91 research outputs found
Bayesian Methods for Exoplanet Science
Exoplanet research is carried out at the limits of the capabilities of
current telescopes and instruments. The studied signals are weak, and often
embedded in complex systematics from instrumental, telluric, and astrophysical
sources. Combining repeated observations of periodic events, simultaneous
observations with multiple telescopes, different observation techniques, and
existing information from theory and prior research can help to disentangle the
systematics from the planetary signals, and offers synergistic advantages over
analysing observations separately. Bayesian inference provides a
self-consistent statistical framework that addresses both the necessity for
complex systematics models, and the need to combine prior information and
heterogeneous observations. This chapter offers a brief introduction to
Bayesian inference in the context of exoplanet research, with focus on time
series analysis, and finishes with an overview of a set of freely available
programming libraries.Comment: Invited revie
Quantum State Engineering and Precision Metrology using State-Insensitive Light Traps
Precision metrology and quantum measurement often demand matter be prepared
in well defined quantum states for both internal and external degrees of
freedom. Laser-cooled neutral atoms localized in a deeply confining optical
potential satisfy this requirement. With an appropriate choice of wavelength
and polarization for the optical trap, two electronic states of an atom can
experience the same trapping potential, permitting coherent control of
electronic transitions independent of the atomic center-of-mass motion. We
review a number of recent experiments that use this approach to investigate
precision quantum metrology for optical atomic clocks and coherent control of
optical interactions of single atoms and photons within the context of cavity
quantum electrodynamics. We also provide a brief survey of promising prospects
for future work.Comment: 23 pages of main text, 4 figures, and 12 pages of Supporting Online
Material (SOM
Inference of the infection status of individuals using longitudinal testing data from cryptic populations: Towards a probabilistic approach to diagnosis
Effective control of many diseases requires the accurate detection of infected individuals. Confidently ascertaining whether an individual is infected can be challenging when diagnostic tests are imperfect and when some individuals go for long periods of time without being observed or sampled. Here, we use a multi-event capture-recapture approach to model imperfect observations of true epidemiological states. We describe a method for interpreting potentially disparate results from individuals sampled multiple times over an extended period, using empirical data from a wild badger population naturally infected with Mycobacterium bovis as an example. We examine the effect of sex, capture history and current and historical diagnostic test results on the probability of being truly infected, given any combination of diagnostic test results. In doing so, we move diagnosis away from the traditional binary classification of apparently infected versus uninfected to a probability-based interpretation which is updated each time an individual is re-sampled. Our findings identified temporal variation in infection status and suggest that capture probability is influenced by year, season and infection status. This novel approach to combining ecological and epidemiological data may aid disease management decision-making by providing a framework for the integration of multiple diagnostic test data with other information
CspC regulates the expression of the glyoxylate cycle genes at stationary phase in Caulobacter
Insights into pathogenic events of HIV-associated Kaposi sarcoma and immune reconstitution syndrome related Kaposi sarcoma
A decrease in the incidence of human immune deficiency virus-associated Kaposi sarcoma (HIV-KS) and regression of some established HIV-KS lesions is evident after the introduction of highly active anti-retroviral treatment (HAART), and is attributed to generalized immune restoration, to the reconstitution of human herpesvirus (HHV)-8 specific cellular immune responses, and to the decrease in HIV Tat protein and HHV-8 loads following HAART. However, a small subset of HIV-seropositive subjects with a low CD4+ T cell count at the time of introduction of HAART, may develop HIV-KS as immune reconstitution inflammatory syndrome (IRIS) within 8 weeks thereafter
Special cases : moons, rings, comets, trojans
Non-planetary bodies provide valuable insight into our current under-
standing of planetary formation and evolution. Although these objects are
