The Role of Adult Fiddler Crab Environmental Acoustic Cues and Chemical Cues in Stimulating Molting of Field-Caught Megalopae

In mid-Atlantic estuaries, three fiddler crab species, Uca pugilator, Uca pugnax and Uca minax co-occur, with their adults occupying different habitat types distinguished by salinity and sediment size. Some evidence exists that selective settlement is responsible for this separation but the mechanism is largely unknown. We tested the hypothesis that field-caught megalopae would accelerate metamorphosis in the presence of adult species-specific environmental acoustic cues and conspecific chemical cues. We placed megalopae in seawater with and without adult chemical cues, exposed them to one of three sound treatments for 8 days, and recorded the time each megalopa took to metamorphose. In the absence of adult chemical cues, very few megalopae molted regardless of sound treatment. Molting in the presence of habitat sound and chemical cues varied by species. Many U. pugilator molted in all sound and odor combinations, including no odor/sound. U. pugnax was stimulated to molt by chemical cues from either U. pugilator or U. pugnax, but molting was similar across sound treatments. Our results do not support the hypothesis that sound stimulates molting by fiddler crab megalopae, but support the role of chemical odors from adults as molting cues

Evidence on the Efficacy of School-Based Incentives for Healthy Living

We analyze the effects of a school-based incentive program on children's exercise habits. The program offers children an opportunity to win prizes if they walk or bike to school during prize periods. We use daily child-level data and individual fixed effects models to measure the impact of the prizes by comparing behavior during prize periods with behavior during non-prize periods. Variation in the timing of prize periods across different schools allows us to estimate models with calendardate fixed effects to control for day-specific attributes, such as weather and proximity to holidays. On average, we find that being in a prize period increases riding behavior by sixteen percent, a large impact given that the prize value is just six cents per participating student. We also find that winning a prize lottery has a positive impact on ridership over subsequent weeks; consider heterogeneity across prize type, gender, age, and calendar month; and explore differential effects on the intensive versus extensive margins.health; exercise; children; school; incentives; active commuting

A survey of practicing optometrists concerning the dispensing and adjusting of eyewear

A survey of practicing optometrists concerning the dispensing and adjusting of eyewea

Shoulder Ulcers in Sows

A literature review was conducted on shoulder ulcers in sows. Shoulder ulcers are caused by pressure that the shoulder blade exerts against tissues that overlie it. Those issues lose blood supply and die. Because the pressure is directed outward, tissue damage occurs before the ulcer is evident on the skin surface. Ulcer prevalence is highly variable; 0 to more than 20% of the sows in 218 herds evaluated had shoulder ulcers. Ulcers usually develop during late gestation and early lactation and many heal shortly after weaning. Numerous risk factors for developing shoulder ulcers have been identified. Inactivity and thin sow body condition seem to be the most important ulcer risk factors. Thus, farrowing caretakers may be able to prevent ulcers by carefully monitoring each sow’s lying behavior and attempting to fix any problem that restricts movement. Checking the gestation and lactation feeding programs to ensure that sows enter the farrowing area in proper body condition also may prevent ulcers. Experience from Denmark indicates a pad fixed to the shoulder of sows at the first sign of redness in the skin may prevent ulcers too. Sows starting to develop an ulcer benefit from treatment of underlying issues that cause inactivity, daily application of a topical disinfectant, early weaning and movement to a hospital pen, or a rubber mat to lie on in the farrowing crate. Close observation and appropriate care of sows especially around the time of farrowing should keep the incidence of shoulder ulcers low in the pork industry

Lithium, sodium and potassium enolate aggregates and monomers: syntheses and structures

\ua9 2024 The Royal Society of Chemistry. In this Article, we report the syntheses and comparative structural studies of lithium, sodium, and potassium anthracen-9-yl enolates, as their aggregates (Li, Na: hexamer; K: tetramer) and ligand-stabilized monomers (for Li and Na). The monomers add new members to the rare collection of group-1 metal monomeric enolates. Moreover, the series covers different group-1 metal cations (Li+, Na+ and K+) and aggregate sizes, allowing comparative structural studies to elucidate how the metal identity and aggregate size influence the enolate structure

Rationale, design and methods of the Study of Work and Pain (SWAP): a cluster randomised controlled trial testing the addition of a vocational advice service to best current primary care for patients with musculoskeletal pain (ISRCTN 52269669)

