MICROSCOPIC CHANGES IN DIFFERENT ORGANS DOGS FOR THE PNEUMONIC FORM OF PLAGUE CARNIVOROUS

Чума... Мало хто з власників собак не переживає неприємних відчуттів при одному цьому слові. Чума собак відома в Європі з другої половини XVIII століття. Це одна з найбільш частих і згубних хвороб м'ясоїдних.В роботі авторами описані деякі мікроскопічні зміни в різних органах собак за легеневої форми чуми м’ясоїдних. Дослідження проводились на базі кафедри патологічної анатомії НУБіП України, куди доставляли на розтин трупи загиблих від чуми собак з різних клінік м. Києва та Київської області.При проведенні мікроскопічних досліджень було встановлено, що зміни за легеневої форми чуми собак включають вогнища геморагічної пневмонії, а також вогнища набряку в легенях, серозно-геморагічне запалення підщелепових, заглоткових, поверхневих шийних, бронхіальних та середостінних лімфовузлів, геморагічні інфаркти в селезінці, серозно-десквамативний гломерулонефрит, зернисту дистрофію гепатоцитів і кардіоміоцитів, набряк речовини мозку, а також зернисту дистрофію, пікноз ядер і руйнування цитоплазми нервових клітин.Чума... Мало кто из владельцев собак не испытывает неприятных ощущений при одном этом слове. Чума собак известна в Европе со второй половины XVIII века. Эта одна из наиболее частых и губительных болезней плотоядных.В работе авторами описаны некоторые микроскопические изменения в различных органах собак при легочной форме чумы плотоядных. Исследования проводились на базе кафедры патологической анатомии НУБиП Украины, куда доставляли на вскрытие трупы погибших от чумы собак из разных клиник Киева и Киевской области.При проведении микроскопических исследований было установлено, что изменения при легочной форме чумы собак включают очаги геморрагической пневмонии, а также очаги отека в легких, серозно-геморрагическое воспаление подчелюстных, заглоточных, поверхностных шейных, бронхиальных и средостенных лимфоузлов, геморрагические инфаркты в селезенке, серозно-десквамативный гломерулонефрит, зернистую дистрофию гепатоцитов и кардиомиоцитов, отек вещества мозга, а также зернистую дистрофию, пикноз ядер и разрушение цитоплазмы нервных клеток.Plague... Few dog owners do not feel discomfort at this one word. Plague Dogs known in Europe since the second half of the XVIII century. This is one of the most common and devastating diseases carnivores.The author describes some microscopic changes in various organs of dogs for pneumonic plague carnivores. Research conducted at the Department of Pathological Anatomy NUBiP Ukraine, which brought in autopsies of dead from the plague dogs with various hospitals in Kyiv and Kyiv region.In conducting microscopic studies found that changes for pneumonic plague dogs include hemorrhagic foci of pneumonia and lung edema fire, sero-hemorrhagic inflammation submaxillary, retropharyngeal, superficial cervical, bronchial and mediastinal lymph nodes, hemorrhagic infarcts in the spleen, sero-deskvamatiс glomerulonephritis, granular degeneration of hepatocytes and cardiomyocytes, swelling of the brain substance and granular dystrophy, piknoz nuclei and cytoplasm destruction of nerve cells

Seasonal and interannual variability of the water exchange in the Turkish Straits System estimated by modelling

A chain of simple linked models is used to simulate the seasonal and interannual variability of the Turkish Straits System. This chain includes two-layer hydraulic models of the Bosphorus and Dardanelles straits simulating the exchange in terms of level and density difference along each strait, and a one-dimensional area averaged layered model of the Marmara Sea. The chain of models is complemented also by the similar layered model of the Black Sea proper and by a one-layer Azov Sea model with the Kerch Strait. This linked chain of models is used to study the seasonal and interannual variability of the system in the period 1970-2009. The salinity of the Black Sea water flowing into the Aegean Sea increases by approximately 1.7 times through entrainment from the lower layer. The flow entering into the lower layer of the Dardanelles Strait from the Aegean Sea is reduced by nearly 80% when it reaches the Black Sea. In the seasonal scale, a maximal transport in the upper layer and minimal transport in the bottom layer are during winter/spring for the Bosphorus and in spring for the Dardanelles Strait, whereas minimal transport in upper layer and maximal undercurrent are during the summer for the Bosphorus Strait and autumn for the Dardanelles Strait. The increase of freshwater flux into the Black Sea in interannual time scales (41 m3s-1 per year) is accompanied by a more than twofold growth of the Dardanelles outflow to the North Aegean (102 m3s-1 per year)

Sensitive imaging of electromagnetic fields with paramagnetic polar molecules

We propose a method for sensitive parallel detection of low-frequency electromagnetic fields based on the fine structure interactions in paramagnetic polar molecules. Compared to the recently implemented scheme employing ultracold $^{87}$Rb atoms [B{\"o}hi \textit{et al.}, Appl. Phys. Lett. \textbf{97}, 051101 (2010)], the technique based on molecules offers a 100-fold higher sensitivity, the possibility to measure both the electric and magnetic field components, and a probe of a wide range of frequencies from the dc limit to the THz regime

