28 research outputs found
Artemether–lumefantrine treatment failure despite adequate lumefantrine day 7 concentration in a traveller with <it>Plasmodium falciparum</it> malaria after returning from Tanzania
<p>Abstract</p> <p>Artemether-lumefantrine is currently first-line therapy of <it>Plasmodium falciparum</it> malaria in many countries. This report describes a treatment failure despite adequate drug concentrations in a traveller returning from sub-Saharan Africa. Genotyping confirmed recrudescence and suggested reduced sensitivity. Potential sub-optimal effect of artemether-lumefantrine highlights the need to follow non-immune individuals the weeks after treatment.</p
The novel component Kgd4 recruits the E3 subunit to the mitochondrial α-ketoglutarate dehydrogenase
(In)Efficient Environmental Policy with Interacting Pollutants
Climate change, Cost-benefit analysis, Eutrophication, Multiple pollutants, Optimal environmental policy, Pollution control,