Fish oil rich in eicosapentaenoic acid and docosahexaenoic acid in sow diets modifies oxylipins and immune indicators in colostrum and milk

Colostrum and milk are the first nutrient sources for newborn piglets. In addition, n-3 fatty acids (FAs) and their oxygenated derivatives (oxylipins) have the capacity to modulate immune components. The aim of the current study was to include a fish oil rich in eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in sow diets to promote an increase of anti-inflammatory molecules in colostrum and milk to benefit piglets. Thirty-six sows were randomly assigned from insemination to the end of lactation to either a control diet with animal fat (15 g/kg in gestation and 30 g/kg in lactation) or an n-3 diet in which animal fat was totally (gestation) or half (lactation) replaced by an equivalent amount of solid fish oil. Performance of sows and piglets was monitored during the study. Colostrum and milk samples were obtained after the birth of the first piglet and at weaning, respectively. From all samples (n = 18 per treatment), FAs were quantified by gas chromatography and immunoglobulins and cytokines by ELISA. Three samples per treatment were randomly selected to analyse oxylipin composition by liquid chromatography-tandem mass spectrometry. In colostrum and in milk, the n-3 FA (P = 0.020 and P < 0.001), particularly EPA (P < 0.001 and P < 0.001) and DHA (P < 0.001 and P < 0.001), and also their oxygenated derivatives were increased in samples from sows fed n-3 diet. Fish oil had no effect on immunoglobulin concentrations, but reduced tumour necrosis factor α (TNFα) (P = 0.011) and a tendency to reduce interleukin 10 (IL10) (P = 0.059) were observed in milk. In conclusion, fish oil in sow diets increased n-3 FA, particularly EPA and DHA, and their oxygenated derivatives in colostrum and milk, reducing TNFα and IL10 in milk.info:eu-repo/semantics/publishedVersio

Optimization of Rear Point Contact Geometry by Means of 3-D Numerical Simulation

Abstract In this work three-dimensional (3-D) numerical simulations, validated by the experimental measurements of a reference cell, have been performed to optimize the rear contact geometry of a PERC-type solar cell, featuring a high sheet resistance (140 Ω/sq) phosphorus-doped emitter and a front-side metallization with narrow and highly-conductive electro-plated copper lines (40 μm wide) on lowly resistive Ti contacts. The simulation results show that an optimization of the rear point contact design potentially leads to an efficiency improvement of 0.68%abs compared to the reference cell

Biomarcadores conductuales de bovinos del sistema doble propósito

The importance of behavioral and physiological biomarkers and their effects on the dairy production of dual purpose cattle was evaluated through the collection and analysis of the primary information. The database maintained by the University of the Amazon, the National University of Colombia, and SCIELO, was analyzed using the keywords: animal welfare, ethology and bovine behavior. It was observed that the activities to which the cows are subjected in dairy production lead to an inevitable stress for the animal due to the conditions of the system, negatively affecting the production, specifically the quantity and quality of milk produced (Total solids, fats and proteins). Greater knowledge regarding animal welfare will contribute to a better understanding of the behavior of dual purpose cattle in dairy production, subject to different management conditions. In this sense, ethology becomes a powerful tool that helps to understand how these animals perceive their environment.Se evaluó a través de la recopilación y análisis de la información primaria, la importancia de los biomarcadores conductuales, fisiológicos y sus efectos en la producción lechera de bovinos doble propósito. Se analizó la base de datos que mantiene la Universidad de la Amazonia, la Universidad Nacional de Colombia, y SCIELO, usando las palabras clave: bienestar animal, etología y comportamiento bovino. Se observó que las actividades a las que son sometidas las vacas en producción lechera conllevan un estrés inevitable para el animal debido a las condiciones mismas del sistema, afectando negativamente la producción, específicamente la cantidad y calidad de leche producida (Solidos totales, grasas y proteínas). Un mayor conocimiento en lo que se refiere a bienestar animal contribuirá al mejor entendimiento de la conducta del ganado doble propósito en producción lechera, sometido a diferentes condiciones de manejo. En este sentido la etología se convierte en una herramienta poderosa que ayuda a comprender cómo perciben estos animales su entorno

May Measurement Month 2017: an analysis of blood pressure screening in Spain-Europe.

May Measurement Month 2017 is a global initiative aimed at raising awareness of high blood pressure (BP) and to act as a temporary solution to the lack of screening programs worldwide, in which Spain participated actively. The primary objective was to raise awareness and increase control of BP in Spain. An opportunistic cross-sectional survey of volunteers aged ≥18 was set up in May 2017. Following the design of the International Society of Hypertension, data were collected from the 17 autonomous communities in which Spain is divided, mainly in community pharmacies, primary care centres and some hypertension (HT) units, and cardiovascular departments in hospitals. No additional training of volunteers was necessary. A total of 3849 individuals were screened. After multiple imputation, our data showed that 1923 (50.0%) had HT. In those not receiving antihypertensive medication, 17.5% were hypertensives, in individuals receiving antihypertensive medication, 33.9% had uncontrolled BP. May Measurement Month 2017 was the largest BP screening campaign undertaken in Spain. In total, 17.5% of people with HT did not receive medication. One-third of hypertensive participants receiving treatment did not have their BP controlled. These results confirm that an opportunistic screening can identify a significant number of subjects with and untreated and inadequately treated BP

t(6;20)(q13;q12) LMBRD1/CHD6

Short communication on t t(6;20)(q13;q12) LMBRD1/CHD6, with data on clinics, and the genes implicated

A search and retrieval framework for the management of copyrighted audiovisual content

This paper presents a search and retrieval framework that enables the management of Intellectual Property in the World Wide Web. This twofold framework helps users to detect digital rights infringements of their copyrighted content. In order to detect possible copyright infringments, first the system crawls the Web to search replicas of user’s images, and later evaluates if the copies have been taken respecting the terms stated by the owner. On the other hand, this framework also helps users in finding something interesting in the Web. It will provide copyrighted content to users according to their preferences and to intellectual property rights integrating search and retrieval with digital rights management tools

Garantismo y crisis de la justicia

Esta obra representa una importante reflexión teórica producto de la labor investigativa de sus autores, en torno a uno de los problemas de mayor actualidad en la sociedad contemporánea, cual es, la tensión permanente que se presenta entre la necesidad que tiene el Estado de garantizar un orden o control social y al mismo tiempo, la exigencia actual de la garantía y protección de los derechos fundamentales