Sensomotor integration features in skilled female boxers

The paper considers features of sensomotor integration of visuomotor reactions in female boxers. It is found that sportswomen have quicker reactions, but make more mistakes in complex choice reaction. Sensomotor integration of sensomotor reaction into functional systems of activity in female boxers is also associated more with accuracy of responsive actions than in reaction rate. © JPES

EFFECT OF CERULOPLASMIN THE QUANTITATIVE COMPOSITION AND FUNCTIONAL ACTIVITY OF LEUKOCYTES IN ACUTE PHYSICAL LOAD SUBMAXIMAL POWER

In experiments on animals have shown that the use of ceruloplasmin in acute submaximal exercise capacity leads to an increase in neutrophilic leukocytes pool with a change in their functional activity. Increased ability to form aggregates of leukocyte, decrease in chemotaxis. Phagocytic function changes ambiguously — activity of phagocytosis increases, and the intensity decreases

CASCADE AN ACYLATION/INTRAMOLECULAR OXO-DIELS–ALDER (IMODA) REACTION FOR THE DIASTEREOSELECTIVE SYNTHESIS OF THIENYL SUBSTITUTED PYRANO[3,4-C]PYRROLE DERIVATIVES

This work was supported by the Russian Science Foundation (RSF) (project № 22-23-00179)

Modeling of genetic processes underlying the development of resistance to fipronil in the Colorado potato beetle (Leptinotarsa decemlineata Say)

The main method of pest control is by applying chemical insecticides. The efficacy of insecticides is reduced due to the development of resistance by pest populations. This is an especially important problem with the Colorado potato beetle. There are different strategies for the use of insecticides to slow the development of resistance. Based on long lasing research, we propose a hypothesis about delaying the development of resistance by applying insecticides at low doses. To test this hypothesis, we have built predictive discrete genetic models of resistance in Colorado potato beetle populations. The model based on the classical equations of population genetics has been supplemented by various factors. Calculations of the survival rates of Colorado potato beetle individuals were carried out taking into account the statistical regularities of the distribution of the toxic substance after treatment by insecticides. We have calculated the survival rates of different genotypes using a lognormal distribution after changing the insecticide dose two-fold or more. The factor of differentiated mortality during the winter was additionally introduced into the model. The use of phenetic markers of nonspecific resistance to environmental factors allowed us to compute the model with mediated intergenic interactions. Various hypotheses about strategies in overcoming resistance have been tested using this model. Calculations demonstrated that the use of insecticides at minimum effective doses (low dose) leads to a slower increase in the proportion of resistant individuals in populations of the Colorado potato beetle for two seasons. Resistance develops much more slowly following alternate treatment with insecticides from different chemical classes. The best strategy is through off-season treatment with insecticides of different chemical classes at lower doses

mRNA expression profile of mouse oligodendrocytes in inflammatory conditions

© 2016, Pleiades Publishing, Ltd.In this study, we performed transcriptome profiling of oligodendrocyte culture of mice treated with the remyelinating therapeutic agent benztropine in the presence and absence of interferon gamma (IFNγ). The results of this work are important for understanding the expression profile of oligodendrocytes under conditions of systemic inflammation in the central nervous system in multiple sclerosis as well as the mechanisms of cellular response to benztropine in light of its possible use for the treatment of multiple sclerosis

Nova light curves from the Solar Mass Ejection Imager (SMEI) - II. The extended catalogue

We present the results from observing nine Galactic novae in eruption with the Solar Mass Ejection Imager (SMEI) between 2004 and 2009. While many of these novae reached peak magnitudes that were either at or approaching the detection limits of SMEI, we were still able to produce light curves that in many cases contained more data at and around the initial rise, peak, and decline than those found in other variable star catalogs. For each nova, we obtained a peak time, maximum magnitude, and for several an estimate of the decline time (t2). Interestingly, although of lower quality than those found in Hounsell et al. (2010a), two of the light curves may indicate the presence of a pre-maximum halt. In addition the high cadence of the SMEI instrument has allowed the detection of low amplitude variations in at least one of the nova light curves

No Neon, but Jets in the Remarkable Recurrent Nova M31N 2008-12a?—Hubble Space Telescope Spectroscopy of the 2015 Eruption

The 2008 discovery of an eruption of M31N 2008-12a began a journey on which the true nature of this remarkable recurrent nova continues to be revealed. M31N 2008-12a contains a white dwarf (WD) close to the Chandrasekhar limit, accreting at a high rate from its companion, and undergoes thermonuclear eruptions that are observed yearly and may even be twice as frequent. In this paper, we report on Hubble Space Telescope Space Telescope Imaging Spectrograph ultraviolet spectroscopy taken within days of the predicted 2015 eruption, coupled with Keck spectroscopy of the 2013 eruption. Together, this spectroscopy permits the reddening to be constrained to E(B-V)=0.10+/- 0.03. The UV spectroscopy reveals evidence for highly ionized, structured, and high-velocity ejecta at early times. No evidence for neon is seen in these spectra, however, but it may be that little insight can be gained regarding the composition of the WD (CO versus ONe)

mRNA expression profile of mouse oligodendrocytes in inflammatory conditions

© 2016, Pleiades Publishing, Ltd.In this study, we performed transcriptome profiling of oligodendrocyte culture of mice treated with the remyelinating therapeutic agent benztropine in the presence and absence of interferon gamma (IFNγ). The results of this work are important for understanding the expression profile of oligodendrocytes under conditions of systemic inflammation in the central nervous system in multiple sclerosis as well as the mechanisms of cellular response to benztropine in light of its possible use for the treatment of multiple sclerosis

mRNA expression profile of mouse oligodendrocytes in inflammatory conditions

© 2016, Pleiades Publishing, Ltd.In this study, we performed transcriptome profiling of oligodendrocyte culture of mice treated with the remyelinating therapeutic agent benztropine in the presence and absence of interferon gamma (IFNγ). The results of this work are important for understanding the expression profile of oligodendrocytes under conditions of systemic inflammation in the central nervous system in multiple sclerosis as well as the mechanisms of cellular response to benztropine in light of its possible use for the treatment of multiple sclerosis

mRNA expression profile of mouse oligodendrocytes in inflammatory conditions

© 2016, Pleiades Publishing, Ltd.In this study, we performed transcriptome profiling of oligodendrocyte culture of mice treated with the remyelinating therapeutic agent benztropine in the presence and absence of interferon gamma (IFNγ). The results of this work are important for understanding the expression profile of oligodendrocytes under conditions of systemic inflammation in the central nervous system in multiple sclerosis as well as the mechanisms of cellular response to benztropine in light of its possible use for the treatment of multiple sclerosis