479 research outputs found
Squark Pair Production in the MSSM with Explicit CP Violation
We analyze effects of the CP-odd soft phases in the MSSM on the
pair-productions of colored superpartners in pp collisions at the LHC energies.
We find that, among all pair-production processes, those of the scalar quarks
in the first and second generations are particularly sensitive to the CP-odd
phases, more precisely, to the phases of the gluinos and neutralinos. We
compute pair-production cross sections, classify various production modes
according to their dependencies on the gluino and neutralino phases, perform a
detailed numerical analysis to determine individual as well as total cross
sections, and give a detailed discussion of EDM bounds. We find that
pair-productions of first and second generation squarks serve as a viable probe
of the CP violation sources in the gaugino sector of the theory even if
experiments cannot determine chirality, flavor and electric charge of the
squarks produced.Comment: 36 pp, 14 ps figures, 1 table, Corrected the cross sections; mild
changes in numerical results; conclusion unchange
An Exact Solution for Static Scalar Fields Coupled to Gravity in -Dimensions
We obtain an exact solution for the Einstein's equations with cosmological
constant coupled to a scalar, static particle in static, "spherically"
symmetric background in 2+1 dimensions.Comment: 9 pages. Replaced by a revised versio
A case of unusually located left ventricular myxoma: myxoma attached to the chordae tendinea of the mitral valve
Predictors of outcome for severely emotionally disturbed children in treatment
Despite general agreement that severely emotionally disturbed children and adolescents are an "at risk" group, and that ongoing evaluation and research into the effectiveness of services provided for them is important, very little outcome evaluation actually takes place. The absence of well-conducted and appropriately interpreted studies is particularly notable for day or residential treatment programs, which cater for the most severely emotionally disturbed youths. This thesis outlines the main areas of conceptual, pragmatic and methodological confusion and neglect which impede progress in research in this area. It argues for plurality of data analytic strategies and research designs. It then critically reviews the reported findings about the effectiveness of day and residential treatment in specialist facilities, and the predictors of good outcomes for this treatment type. This review confirms that there is very little to guide practice. Having argued for the legitimacy of its methods and the necessity to address basic questions, the thesis reports the results of a naturalistic study based on data accumulated during a decade-long evaluative research program taking place at Arndell Child and Adolescent Unit, Sydney. The study addresses the question of what child, family and treatment variables predict outcome for 159 children and adolescents treated at this facility from 1990 to 1999. Statistically significant results with large effect size were obtained. Among the most disturbed subgroup of forty three children, (a) psychodynamic milieu-based treatment was shown to be more effective than the “empirically-validated” cognitive-behavioural treatment which superseded it in 1996, and (b) children from step-families showed better outcome than those from other family structures. Furthermore, it was found for the study sample as a whole that severe school-based problem behaviours were associated with a limited trajectory of improvement in home-based problem behaviour. These results are discussed with regard to implications for treatment, research methodology, policy and further studies
Phytoplankton composition related to the environmental conditions in the coastal waters of the Gulf of Erdek
1545-1559Seasonal changes of phytoplankton communities in the coastal waters of the Gulf of Erdek from November 2006 to August 2008 were examined in relation to some environmental variables and 95 species from 6 different algae groups were identified. In addition, two species were recorded for the first time in the Turkish coastal waters and one species for the Sea of Marmara. The maximum total phytoplankton abundance (1.99 × 105 cells L-1) were observed in May 2008, with Pseudo-nitzschia sp. being the most dominant species of that month (1.52 × 105 cells L-1). Both the Bray-Curtis diversity index and the Euclidean distance indicated that the upper and lower water layers were separated from each other at the stations, and the Spearman’s rank-correlation and CCA analyses also showed that environmental variables affected the abundance of species. Furthermore, according to the CCA diagram, especially the temperature and dissolved oxygen had a bigger impact on the distribution of species. The Shannon-Wiener diversity index (Hʹ) values were low when Pseudo-nitzschia sp., Prorocentrum micans, Gymnodinium sp. and Prorocentrum scutellum were dominant over other species in the sampling period
Constraining Bosonic Supersymmetry from Higgs results and 8 TeV ATLAS multi-jets plus missing energy data
The collider phenomenology of models with Universal Extra Dimensions (UED) is
surprisingly similar to that of supersymmetric (SUSY) scenarios. For each
level-1 bosonic (fermionic) Kaluza-Klein (KK) state, there is a fermionic
(bosonic) analog in SUSY and thus UED scenarios are often known as bosonic
supersymmetry. The minimal version of UED (mUED) gives rise to a
quasi-degenerate particle spectrum at each KK-level and thus, can not explain
the enhanced Higgs to diphoton decay rate hinted by the ATLAS collaboration of
the Large Hadron Collider (LHC) experiment. However, in the non-minimal version
of the UED (nmUED) model, the enhanced Higgs to diphoton decay rate can be
easily explained via the suitable choice of boundary localized kinetic (BLK)
