716 research outputs found
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The Europa Ocean Discovery mission
Since it was first proposed that tidal heating of Europa by Jupiter might lead to liquid water oceans below Europa`s ice cover, there has been speculation over the possible exobiological implications of such an ocean. Liquid water is the essential ingredient for life as it is known, and the existence of a second water ocean in the Solar System would be of paramount importance for seeking the origin and existence of life beyond Earth. The authors present here a Discovery-class mission concept (Europa Ocean Discovery) to determine the existence of a liquid water ocean on Europa and to characterize Europa`s surface structure. The technical goal of the Europa Ocean Discovery mission is to study Europa with an orbiting spacecraft. This goal is challenging but entirely feasible within the Discovery envelope. There are four key challenges: entering Europan orbit, generating power, surviving long enough in the radiation environment to return valuable science, and complete the mission within the Discovery program`s launch vehicle and budget constraints. The authors will present here a viable mission that meets these challenges
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Feasibility study and design concept for an orbiting ice-penetrating radar sounder to characterize in three-dimensions the Europan ice mantle down to (and including) any ice/ocean interface
This report presents a radar sounding model based on the range of current working hypotheses for the nature of Europa's icy shell.Institute for Geophysic
Diffusion-Weighted MRI: Distinction of Skull Base Chordoma from Chondrosarcoma
BACKGROUND AND PURPOSE: Chordoma and chondrosarcoma of the skull base are rare tumors with overlapping presentations and anatomic imaging features but different prognoses. We hypothesized that these tumors might be distinguished by using diffusion-weighted MR imaging. MATERIALS AND METHODS: We retrospectively reviewed 19 patients with pathologically confirmed chordoma or chondrosarcoma who underwent both conventional and diffusion-weighted MR imaging. Differences in distributions of ADC were assessed by the Kruskal-Wallis test. Associations between histopathologic diagnosis and conventional MR imaging features (T2 signal intensity, contrast enhancement, and tumor location) were assessed with the Fisher exact test. RESULTS: Chondrosarcoma was associated with the highest mean ADC value (2051 ± 261 × 10−6 mm2/s) and was significantly different from classic chordoma (1474 ± 117 × 10−6 mm2/s) and poorly differentiated chordoma (875 ± 100 × 10−6 mm2/s) (P CONCLUSIONS: Diffusion-weighted MR imaging may be useful in assessing clival tumors, particularly in differentiating chordoma from chondrosarcoma. A prospective study of a larger cohort will be required to determine the value of ADC in predicting histopathologic diagnosis
Constraints on R-parity violating supersymmetry from leptonic and semileptonic tau, B_d and B_s decays
We put constraints on several products of R-parity violating lambda lambda'
and lambda' lambda' type couplings from leptonic and semileptonic tau, B_d and
B_s decays. Most of them are one to two orders of magnitude better than the
existing bounds, and almost free from theoretical uncertainties. A significant
improvement of these bounds can be made in high luminosity tau-charm or B
factories.Comment: 14 pages, latex. A few references added, two typos corrected. Version
to be published in Physical Review
The β3-integrin endothelial adhesome regulates microtubule-dependent cell migration
Integrin β3 is seen as a key anti-angiogenic target for cancer treatment due to its expression on neovasculature, but the role it plays in the process is complex; whether it is pro- or anti-angiogenic depends on the context in which it is expressed. To understand precisely β3's role in regulating integrin adhesion complexes in endothelial cells, we characterised, by mass spectrometry, the β3-dependent adhesome. We show that depletion of β3-integrin in this cell type leads to changes in microtubule behaviour that control cell migration. β3-integrin regulates microtubule stability in endothelial cells through Rcc2/Anxa2-driven control of active Rac1 localisation. Our findings reveal that angiogenic processes, both in vitro and in vivo, are more sensitive to microtubule targeting agents when β3-integrin levels are reduced
The Weak Charge of the Proton and New Physics
We address the physics implications of a precision determination of the weak
charge of the proton, QWP, from a parity violating elastic electron proton
scattering experiment to be performed at the Jefferson Laboratory. We present
the Standard Model (SM) expression for QWP including one-loop radiative
corrections, and discuss in detail the theoretical uncertainties and missing
higher order QCD corrections. Owing to a fortuitous cancellation, the value of
QWP is suppressed in the SM, making it a unique place to look for physics
beyond the SM. Examples include extra neutral gauge bosons, supersymmetry, and
leptoquarks. We argue that a QWP measurement will provide an important
complement to both high energy collider experiments and other low energy
electroweak measurements. The anticipated experimental precision requires the
knowledge of the order alpha_s corrections to the pure electroweak box
contributions. We compute these contributions for QWP, as well as for the weak
charges of heavy elements as determined from atomic parity violation.Comment: 22 pages of LaTeX, 5 figure
Sum rules and dualities for generalized parton distributions: is there a holographic principle?
