Arctic polar vortex dynamics during winters 2014/2015 and 2020/2021

The dynamic barrier of the polar vortex contributes to lowering the temperature inside the vortex in the lower stratosphere and prevents the penetration of air masses into the vortex. The presence of a dynamic barrier during winter is one of the criteria determining the possibility of ozone depletion from late winter to spring. We considered the dynamics of the Arctic polar vortex in the winters of 2014/2015 and 2020/2021 at the 50, 30 and 10 hPa levels by the vortex delineation method using the geopotential. In early January 2015 and 2021, sudden stratospheric warmings were recorded as a result of the splitting (4 January 2015) and the significant displacement (5 January 2021) of the polar vortex. In both cases, the weakening of the dynamic barrier of the polar vortex was observed. The polar vortex is characterized by the presence of a dynamic barrier, when the wind speed along the entire edge of the vortex is more than 20, 24 and 30 m/s at the 50, 30 and 10 hPa levels, respectively. A decrease in the average wind speed along the vortex edge below 30, 36 and 45 m/s, at the 50, 30 and 10 hPa levels, respectively, usually indicates a local decrease in the wind speed below 20, 24 and 30 m/s at these levels, i.e., indirectly indicates a weakening of the dynamic barrier.The dynamic barrier of the polar vortex contributes to lowering the temperature inside the vortex in the lower stratosphere and prevents the penetration of air masses into the vortex. The presence of a dynamic barrier during winter is one of the criteria determining the possibility of ozone depletion from late winter to spring. We considered the dynamics of the Arctic polar vortex in the winters of 2014/2015 and 2020/2021 at the 50, 30 and 10 hPa levels by the vortex delineation method using the geopotential. In early January 2015 and 2021, sudden stratospheric warmings were recorded as a result of the splitting (4 January 2015) and the significant displacement (5 January 2021) of the polar vortex. In both cases, the weakening of the dynamic barrier of the polar vortex was observed. The polar vortex is characterized by the presence of a dynamic barrier, when the wind speed along the entire edge of the vortex is more than 20, 24 and 30 m/s at the 50, 30 and 10 hPa levels, respectively. A decrease in the average wind speed along the vortex edge below 30, 36 and 45 m/s, at the 50, 30 and 10 hPa levels, respectively, usually indicates a local decrease in the wind speed below 20, 24 and 30 m/s at these levels, i.e., indirectly indicates a weakening of the dynamic barrier

The effect of anthracene derivatives on the state of the extracellular matrix of the periodontal connective tissue and the oral mucosa of old rats

In the experiments on 27 old female rats, the effect of the anthracene derivative preparation on the state of the intercellular matrix of the connective tissue of the periodontal and oral mucosa in intact animals, as well as on the periodontitis model, was studied

The role of polymorphic variants of arginase genes (<i>ARG1, ARG2</i>) involved in beta-2-agonist metabolism in the development and course of asthma

Asthma is a common severe disease of the respiratory tract, it leads to a significant impairment in the quality of a patient’s life unless effectively treated. Uncontrolled asthma symptoms are a cause of disease progression and development, they lead to an increase in the patient’s disability. The sensitivity to asthma therapy largely depends on the interaction of genetic and epigenetic factors, which account for about 50–60 % of variability of therapeutic response. Beta-2-agonists are some of the major class of bronchodilators used for asthma management. According to published data, allelic variants of the arginase ARG1 and ARG2 genes are associated with a risk of asthma development, spirometry measures and efficacy of bronchodilator therapy. High arginase activity results in a low level of plasma L-arginine and in a decrease in nitric oxide, and, as a result, in an increase in airway inflammation and remodeling. Arginase genetic polymorphisms (rs2781667 of the ARG1 gene, rs17249437, rs3742879, rs7140310 of the ARG2 gene) were studied in 236 children with asthma and 194 unrelated healthy individuals of Russian, Tatar and Bashkir ethnicity from the Republic of Bashkortostan. Association analysis of the studied polymorphisms with asthma development and course, the sensitivity to therapy in patients was carried out. It was found that the rs2781667*C allele of the ARG1 gene is a marker of an increased risk of asthma in Tatars. In Russians, the association of rs17249437*TT and rs3742879*GG genotypes of the ARG2 gene with a decrease in spirometry measures (FEV1, MEF25) was established. In Russians and Tatars receiving glucocorticoid monotherapy or combination therapy, the association of the rs17249437*T allele and rs17249437*TT genotype of the ARG2 gene with a partially controlled and uncontrolled course of asthma was shown

