Analysis of Different Methodologies to Calculate Bouguer Gravity Anomalies in the Argentine Continental Margin

We have tested and used two methods to determine the Bouguer gravity anomaly in the area of the Argentine continental margin. The first method employs the relationship between the topography and gravity anomaly in the Fourier transform domain using Parker’s expression for different orders of expansion. The second method computes the complete Bouguer correction (Bullard A, B and C) with the Fortran code FA2BOUG2. The Bouguer slab correction (Bullard A), the curvature correction (Bullard B) and the terrain correction (Bullard C) are computed in several zones according to thedistances between the topography and the calculation point. In each zone, different approximations of the gravitationalattraction of rectangular or conic prisms are used according to the surrounding topography. Our calculations show that the anomaly generated by the fourth order in Parker’s expansion is actually compatible with the traditional Bouguer anomaly calculated with FA2BOUG, and that higher orders do not introduce significant changes. The comparison reveals that the difference between both methods in the Argentine continental margin has a quasi bimodal statistical distribution. The main disadvantage in using routines based on Parker's expansion is that an average value of the topography is needed for the calculation and, as the margin has an abrupt change of the topography in the continental slope area, it causes a bimodal distribution. It is worth noticing that, as expected, the most important differences between both methods are located over the continental slope both in complex structures such as part of the shared margin, as well as in isolated points where there are contributions from short wavelength or rugged topography.Fil: Pedraza de Marchi, Ana Carolina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de la Plata. Facultad de Ciencias Astronómicas y Geofísicas; ArgentinaFil: Ghidella, Marta E.. Ministerio de Relaciones Exteriores, Comercio Interno y Culto. Dirección Nacional del Antártico. Instituto Antártico Argentino; ArgentinaFil: Tocho, Claudia. Universidad Nacional de la Plata. Facultad de Ciencias Astronómicas y Geofísicas; Argentin

Mfd Protects Against Oxidative Stress in Bacillus Subtilis Independently of its Canonical Function in DNA Repair

Background: Previous reports showed that mutagenesis in nutrient-limiting conditions is dependent on Mfd in Bacillus subtilis. Mfd initiates one type of transcription-coupled repair (TCR); this type of repair is known to target bulky lesions, like those associated with UV exposure. Interestingly, the roles of Mfd in repair of oxidative-promoted DNA damage and regulation of transcription differ. Here, we used a genetic approach to test whether Mfd protected B. subtilis from exposure to two different oxidants. Results: Wild-type cells survived tert-butyl hydroperoxide (t-BHP) exposure significantly better than Mfd-deficient cells. This protective effect was independent of UvrA, a component of the canonical TCR/nucleotide excision repair (NER) pathway. Further, our results suggest that Mfd and MutY, a DNA glycosylase that processes 8-oxoG DNA mismatches, work together to protect cells from lesions generated by oxidative damage. We also tested the role of Mfd in mutagenesis in starved cells exposed to t-BHP. In conditions of oxidative stress, Mfd and MutY may work together in the formation of mutations. Unexpectedly, Mfd increased survival when cells were exposed to the protein oxidant diamide. Under this type of oxidative stress, cells survival was not affected by MutY or UvrA. Conclusions: These results are significant because they show that Mfd mediates error-prone repair of DNA and protects cells against oxidation of proteins by affecting gene expression; Mfd deficiency resulted in increased gene expression of the OhrR repressor which controls the cellular response to organic peroxide exposure. These observations point to Mfd functioning beyond a DNA repair factor in cells experiencing oxidative stress

The invertebrate Caenorhabditis elegans biosynthesizes ascorbate.

l-Ascorbate, commonly known as vitamin C, serves as an antioxidant and cofactor essential for many biological processes. Distinct ascorbate biosynthetic pathways have been established for animals and plants, but little is known about the presence or synthesis of this molecule in invertebrate species. We have investigated ascorbate metabolism in the nematode Caenorhabditis elegans, where this molecule would be expected to play roles in oxidative stress resistance and as cofactor in collagen and neurotransmitter synthesis. Using high-performance liquid chromatography and gas-chromatography mass spectrometry, we determined that ascorbate is present at low amounts in the egg stage, L1 larvae, and mixed animal populations, with the egg stage containing the highest concentrations. Incubating C. elegans with precursor molecules necessary for ascorbate synthesis in plants and animals did not significantly alter ascorbate levels. Furthermore, bioinformatic analyses did not support the presence in C. elegans of either the plant or the animal biosynthetic pathway. However, we observed the complete (13)C-labeling of ascorbate when C. elegans was grown with (13)C-labeled Escherichia coli as a food source. These results support the hypothesis that ascorbate biosynthesis in invertebrates may proceed by a novel pathway and lay the foundation for a broader understanding of its biological role

Children’s narratives on migrant refugees: a practice of global citizenship

Globalisation has brought about great social and economic impact, as well as great challenges. Major developments have taken place in the mobility of capital and, to a lesser extent, of goods; not so in the mobility of people seeking asylum due to persecution and war. This article approaches the phenomenon of migration, particularly of refugees, as learning content for early childhood. The research is presented from a qualitative approach based on the results of a project on this topic implemented in a rural school in Spain. The results of the data analysis reveal that children attribute external reasons, of survival, to the refugees’ forced departure from their country of origin. The children’s imaginary reproduces the social construction of adults on the status and situation of refugees, and they also show a critical attitude towards the violation of human rights and the abuse of fellow children. Finally, respect, cultural empathy and social commitment in the face of injustice are presented as fundamental values for education in global citizenship from the earliest stages of schooling

Universal rapidity scaling of entanglement entropy inside hadrons from conformal invariance

When a hadron is probed at high energy, a non-trivial quantum entanglement entropy inside the hadron emerges due to the lack of complete information about the hadron wave function extracted from this measurement. In the high energy limit, the hadron becomes a maximally entangled state, with a linear dependence of entanglement entropy on rapidity, as has been found in a recent analysis based on parton description. In this Letter, we use an effective conformal field theoretic description of hadrons on the lightcone to show that the linear dependence of the entanglement entropy on rapidity found in parton description is a general consequence of approximate conformal invariance and does not depend on the assumption of weak coupling. Our result also provides further evidence for a duality between the parton and string descriptions of hadrons.Comment: 5 pages, 1 figur