53 research outputs found

    Definition of industrial enterprises development conditions and new approaches to resources using

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    The article presents an analysis of the conditions required to provide the industrial sustainable development in the digital transformations. A study has been carried out that determines the complementary assets role in modelling the enterprises development management processes operating in the context of ecosystem interactions in order to determine the properties of complementary interactions that contribute to the further value formation as a result of controlled changes in interactions by activity type or by product type. It is proposed to establish interactions by economic activity types presented in the Russian Classification of Economic Activities, which will allow us to determine the maximum possible profitability as a condition of complementarity from the main activity type and additional incoming types. The complementarity signs, which make it possible to achieve the required development and sustainability level in the ecosystem, have been determined

    Wavelets: mathematics and applications

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    The notion of wavelets is defined. It is briefly described {\it what} are wavelets, {\it how} to use them, {\it when} we do need them, {\it why} they are preferred and {\it where} they have been applied. Then one proceeds to the multiresolution analysis and fast wavelet transform as a standard procedure for dealing with discrete wavelets. It is shown which specific features of signals (functions) can be revealed by this analysis, but can not be found by other methods (e.g., by the Fourier expansion). Finally, some examples of practical application are given (in particular, to analysis of multiparticle production}. Rigorous proofs of mathematical statements are omitted, and the reader is referred to the corresponding literature.Comment: 16 pages, 5 figures, Latex, Phys. Atom. Nuc

    Designing a model of interaction of economic resources in the quantization conditions of economic area

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    © 2015, Mediterranean Center of Social and Educational Research. All rights reserved. The article aims to develop a methodology for investigating cyclic recurrence of economic phenomena in the quantization conditions of the modern economy. The article highlights the quantization levels and the adaptive possibilities of stabilizing the economic processes and phenomena. The authors have developed a target model of interaction of economic resources in the quantization conditions, allowing to identify the type and stages of interaction at the current time. The results of the research have a wide range of applications in the development of specific manifestations of economic regularities by researchers, practicians working in the field of economics

    Charged particle production in the Pb+Pb system at 158 GeV/c per nucleon

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    Charged particle multiplicities from high multiplicity central interactions of 158 GeV/nucleon Pb ions with Pb target nuclei have been measured in the central and far forward projectile spectator regions using emulsion chambers. Multiplicities are significantly lower than predicted by Monte Carlo simulations. We examine the shape of the pseudorapidity distribution and its dependence on centrality in detail.Comment: 17 pages text plus 12 figures in postscript 12/23/99 -- Add TeX version of sourc

    Nonlinear thermo-optical properties of two-layered spherical system of gold nanoparticle core and water vapor shell during initial stage of shell expansion

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    Nonlinear thermo-optical properties of two-layered spherical system of gold nanoparticle core and water vapor shell, created under laser heating of nanoparticle in water, were theoretically investigated. Vapor shell expansion leads to decreasing up to one to two orders of magnitude in comparison with initial values of scattering and extinction of the radiation with wavelengths 532 and 633 nm by system while shell radius is increased up to value of about two radii of nanoparticle. Subsequent increasing of shell radius more than two radii of nanoparticle leads to rise of scattering and extinction properties of system over initial values. The significant decrease of radiation scattering and extinction by system of nanoparticle-vapor shell can be used for experimental detection of the energy threshold of vapor shell formation and investigation of the first stages of its expansion

    Ритмическая транскраниальная магнитная стимуляция в терапии нейропатической боли, сопровождающейся коморбидной депрессией: обзор эффективных параметров лечебных протоколов

