How does star formation proceed in the circumnuclear starburst ring of NGC 6951?

Gas inflowing along stellar bars is often stalled at the location of circumnuclear rings, that form an effective reservoir for massive star formation and thus shape the central regions of galaxies. However, how exactly star formation is proceeding within these circumnuclear starburst rings is subject of debate. Two main scenarios for this process have been put forward: In the first the onset of star formation is regulated by the total amount of gas present in the ring with star forming starting once a mass threshold has reached in a `random' position within the ring like `popcorn'. In the second star formation preferentially takes place near the locations where the gas enters the ring. This scenario has been dubbed `pearls-on-a-string'. Here we combine new optical IFU data covering the full stellar bar with existing multi-wavelength data to study in detail the 580 pc radius circumnuclear starburst ring in the nearby spiral galaxy NGC 6951. Using HST archival data together with Sauron and Oasis IFU data, we derive the ages and stellar masses of star clusters as well as the total stellar content of the central region. Adding information on the molecular gas distribution, stellar and gaseous dynamics and extinction, we find that the circumnuclear ring in NGC 6951 is ~1-1.5 Gyr old and has been forming stars for most of that time. We see evidence for preferred sites of star formation within the ring, consistent with the `pearls-on-a-string' scenario, when focusing on the youngest stellar populations. Due to the ring's longevity this signature is washed out when older stellar populations are included in the analysis.Comment: accepted for publication in A&A, 15 page

Estimation of Treatment Effects in Randomized Trials with Noncompliance and a Dichotomous Outcome

We propose a class of estimators of the treatment effect on a dichotomous outcome among the treated subjects within covariate and treatment arm strata in randomized trials with non-compliance. Recent articles by Vansteelandt and Goethebeur (2003) and Robins and Rotnitzky (2004) have presented consistent and asymptotically linear estimators of a causal odds ratio, which rely, beyond correct specification of a model for the causal odds ratio, on a correctly specified model for a potentially high dimensional nuisance parameter. In this article we propose consistent, asymptotically linear and locally efficient estimators of a causal relative risk and a new parameter -- called a switch causal relative risk -- which only rely on the correct specification of a model for the parameter of interest. As in Vansteelandt and Goethebeur (2003) and Robins and Rotnitzky (2004) our estimators are always consistent, asymptotically linear at the null hypothesis of no-treatment effect, thereby providing valid testing procedures. We examine the finite sample properties of these instrumental variable-based estimators and the associated testing procedures in simulations and a data analysis of decaffeinated coffee consumption and miscarriage

Summary of random vibration prediction procedures

Summary of random vibration prediction procedures for aerospace vehicles, with bibliograph

Meta-analysis of 701 published cases of sinonasal neuroendocrine carcinoma:The importance of differentiation grade in determining treatment strategy

AbstractThe aim of this meta-analysis was to provide treatment guidelines for sinonasal neuroendocrine carcinoma (SNC) by combining all available data in the literature.A literature search for all studies concerning SNC was performed against the MEDLINE and EMBASE databases. Available clinical data was normalized, pooled, and statistically analyzed.A total of 701 cases of SNC were available for analysis, comprising 127 well or moderately differentiated sinonasal neuroendocrine carcinomas (SNEC), 459 sinonasal undifferentiated carcinoma (SNUC) and 115 sinonasal small cell carcinoma (SmCC). Tumor type was the most important predictor of survival, with a 5-year disease-specific survival (DSS) of 70.2% for SNEC, 35.9% for SNUC and 46.1% for SmCC. Tumor stage on presentation was of limited value in predicting survival or response to treatment. Overall, the application of surgery yielded significantly better results (5-year DSS 52.2% versus 30.1%, p<0.001). In SNUC, radiotherapy was a beneficial supplement to surgery (5-year DSS 54.7% versus 15.7%, p=0.027), while radiotherapy as monotherapy performed poorly (5-year DSS 17.9%). Chemotherapy did not appear to contribute to survival.Based on these findings, we can conclude that the most important predictors of survival in SNC are differentiation grade and the associated choice of treatment modality. In contrast to other head and neck cancers, tumor staging appears of limited value in predicting survival or deciding on a treatment strategy. Surgery should be the cornerstone of treatment, supplemented by radiotherapy in poorly differentiated subtypes (SNUC, SmCC). Chemotherapy does not appear to contribute to survival

Explaining two circumnuclear star forming rings in NGC5248

The distribution of gas in the central kiloparsec of a galaxy has a dynamically rapid evolution. Nonaxisymmetries in the gravitational potential of the galactic disk, such as a large scale stellar bar or spiral, can lead to significant radial motion of gaseous material from larger radii to the central region. The large influx of gas and the subsequent star formation keep the central region constantly changing. However, the ability of gas to reach the nucleus proper to fuel an AGN phase is not guaranteed. Gas inflow can be halted at a circumnuclear star forming ring several hundred parsec away. The nearby galaxy NGC5248 is especially interesting in this sense since it is said to host 2 circumnuclear star forming rings at 100pc and 370pc from its quiescent nucleus. Here we present new subarcsecond PdBI+30m CO(2-1) emission line observations of the central region. For the first time the molecular gas distribution at the smallest stellar ring is resolved into a gas ring, consistent with the presence of a quiescent nucleus. However, the molecular gas shows no ring structure at the larger ring. We combine analyses of the gaseous and stellar content in the central kiloparsec of this galaxy to understand the gas distribution and dynamics of this star forming central region. We discuss the probability of two scenarios leading to the current observations, given our full understanding of this system, and discuss whether there are really two circumnuclear star forming rings in this galaxy.Comment: Accepted for publication in A&A, 14pages + long tabl

