Child Abuse and Its Long Term Effects

This research project examined different types and frequencies of child abuse and their relationship to depression in adulthood. The sample for our research was Valparaiso University students (ages 18-22). Our sample included various genders, education levels, and occupations. We advertised in the Valparaiso University Counseling Center, in the Social Work department, through sending emails to VU students, and through word of mouth. Participants filled out a questionnaire that included various depression and child abuse questions. Correlations were used to examine the relationships. Findings from our research have implications on the interconnections of early and later life experiences and the needs for treatment as well as what that treatment might look like. Presenters for this research project are Rachel Egan, Lauren King, and Becky Lohse, all senior Social Work majors. The Faculty Sponsor for this research project was Professor Matthew Ringenberg (PhD) from the Valparaiso University Department of Social Work

Child Abuse and Its Long Term Effects

This research project examined different types and frequencies of child abuse and their relationship to depression in adulthood. The sample for our research was Valparaiso University students (ages 18-22). Our sample included various genders, education levels, and occupations. We advertised in the Valparaiso University Counseling Center, in the Social Work department, through sending emails to VU students, and through word of mouth. Participants filled out a questionnaire that included various depression and child abuse questions. Correlations were used to examine the relationships. Findings from our research have implications on the interconnections of early and later life experiences and the needs for treatment as well as what that treatment might look like. Presenters for this research project are Rachel Egan, Lauren King, and Becky Lohse, all senior Social Work majors. The Faculty Sponsor for this research project was Professor Matthew Ringenberg (PhD) from the Valparaiso University Department of Social Work

The role of human ventral visual cortex in motion perception.

Visual motion perception is fundamental to many aspects of visual perception. Visual motion perception has long been associated with the dorsal (parietal) pathway and the involvement of the ventral 'form' (temporal) visual pathway has not been considered critical for normal motion perception. Here, we evaluated this view by examining whether circumscribed damage to ventral visual cortex impaired motion perception. The perception of motion in basic, non-form tasks (motion coherence and motion detection) and complex structure-from-motion, for a wide range of motion speeds, all centrally displayed, was assessed in five patients with a circumscribed lesion to either the right or left ventral visual pathway. Patients with a right, but not with a left, ventral visual lesion displayed widespread impairments in central motion perception even for non-form motion, for both slow and for fast speeds, and this held true independent of the integrity of areas MT/V5, V3A or parietal regions. In contrast with the traditional view in which only the dorsal visual stream is critical for motion perception, these novel findings implicate a more distributed circuit in which the integrity of the right ventral visual pathway is also necessary even for the perception of non-form motion

Art, Artifact, Archive: African American Experiences in the Nineteenth Century

Angelo Scarlato’s extraordinary and vast collection of art and artifacts related to the Civil War, and specifically to the Battle of Gettysburg, the United States Colored Troops, slavery and the African American struggle for emancipation, citizenship and freedom has proved to be an extraordinary resource for Gettysburg College students. The 2012-14 exhibition in Musselman Library’s Special Collections, curated by Lauren Roedner ’13, entitled Slaves, Soldiers, Citizens: African American Artifacts of the Civil War Era and its corresponding catalogue provided a powerful and comprehensive historical narrative of the period. This fall, students in my course at Gettysburg College “Art and Public Policy”—Diane Brennan, Maura Conley, Abigail Conner, Nicole Conte, Victoria Perez-Zetune, Savannah Rose, Kaylyn Sawyer, Caroline Wood and Zoe Yeoh—selected additional objects of material and print culture from Angelo’s private collection and drew from Lauren’s expertise for the exhibition Art, Artifact, Archive: African American Experiences in the Nineteenth Century to investigate public representations of a newly freed population as well as their more personal perspectives. [excerpt]https://cupola.gettysburg.edu/artcatalogs/1015/thumbnail.jp

University Developed Hardware for the Space Shuttle: Strategies for Success

The current trend in space science is for payload developers to minimize program cost and schedule while conducting useful science. One problem with the design, integration, and testing of lowcost missions is that much of the savings results from the assumption of risk. Analyzing lessons learned from high-risk programs is an effective means for increasing success while meeting budget and schedule constraints. University efforts, such as the University Nanosat Program (UNP), are faced with the seemingly contradictory goals of mission success and low cost while designing revolutionary experiments. Currently planned for a shuttle launch, UNP is subject to rigorous qualification requirements resulting from NASA’s manned spaceflight safety program. Universities have limited experience with the design, integration, and test of flight hardware for manned spaceflight. The program has identified many areas for improvement. This paper explores the effects of various program and technical approaches--those that worked, and those that didn’t. Design, integration and test, configuration management, quality assurance, and safety are considered. Lessons learned from the University Nanosat Program are expected to be the basis for success in launching future university-built technology

