9,047 research outputs found

    Satellite Relay Telemetry of Seismic Data in Earthquake Prediction and Control

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    The Satellite Telemetry Earthquake Monitoring Program was started to evaluate the applicability of satellite relay telemetry in the collection of seismic data from a large number of dense seismograph clusters laid out along the major fault systems of western North America. Prototype clusters utilizing phone-line telemetry were then being installed by the National Center for Earthquake Research in 3 regions along the San Andreas fault in central California; and the experience of installing and operating the clusters and in reducing and analyzing the seismic data from them was to provide the raw materials for evaluation in the satellite relay telemetry project. The principal advantages of the satellite relay system over commercial telephone or microwave systems were: (1) it could be made less prone to massive failure during a major earthquake; (2) it could be extended readily into undeveloped regions; and (3) it could provide flexible, uniform communications over large sections of major global tectonic zones. Fundamental characteristics of a communications system to cope with the large volume of raw data collected by a short-period seismograph network are discussed

    A new method for monitoring global volcanic activity

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    The ERTS Data Collection System makes it feasible for the first time to monitor the level of activity at widely separated volcanoes and to relay these data rapidly to one central office for analysis. While prediction of specific eruptions is still an evasive goal, early warning of a reawakening of quiescent volcanoes is now a distinct possibility. A prototypical global volcano surveillance system was established under the ERTS program. Instruments were installed in cooperation with local scientists on 15 volcanoes in Alaska, Hawaii, Washington, California, Iceland, Guatemala, El Salvador and Nicaragua. The sensors include 19 seismic event counters that count four different sizes of earthquakes and six biaxial borehole tiltmeters that measure ground tilt with a resolution of 1 microradian. Only seismic and tilt data are collected because these have been shown in the past to indicate most reliably the level of volcano activity at many different volcanoes. Furthermore, these parameters can be measured relatively easily with new instrumentation

    The guanine nucleotide exchange factor RIC8 regulates conidial germination through Gα proteins in Neurospora crassa.

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    Heterotrimeric G protein signaling is essential for normal hyphal growth in the filamentous fungus Neurospora crassa. We have previously demonstrated that the non-receptor guanine nucleotide exchange factor RIC8 acts upstream of the Gα proteins GNA-1 and GNA-3 to regulate hyphal extension. Here we demonstrate that regulation of hyphal extension results at least in part, from an important role in control of asexual spore (conidia) germination. Loss of GNA-3 leads to a drastic reduction in conidial germination, which is exacerbated in the absence of GNA-1. Mutation of RIC8 leads to a reduction in germination similar to that in the Δgna-1, Δgna-3 double mutant, suggesting that RIC8 regulates conidial germination through both GNA-1 and GNA-3. Support for a more significant role for GNA-3 is indicated by the observation that expression of a GTPase-deficient, constitutively active gna-3 allele in the Δric8 mutant leads to a significant increase in conidial germination. Localization of the three Gα proteins during conidial germination was probed through analysis of cells expressing fluorescently tagged proteins. Functional TagRFP fusions of each of the three Gα subunits were constructed through insertion of TagRFP in a conserved loop region of the Gα subunits. The results demonstrated that GNA-1 localizes to the plasma membrane and vacuoles, and also to septa throughout conidial germination. GNA-2 and GNA-3 localize to both the plasma membrane and vacuoles during early germination, but are then found in intracellular vacuoles later during hyphal outgrowth

    Can the British Heart Foundation PocketCPR Application Improve the Performance of Chest Compressions During Bystander Resuscitation: a Randomised Crossover Manikin Study

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    This study aims to determine whether the British Heart Foundation (BHF) PocketCPR application can improve the depth and rate of chest compression, and therefore be confidently recommended for bystander use. 118 candidates were recruited into a randomised crossover manikin trial. Each candidate performed CPR for two-minutes without instruction, or performed chest compressions using the PocketCPR application. Candidates then performed a further two minutes of CPR within the opposite arm. The number of chest compressions performed improved when PocketCPR was used compared to chest compressions when it was not (44.28% v40.57, P<0.001). The number of chest compressions performed to the required depth was higher in the PocketCPR group (90.86 v 66.26). The BHF PocketCPR application improved the percentage of chest compressions that were performed to the required depth. Despite this, more work is required in order to develop a feedback device that can improve bystander CPR without creating delay

    Polarized micro-Raman studies of femtosecond laser written stress-induced optical waveguides in diamond

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    Understanding the physical mechanisms of the refractive index modulation induced by femtosecond laser writing is crucial for tailoring the properties of the resulting optical waveguides. In this work we apply polarized Raman spectroscopy to study the origin of stress-induced waveguides in diamond, produced by femtosecond laser writing. The change in the refractive index induced by the femtosecond laser in the crystal is derived from the measured stress in the waveguides. The results help to explain the waveguide polarization sensitive guiding mechanism, as well as providing a technique for their optimization.Comment: 5 pages, 4 figure

    Optimal timing of HIV home-based counselling and testing rounds in Western Kenya

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    Introduction: Weaknesses in care programmes providing anti‐retroviral therapy (ART) persist and are often instigated by late HIV diagnosis and poor linkage to care. We investigated the potential for a home‐based counselling and testing (HBCT) campaign to be improved through the optimal timing and enhancement of testing rounds to generate greater health outcomes at minimum cost. Methods: Using a mathematical model of HIV care calibrated to longitudinal data from The Academic Model Providing Access To Healthcare (AMPATH) in Kenya, we simulated HBCT campaigns between 2016 and 2036, assessing the impact and total cost of care for each, for a further 20 years. Results: We find that simulating five equally spaced rounds averts 1.53 million disability‐adjusted life‐years (DALYs) at a cost of 1617million.ByalteringthetimingofHBCTrounds,afour‐roundcampaigncanproducegreaterimpactforlowercost.With“front‐loaded”rounds,thecostperDALYavertedisreducedby121617 million. By altering the timing of HBCT rounds, a four‐round campaign can produce greater impact for lower cost. With “front‐loaded” rounds, the cost per DALY averted is reduced by 12% as fewer rounds are required (937 vs. 1060).Furthermore,improvementstoHBCTcoverageandlinkagetocareavertovertwomillionDALYsatacostperDALYavertedof1060). Furthermore, improvements to HBCT coverage and linkage to care avert over two million DALYs at a cost per DALY averted of 621 (41% less than the reference scenario). Conclusions: Countries implementing HBCT can reduce costs by optimally timing rounds and generate greater health outcomes through improving linkage, coverage, and retention. Tailoring HBCT campaigns to individual settings can enhance patient outcomes for minimal cost

    Numerical simulations of mixed states quantum computation

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    We describe quantum-octave package of functions useful for simulations of quantum algorithms and protocols. Presented package allows to perform simulations with mixed states. We present numerical implementation of important quantum mechanical operations - partial trace and partial transpose. Those operations are used as building blocks of algorithms for analysis of entanglement and quantum error correction codes. Simulation of Shor's algorithm is presented as an example of package capabilities.Comment: 6 pages, 4 figures, presented at Foundations of Quantum Information, 16th-19th April 2004, Camerino, Ital
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