Background Musculoskeletal pain is a major contributor to short and long term work absence. Patients seek care from their general practitioner (GP) and yet GPs often feel ill-equipped to deal with work issues. Providing a vocational case management service in primary care, to support patients with musculoskeletal problems to remain at or return to work, is one potential solution but requires robust evaluation to test clinical and cost-effectiveness. Methods/Design This protocol describes a cluster randomised controlled trial, with linked qualitative interviews, to investigate the effect of introducing a vocational advice service into general practice, to provide a structured approach to managing work related issues in primary care patients with musculoskeletal pain who are absent from work or struggling to remain in work. General practices (n = 6) will be randomised to offer best current care or best current care plus a vocational advice service. Adults of working age who are absent from or struggling to remain in work due to a musculoskeletal pain problem will be invited to participate and 330 participants will be recruited. Data collection will be through patient completed questionnaires at baseline, 4 and 12 months. The primary outcome is self-reported work absence at 4 months. Incremental cost-utility analysis will be undertaken to calculate the cost per additional QALY gained and incremental net benefits. A linked interview study will explore the experiences of the vocational advice service from the perspectives of GPs, nurse practitioners (NPs), patients and vocational advisors. Discussion This paper presents the rationale, design, and methods of the Study of Work And Pain (SWAP) trial. The results of this trial will provide evidence to inform primary care practice and guide the development of services to provide support for musculoskeletal pain patients with work-related issues. Trial registration Current Controlled Trials ISRCTN52269669

The influence of 'significant others' on persistent back pain and work participation: a qualitative exploration of illness perceptions

Background Individual illness perceptions have been highlighted as important influences on clinical outcomes for back pain. However, the illness perceptions of 'significant others' (spouse/partner/close family member) are rarely explored, particularly in relation to persistent back pain and work participation. The aim of this study was to initiate qualitative research in this area in order to further understand these wider influences on outcome. Methods Semi-structured interviews based on the chronic pain version of the Illness Perceptions Questionnaire-Revised were conducted with a convenience sample of UK disability benefit claimants, along with their significant others (n=5 dyads). Data were analysed using template analysis. Results Significant others shared, and perhaps further reinforced, claimants' unhelpful illness beliefs including fear of pain/re-injury associated with certain types of work and activity, and pessimism about the likelihood of return to work. In some cases, significant others appeared more resigned to the permanence and negative inevitable consequences of the claimant's back pain condition on work participation, and were more sceptical about the availability of suitable work and sympathy from employers. In their pursuit of authenticity, claimants were keen to stress their desire to work whilst emphasising how the severity and physical limitations of their condition prevented them from doing so. In this vein, and seemingly based on their perceptions of what makes a 'good' significant other, significant others acted as a 'witness to pain', supporting claimants' self-limiting behaviour and statements of incapacity, often responding with empathy and assistance. The beliefs and responses of significant others may also have been influenced by their own experience of chronic illness, thus participants lives were often intertwined and defined by illness. Conclusions The findings from this exploratory study reveal how others and wider social circumstances might contribute both to the propensity of persistent back pain and to its consequences. This is an area that has received little attention to date, and wider support of these findings may usefully inform the design of future intervention programmes aimed at restoring work participation

Punishment Feedback Impairs Memory and Changes Cortical Feedback-Related Potentials During Motor Learning

© Copyright © 2020 Hill, Stringer, Waddell and Del Arco. Reward and punishment have demonstrated dissociable effects on motor learning and memory, which suggests that these reinforcers are differently processed by the brain. To test this possibility, we use electroencephalography to record cortical neural activity after the presentation of reward and punishment feedback during a visuomotor rotation task. Participants were randomly placed into Reward, Punishment, or Control groups and performed the task under different conditions to assess the adaptation (learning) and retention (memory) of the motor task. These conditions featured an incongruent position between the cursor and the target, with the cursor trajectory, rotated 30° counterclockwise, requiring the participant to adapt their movement to hit the target. Feedback based on error magnitude was provided during the Adaptation condition in the form of a positive number (Reward) or negative number (Punishment), each representing a monetary gain or loss, respectively. No reinforcement or visual feedback was provided during the No Vision condition (retention). Performance error and event-related potentials (ERPs) time-locked to feedback presentation were calculated for each participant during both conditions. Punishment feedback reduced performance error and promoted faster learning during the Adaptation condition. In contrast, punishment feedback increased performance error during the No Vision condition compared to Control and Reward groups, which suggests a diminished motor memory. Moreover, the Punishment group showed a significant decrease in the amplitude of ERPs during the No Vision condition compared to the Adaptation condition. The amplitude of ERPs did not change in the other two groups. These results suggest that punishment feedback impairs motor retention by altering the neural processing involved in memory encoding. This study provides a neurophysiological underpinning for the dissociative effects of punishment feedback on motor learning