246 research outputs found
Propagation and amplification of tide at the northeastern coast of the Antarctic peninsula: an observational study
The amplification and propagation of the tide at the northeastern coast of the Antarctic Peninsula was studied by analysis of instantaneous sea levels measured at the tidal station of Base Esperanza,at the northern end of the Antarctic Peninsula (63゜22.46\u27S, 56゜59.33\u27W) ,at the northeastern coast of Marambio Island (Seymour Island,64゜14.11\u27S, 56゜34.51\u27W) and near Base Matienzo,Larsen nunatak (64゜54.23\u27S, 60゜2.60\u27W) at the edge of the Larsen ice-shelf. By means of harmonic analysis the amplitudes and phases of the most energetic ten tidal constituents were obtained.The tidal regime was typified by means of the factor F and a preponderantly semidiurnal mixed tide was obtained. Signi ficant southward amplification was observed in the amplitudes of semidiurnal constituents,and a less evident amplification was obtained in diurnal ones.Consequently,slightly southward diminution in factor F,from 0.75 (Esperanza) to 0.6 (Matienzo),was found.Bothsouthward amplification in amplitudes and northward propagation of the main tidal constituents obtained from numerical global models show good agreement with the present observations
A numerical study of the ocean circulation around the northern Antarctic Peninsula: Barotropic response to tidal forcing
A high-resolution shallow water model was implemented to study tidal propagation around the northern Antarctic Peninsula. Numerical experiments were done using a grid with 3.00′longitude and 1.05′latitude resolution. Amplitudes and phases of the four main tidal constituents (M_2, S_2, K_1 and O_1) were used to force the model. Modeled sea levels and currents were compared with observations. The modeled cotidal, corange and tidal ellipse axis obtained by harmonic analysis from model results are in good agreement with those of available observations. Given the good correspondence between harmonic constants obtained from model results and from observed hourly sea levels, the energy flux and dissipation by bottom friction were computed. The most intense energy fluxes are related to the semidiurnal constituents. The highest values are present in the Weddell Sea and the energy flux shows a relative maximum at the Antarctic Strait, flowing from the Weddell Sea to Bransfield Strait. Nearly all the dissipation occurs in the Antarctic Strait (maximum value ~0.25Wm^(-2)) and around the South Shetland Islands. The total tidal energy lost to bottom friction in our 4-constituent model is about 1.5GW, giving a domain-averaged value of ~0.002Wm^(-2)
Rethinking the Building Envelope as an Intelligent Community Hub for Renewable Energy Sharing
The widespread use of electric vehicles is hampered by the lack of an adequate charging points network. Likewise, and depending on the use, there could be a lack of correspondence between energy use and production in buildings equipped with renewable energy production systems. For these reasons, a modular device, which could be fully integrated into the building envelope, has been developed. The aim of the project was both to regenerate the existing building envelope and to enhance the newest one, adding new functions. The main goal will be the support of the growth of an electric power-sharing attitude capable of promoting the widespread use of electric vehicles of electric vehicle (EV), supporting strategic actions to retrofit/convert a private building in shared spaces for EV mobility, ensuring enough coverage for charging devices and reducing costs for public administration
Multi-scale stochastic organization-oriented coarse-graining exemplified on the human mitotic checkpoint
The complexity of biological models makes methods for their analysis and understanding highly desirable. Here, we demonstrate the orchestration of various novel coarse-graining methods by applying them to the mitotic spindle assembly checkpoint. We begin with a detailed fine-grained spatial model in which individual molecules are simulated moving and reacting in a three-dimensional space. A sequence of manual and automatic coarse-grainings finally leads to the coarsest deterministic and stochastic models containing only four molecular species and four states for each kinetochore, respectively. We are able to relate each more coarse-grained level to a finer one, which allows us to relate model parameters between coarse-grainings and which provides a more precise meaning for the elements of the more abstract models. Furthermore, we discuss how organizational coarse-graining can be applied to spatial dynamics by showing spatial organizations during mitotic checkpoint inactivation. We demonstrate how these models lead to insights if the model has different “meaningful” behaviors that differ in the set of (molecular) species. We conclude that understanding, modeling and analyzing complex bio-molecular systems can greatly benefit from a set of coarse-graining methods that, ideally, can be automatically applied and that allow the different levels of abstraction to be related
Estudio de la marea en el borde de la barrera Larsen, Mar de Weddell noroccidental
El objetivo de este trabajo es el estudio de la marea en el borde de la barrera Larsen (latitud: 64° 54' 14" S, longitud: 60° 02' 36" W) en el mar de Weddell noroccidental, Antártida. Los niveles del mar se registraron con un sensor de presión y mediante nivelación geométrica (mira y nivel). El coeficiente de determinación de los niveles del mar obtenidos con ambas técnicas es de 0.96. Se presentan las constantes armónicas de las componentes de marea más energéticas.