COVID - 19 as a challenge to the economy, society, politics

The article examines the main aspects of economic, social and political problems, the formation and development of which is due to the global crisis caused by the COVID-19 pandemic. The negative aspects and consequences of the pandemic for the world economy are revealed.В статье рассмотрены основные аспекты экономических, социальных и политических проблем, формирование и развитие которых обусловлено мировым кризисом вызванных пандемией COVID-19. Выявлены негативные стороны и последствия пандемии для мировой экономики

Взаимосвязь между площадью и скоростью ветра по границе антарктического полярного вихря

The Antarctic polar vortex forms in autumn, intensifies in the winter-spring period and decays in late spring. Inside the vortex in the lower stratosphere, favorable conditions are created for the annual spring ozone depletion. One of the conditions for the formation of the Antarctic ozone hole is the presence of a dynamic barrier along the vortex edge in the winter-spring period, which contributes to a decrease in temperature inside the vortex (necessary for the existence of polar stratospheric clouds) and prevents the penetration of air masses into the vortex. The dynamic barrier exists when the wind speed along the vortex edge in the lower stratosphere is at least 20 m/s. When the vortex area decreases below 10 million km2 , the dynamic barrier usually weakens, preceded by the vortex breakdown. The purpose of this work is to consider the relationship between the vortex area and the wind speed along the vortex edge using the Antarctic polar vortex as an example. To analyze the dynamics of the Antarctic polar vortex, we used a method based on vortex delineation, which makes it possible to calculate the vortex area and wind speed along the vortex edge using geopotential values determined from the maximum values of temperature gradient and wind speed and, thus, characterizing the polar vortex edges. Seasonal variations in the vortex area are mainly determined by the time of the beginning, peak and end of the polar night. In turn, seasonal changes in wind speed along the edge of the Antarctic vortex are additionally determined by the influence of the temperature of the lower subtropical stratosphere. To eliminate the influence of the seasonal variation, polynomial trends were removed from the time series of the parameters considered. We have shown that the relationship between the vortex area and the wind speed along the vortex edge can be traced for area values of less than 25 million km2 and more than 50 million km2 . At small values of the vortex area (&lt; 25 million km2), during its formation and destruction, a positive correlation appears between the vortex area and the wind speed along the vortex edge. At high values of the vortex area (&gt; 50 million km2), a negative correlation can be traced between the parameters studied.Одним из условий формирования полярной озоновой аномалии является наличие динамического барьера по границе полярного вихря в зимне-весенний период, существующего при скорости ветра по границе вихря в нижней стратосфере не менее 20 м/с и площади вихря более 10 млн км2 . Целью данной работы является исследование взаимосвязи между площадью вихря и скоростью ветра по границе вихря на примере антарктического полярного вихря. В работе использовался метод оконтуривания вихрей на основе значений геопотенциала, определенных по максимальным значениям градиента температуры и скорости ветра. Показано, что взаимосвязь между площадью вихря и скоростью ветра по границе вихря прослеживается при значениях площади менее 25 млн км2 (положительная корреляция) и более 50 млн км2 (отрицательная корреляция).

GEOCHEMICAL FEATURES OF DIKE AILLIKITES AND ALKALINE ROCKS OF THE BOLSHETAGNINSKY MASSIF (URIK-IYA GRABEN, EAST SAYAN REGION)

The ICP-MS determinations have been made on microelement content of ~650–640 Ma ultramafic lamprophyre-aillikite dikes and alkaline silicate rocks and carbonatites from the Bolshetagninsky ijolite-syenite massif, spatially overlapped in the northern Urik-Iya graben on the southwestern margin of the Siberian craton. There have been identified two types of spectra of microelement distribution, typical of the Bolshetagninsky massif aillikites and alkaline silicate rocks, respectively; both types of spectra demonstrate significant (more than two orders of magnitude) enrichment in most incompatible elements relative to the primitive mantle. Aillikites have tilt-left distribution spectra of rare elements with Rb, К, Pb, Sr-P, Zr-Hf, ±U minimums and less-pronounced Y minimum. Multi-element spectra of ijolites-melteigites are characterized by Th, Та, Pb, Hf, ±Zr, ±Ti minimums which is also reflected in nepheline syenite and carbonatite spectra. The Bolshetagninsky massif aillikites and alkaline rocks differ also in Nb/Ta, Zr/Hf, Th/Nb, Th/U ratios. Geochemical differences imply that the parental melts of dike aillikites and alkaline rocks are derived from different mantle sources