SOCIALIZATION OF DIGITAL EDUCATION THROUGH THE ENHANCEMENT OF REMOTE TESTING

The article is based on the results of analysis of educational subjects for bachelors of the 1st, 2nd, and 3d years of education in the socio-adapted system of remote training for various management and economic specialization profiles. According to the conducted study, the course units have been determined for which remote training and controlled assessment are justified, the results of electronic testing of students have been summarized, the dynamics of the results has been revealed, the directions of enhancement of testing and testing material development technologies have been shown, the socio-adapted types of test questions have been highlighted, and examples of typical test questions have been provided, recommendations on the method of presentation of educational material have been formulated

Rotational coherence spectroscopy of molecules in helium nanodroplets: Reconciling the time and the frequency domains

Alignment of OCS, CS$_2$ and I$_2$ molecules embedded in helium nanodroplets is measured as a function of time following rotational excitation by a non-resonant, comparatively weak ps laser pulse. The distinct peaks in the power spectra, obtained by Fourier analysis, are used to determine the rotational, B, and centrifugal distortion, D, constants. For OCS, B and D match the values known from IR spectroscopy. For CS$_2$ and I$_2$, they are the first experimental results reported. The alignment dynamics calculated from the gas-phase rotational Schr\"{o}dinger equation, using the experimental in-droplet B and D values, agree in detail with the measurement for all three molecules. The rotational spectroscopy technique for molecules in helium droplets introduced here should apply to a range of molecules and complexes.Comment: ASC and LC contributed equally. 7 pages, 3 figure

Оптимальное управление топливом в системе с запаздыванием

Робота присвячена проблемі синтезу оптимального управління паливом у системі з запізненням. Завдання обмежене по лінійних інваріантних систем заданих управлінням (ІІ-1, ІІ-2). Синтез оптимального управління для досліджувальної системи виявляється з використанням метода максимум Понтрягіна.The paper deals with the synthesis of the fuel-optimal control for the systems with delay in control loop. The considerations are confined to the class of the linear time-invariant systems performed by (II-1, II-2). Synthesis of the optimal control is achieved using the Pontryagin's maximum principle.Работа посвящена проблеме синтеза оптимального управления топливом в системе с запаздыванием. Задача ограничено до линейных инвариантных систем заданных управлением (II-1, II-2). Синтез оптимального управления для исследуемой системы получается с использованием метода максимум Понтрягина

Interparticle interactions:Energy potentials, energy transfer, and nanoscale mechanical motion in response to optical radiation

In the interactions between particles of material with slightly different electronic levels, unusually large shifts in the pair potential can result from photoexcitation, and on subsequent electronic excitation transfer. To elicit these phenomena, it is necessary to understand the fundamental differences between a variety of optical properties deriving from dispersion interactions, and processes such as resonance energy transfer that occur under laser irradiance. This helps dispel some confusion in the recent literature. By developing and interpreting the theory at a deeper level, one can anticipate that in suitable systems, light absorption and energy transfer will be accompanied by significant displacements in interparticle separation, leading to nanoscale mechanical motion

Avicin D: A Protein Reactive Plant Isoprenoid Dephosphorylates Stat 3 by Regulating Both Kinase and Phosphatase Activities

Avicins, a class of electrophilic triterpenoids with pro-apoptotic, anti-inflammatory and antioxidant properties, have been shown to induce redox-dependant post-translational modification of cysteine residues to regulate protein function. Based on (a) the cross-talk that occurs between redox and phosphorylation processes, and (b) the role of Stat3 in the process of apoptosis and carcinogenesis, we chose to study the effects of avicins on the processes of phosphorylation/dephosphorylation in Stat3. Avicins dephosphorylate Stat3 in a variety of human tumor cell lines, leading to a decrease in the transcriptional activity of Stat3. The expression of Stat3-regulated proteins such as c-myc, cyclin D1, Bcl2, survivin and VEGF were reduced in response to avicin treatment. Underlying avicin-induced dephosphorylation of Stat3 was dephosphorylation of JAKs, as well as activation of protein phosphatase-1. Downregulation of both Stat3 activity and expression of Stat 3-controlled pro-survival proteins, contributes to the induction of apoptosis in avicin treated tumor cells. Based on the role of Stat3 in inflammation and wounding, and the in vivo inhibition of VEGF by avicins in a mouse skin carcinogenesis model, it is likely that avicin-induced inhibition of Stat3 activity results in the suppression of the pro-inflammatory and pro-oxidant stromal environment of tumors. Activation of PP-1, which also acts as a cellular economizer, combined with the redox regulation by avicins, can aid in redirecting metabolism from growth promoting anabolic to energy sparing pathways

Safety and risks of nuclear power: Changing the discourse (by the example of Tomsk region)

The paper considers the peculiarities of risk perception in the discourse of the key subjects that form the platform to discuss the development of nuclear energy. The study was conducted in the region with a large nuclear enterprise. The dominant groups setting reference points of perception were revealed. The shift to a “hierarchical” model of ideology was shown. The analysis was based on the cultural theory of risk perception of M.Douglas, A.Wildavsk