Se realiza un análisis comparativo entre las constantes calculadas y las que surgen de modelos mareológicos globales y se discute la propagación de la marea en el mar de Weddell noroccidental. Se tipificó el régimen de marea cuantitativamente mediante el coeficiente de Courtier resultando un régimen mixto preponderantemente semidiurno. Los niveles del mar registrados en esta zona de la Antártida son inéditos debido a que el sitio de mediciones fue inaccesible durante muchos años.The objective of this paper is the study of the tide at the Larsen iceshelf boundary (latitude: 64° 54' 14" S, longitude: 60° 02' 36" W), Northwestern Weddell Sea, Antarctica. Sea levels were recorded using pressure sensor and geometric leveling (sight and level). The determination coefficient from sea level gathered with both methods is 0.96. Harmonic constants of the most energetic tidal constituents are presented. A comparative analysis between calculated harmonic constants and those obtained from tidal global models is made and tidal propagation in the Northwestern Weddell Sea is discussed. Tidal regimen is quantified by means of the Courtier coefficient and a preponderantly semidiurnal mixed tide is obtained. Sea levels gathered in this zone of the Antarctica are completely new because the place where the measurements were made was inaccessible for a large period of years.Asociación Argentina de Geofísicos y Geodesta
Estudio de la marea en el borde de la barrera Larsen, Mar de Weddell noroccidental
El objetivo de este trabajo es el estudio de la marea en el borde de la barrera Larsen (latitud: 64° 54' 14" S, longitud: 60° 02' 36" W) en el mar de Weddell noroccidental, Antártida. Los niveles del mar se registraron con un sensor de presión y mediante nivelación geométrica (mira y nivel). El coeficiente de determinación de los niveles del mar obtenidos con ambas técnicas es de 0.96. Se presentan las constantes armónicas de las componentes de marea más energéticas.
Se realiza un análisis comparativo entre las constantes calculadas y las que surgen de modelos mareológicos globales y se discute la propagación de la marea en el mar de Weddell noroccidental. Se tipificó el régimen de marea cuantitativamente mediante el coeficiente de Courtier resultando un régimen mixto preponderantemente semidiurno. Los niveles del mar registrados en esta zona de la Antártida son inéditos debido a que el sitio de mediciones fue inaccesible durante muchos años.The objective of this paper is the study of the tide at the Larsen iceshelf boundary (latitude: 64° 54' 14" S, longitude: 60° 02' 36" W), Northwestern Weddell Sea, Antarctica. Sea levels were recorded using pressure sensor and geometric leveling (sight and level). The determination coefficient from sea level gathered with both methods is 0.96. Harmonic constants of the most energetic tidal constituents are presented. A comparative analysis between calculated harmonic constants and those obtained from tidal global models is made and tidal propagation in the Northwestern Weddell Sea is discussed. Tidal regimen is quantified by means of the Courtier coefficient and a preponderantly semidiurnal mixed tide is obtained. Sea levels gathered in this zone of the Antarctica are completely new because the place where the measurements were made was inaccessible for a large period of years.Asociación Argentina de Geofísicos y Geodesta
Equações não lineares para determinar a curva de crescimento de suínos imunocastrados
The objective of this work was to compare the performance of the nonlinear Gompertz, logistic, and von Bertalanffy equations, to describe the growth curve of immunocastrated male pigs from birth until reaching 140 kg body weight. Standard error, number of iterations, mean square of the error, and coefficient of determination were compared between the models. The logistic and von Bertalanffy equations do not accurately estimate the initial and slaughter weights. The Gompertz equation shows the highest reliability and is, therefore, the most suitable one to describe the growth curve of immunocastrated pigs from birth until 140 kg body weight is reached.O objetivo deste trabalho foi comparar o desempenho das equações não lineares de Gompertz, logística e a de von Bertalanffy, para descrever a curva de crescimento de suínos machos imunocastrados, desde o nascimento até atingirem 140 kg de massa corporal. O erro-padrão, o número de iterações, o quadrado médio do erro e o coeficiente de determinação foram comparados entre os modelos. A equação logística e a de von Bertalanffy não estimam com precisão as massas inicial e de abate. A equação de Gompertz apresenta maior confiabilidade e é, portanto, a mais adequada para descrever a curva de crescimento de suínos imunocastrados, desde o nascimento até a obtenção de140 kg de massa corporal
Sistemi zootecnici delle aree alpine
Viene presentato il panorama italiano sulla zootecnia alpina, evidenziandone i punti di forza e le criticit\ue0 attraverso le varie aree dell'arco alpino
A Randomized Trial of Convalescent Plasma in Covid-19 Severe Pneumonia
BACKGROUND:Convalescent plasma is frequently administered to patients with Covid-19 and hasbeen reported, largely on the basis of observational data, to improve clinical outcomes.Minimal data are available from adequately powered randomized, controlled trials.