Joint work of the university and practical public health - pledge of successful implementation national project «Public health»

The article presents the directions of joint work of the MAU DGKB No. 11 of Ekaterinburg and the Department of Outpatient Pediatrics and Pediatrics of the FPK and PP Federal State Budgetary Educational Institution of the Ural State Medical University of the Ministry of Health of Russia as a demonstration of a successful example of interaction between the university and the clinical base in determining competent and relevant personnel for the health care system and implementing the development and implementation of effective innovative technologies for the diagnosis, treatment and rehabilitation of children for the successful implementation of the national project "Health Care'В статье представлены направления совместной работы МАУ ДГКБ №11 г. Екатеринбурга и кафедры поликлинической педиатрии и педиатрии ФПК и ПП ФГБОУ ВО УГМУ Минздрава России, как демонстрация успешного примера взаимодействия вуза и клинической базы в вопросах определяющих подготовку компетентных и востребованных кадров для системы здравоохранения и осуществляющих разработку и внедрение в практику эффективных инновационных технологий диагностики, лечения и реабилитации детей для успешной реализации национального проекта «Здравоохранение»

Lidar observations of pyrocumulonimbus smoke plumes in the UTLS over Tomsk (Western Siberia, Russia) from 2000 to 2017

Large volcanic eruptions with the volcanic explosivity index (VEI)&thinsp;≥&thinsp;3 are widely known to be the strongest source of long-lived aerosol in the upper troposphere and lower stratosphere (UTLS). However, the latest studies have revealed that massive forest (bush) fires represent another strong source of short-term (but intense) aerosol perturbations in the UTLS if combustion products from the fires reach these altitudes via convective ascent within pyrocumulonimbus clouds (pyroCbs). PyroCbs, generated by boreal wildfires in North America and northeastern Asia and injecting smoke plumes into the UTLS, have been intensively studied using both ground- and space-based instruments since the beginning of the 21st century. In this paper, we focus on aerosol layers observed in the UTLS over Tomsk (56.48∘&thinsp;N, 85.05∘&thinsp;E, Western Siberia, Russia) that could be smoke plumes from such pyroCb events occurring in the 2000–2017 period. Using the HYSPLIT trajectory analysis, we have reliably assigned nine aerosol layers to 8 out of more than 100 documented pyroCb events, the aftereffects of which could potentially be detected in the UTLS over Tomsk. All the eight pyroCb events occurred in the USA and Canada: one event per year occurred in 2000, 2002, 2003, 2013, 2015, and 2016, whereas two events occurred in 2017. No plumes from pyroCbs originating in the boreal zone of Siberia and the Far East (to the east of Tomsk) were observed in the UTLS over Tomsk between 2000 and 2017. We conclude that the time durations for pyroCb plumes to be detected in the UTLS using ground-based lidars are less than about a month, i.e., plumes from pyroCbs generated by wildfires to the east of Tomsk can significantly diffuse before reaching the Tomsk lidar station by the westerly zonal transport of air masses. A comparative analysis of the contributions from pyroCb events and volcanic eruptions with VEI&thinsp;≥&thinsp;3 to aerosol loading of the UTLS over Tomsk showed the following. Plumes from two or more pyroCbs that have occurred in North America in a single year are able to markedly increase the aerosol loading compared to the previous year. The annual average value of the integrated aerosol backscatter coefficient Bπ,532a increased by 14.8&thinsp;% in 2017 compared to that in 2016 due to multiple pyroCbs occurring in British Columbia (Canada) in August 2017. The aftereffects of pyroCb events are comparable to those of volcanic eruptions with VEI&thinsp;≤&thinsp;3, but even multiple pyroCbs can hardly compete with volcanic eruptions with VEI&thinsp;=&thinsp;4.</p

Different morphological structures of breast tumors demonstrate individual drug resistance gene expression profiles

AIM