Restructuring and Rebranding: The Need for Another Revolution in the Loire

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Bioerosion on a Terebratula scillae population from the Lower Pleistocene of Lecce area (Southern Italy)

This paper deals with shell bioerosion in a population of Terebratula scillae SEGUENZA from the Lower Pleistocene in Lecce area, Southern Italy. The most important traces belong to shell breakage attributed to predatory activity; borings (Entobia isp., Maeandropolydora isp.); drill holes (Oichnus simplex BROMLEY; Oichnus isp.); and etching scars (Centrichnus eccentricus BROMLEY and MARTINELL; Podichnus centrifugalis BROMLEY and SURLYK). The distribution analysis of the traces of epibiosis on the shells of T. scillae induces us to think that we are dealing with a pedicle-anchored form, living with completely raised valves. Besides, both percentage and nature of predation marks (probably due to gastropods or decapod crustaceans) do not depose for a very intense predation pressure.El presente artículo trata sobre la bioerosión en las conchas de una población de Terebratula scillae SEGUENZA del Pleistoceno inferior del área de Lecce, Sur de Italia. Las principales trazas pertenecen a roturas de la concha atribuidas a la actividad de depredadores; perforaciones (Entobia isp., Maeandropolydora isp.); agujeros (Oichnus simplex BROMLEY; Oichnus isp.); e impresiones (Centrichnus eccentricus BROMLEY and MARTINELL; Podichnus centrifugalis BROMLEY and SURLYK). El análisis de la distribución de las trazas de epibiosis sobre las conchas de T. scillae induce a pensar que se trata de una forma anclada mediante el pedículo, que vivía con las valvas completamente levantadas. Por otra parte, ni los porcentajes ni la naturaleza de las señales de depredación (probablemente debidas a gasterópodos o a crustáceos decápodos) indican una presión de depredación demasiado intensa

Crossed Andreev reflection-induced magnetoresistance

We show that very large negative magnetoresistance can be obtained in magnetic trilayers in a current-in-plane geometry owing to the existence of crossed Andreev reflection. This spin-valve consists of a thin superconducting film sandwiched between two ferromagnetic layers whose magnetization is allowed to be either parallelly or antiparallelly aligned. For a suitable choice of structure parameters and nearly fully spin-polarized ferromagnets the magnetoresistance can exceed -80%. Our results are relevant for the design and implementation of spintronic devices exploiting ferromagnet-superconductor structures.Comment: 5 pages, 4 figures, final published versio

Mutator Dynamics on a Smooth Evolutionary Landscape

We investigate a model of evolutionary dynamics on a smooth landscape which features a ``mutator'' allele whose effect is to increase the mutation rate. We show that the expected proportion of mutators far from equilibrium, when the fitness is steadily increasing in time, is governed solely by the transition rates into and out of the mutator state. This results is a much faster rate of fitness increase than would be the case without the mutator allele. Near the fitness equilibrium, however, the mutators are severely suppressed, due to the detrimental effects of a large mutation rate near the fitness maximum. We discuss the results of a recent experiment on natural selection of E. coli in the light of our model.Comment: 4 pages, 3 figure

VE-cadherin and claudin-5: it takes two to tango

Endothelial barrier function requires the adhesive activity of VE-cadherin and claudin-5, which are key components of adherens and tight endothelial junctions, respectively. Emerging evidence suggests that VE-cadherin controls claudin-5 expression by preventing the nuclear accumulation of FoxO1 and -catenin, which repress the claudin-5 promoter. This indicates that a crosstalk mechanism operates between these junctional structures

Spin-dependent Transparency of Ferromagnet/Superconductor Interfaces

Because the physical interpretation of the spin-polarization of a ferromagnet determined by point-contact Andreev reflection (PCAR) is non-trivial, we have carried out parameter-free calculations of PCAR spectra based upon a scattering-theory formulation of Andreev reflection generalized to spin-polarized systems and a tight-binding linear muffin tin orbital method for calculating the corresponding scattering matrices. PCAR is found to measure the spin-dependent interface transparency rather than the bulk polarization of the ferromagnet which is strongly overestimated by free electron model fitting.Comment: 4 pages, 1figure. submitte

Blockade and Counterflow Supercurrent in exciton-condensate Josephson junctions

We demonstrate that perfect conversion between charged supercurrents in superconductors and neutral supercurrents in electron-hole pair condensates is possible via a new Andreev-like scattering mechanism. As a result, when two superconducting circuits are coupled through a bilayer exciton condensate, the superflow in both layers is drastically modified. Depending on the phase biases the supercurrents can be completely blocked or exhibit perfect drag.Comment: 4 pages, 2 figure

The Error and Repair Catastrophes: A Two-Dimensional Phase Diagram in the Quasispecies Model

This paper develops a two gene, single fitness peak model for determining the equilibrium distribution of genotypes in a unicellular population which is capable of genetic damage repair. The first gene, denoted by $\sigma_{via}$, yields a viable organism with first order growth rate constant $k > 1$ if it is equal to some target ``master'' sequence $\sigma_{via, 0}$. The second gene, denoted by $\sigma_{rep}$, yields an organism capable of genetic repair if it is equal to some target ``master'' sequence $\sigma_{rep, 0}$. This model is analytically solvable in the limit of infinite sequence length, and gives an equilibrium distribution which depends on \mu \equiv L\eps , the product of sequence length and per base pair replication error probability, and \eps_r , the probability of repair failure per base pair. The equilibrium distribution is shown to exist in one of three possible ``phases.'' In the first phase, the population is localized about the viability and repairing master sequences. As \eps_r exceeds the fraction of deleterious mutations, the population undergoes a ``repair'' catastrophe, in which the equilibrium distribution is still localized about the viability master sequence, but is spread ergodically over the sequence subspace defined by the repair gene. Below the repair catastrophe, the distribution undergoes the error catastrophe when $\mu$ exceeds \ln k/\eps_r , while above the repair catastrophe, the distribution undergoes the error catastrophe when $\mu$ exceeds $\ln k/f_{del}$, where $f_{del}$ denotes the fraction of deleterious mutations.Comment: 14 pages, 3 figures. Submitted to Physical Review

Spin current shot noise as a probe of interactions in mesoscopic systems

It is shown that the spin resolved current shot noise can probe attractive or repulsive interactions in mesoscopic systems. This is illustrated in two physical situations : i) a normal-superconducting junction where the spin current noise is found to be zero, and ii) a single electron transistor (SET), where the spin current noise is found to be Poissonian. Repulsive interactions may also lead to weak attractive correlations (bunching of opposite spins) in conditions far from equilibrium. Spin current shot noise can be used to measure the spin relaxation time $T_1$, and a set-up is proposed in a quantum dot geometry.Comment: 5 pages, 4 Figures, revised version, added reference