Self-Compassion and Instagram Use Is Explained by the Relation to Anxiety, Depression, and Stress

Abstract: Previous research acknowledges that prolonged social media use is associated with several negative psychological consequences, including higher levels of depression, anxiety, and stress. In order to protect individuals from social stressors, research illustrates the role that self-compassion can play, with individuals high in self-compassion reporting greater emotional wellbeing; hence, proposing self-compassion could be a trait that is positively related to social media use. This research aimed to investigate the relationship between Instagram use and self-compassion, and whether this relationship can be explained through the relation to psychological wellbeing (depression, anxiety, and stress). A cross-sectional study was conducted to investigate this relationship amongst young adults (n = 173), utilizing a revised version of The Multidimensional Facebook Intensity Scale to explore Instagram, The Self-Compassion Scale, and the Depression, Anxiety, and Stress Scale. Instagram intensity appeared to influence psychological wellbeing, with participants who spent more time on Instagram reporting poorer psychological wellbeing. Whilst higher levels of self-compassion were associated with lower levels of reported depression, anxiety, and stress, the relationship between Instagram intensity and self-compassion was not mediated to the extent as expected by wellbeing. Possible explanations and future directions are discussed as to what could explain the positive relationship between self-compassion and Instagram use

Experimental evidence of genome-wide impact of ecological selection during early stages of speciation-with-gene-flow

Theory predicts that speciation-with-gene-flow is more likely when the consequences of selection for population divergence transitions from mainly direct effects of selection acting on individual genes to a collective property of all selected genes in the genome. Thus, understanding the direct impacts of ecologically based selection, as well as the indirect effects due to correlations among loci, is critical to understanding speciation. Here, we measure the genome-wide impacts of host-associated selection between hawthorn and apple host races of Rhagoletis pomonella (Diptera: Tephritidae), a model for contemporary speciation-with-gene-flow. Allele frequency shifts of 32 455 SNPs induced in a selection experiment based on host phenology were genome wide and highly concordant with genetic divergence between co-occurring apple and hawthorn flies in nature. This striking genome-wide similarity between experimental and natural populations of R. pomonella underscores the importance of ecological selection at early stages of divergence and calls for further integration of studies of eco-evolutionary dynamics and genome divergence

GLP-1 receptor signalling promotes β-cell glucose metabolism via mTOR-dependent HIF-1α activation

Glucagon-like peptide-1 (GLP-1) promotes insulin secretion from pancreatic β-cells in a glucose dependent manner. Several pathways mediate this action by rapid, kinase phosphorylation-dependent, but gene expression-independent mechanisms. Since GLP-1-induced insulin secretion requires glucose metabolism, we aimed to address the hypothesis that GLP-1 receptor (GLP-1R) signalling can modulate glucose uptake and utilization in β-cells. We have assessed various metabolic parameters after short and long exposure of clonal BRIN-BD11 β-cells and rodent islets to the GLP-1R agonist Exendin-4 (50nM). Here we report for the first time that prolonged stimulation of the GLP-1R for 18hours promotes metabolic reprogramming of β-cells. This is evidenced by up-regulation of glycolytic enzyme expression, increased rates of glucose uptake and consumption, as well as augmented ATP content, insulin secretion and glycolytic flux after removal of Exendin-4. In our model, depletion of HypoxiaInducible Factor 1 alpha (HIF-1α) impaired the effects of Exendin-4 on glucose metabolism, while pharmacological inhibition of Phosphoinositide 3-kinase (PI3K) or mTOR completely abolished such effects. Considering the central role of glucose catabolism for stimulus-secretion coupling in β-cells, our findings suggest that chronic GLP-1 actions on insulin secretion include elevated β-cell glucose metabolism. Moreover, our data reveal novel aspects of GLP-1 stimulated insulin secretion involving de novo gene expression

Exercise training improves long-term memory in obese mice

Obesity has been linked to a range of pathologies, including dementia. In contrast, regular physical activity is associated with the prevention or reduced progression of neurodegeneration. Specifically, physical activity can improve memory and spatial cognition, reduce age-related cognitive decline, and preserve brain volume, but the mechanisms are not fully understood. Accordingly, we investigated whether any detrimental effects of high-fat diet (HFD)-induced obesity on cognition, motor behavior, adult hippocampal neurogenesis, and brain-derived neurotrophic factor (BDNF) could be mitigated by voluntary exercise training in male C57Bl/6 mice. HFD-induced impairment of motor function was not reversed by exercise. Importantly, voluntary wheel running improved long-term memory and increased hippocampal neurogenesis, suggesting that regular physical activity may prevent cognitive decline in obesity