Effect of a collector bag for measurement of postpartum blood loss after vaginal delivery: cluster randomised trial in 13 European countries

Objective To evaluate the effectiveness of the systematic use of a transparent plastic collector bag to measure postpartum blood loss after vaginal delivery in reducing the incidence of severe postpartum haemorrhage

Policies for manual removal of placenta at vaginal delivery: variations in timing within Europe

The length of the third stage of labour is a potential modifiable risk factor for postpartum haemorrhage at vaginal delivery, but there is no definitive evidence that early intervention to remove the placenta manually will prevent postpartum haemorrhage. We report a wide variation between countries in Europe in policies about the timing of manual removal of placenta. Two groups of countries with clearly divergent policies were identified. A randomised controlled trial is needed to provide definitive evidence on the risks and benefits of manual removal of placenta at different timings after vaginal deliveryFLWINinfo:eu-repo/semantics/publishe

Associations of drugs routinely given in labour with breastfeeding at 48 hours: analysis of the Cardiff Births Survey

Background  Little is known about how breastfeeding rates are affected by drugs routinely administered in labour. Objective  To examine a large obstetric data set to investigate potentially modifiable associations between drugs routinely administered in labour and breastfeeding in healthy women and infants. Design  Retrospective cohort. Setting The Cardiff (Wales UK) Births Survey. Population  A total of 48 366 healthy women delivering healthy singleton babies at term. Methods  Analysis of the Cardiff Births Survey. Main outcome measure  Association between intrapartum medications and breastfeeding at 48 hours postpartum. Results  At 48 hours, 43.3% (20 933/48 366) women were not breastfeeding. Regression analysis confirmed previously reported associations of lower breastfeeding rates with certain demographic indicators, epidural analgesia, intramuscular opioid analgesia and ergometrine. Novel associations were detected with oxytocin alone or in combination with ergometrine administered for prevention of postpartum haemorrhage (PPH), which were associated with reductions of 6–8%, (intramuscular oxytocin OR 0.75, 95% CI 0.61–0.91, intravenous oxytocin OR 0.68, 95% CI 0.57–0.82, oxytocin/ergometrine OR 0.77, 95% CI 0.65–0.91), and prostaglandins administered for induction of labour. The associations were maintained when subgroups, such as primiparous women, women whose labours were neither induced nor augmented, and women not receiving epidural analgesia were considered. Conclusion  Prospective studies on drugs in labour are needed to investigate potential causative associations between intrapartum medications and breastfeeding. Such studies will delineate the optimum balance between breastfeeding and maternal health, most importantly the risk of PPH