To leading order approximation, the physical content of generalized parton
distributions (GPDs) that is accessible in deep virtual electroproduction of
photons or mesons is contained in their value on the cross-over trajectory.
This trajectory separates the t-channel and s-channel dominated GPD regions.
The underlying Lorentz covariance implies correspondence between these two
regions through their relation to GPDs on the cross-over trajectory. This point
of view leads to a family of GPD sum rules which are a quark analogue of finite
energy sum rules and it guides us to a new phenomenological GPD concept. As an
example, we discuss the constraints from the JLab/Hall A data on the dominant
u-quark GPD H. The question arises whether GPDs are governed by some kind of
holographic principle.Comment: 45 pages, 4 figures, Sect. 2 reorganized for clarity. Typos in Eq.
(20) corrected. 4 new refs. Matches published versio
Plasma Wakefield Acceleration with a Modulated Proton Bunch
The plasma wakefield amplitudes which could be achieved via the modulation of
a long proton bunch are investigated. We find that in the limit of long bunches
compared to the plasma wavelength, the strength of the accelerating fields is
directly proportional to the number of particles in the drive bunch and
inversely proportional to the square of the transverse bunch size. The scaling
laws were tested and verified in detailed simulations using parameters of
existing proton accelerators, and large electric fields were achieved, reaching
1 GV/m for LHC bunches. Energy gains for test electrons beyond 6 TeV were found
in this case.Comment: 9 pages, 7 figure
The energy dependence of angular correlations inferred from mean- fluctuation scale dependence in heavy ion collisions at the SPS and RHIC
We present the first study of the energy dependence of angular
correlations inferred from event-wise mean transverse momentum
fluctuations in heavy ion collisions. We compare our large-acceptance
measurements at CM energies $\sqrt{s_{NN}} =$ 19.6, 62.4, 130 and 200 GeV to
SPS measurements at 12.3 and 17.3 GeV. $p_t$ angular correlation structure
suggests that the principal source of $p_t$ correlations and fluctuations is
minijets (minimum-bias parton fragments). We observe a dramatic increase in
correlations and fluctuations from SPS to RHIC energies, increasing linearly
with $\ln \sqrt{s_{NN}}$ from the onset of observable jet-related
fluctuations near 10 GeV.Comment: 10 pages, 4 figure
Partonic flow and -meson production in Au+Au collisions at = 200 GeV
We present first measurements of the -meson elliptic flow
() and high statistics distributions for different
centralities from = 200 GeV Au+Au collisions at RHIC. In
minimum bias collisions the of the meson is consistent with the
trend observed for mesons. The ratio of the yields of the to those of
the as a function of transverse momentum is consistent with a model
based on the recombination of thermal quarks up to GeV/,
but disagrees at higher momenta. The nuclear modification factor () of
follows the trend observed in the mesons rather than in
baryons, supporting baryon-meson scaling. Since -mesons are
made via coalescence of seemingly thermalized quarks in central Au+Au
collisions, the observations imply hot and dense matter with partonic
collectivity has been formed at RHIC.Comment: 6 pages, 4 figures, submit to PR
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