Conformal symmetry and deflationary gas universe

We describe the ``deflationary'' evolution from an initial de Sitter phase to a subsequent Friedmann-Lema\^{\i}tre-Robertson-Walker (FLRW) period as a specific non-equilibrium configuration of a self-interacting gas. The transition dynamics corresponds to a conformal, timelike symmetry of an ``optical'' metric, characterized by a refraction index of the cosmic medium which continously decreases from a very large initial value to unity in the FLRW phase.Comment: 10 pages, to appear in "Exact Solutions and Scalar Fields in Gravity: Recent Developments", ed. by A. Macias, J. Cervantes-Cota, and C. L\"ammerzahl, Kluwer Academic Publishers 200

Leaf morphology in cowpea [Vigna unguiculata (L.) Walp]: QTL analysis, physical mapping and identifying a candidate gene using synteny with model legume species

Cowpea [Vigna unguiculata (L.) Walp] exhibits a considerable variation in leaf shape. Although cowpea is mostly utilized as a dry grain and animal fodder crop, cowpea leaves are also used as a high-protein pot herb in many countries of Africa

Identification of markers associated with bacterial blight resistance loci in cowpea (Vigna unguiculata (L.) Walp.)

Cowpea bacterial blight (CoBB), caused by Xanthomonas axonopodis pv. vignicola (Xav), is a worldwide major disease of cowpea [Vigna unguiculata (L.) Walp.]. Among different strategies to control the disease including cultural practices, intercropping, application of chemicals, and sowing pathogen-free seeds, planting of cowpea genotypes with resistance to the pathogen would be the most attractive option to the resource poor cowpea farmers in sub-Saharan Africa. Breeding resistance cultivars would be facilitated by marker-assisted selection (MAS). In order to identify loci with effects on resistance to this pathogen and map QTLs controlling resistance to CoBB, eleven cowpea genotypes were screened for resistance to bacterial blight using 2 virulent Xav18 and Xav19 strains isolated from Kano (Nigeria). Two cowpea genotypes Danila and Tvu7778 were identified to contrast in their responses to foliar disease expression following leaf infection with pathogen. A set of recombinant inbred lines (RILs) comprising 113 individuals derived from Danila (resistant parent) and Tvu7778 (susceptible parent) were infected with CoBB using leaf inoculation method. The experiments were conducted under greenhouse conditions (2007 and 2008) and disease severity was visually assessed using a scale where 0 = no disease and 4 = maximum susceptibility with leaf drop. A single nucleotide polymorphism (SNP) genetic map with 282 SNP markers constructed from the same RIL population was used to perform QTL analysis. Using Kruskall-Wallis and Multiple-QTL model of MapQTL 5, three QTLs, CoBB-1, CoBB-2 and CoBB-3 were identified on linkage group LG3, LG5 and LG9 respectively showing that potential resistance candidate genes cosegregated with CoBB resistance phenotypes. Two of the QTLs CoBB-1, CoBB-2 were consistently confirmed in the two experiments accounting for up to 22.1 and to 17.4% respectively for the first and second experiments. Whereas CoBB-3 was only discovered for the first experiment (2007) with less phenotypic variation explained of about 10%. Our results represent a resource for molecular marker development that can be used for marker assisted selection of bacterial blight resistance in cowpe

Stress effects in structure formation

Residual velocity dispersion in cold dark matter induces stresses which lead to effects that are absent in the idealized dust model. A previous Newtonian analysis showed how this approach can provide a theoretical foundation for the phenomenological adhesion model. We develop a relativistic kinetic theory generalization which also incorporates the anisotropic velocity dispersion that will typically be present. In addition to density perturbations, we consider the rotational and shape distortion properties of clustering. These quantities together characterize the linear development of density inhomogeneity, and we find exact solutions for their evolution. As expected, the corrections are small and arise only in the decaying modes, but their effect is interesting. One of the modes for density perturbations decays less rapidly than the standard decaying mode. The new rotational mode generates precession of the axis of rotation. The new shape modes produce additional distortion that remains frozen in during the subsequent (linear) evolution, despite the rapid decay of the terms that caused it.Comment: significantly improved discussion of kinetic theory of CDM velocity dispersion; to appear Phys. Rev.

General relativistic spinning fluids with a modified projection tensor

An energy-momentum tensor for general relativistic spinning fluids compatible with Tulczyjew-type supplementary condition is derived from the variation of a general Lagrangian with unspecified explicit form. This tensor is the sum of a term containing the Belinfante-Rosenfeld tensor and a modified perfect-fluid energy-momentum tensor in which the four-velocity is replaced by a unit four-vector in the direction of fluid momentum. The equations of motion are obtained and it is shown that they admit a Friedmann-Robertson-Walker space-time as a solution.Comment: Submitted to General Relativity and Gravitatio

Genetic architecture of delayed senescence, biomass, and grain yield under drought stress in cowpea

