Case Studies of the Attainment of Insight in Dream Sessions: Replication and Extension

To replicate and extend the Hill, Knox, et al. (2007) case study of a client who attained insight in one session of dream work, the authors examined two additional single-session cases: one in which a client gained insight and another in which a client did not. The observations across all three cases suggest that the two clients who acquired insight had positive attitudes toward dreams; were motivated and involved in session; and were nonresistant, trusting, and affectively present but not overwhelmed. The client who did not gain insight questioned the value of dreams and was resistant, untrusting, andf emotionally overwhelmed. Therapist adherence and competence using the dream model, ability to manage countertransference, and effective use of probes for insight distinguished the therapists whose clients gained insight from the therapist whose client did not

Using Diatonic Tendencies As A Harmonic Technique

This Thesis is designed to show that the natural tendencies of the diatonic scale dictate a simple technique of harmony, technique herein presented has as its foundation already accepted principles and factors. In spite of the simplicity of this technique, it will be shown to be more efficient than some techniques of harmony commonly used. In this work the concern will be with the music of the eighteenth and nineteenth centuries, commonly called the harmonic period. The materials used are the major and minor scales of this period, and the chords derived there from. The presentation of the technique will be first, by setting forth a principle from which rules will be extracted; second, by examples that will show practical application of these rules. A comparison of the technique with that of Walter Piston, will be made to show the efficiency of this technique in reaching the common objective. Supporting information from other recognized theorists will be used. Piston\u27s technique is used for comparison, because his text was used in the harmony classes at Prairie View Agricultural and Mechanical College when I began this paper, and it follows the line of the most conventional technique. Finally, a comparative study by analysis will be made of a Bach Chorale, using the methods of analysis of Donald Tweedy, Walter Piston, and that of the Diatonic Technique

Polo like kinase 2 tumour suppressor and cancer biomarker: new perspectives on drug sensitivity/resistance in ovarian cancer

The polo-like kinase PLK2 has recently been identified as a potential theranostic marker in the management of chemotherapy sensitive cancers. The methylation status of the PLK2 CpG island varies with sensitivity to paclitaxel and platinum in ovarian cancer cell lines. Importantly, extrapolation of these in vitro data to the clinical setting confirms that the methylation status of the PLK2 CpG island predicts outcomes in patients treated with carboplatin and paclitaxel chemotherapy. A second cell cycle regulator, p57Kip2, is also subject to epigenetic silencing in carboplatin resistance in vitro and in vivo, emphasising that cell cycle regulators are important determinants of sensitivity to chemotherapeutic agents and providing insights into the phenomenon of collateral drug sensitivity in oncology. Understanding the mechanistic basis and identification of robust biomarkers to predict collateral sensitivity may inform optimal use of chemotherapy in patients receiving multiple lines of treatment

A Millikelvin Scanned Probe for Measurement of Nanostructures

We demonstrate a scanning force microscope, based upon a quartz tuning fork, that operates below 100 mK and in magnetic fields up to 6 T. The microscope has a conducting tip for electrical probing of nanostructures of interest, and it incorporates a low noise cryogenic amplifier to measure both the vibrations of the tuning fork and the electrical signals from the nanostructures. At millikelvin temperatures the imaging resolution is below 1 um in a 22 um x 22 um range, and a coarse motion provides translations of a few mm. This scanned probe is useful for high bandwidth measurement of many high impedance nanostructures on a single sample. We show data locating an SET within an array and measure its coulomb blockade with a sensitivity of 2.6 x 10^-5 e/Hz^1/2.Comment: 5 pages, 5 figures, submitted to RS

Housing policy: a more coherent approach

Our current housing crisis has many facets. There are too few homes for everyone, those there are can be unaffordable, and intergeneration inequalities in housing costs and wealth are more pronounced that at any other time in the postwar era. Meanwhile home ownership is falling, while the insecure private rented sector has doubled in size since the turn of the century – and now accommodates almost 20% of households