challeng- ing to detect and characterize, the potential information to be drawn
from them has motivated various searches through a number of techniques. Here,
we briefly review the current status in the search of moons, rings, comets, and
trojans in exoplanet systems and suggest what future discoveries may occur in
the near future.Comment: Invited review (status August 2017
Lawson criterion for ignition exceeded in an inertial fusion experiment
For more than half a century, researchers around the world have been engaged in attempts to achieve fusion ignition as a proof of principle of various fusion concepts. Following the Lawson criterion, an ignited plasma is one where the fusion heating power is high enough to overcome all the physical processes that cool the fusion plasma, creating a positive thermodynamic feedback loop with rapidly increasing temperature. In inertially confined fusion, ignition is a state where the fusion plasma can begin "burn propagation" into surrounding cold fuel, enabling the possibility of high energy gain. While "scientific breakeven" (i.e., unity target gain) has not yet been achieved (here target gain is 0.72, 1.37 MJ of fusion for 1.92 MJ of laser energy), this Letter reports the first controlled fusion experiment, using laser indirect drive, on the National Ignition Facility to produce capsule gain (here 5.8) and reach ignition by nine different formulations of the Lawson criterion
State of the Field: Extreme Precision Radial Velocities
The Second Workshop on Extreme Precision Radial Velocities defined circa 2015
the state of the art Doppler precision and identified the critical path
challenges for reaching 10 cm/s measurement precision. The presentations and
discussion of key issues for instrumentation and data analysis and the workshop
recommendations for achieving this precision are summarized here.
Beginning with the HARPS spectrograph, technological advances for precision
radial velocity measurements have focused on building extremely stable
instruments. To reach still higher precision, future spectrometers will need to
produce even higher fidelity spectra. This should be possible with improved
environmental control, greater stability in the illumination of the
spectrometer optics, better detectors, more precise wavelength calibration, and
broader bandwidth spectra. Key data analysis challenges for the precision
radial velocity community include distinguishing center of mass Keplerian
motion from photospheric velocities, and the proper treatment of telluric
contamination. Success here is coupled to the instrument design, but also
requires the implementation of robust statistical and modeling techniques.
Center of mass velocities produce Doppler shifts that affect every line
identically, while photospheric velocities produce line profile asymmetries
with wavelength and temporal dependencies that are different from Keplerian
signals.
Exoplanets are an important subfield of astronomy and there has been an
impressive rate of discovery over the past two decades. Higher precision radial
velocity measurements are required to serve as a discovery technique for
potentially habitable worlds and to characterize detections from transit
missions. The future of exoplanet science has very different trajectories
depending on the precision that can ultimately be achieved with Doppler
measurements.Comment: 45 pages, 23 Figures, workshop summary proceeding
Measurement of J/ψ -pair production in pp collisions at √s = 13 TeV and study of gluon transverse-momentum dependent PDFs
The production cross-section of J/ψ pairs in proton-proton collisions at a centre-of-mass energy of √s = 13 TeV is measured using a data sample corresponding to an integrated luminosity of 4.2 fb−1 collected by the LHCb experiment. The measurement is performed with both J/ψ mesons in the transverse momentum range 0 < pT< 14 GeV/c and rapidity range 2.0 < y < 4.5. The cross-section of this process is measured to be 16.36 ± 0.28 (stat) ± 0.88 (syst) nb. The contributions from single-parton scattering and double-parton scattering are separated based on the dependence of the cross-section on the absolute rapidity difference ∆y between the two J/ψ mesons. The effective cross-section of double-parton scattering is measured to be σeff = 13.1 ± 1.8 (stat) ± 2.3 (syst) mb. The distribution of the azimuthal angle ϕCS of one of the J/ψ mesons in the Collins-Soper frame and the pT-spectrum of the J/ψ pairs are also measured for the study of the gluon transverse-momentum dependent distributions inside protons. The extracted values of ⟨cos 2ϕCS⟩ and ⟨cos 4ϕCS⟩ are consistent with zero, but the presence of azimuthal asymmetry at a few percent level is allowed
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