CowpeaThe stay-green phenomenon is a key plant trait with wide usage in managing crop production under limited water conditions. This trait enhances delayed senescence, biomass, and grain yield under drought stress. In this study we sought to identify QTLs in cowpea (Vigna unguiculata) consistent across experiments conducted in Burkina Faso, Nigeria, Senegal, and the United States of America under limited water conditions. A panel of 383 diverse cowpea accessions and a recombinant inbred line population (RIL) were SNP genotyped using an Illumina 1536 GoldenGate assay. Phenotypic data from thirteen experiments conducted across the four countries were used to identify SNP-trait associations based on linkage disequilibrium association mapping, with bi-parental QTL mapping as a complementary strategy. We identified seven loci, five of which exhibited evidence suggesting pleiotropic effects (stay-green) between delayed senescence, biomass, and grain yield. Further, we provide evidence suggesting the existence of positive pleiotropy in cowpea based on positively correlated mean phenotypic values (0.34, r ,0.87) and allele effects (0.07, r ,0.86) for delayed senescence and grain yield across three African environments. Three of the five putative stay-green QTLs, Dro-1, 3, and 7 were identified in both RILs and diverse germplasm with resolutions of 3.2 cM or less for each of the three loci, suggesting that these may be valuable targets for marker-assisted breeding in cowpea. Also, the co-location of early vegetative delayed senescence with biomass and grain yield QTLs suggests the possibility of using delayed senescence at the seedling stage as a rapid screening tool for post-flowering drought tolerance in cowpea breeding. BLAST analysis using EST sequences harboring SNPs with the highest associations provided a genomic context for loci identified in this study in closely related common bean (Phaseolus vulgaris) and soybean (Glycine max) reference genomes

Collisional equilibrium, particle production and the inflationary universe

Particle production processes in the expanding universe are described within a simple kinetic model. The equilibrium conditions for a Maxwell-Boltzmann gas with variable particle number are investigated. We find that radiation and nonrelativistic matter may be in equilibrium at the same temperature provided the matter particles are created at a rate that is half the expansion rate. Using the fact that the creation of particles is dynamically equivalent to a nonvanishing bulk pressure we calculate the backreaction of this process on the cosmological dynamics. It turns out that the `adiabatic' creation of massive particles with an equilibrium distribution for the latter necessarily implies power-law inflation. Exponential inflation in this context is shown to become inconsistent with the second law of thermodynamics after a time interval of the order of the Hubble time.Comment: 19 pages, latex, no figures, to appear in Phys.Rev.

Gene pools and the genetic architecture of domesticated cowpea

Open Access JournalCowpea [Vigna unguiculata (L.) Walp.] is a major tropical legume crop grown in warm to hot areas throughout the world and especially important to the people of sub-Saharan Africa where the crop was domesticated. To date, relatively little is understood about its domestication origins and patterns of genetic variation. In this study, a worldwide collection of cowpea landraces and African ancestral wild cowpea was genotyped with more than 1200 single nucleotide polymorphism markers. Bayesian inference revealed the presence of two major gene pools in cultivated cowpea in Africa. Landraces from gene pool 1 are mostly distributed in western Africa while the majority of gene pool 2 are located in eastern Africa. Each gene pool is most closely related to wild cowpea in the same geographic region, indicating divergent domestication processes leading to the formation of two gene pools. The total genetic variation within landraces from countries outside Africa was slightly greater than within African landraces. Accessions from Asia and Europe were more related to those from western Africa while accessions from the Americas appeared more closely related to those from eastern Africa. This delineation of cowpea germplasm into groups of genetic relatedness will be valuable for guiding introgression efforts in breeding programs and for improving the efficiency of germplasm managemen

The Physical Role of Gravitational and Gauge Degrees of Freedom in General Relativity - II: Dirac versus Bergmann observables and the Objectivity of Space-Time

(abridged)The achievements of the present work include: a) A clarification of the multiple definition given by Bergmann of the concept of {\it (Bergmann) observable. This clarification leads to the proposal of a {\it main conjecture} asserting the existence of i) special Dirac's observables which are also Bergmann's observables, ii) gauge variables that are coordinate independent (namely they behave like the tetradic scalar fields of the Newman-Penrose formalism). b) The analysis of the so-called {\it Hole} phenomenology in strict connection with the Hamiltonian treatment of the initial value problem in metric gravity for the class of Christoudoulou -Klainermann space-times, in which the temporal evolution is ruled by the {\it weak} ADM energy. It is crucial the re-interpretation of {\it active} diffeomorphisms as {\it passive and metric-dependent} dynamical symmetries of Einstein's equations, a re-interpretation which enables to disclose their (nearly unknown) connection to gauge transformations on-shell; this is expounded in the first paper (gr-qc/0403081). The use of the Bergmann-Komar {\it intrinsic pseudo-coordinates} allows to construct a {\it physical atlas} of 4-coordinate systems for the 4-dimensional {\it mathematical} manifold, in terms of the highly non-local degrees of freedom of the gravitational field (its four independent {\it Dirac observables}), and to realize the {\it physical individuation} of the points of space-time as {\it point-events} as a gauge-fixing problem, also associating a non-commutative structure to each 4-coordinate system.Comment: 41 pages, Revtex

The temporal dynamics of Arc expression regulate cognitive flexibility

YesNeuronal activity regulates the transcription and translation of the immediate-early gene Arc/Arg3.1, a key mediator of synaptic plasticity. Proteasomedependent degradation of Arc tightly limits its temporal expression, yet the significance of this regulation remains unknown. We disrupted the temporal control of Arc degradation by creating an Arc knockin mouse (ArcKR) where the predominant Arc ubiquitination sites were mutated. ArcKR mice had intact spatial learning but showed specific deficits in selecting an optimal strategy during reversal learning. This cognitive inflexibility was coupled to changes in Arc mRNA and protein expression resulting in a reduced threshold to induce mGluR-LTD and enhanced mGluR-LTD amplitude. These findings show that the abnormal persistence of Arc protein limits the dynamic range of Arc signaling pathways specifically during reversal learning. Our work illuminates how the precise temporal control of activity-dependent molecules, such as Arc, regulates synaptic plasticity and is crucial for cognition.Open access funded by Biotechnology and Biological Sciences Research Counci