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    Neuropathic pain affects 7 % of the general population worldwide, it is often resistant to analgesic treatments and is complicated with depressive states in 57–65 % of this patients’ cohort. Ongoing research of current therapeutic approaches, including repetitive transcranial magnetic stimulation (rTMS) use in neuropathic pain and depression, grants new data about the details of treatment protocols’ designs. The aim of our literature review was to evaluate those parameters of the treatment protocols which proved significant efficacy in the management of the neuropathic pain with comorbid depression.Focusing on the Scopus, Elsevier and PubMed databases search, we have found 639 peer‑review articles. 23 studies have been included into the data analysis, whereas others were excluded based on their heterogeneous study design. Across the data analysis we evaluated such rTMS parameters as the type of a coil, type of stimulation area, locus of gained evoked motor potential, amplitude of stimulation, duration of session, frequency/number of sessions per day/month, tie duration between sessions, number and frequency of trains, amount and frequency of pulses containing and efficacy of treatment. Those studies that performed repetitive transcranial magnetic stimulation using the figure‑of‑8 coil over the M1 brain area, for 10 or more daily sessions with duration from 7 up to 40 minutes, of 10–20 Hz frequency, intensity 80–90 % of resting motor threshold and total pulses number over 1500 per session demonstrated the greater efficacy in pain level decrease and depression scores reduction among neuropathic pain patients with comorbid depression. Conducting an additional maintenance phase of treatment prolonged the therapeutic effect of the course.Based on the data review, the parameters of the most efficient rTMS protocols’ designs in management of patients with neuropathic pain and comorbid depression have been revealed. Further research requires investigation of other promising indicators of rTMS efficacy use in neuropathic pain with comorbid depression, such as stimulation over multiple brain areas, the duration/timing of additional maintenance phase of treatment, and the figure‑of‑8 coil orientation options.По общемировым данным, нейропатическая боль встречается у 7 % населения и в 57–65 % случаев сопровождается коморбидной депрессией, что, в свою очередь, усугубляет течение болезни и ухудшает качество жизни пациентов. Ритмическая транскраниальная магнитная стимуляция (рТМС) представляет собой неинвазивный нефармакологический метод терапии депрессии,  также способный помочь пациентам облегчить восприятие нейропатической боли. Представлен обзор результатов применения протоколов рТМС, продемонстрировавших эффективность в терапии клинических состояний, сопровождающихся нейропатической болью с коморбидной депрессией.Исследуя базы данных Scopus, Elsevier и PubMed , мы обнаружили 639 статей, из которых в соответствии с критериями включения были отобраны 23. Оценке подверглись данные о клинической эффективности рТМС в терапии нейропатической боли и коморбидной депрессии в зависимости от параметров протокола стимуляции, включая тип катушки, целевую зону мозга, продолжительность сеанса, частоту/количество сеансов в день/месяц, а также межсеансовые интервалы, число и частоту импульсов.Протоколы, показавшие наибольшую эффективность, включали такие параметры, как использование катушки в форме восьмерки, направленной на первичную моторную зону (M1), применение рТМС в течение не менее 10 ежедневных сеансов, использование высокочастотной стимуляции (10–20 Гц) с интенсивностью 80–90 % от порога моторного ответа, с длительностью сессии от 7 до 40 мин и с общим количеством импульсов не менее 1500 за сеанс. Проведение дополнительной поддерживающей фазы лечения продлевало терапевтический эффект курса.Результаты анализа данных литературы предполагают, что определенная комбинация параметров стимуляции может быть более эффективной для терапии нейропатической боли, сопровождающейся коморбидной депрессией, тем самым открывая новые возможности терапии для пациентов с резистентными состояниями, плохо поддающимися фармакологической коррекции. Рассмотрение параметров протоколов рТМС выявило необходимость дальнейшего изучения метода в лечении указанных клинических состояний не только в рамках репликации данных, но и для анализа таких дополнительных параметров, как последовательная или одновременная стимуляция нескольких областей мозга, угол поворота катушки, а также для уточнения времени поддерживающей фазы стимуляции

    Роль ультразвуковой оценки коэффициента массы селезенки в динамике наблюдения детей с хронической формой ВЭБ-инфекцией

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    Purpose of the study: to show the significance of ultrasound diagnostics in assessing the dynamics of the spleen mass coefficient in children of various age against the background of a chronic form of EBV virus.Materials and methods. The study was performed on 146 children aged 3 to 18 years suffering from chronic EBV virus. Depending on age, the children were divided into 3 groups. Group 1 included 63 patients aged 3 to 7 years; Group 2 consisted of 28 children aged 8 to 11 years; Group 3 included 55 children aged 12 to 18 years. The clinical, laboratory and ultrasound examination was conducted including ultrasound of the spleen with the further determination of its mass coefficient (SMC).Results. In the acute period of EBV virus, children of all age groups revealed an increase in SMC, while the maximum increase was observed in children aged 3 to 7 years and amounted to 6,88. Against the background of a complete clinical and laboratory recovery in this age group, the SMC remained at the level of 4.66 and did not reach the average values of healthy children of the same age. The follow-up dynamics for 15–18 months demonstrated the normalization of the SMC to the average values of healthy patients in accordance with their age (in children aged 12 years and older).Findings. Children in the age group from 3 to 7 years old had the maximum value of the spleen mass coefficient, both in the acute period and after complete clinical and laboratory recovery. The use of ultrasound technique with the assessment of the spleen mass coefficient in the chronic course of EBV virus allows expanding and determining the children contingent for further dynamic monitoring for prevention of possible complications.Цель исследования: показать значимость ультразвуковой диагностики  в оценке динамики коэффициента массы селезенки у детей различных возрастных групп на фоне хронической формы ВЭБ - инфекции.Материалы и методы. В исследование включили 146 детей в возрасте от 3 до 18 лет с хронической формой ВЭБ - инфекции. В зависимости от возраста, дети были разделены на 3 группы. В 1-ю группу вошло 63 пациента от 3 до 7 лет; 2 – ю группу составили 28 детей с 8 до 11 лет; 3 – ю группу - 55 детей от 12 до 18 лет. Проводили клиническое, лабораторное и ультразвуковое обследование, включая ультразвуковое исследование селезенки с определением коэффициента массы (КМС).Результаты. В остром периоде ВЭБ инфекции дети всех возрастных групп имели увеличение КМС, при этом максимальное увеличение отмечалось у детей от 3 до 7 лет и колебалось в диапазоне от 4,9 до 9,2. При наличии полного клинико-лабораторного выздоровления у данного возрастного контингента КМС оставался на уровне 4,2-5,8 и не достигал средних значений здоровых детей данного возраста. Динамика наблюдения в течение 15-18 месяцев выявляла нормализацию КМС до средневозрасных значений здоровых пациентов у детей 12 лет и старше.Выводы. Дети в группе от 3 до 7 лет имели максимальное значение коэффициента массы селезенки, как в остром периоде, так и после полного клинико - лабораторного выздоровления. Применение ультразвуковой методики с оценкой коэффициента массы селезенки при хроническом течении ВЭБ-инфекции позволяет расширить и определить контингент детей для дальнейшего динамического наблюдения с целью профилактики возможных осложнений

    Erratum to: 36th International Symposium on Intensive Care and Emergency Medicine

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    [This corrects the article DOI: 10.1186/s13054-016-1208-6.]
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