The Domestic Architecture of Collins and Harman in Canterbury, 1883 – 1927

This thesis explores the domestic designs produced in Canterbury, New Zealand, by the architectural firm of Collins and Harman between 1883 and 1927. Architects John James Collins (1855 – 1933) and Richard Dacre Harman (1859 – 1927) were partners in the firm founded in Christchurch by William Barnett Armson (1833 – 1883) in 1870. Like many New Zealand architects practicing at the turn of twentieth century, Collins and Harman worked amidst a climate of major social and economic transformation, yet they managed to navigate these transitions with their personal connections and respected positions within the local architectural profession. From Collins and Harman’s surviving architectural drawings and office records, the firm’s ability to design residences in accordance with its clients’ wishes is evaluated. The methods with which they carried out designs, transacted business and secured future clients are also considered. The social standing of the firm’s clientele is emphasised to highlight the tight-knit nature of architectural patronage in Canterbury during this period. In order to assess the firm’s contribution to the development of domestic architecture in New Zealand, the local architectural profession, the firm’s reputation, and the effects that its built designs had on its clients and the local community are also investigated. While their major public and commercial designs are included in general surveys of New Zealand architecture, Collins and Harman tend to be overlooked as domestic architects in comparison with better-known contemporaries such as Samuel Hurst Seager and Cecil Wood. In catering to the requirements of a diverse clientele, the firm adopted varied approaches in its designs, which illustrate a more complex evolution than the linear progression usually found in standard architectural historical methodologies. Divided chronologically into four distinct periods, the thesis focuses on key commissions to chart the firm’s development over forty-four years within the context of the evolution of domestic architecture in Canterbury. The diversity in its domestic work engendered by the firm’s professionalism demonstrates that Collins and Harman made a substantial and vital contribution in the development of domestic architecture in Canterbury

Leveraging the Creative Arts in Business Ethics Teaching

The purpose of this paper is to describe a way of teaching business ethics using the creative arts, especially literature and theater. By drawing on these disciplines for both method and texts, we can more easily make the connection to business as a fully human activity, concerned with how meaning is created. Students are encouraged to understand story-telling and narrative and how these tools lend insight into the daily life of businesspeople. The paper describes two main courses, Business Ethics Through Literature and Leadership, Ethics and Theater, and the rationale for each. We begin by suggesting three main leverage points that the courses engender. We then rely on the words of students who have taken the courses for insights into what they learned. We then critically assess some of the principles that have informed course design over time. We conclude by suggesting that paying attention to the creative arts gives rise to a rather different approach to business ethics, one grounded in the pragmatist tradition in philosophy

Longitudinal study of Asian elephants, Elephas maximus, indicates intermittent shedding of elephant endotheliotropic herpesvirus 1 during pregnancy

Introduction: EEHV-1 is a viral infection of elephants that has been associated with a fatal haemorrhagic syndrome in Asian elephants. Previous studies have suggested that pregnant animals may shed more virus than non-pregnant animals. Methods: This study examined whether pregnancy affected the frequency or magnitude of shedding of elephant endotheliotropic herpesvirus 1 (EEHV1) using Taq man real-time PCR on trunk washes from four female elephants from a UK collection over three time periods between 2011 and 2014. These periods included pregnancies in two animals (period 1 and period 3). Behavioural observations made by keepers were also assessed. Results: During period 1 there was a high degree of social hierarchical instability which led to a hierarchy change, and was associated with aggressive behaviour. Also during period 1 EEHV-1 shedding was of a higher magnitude and frequency than in the latter two time periods. Conclusions: These results suggest that there is no clear relationship between shedding and pregnancy, and that behavioural stressors may be related to an increase in EEHV-1 shedding

The VLA/ALMA Nascent Disk and Multiplicity (VANDAM) Survey of Perseus Protostars. VI. Characterizing the Formation Mechanism for Close Multiple Systems