Therapeutic suggestion has no effect on postoperative morphine requirements

This study was designed to confirm the effect of therapeutic intraoperative auditory suggestion on recovery from anesthesia, to establish the effect of preoperative suggestion, and to assess implicit memory for intraoperative information using an indirect memory task. Sixty consenting unpremedicated patients scheduled for elective gynecologic surgery were randomly divided into three equal groups: Group 1 received a tape of therapeutic suggestions preoperatively and the story of Robinson Crusoe intraoperatively; Group 2 heard the story of Peter Pan preoperatively and therapeutic suggestions intraoperatively; Group 3 heard the Crusoe story preoperatively and the Peter Pan story intraoperatively. A standardized anesthetic technique was used with fentanyl, propofol, isoflurane, and nitrous oxide. After surgery, all patients received patient-controlled analgesia (PCA) with a standardized regimen. In the 24 h postsurgery, morphine use was recorded every 6 h and at 24 h an indirect memory test(free association) was used to test for memory of the stories. Anxiety scores were measured before surgery and at 6 and 24 h postsurgery. There were no significant differences between groups for postoperative morphine rise, pain or nausea scores, anxiety scores, or days spent in hospital after surgery. Seven of 20 patients who heard the Pan story intraoperatively gave a positive association with the word 'Hook,' whereas 2 of 20 who did not hear the story gave such all association. Indirect memory for the Pan story was established using confidence interval (CI) analysis. (The 95% CI for difference in proportion did not include zero). No indirect memory for the Crusoe story could be demonstrated. This study did not confirm previous work which suggested that positive therapeutic auditory suggestions, played intraoperatively, reduced PCA morphine requirements. In contrast, a positive implicit memory effect was found for a story presented intraoperatively

Probing ferroelectricity in PbZr

The reduction in symmetry associated with the onset of ferroelectric order in PbZr{sub 0.2}Ti{sub 0.8}O{sub 3} (PZT) thin films leads to a pronounced difference at the Ti L{sub 3,2} absorption edges between spectra measured with the x-ray linear polarization perpendicular and parallel to the ferroelectric polarization. We introduce a general method to analyze the observed difference spectra using atomic multiplet calculations. Moreover, we find experimental evidence for structural changes in PZT induced by the reversal of the ferroelectric polarization

Molecular gas in NUclei of GAlaxies (NUGA) XV. Molecular gas kinematics in the inner 3kpc of NGC6951

Within the NUclei of GAlaxies project we have obtained IRAM PdBI and 30m 12CO(1-0) and 12CO(2-1) observations of the spiral galaxy NGC 6951. Previous work shows that there is indirect evidence of gas inflow from 3 kpc down to small radii: a large-scale stellar bar, a prominent starburst ring (r~580 pc) and a LINER/Seyfert 2 nucleus. In this paper we study the gas kinematics as traced by the CO line emission in detail. We quantify the influence of the large-scale stellar bar by constructing an analytical model of the evolution of gas particles in a barred potential. From this model gravitational torques and mass accumulation rates are computed. We compare our model-based gravitational torque results with previous observationally-based ones. The model also shows that the large-scale stellar bar is indeed the dominant force for driving the gas inward, to the starburst ring. Inside the ring itself a nuclear stellar oval might play an important role. Detailed analysis of the CO gas kinematics there shows that emission arises from two co-spatial, but kinematically distinct components at several locations. The main emission component can always be related to the overall bar-driven gas kinematics. The second component exhibits velocities that are larger than expected for gas on stable orbits, has a molecular gas mass of 1.8x10^6Msun, is very likely connected to the nuclear stellar oval, and is consistent with inflowing motion towards the very center. This may form the last link in the chain of gas inflow towards the active galactic nucleus in NGC 6951.Comment: 17 pages, accepted by A&A (17 feb 2011

Strain dependence of the Mn anisotropy in ferromagnetic semiconductors observed by x-ray magnetic circular dichroism

We demonstrate sensitivity of the Mn 3d valence states to strain in the ferromagnetic semiconductors (Ga,Mn)As and (Al,Ga,Mn)As, using x-ray magnetic circular dichroism (XMCD). The spectral shape of the Mn $L_{2,3}$ XMCD is dependent on the orientation of the magnetization, and features with cubic and uniaxial dependence are distinguished. Reversing the strain reverses the sign of the uniaxial anisotropy of the Mn $L_3$ pre-peak which is ascribed to transitions from the Mn 2p core level to p-d hybridized valence band hole states. With increasing carrier localization, the $L_3$ pre-peak intensity increases, indicating an increasing 3d character of the hybridized holes.Comment: 4 pages plus 2 figures, accepted for publication in Physical Review