Long-range Angular Correlations On The Near And Away Side In P-pb Collisions At √snn=5.02 Tev

7191/Mar294

Right ventricular assessment can improve prognostic value of Euroscore II

Background: The aim of this multicenter prospective study was to evaluate the prognostic weight of preoperative right ventricular assessment on early mortality in cardiac surgery. Methods: This is a multicenter prospective observational study performed by the Italian Group of Research for Outcome in Cardiac Surgery (GIROC) including 11 centers. From October 2017 to March 2019, out of 923 patients undergoing cardiac surgery, 28 patients with some missing data were excluded and 895 patients were enrolled in the study right ventricular dilatation was defined as a basal end-diastolic diameter >42 mm. The right ventricle (RV) function was assessed using the combination of three parameters: fractional area changing (FAC), tricuspid annular plane systolic excursion (TAPSE), and S'-wave using tissue Doppler imaging (TDI-S'); RV dysfunction was defined as the presence of at least two of the following cutoffs: FAC <35%, TAPSE <17 mm, and TDI S' <9.5 mm. Results: Among the entire cohort, 624 (70%) showed normal RV, 92 (10%) isolated RV dilatation, 154 (17%) isolated RV dysfunction, and 25 (3%) both RV dilatation and dysfunction. Non-surviving patients showed a significantly higher rate of RV alteration at multivariable analysis, RV status was found to be an independent predictor for higher in-hospital mortality beside Euroscore II. Conclusions: This prospective multicenter observation study shows the importance to assess RV preoperatively and to include both RV function and dimension in a risk score model such as Euroscore II to implement its predictivity, since PH cannot always mirror the status of the right ventricle

Right ventricular assessment can improve prognostic value of Euroscore II

Background The aim of this multicenter prospective study was to evaluate the prognostic weight of preoperative right ventricular assessment on early mortality in cardiac surgery.Methods This is a multicenter prospective observational study performed by the Italian Group of Research for Outcome in Cardiac Surgery (GIROC) including 11 centers. From October 2017 to March 2019, out of 923 patients undergoing cardiac surgery, 28 patients with some missing data were excluded and 895 patients were enrolled in the study right ventricular dilatation was defined as a basal end-diastolic diameter >42 mm. The right ventricle (RV) function was assessed using the combination of three parameters: fractional area changing (FAC), tricuspid annular plane systolic excursion (TAPSE), and S'-wave using tissue Doppler imaging (TDI-S'); RV dysfunction was defined as the presence of at least two of the following cutoffs: FAC <35%, TAPSE <17 mm, and TDI S' Among the entire cohort, 624 (70%) showed normal RV, 92 (10%) isolated RV dilatation, 154 (17%) isolated RV dysfunction, and 25 (3%) both RV dilatation and dysfunction. Non-surviving patients showed a significantly higher rate of RV alteration at multivariable analysis, RV status was found to be an independent predictor for higher in-hospital mortality beside Euroscore II.Conclusions This prospective multicenter observation study shows the importance to assess RV preoperatively and to include both RV function and dimension in a risk score model such as Euroscore II to implement its predictivity, since PH cannot always mirror the status of the right ventricle

Prognostic value of SARS-CoV-2 on patients undergoing cardiac surgery

Objective To analyze Italian Cardiac Surgery experience during the pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) identifying risk factors for overall mortality according to coronavirus disease 2019 (COVID-19) status. Methods From February 20 to May 31, 2020, 1354 consecutive adult patients underwent cardiac surgery at 22 Italian Centers; 589 (43.5%), patients came from the red zone. Based on COVID-19 status, 1306 (96.5%) were negative to SARS-CoV-2 (COVID-N), and 48 (3.5%) were positive to SARS-CoV-2 (COVID-P); among the COVID-P 11 (22.9%) and 37 (77.1%) become positive, before and after surgery, respectively. Surgical procedures were as follows: 396 (29.2%) isolated coronary artery bypass grafting (CABG), 714 (52.7%) isolated non-CABG procedures, 207 (15.3%) two associate procedures, and three or more procedures in 37 (2.7%). Heart failure was significantly predominant in group COVID-N (10.4% vs. 2.5%, p = .01). Results Overall in-hospital mortality was 1.6% (22 cases), being significantly higher in COVID-P group (10 cases, 20.8% vs. 12, 0.9%, p &lt; .001). Multivariable analysis identified COVID-P condition as a predictor of in-hospital mortality together with emergency status. In the COVID-P subgroup, the multivariable analysis identified increasing age and low oxygen saturation at admission as risk factors for in-hospital mortality. Conclusion As expected, SARS-CoV-2 infection, either before or soon after cardiac surgery significantly increases in-hospital mortality. Moreover, among COVID-19-positive patients, older age and poor oxygenation upon admission seem to be associated with worse outcomes

Characterizing the population of pulsars in the inner Galaxy with the Fermi Large Area Telescope

An excess of $\gamma$-ray emission from the Galactic Center (GC) region with respect to predictions based on a variety of interstellar emission models and $\gamma$-ray source catalogs has been found by many groups using data from the {\it Fermi} Large Area Telescope (LAT). Several interpretations of this excess have been invoked. In this paper we search for members of an unresolved population of $\gamma$-ray pulsars located in the inner Galaxy that are predicted by the interpretation of the GC excess as being due to a population of such sources. We use cataloged LAT sources to derive criteria that efficiently select pulsars with very small contamination from blazars. We search for point sources in the inner $40^\circ\times40^\circ$ region of the Galaxy, derive a list of approximately 400 sources, and apply pulsar selection criteria to extract pulsar candidates among our source list. We performed the entire data analysis chain with two different interstellar emission models (IEMs), and found a total of 135 pulsar candidates, of which 66 were selected with both IEMs

Characterizing the population of pulsars in the inner Galaxy with the Fermi Large Area Telescope

An excess of $\gamma$-ray emission from the Galactic Center (GC) region with respect to predictions based on a variety of interstellar emission models and $\gamma$-ray source catalogs has been found by many groups using data from the {\it Fermi} Large Area Telescope (LAT). Several interpretations of this excess have been invoked. In this paper we search for members of an unresolved population of $\gamma$-ray pulsars located in the inner Galaxy that are predicted by the interpretation of the GC excess as being due to a population of such sources. We use cataloged LAT sources to derive criteria that efficiently select pulsars with very small contamination from blazars. We search for point sources in the inner $40^\circ\times40^\circ$ region of the Galaxy, derive a list of approximately 400 sources, and apply pulsar selection criteria to extract pulsar candidates among our source list. We performed the entire data analysis chain with two different interstellar emission models (IEMs), and found a total of 135 pulsar candidates, of which 66 were selected with both IEMs