255 research outputs found
The High Energy Emission of the Crab Nebula from 20 keV to 6 MeV with INTEGRAL
The SPI spectrometer aboard the INTEGRAL mission observes regularly the Crab
Nebula since 2003. We report on observations distributed over 5.5 years and
investigate the variability of the intensity and spectral shape of this
remarkable source in the hard X-rays domain up to a few MeV. While single power
law models give a good description in the X-ray domain (mean photon index ~
2.05) and MeV domain (photon index ~ 2.23), crucial information are contained
in the evolution of the slope with energy between these two values. This study
has been carried out trough individual observations and long duration (~ 400
ks) averaged spectra. The stability of the emission is remarkable and excludes
a single power law model. The slopes measured below and above 100 keV agree
perfectly with the last values reported in the X-ray and MeV regions
respectively, but without indication of a localized break point. This suggests
a gradual softening in the emission around 100 keV and thus a continuous
evolution rather than an actual change in the mechanism parameters. In the MeV
region, no significant deviation from the proposed power law model is visible
up to 5-6 MeV. Finally, we take advantage of the spectroscopic capability of
the instrument to seek for previously reported spectral features in the covered
energy range with negative results for any significant cyclotron or
annihilation emission on 400 ks timescales. Beyond the scientific results, the
performance and reliability of the SPI instrument is explicitly demonstrated,
with some details about the most appropriate analysis method.Comment: accepted for publication in ApJ; 4 figures, 2 table
Testing Lorentz Invariance with GRB021206
Since the discovery of the cosmological origin of GRBs there has been growing
interest in using these transient events to probe the quantum gravity energy
scale in the range 10^16--10^19 GeV, up to the Planck mass scale. This energy
scale can manifest itself through a measurable modification in the
electromagnetic radiation dispersion relation for high energy photons
originating from cosmological distances. We have used data from the gamma-ray
burst (GRB) of 6 December 2002 (GRB021206) to place an upper bound on the
energy dispersion of the speed of light. The limit on the first-order quantum
gravity effects derived from this single GRB indicate that the energy scale is
in excess of 1.8x10^17 GeV. We discuss a program to further constrain the
energy scale by systematically studying such GRBs.Comment: 10 pages, 3 figures, accepted for publication in ApJ
The Advanced Compton Telescope
The Advanced Compton Telescope (ACT), the next major step in gamma-ray astronomy, will probe the fires where chemical elements are formed by enabling high-resolution spectroscopy of nuclear emission from supernova explosions. During the past two years, our collaboration has been undertaking a NASA mission concept study for ACT. This study was designed to (1) transform the key scientific objectives into specific instrument requirements, (2) to identify the most promising technologies to meet those requirements, and (3) to design a viable mission concept for this instrument. We present the results of this study, including scientific goals and expected performance, mission design, and technology recommendations
SPI/INTEGRAL observation of the Cygnus region
We present the analysis of the first observations of the Cygnus region by the
SPI spectrometer onboard the Integral Gamma Ray Observatory, encompassing
600 ks of data. Three sources namely Cyg X-1, Cyg X-3 and EXO 2030+375
were clearly detected. Our data illustrate the temporal variability of Cyg X-1
in the energy range from 20 keV to 300 keV. The spectral analysis shows a
remarkable stability of the Cyg X-1 spectra when averaged over one day
timescale. The other goal of these observations is SPI inflight calibration and
performance verification. The latest objective has been achieved as
demonstrated by the results presented in this paper.Comment: 6 pages, 10 figures, accepted for publication in A&A (special
INTEGRAL volume
MAX: Development of a Laue diffraction lens for nuclear astrophysics
The next generation of instrumentation for nuclear astrophysics will have to achieve an improvement in sensitivity by a factor of 10-100 over present technologies. With the focusing gamma-ray telescope MAX we take up this challenge and propose to combine the required sensitivity with high spectral and angular resolution, and the capability to measure the polarization of the photons. MAX is a space-borne crystal diffraction telescope, featuring a broad-band Laue lens optimized for the observation of compact sources in two wide energy bands of high astrophysical relevance. Gamma rays will be focused from the large collecting area of a crystal diffraction lens onto a very small detector volume. As a consequence, the signal to background ratio is greatly enhanced, leading to unprecedented sensitivities
HDAC9 is implicated in atherosclerotic aortic calcification and affects vascular smooth muscle cell phenotype.
Aortic calcification is an important independent predictor of future cardiovascular events. We performed a genome-wide association meta-analysis to determine SNPs associated with the extent of abdominal aortic calcification (n = 9,417) or descending thoracic aortic calcification (n = 8,422). Two genetic loci, HDAC9 and RAP1GAP, were associated with abdominal aortic calcification at a genome-wide level (P < 5.0 × 10-8). No SNPs were associated with thoracic aortic calcification at the genome-wide threshold. Increased expression of HDAC9 in human aortic smooth muscle cells promoted calcification and reduced contractility, while inhibition of HDAC9 in human aortic smooth muscle cells inhibited calcification and enhanced cell contractility. In matrix Gla protein-deficient mice, a model of human vascular calcification, mice lacking HDAC9 had a 40% reduction in aortic calcification and improved survival. This translational genomic study identifies the first genetic risk locus associated with calcification of the abdominal aorta and describes a previously unknown role for HDAC9 in the development of vascular calcification
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