terms for higher dimensional fermions and gauge bosons. BLK terms remove the
degeneracy in the KK mass spectrum and thus, pair production of level-1 quarks
and gluons at the LHC gives rise to hard jets, leptons and large missing energy
in the final state. These final states are studied in details by the ATLAS and
CMS collaborations in the context of SUSY scenarios. We find that the absence
of any significant deviation of the data from the Standard Model (SM)
prediction puts a lower bound of about 2.1 TeV on equal mass excited quarks and
gluons.Comment: 19 page
Diagnostic and prognostic role of TFF3, Romo-1, NF-ĐşB and SFRP4 as biomarkers for endometrial and ovarian cancers: a prospective observational translational study
Purpose: This study aimed to evaluate trefoil factor 3 (TFF3), secreted frizzled-related protein 4 (sFRP4), reactive oxygen species modulator 1 (Romo1) and nuclear factor kappa B (NF-κB) as diagnostic and prognostic markers of endometrial cancer (EC) and ovarian cancer (OC). Methods: Thirty-one patients with EC and 30 patients with OC undergone surgical treatment were enrolled together with 30 healthy controls in a prospective study. Commercial ELISA kits determined serum TFF-3, Romo-1, NF-кB and sFRP-4 concentrations. Results: Serum TFF-3, Romo-1 and NF-кB levels were significantly higher in patients with EC and OC than those without cancer. Regarding EC, none of the serum biomarkers differs significantly between endometrial and non-endometrioid endometrial carcinomas. Mean serum TFF-3 and NF-кB levels were significantly higher in advanced stages. Increased serum levels of TFF-3 and NF-кB were found in those with a higher grade of the disease. Regarding OC, none of the serum biomarkers differed significantly among histological subtypes. Significantly increased serum levels of NF-кB were observed in patients with advanced-stage OC than those with stage I and II diseases. No difference in serum biomarker levels was found between those who had a recurrence and those who had not. The sensibility and specificity of these four biomarkers in discriminating EC and OC from the control group showed encouraging values, although no one reached 70%. Conclusions: TFF-3, Romo-1, NF-кB and SFRP4 could represent new diagnostic and prognostic markers for OC and EC. Further studies are needed to validate our results
A comprehensive analysis of the epidemiology and clinical characteristics of anti-LRP4 in myasthenia gravis
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Detection of collagen triple helix repeat containing-1 and nuclear factor (erythroid-derived 2)-like 3 in colorectal cancer
<p>Abstract</p> <p>Background</p> <p>Collagen Triple Helix Repeat Containing-1 (CTHRC1) and Nuclear factor (erythroid-derived 2)-like 3 (NFE2L3) may be useful biomarker candidates for the diagnosis of colorectal cancer (CRC) since they have shown an increase messenger RNA transcripts (mRNA) expression level in adenomas and colorectal tumours when compared to normal tissues.</p> <p>Methods</p> <p>To evaluate CTHRC1 and NFE2L3 as cancer biomarkers, it was generated and characterised several novel specific polyclonal antibodies (PAb), monoclonal antibodies (MAbs) and soluble Fab fragments (sFabs) against recombinant CTHRC1 and NFE2L3 proteins, which were obtained from different sources, including a human antibody library and immunised animals. The antibodies and Fab fragments were tested for recognition of native CTHRC1 and NFE2L3 proteins by immunoblotting analysis and enzyme-linked immunosorbent assay (ELISA) in colorectal cell lines derived from tumour and cancer tissues.</p> <p>Results</p> <p>Both, antibodies and a Fab fragment showed high specificity since they recognised only their corresponding recombinant antigens, but not a panel of different unrelated- and related proteins.</p> <p>In Western blot analysis of CTHRC1, a monoclonal antibody designated CH21D7 was able to detect a band of the apparent molecular weight of a full-length CTHRC1 in the human colon adenocarcinoma cell line HT29. This result was confirmed by a double antibody sandwich enzyme-linked immunosorbent assay (DAS-ELISA) with the monoclonal antibodies CH21D7 and CH24G2, detecting CTHRC1 in HT29 and in the colon adenocarcinoma cell line SW620.</p> <p>Similar experiments were performed with PAb, MAbs, and sFab against NFE2L3. The immunoblot analysis showed that the monoclonal antibody 41HF8 recognised NFE2L3 in HT29, and leukocytes. These results were verified by DAS-ELISA assay using the pairs PAb/sFab E5 and MAb 41HF8/sFab E5.</p> <p>Furthermore, an immunoassay for simultaneous detection of the two cancer biomarkers was developed using a Dissociation-Enhanced Lanthanide Fluorescent Immunoassay technology (DELFIA).</p> <p>Conclusions</p> <p>In conclusion, the antibodies obtained in this study are specific for CTHRC1 and NFE2L3 since they do not cross-react with unrelated- and related proteins and are useful for specific measurement of native CTHRC1 and NFE2L3 proteins. The antibodies and immunoassays may be useful for the analysis of CTHRC1 and NFE2L3 in clinical samples and for screening of therapeutic compounds in CRC.</p
The Klein-Gordon equation with the Kratzer potential in d dimensions
We apply the Asymptotic Iteration Method to obtain the bound-state energy
spectrum for the d-dimensional Klein-Gordon equation with scalar S(r) and
vector potentials V(r). When S(r) and V(r) are both Coulombic, we obtain all
the exact solutions; when the potentials are both of Kratzer type, we obtain
all the exact solutions for S(r)=V(r); if S(r) > V(r) we obtain exact solutions
under certain constraints on the potential parameters: in this case, a possible
general solution is found in terms of a monic polynomial, whose coefficients
form a set of elementary symmetric polynomials.Comment: 13 page
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