On the Change in Archivability of Websites Over Time

As web technologies evolve, web archivists work to keep up so that our digital history is preserved. Recent advances in web technologies have introduced client-side executed scripts that load data without a referential identifier or that require user interaction (e.g., content loading when the page has scrolled). These advances have made automating methods for capturing web pages more difficult. Because of the evolving schemes of publishing web pages along with the progressive capability of web preservation tools, the archivability of pages on the web has varied over time. In this paper we show that the archivability of a web page can be deduced from the type of page being archived, which aligns with that page's accessibility in respect to dynamic content. We show concrete examples of when these technologies were introduced by referencing mementos of pages that have persisted through a long evolution of available technologies. Identifying these reasons for the inability of these web pages to be archived in the past in respect to accessibility serves as a guide for ensuring that content that has longevity is published using good practice methods that make it available for preservation.Comment: 12 pages, 8 figures, Theory and Practice of Digital Libraries (TPDL) 2013, Valletta, Malt

Laughing Song

https://digitalcommons.library.umaine.edu/mmb-vp/4636/thumbnail.jp

Protection of mice against cancer by immunization with membranes but not purified virions from virus infected cancer cells.

The life span of C57/Bl mice inoculated with Lewis lung carcinoma cells was prolonged if the mice were pre-immunized with membranes from these cells infected in vitro with influenza virus. Likewise, BALB/c mice were protected against the malignant tumour WEHI-11 by prior immunization with extracts of cultured WEHI-11 cells which had been infected with influenza virus or Semiliki Forest virus (SFV). Partially purified SFV grown in WEHI-11 cells also protected mice from cancer grafts but neither highly purified SFV nor the glycoprotein from the envelope of this virus protected the mice. It is concluded that SFV-induced immunopotentiation against cancer is not due to covalent linkage of tumour specific transplantation antigen (TSTA) to viral envelope protein but more probably is due to the apposition of viral glycoprotein and cellular TSTA in the plasma membrane of the cancer cell

Uncertainty and Reasonable Assurance: Why We Need to Teach Regulators to Focus on Uncertainty in Risk Assessment and Risk Management

The rationality of regulatory decisions is inextricably linked to an explicit representation of the uncertainty underlying scientific predictions. The level of coverage of uncertainty in training programs on risk assessment and risk management developed by the EPA is examined in light of the above thesis. Using the EPA's Office Of Drinking Water's Workshops on Assessment and Management of Drinking Water Contamination (EPA, 1988) as an example, concepts for formalizing consideration of uncertainty are presented. A case study on the risks from radon in drinking water is developed to illustrate the recommended level of coverage of uncertainty in EPA training programs.Master of Science in Public Healt

Whole-genome sequencing shows that patient-to-patient transmission rarely accounts for acquisition of Staphylococcus aureus in an intensive care unit

BACKGROUND  Strategies to prevent Staphylococcus aureus infection in hospitals focus on patient-to-patient transmission. We used whole-genome sequencing to investigate the role of colonized patients as the source of new S. aureus acquisitions, and the reliability of identifying patient-to-patient transmission using the conventional approach of spa typing and overlapping patient stay. METHODS Over 14 months, all unselected patients admitted to an adult intensive care unit (ICU) were serially screened for S. aureus. All available isolates (n = 275) were spa typed and underwent whole-genome sequencing to investigate their relatedness at high resolution. RESULTS Staphylococcus aureus was carried by 185 of 1109 patients sampled within 24 hours of ICU admission (16.7%); 59 (5.3%) patients carried methicillin-resistant S. aureus (MRSA). Forty-four S. aureus (22 MRSA) acquisitions while on ICU were detected. Isolates were available for genetic analysis from 37 acquisitions. Whole-genome sequencing indicated that 7 of these 37 (18.9%) were transmissions from other colonized patients. Conventional methods (spa typing combined with overlapping patient stay) falsely identified 3 patient-to-patient transmissions (all MRSA) and failed to detect 2 acquisitions and 4 transmissions (2 MRSA). CONCLUSIONS Only a minority of S. aureus acquisitions can be explained by patient-to-patient transmission. Whole-genome sequencing provides the resolution to disprove transmission events indicated by conventional methods and also to reveal otherwise unsuspected transmission events. Whole-genome sequencing should replace conventional methods for detection of nosocomial S. aureus transmission