624 research outputs found

    a review

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    Introduction: eHealth and mHealth are technologies that allow services to be extended closer to patients, in pursuit of the objectives of Health 2020: a European policy framework and strategy for the 21st century and of the Global Strategy on Human Resources for Health: workforce 2030. As Europe faces increased demand for health services due to ageing populations, rising patient mobility, and a diminishing supply of health workers caused by retirement rates that surpass recruitment rates, this paper illustrates how eHealth and mHealth can improve the delivery of services by the health workforce in response to increasing demands. Methods: Through a scoping literature review, the impact of eHealth/mHealth on the health workforce was assessed by examining how these technologies affect four dimensions of the performance of health professionals, according to the so-called AAAQ: availability, accessibility, acceptability, and quality. Results: Few high-quality studies were found. Most studies focused on the utilization of text messaging (SMS) for patient behavior change, and some examined the potential of mhealth to strengthen health systems. We also found some limited literature reporting effects on clinical effectiveness, costs, and patient acceptability; we found none reporting on equity and safety issues. Facilitators and barriers to the optimal utilization of eHealth and mHealth were identified and categorized as they relate to individuals, professional groups, provider organizations, and the institutional environment. Discussion: There are ongoing clinical trial protocols of largescale, multidimensional mHealth interventions, suggesting that the current limited evidence base will expand in coming years. The requirement for new digital skills for human resources for health (HRH) was observed as significant. This has implications for the education of health workers, the management of health services, policy-making, and research.publishersversionpublishe

    \u3ci\u3eN\u3c/i\u3e\u3csup\u3e5\u3c/sup\u3e-Phosphonoacetyl-L-ornithine (PALO): A convenient synthesis and investigation of influence on regulation of amino acid biosynthetic genes in \u3ci\u3eSaccharomyces cerevisiae\u3c/i\u3e

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    A scalable four-step synthesis of the ornithine transcarbamylase inhibitor N5-phosphonoacetyl-L-ornithine (PALO) is achieved through boroxazolidinone protection of ornithine. Investigations in the model organism Saccharomyces cerevisiae found that, in contrast to a previous report, PALO did not influence growth rate or expression of genes involved in arginine metabolism

    O conhecimento sobre o medicamento e literacia em saúde. Um estudo em adultos utentes de farmácias do concelho de Lisboa

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    Estudos recentes realizados nas farmácias portuguesas evidenciaram elevadas percentagens de indivíduos que não aderem à terapêutica. Em consequência, não controlam adequadamente o seu problema de saúde e geram desperdício do medicamento. A utilização do medicamento requer conhecimento, competências e motivação por parte do indivíduo/utilizador. A informação sobre o medicamento é disponibilizada de forma verbal e escrita, desconhecendo-se até hoje, na população portuguesa, em que medida as competências de literacia em saúde permitem a sua obtenção, o uso e a compreensão quando perante a necessidade de utilizar medicamentos. Foi objetivo do presente estudo a medição do conhecimento sobre o medicamento numa amostra de utentes de farmácia com idades compreendidas entre os 45 e os 64 anos, analisando de que forma está associado a competências de literacia em saúde. Realizou-se um estudo descritivo transversal com a colaboração voluntária de farmácias do concelho de Lisboa, que recolheram os dados mediante inquérito por entrevista quando o utente se encontrava na farmácia a adquirir a sua terapêutica. A amostra estudada foi constituída por 233 utentes com uma idade média de 57 anos (dp = 5,7), maioritariamente do género feminino, ativos, com uma escolaridade igual ou inferior ao 9.º ano e com hábitos gerais de leitura referindo ler frequentemente (26 por cento) ou muito frequentemente (30 por cento). Em média responderam corretamente a 10,48 perguntas num total de 13 (dp = 1,779), sendo este conhecimento independente do sexo (p = 0,791) e da idade (p = 0,131). O número de respostas corretas é, no entanto, maior quanto mais elevado o grau de escolaridade (p = 0,000), a categoria profissional exercida (p=0,000), os hábitos de leitura (p=0,000), o índice de compreensão de informação (p = 0,003), a intensidade de leitura de informação sobre saúde ou medicamento (p = 0,005), a facilidade de utilização do folheto informativo do medicamento (p = 0,027), a intensidade de cálculo (p = 0,018) e o tempo de utilização do medicamento (p = 0,047). Do conjunto de indicadores de literacia analisados, o grau de escolaridade, o índice de compreensão da informação transmitida pelos profissionais de saúde e a intensidade de leitura de materiais escritos relacionados com o medicamento ou saúde são os que mais contribuem para o conhecimento sobre o medicamento, embora se revelem fracamente preditivos do nível de conhecimento (r2 = 0,013). Evidencia-se neste estudo que o conhecimento que os indivíduos possuem sobre o medicamento é influenciado de forma positiva por competências de literacia em saúde. Em consequência, as intervenções que visam melhorar a utilização do medicamento e as estratégias de comunicação em saúde, tanto verbal como escrita, devem ter em consideração o nível de literacia em saúde da população.info:eu-repo/semantics/publishedVersio

    Design of a 3D printer head for additive manufacturing of sugar glass for tissue engineering applications

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    Additive manufacturing is now considered as a new paradigm that is foreseen to improve progress in many fields. The field of tissue engineering has been facing the need for tissue vascularization when producing thick tissues. The use of sugar glass as a fugitive ink to produce vascular networks through rapid casting may offer the key to vascularization of thick tissues produced by tissue engineering. Here, a 3D printer head capable of producing complex structures out of sugar glass is presented. This printer head uses a motorized heated syringe fitted with a custom made nozzle. The printer head was adapted to be mounted on a commercially available 3D printer. A mathematical model was derived to predict the diameter of the filaments based on the printer head feed rate and extrusion rate. Using a 1 mm diameter nozzle, the printer accurately produced filaments ranging from 0.3 mm to 3.2 mm in diameter. One of the main advantages of this manufacturing method is the self-supporting behaviour of sugar glass that allows the production of long, horizontal, curved, as well as overhanging filaments needed to produce complex vascular networks. Finally, to establish a proof of concept, polydimethylsiloxane was used as the gel matrix during the rapid casting to produce various “vascularized” constructs that were successfully perfused, which suggests that this new fabrication method can be used in a number of tissue engineering applications, including the vascularization of thick tissues
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