite having experienced a viability reduction at the intestinal phase, were able to overcome the exposure to the gastrointestinal synthetic fluids. This E. coli ability reinforces the need for good hygienic measures to assure safe fresh produce, even for those that are rich in antibacterial compounds.info:eu-repo/semantics/publishedVersio

Forme pseudo tumorale d’une pneumopathie chronique à éosinophiles d’évolution fatale

La pneumopathie chronique idiopathique à éosinophile est une pathologie rare, de cause inconnue, caractérisée par des opacités pulmonaires périphériques, une éosinophilie périphérique >1000/mm3 et /ou une éosinophilie alvéolaire >25%. Le diagnostic est difficile à cause de la non spécificité des signes cliniques et radiologiques. Le traitement se base essentiellement sur la corticothérapie. L'évolution est généralement favorable. Nous rapportons un cas de cette entité rare dans sa forme pseudotumorale sans hyperéosinophilie, de diagnostic tardif suite à l'étude histologique de la lobectomie chirurgicale et d'évolution fatale

Léiomyosarcome de la veine cave inférieure: Un cas clinique

Le léiomyosarcome de la veine cave inférieure est une tumeur maligne rare développée aux dépens des cellules musculaires lisses de la paroi vasculaire. L'imagerie radiologique par tomodensitométrie ou résonance magnétique nucléaire est un élément important au diagnostic et au bilan d'extension tumorale. Le traitement est chirurgical. Nous illustrons l'apport de l'imagerie à travers un cas de léiomyosarcome révélé par des épigastralgies  paroxystiques, dont le diagnostique était orienté par la TDM, et confirmé par l'étude histologique. L'évolution était favorable. Après 2 ans de recul, la  patiente était indemne de toute récidive tumorale

Antioxidant activity and enzyme inhibitory potential of Euphorbia resinifera and E. officinarum honeys from Morocco and plant aqueous extracts

Natural products may be applied in a wide range of domains, from agriculture to food and pharmaceutical industries. In this study, the antioxidant properties and the capacity to inhibit some enzymatic activities ofEuphorbia resiniferaandEuphorbia officinarumaqueous extracts and honeys were assessed. The physicochemical characteristics were also evaluated. Higher amounts of iron, copper and aluminium were detected inE. officinarumhoney, which may indicate environmental pollution around the beehives or inadequate storage of honey samples. This honey sample showed higher amounts of total phenols and better capacity for scavenging superoxide anion free radicals and DPPH free radicals as compared withE. resiniferahoney, but poorer capacity for inhibiting lipoxygenase, acetylcholinesterase, tyrosinase and xanthine oxidase. The ratio plant mass:solvent volume (1:100) and extraction time (1 - 2 h) were associated with higher total phenols and better antioxidant activities and lipoxygenase, acetylcholinesterase and tyrosinase inhibitory activities, regardless of the plant species. The aqueous extracts had systematically higher in vitro activities than the respective honey samples.FCTPortuguese Foundation for Science and TechnologyEuropean Commission [UID/MAR/00350/2020]info:eu-repo/semantics/publishedVersio