METHODS:We randomly assigned hospitalized adult patients with severe Covid-19 pneumoniain a 2:1 ratio to receive convalescent plasma or placebo. The primary outcome wasthe patient?s clinical status 30 days after the intervention, as measured on a six-pointordinal scale ranging from total recovery to death.
RESULTS:A total of 228 patients were assigned to receive convalescent plasma and 105 toreceive placebo. The median time from the onset of symptoms to enrollment inthe trial was 8 days (interquartile range, 5 to 10), and hypoxemia was the mostfrequent severity criterion for enrollment. The infused convalescent plasma had amedian titer of 1:3200 of total SARS-CoV-2 antibodies (interquartile range, 1:800 to1:3200]. No patients were lost to follow-up. At day 30 day, no significant differencewas noted between the convalescent plasma group and the placebo group in thedistribution of clinical outcomes according to the ordinal scale (odds ratio, 0.83(95% confidence interval [CI], 0.52 to 1.35; P=0.46). Overall mortality was 10.96%in the convalescent plasma group and 11.43% in the placebo group, for a risk difference of −0.46 percentage points (95% CI, −7.8 to 6.8). Total SARS-CoV-2 antibodytiters tended to be higher in the convalescent plasma group at day 2 after the intervention. Adverse events and serious adverse events were similar in the two groups.
CONCLUSIONS:no significant differences were observed in clinical status or overall mortality between patients treated with convalescent plasma and those who received placebo.(PlasmAr ClinicalTrials.gov number, NCT04383535.)Fil: Simonovich, Ventura A.. Hospital Italiano. Departamento de Medicina. Servicio de Clinica Medica.; ArgentinaFil: Burgos Pratx, Leandro D.. Hospital Italiano. Departamento de Medicina. Servicio de Clinica Medica.; ArgentinaFil: Scibona, Paula. Hospital Italiano. Departamento de Medicina. Servicio de Clinica Medica.; ArgentinaFil: Beruto, Maria Valeria. No especifíca;Fil: Vallone, Miguel Gabriel. No especifíca;Fil: Vázquez, C.. No especifíca;Fil: Savoy, N.. No especifíca;Fil: Giunta, Diego Hernan. No especifíca;Fil: Pérez, L.G.. No especifíca;Fil: Sánchez, M.L.. No especifíca;Fil: Gamarnik, Andrea Vanesa. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; ArgentinaFil: Ojeda, D.S.. No especifíca;Fil: Santoro, D.M.. No especifíca;Fil: Camino, P. J.. No especifíca;Fil: Antelo, S.. No especifíca;Fil: Rainero, K.. No especifíca;Fil: Vidiella, G. P.. No especifíca;Fil: Miyazaki, E. A.. No especifíca;Fil: Cornistein, W.. No especifíca;Fil: Trabadelo, O. A.. No especifíca;Fil: Ross, F. M.. No especifíca;Fil: Spotti, M.. No especifíca;Fil: Funtowicz, G.. No especifíca;Fil: Scordo, W. E.. No especifíca;Fil: Losso, M. H.. No especifíca;Fil: Ferniot, I.. No especifíca;Fil: Pardo, P. E.. No especifíca;Fil: Rodriguez, E.. No especifíca;Fil: Rucci, P.. No especifíca;Fil: Pasquali, J.. No especifíca;Fil: Fuentes, N. A.. No especifíca;Fil: Esperatti, M.. No especifíca;Fil: Speroni, G. A.. No especifíca;Fil: Nannini, Esteban. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Inmunología Clinica y Experimental de Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Instituto de Inmunología Clinica y Experimental de Rosario; ArgentinaFil: Matteaccio, A.. No especifíca;Fil: Michelangelo, H.G.. No especifíca;Fil: Follmann, D.. No especifíca;Fil: Lane, H. Clifford. No especifíca;Fil: Belloso, Waldo Horacio. Hospital Italiano. Departamento de Medicina. Servicio de Clinica Medica.; Argentin
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