We present Atacama Large Millimeter/submillimeter Array (ALMA) observations of multiple protostar systems in the Perseus molecular cloud previously detected by the Karl G. Jansky Very Large Array (VLA). We observed 17 close ($<$600~AU separation) multiple systems at 1.3~mm in continuum and five molecular lines (i.e., \twco, \cateo, \thco, H$_2$CO, SO) to characterize the circum-multiple environments in which these systems are forming. We detect at least one component in the continuum for the 17 multiple systems. In three systems, one companion is not detected, and for two systems the companions are unresolved at our observed resolution. We also detect circum-multiple dust emission toward 8 out of 9 Class 0 multiples. Circum-multiple dust emission is not detected toward any of the 8 Class I multiples. Twelve systems are detected in the dense gas tracers toward their disks/inner envelopes. For these 12 systems, we use the dense gas observations to characterize their formation mechanism. The velocity gradients in the circum-multiple gas are clearly orthogonal to the outflow directions in 8 out of the 12 systems, consistent with disk fragmentation. Moreover, only two systems with separations $<$200~AU are \textit{inconsistent} with disk fragmentation, in addition to the two widest systems ($>$500~AU). Our results suggest that disk fragmentation via gravitational instability is an important formation mechanism for close multiple systems, but further statistics are needed to better determine the relative fraction formed via this method.Comment: 48 Pages, 26 Figures, 7 Tables, Accepted by Ap

Evaluating the association of TRPA1 gene polymorphisms with pain sensitivity:a protocol for an adaptive recall by genotype study

BACKGROUND: Pain is a complex polygenic trait whose common genetic underpinnings are relatively ill-defined due in part to challenges in measuring pain as a phenotype. Pain sensitivity can be quantified, but this is difficult to perform at the scale required for genome wide association studies (GWAS). Existing GWAS of pain have identified surprisingly few loci involved in nociceptor function which contrasts strongly with rare monogenic pain states. This suggests a lack of resolution with current techniques. We propose an adaptive methodology within a recall-by-genotype (RbG) framework using detailed phenotyping to screen minor alleles in a candidate ‘nociceptor’ gene in an attempt to estimate their genetic contribution to pain. METHODS/DESIGN: Participants of the Avon Longitudinal Study of Parents and Children will be recalled on the basis of genotype at five common non-synonomous SNPs in the ‘nociceptor’ gene transient receptor potential ankylin 1 (TRPA1). Those homozygous for the common alleles at each of the five SNPs will represent a control group. Individuals homozygous for the minor alleles will then be recruited in a series of three sequential test groups. The outcome of a pre-planned early assessment (interim) of the current test group will determine whether to continue recruitment or switch to the next test group. Pain sensitivity will be assessed using quantitative sensory testing (QST) before and after topical application of 10% cinnamaldehyde (a TRPA1 agonist). DISCUSSION: The design of this adaptive RbG study offers efficiency in the assessment of associations between genetic variation at TRPA1 and detailed pain phenotypes. The possibility to change the test group in response to preliminary data increases the likelihood to observe smaller effect sizes relative to a conventional multi-armed design, as well as reducing futile testing of participants where an effect is unlikely to be observed. This specific adaptive RbG design aims to uncover the influence of common TRPA1 variants on pain sensation but can be applied to any hypothesis-led genotype study where costly and time intensive investigation is required and / or where there is large uncertainty around the expected effect size. Trial registration: ISRCTN, ISRCTN16294731. Retrospectively registered 25th November 2021. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12920-022-01156-5

Exploring women’s experiences of breast or trunk lymphoedema following treatment for breast cancer

Background: The experiences of women who develop lymphoedema in the breast or trunk (BTL) after treatment for breast cancer have received little attention in either the academic or clinical setting. Consequently, women’s support needs remain unrecognized. Objective and Design: As this study sought to gain an understanding of women’s unheard experiences of a poorly understood condition, it was underpinned by The Silences FrameworkCitation1 which facilitates research into sensitive or marginalized issues. Sample and Methods: Fourteen women with BTL participated in individual, unstructured interviews, some using photographs or drawings to reflect their experiences. The data was analyzed using the Listening Guide.Citation2 Findings: Participants revealed that they were unprepared for the development of BTL; for many, the symptoms were unfamiliar and distressing. Furthermore, their concerns were often dismissed by healthcare professionals (HCPs), leading to long delays in obtaining an accurate diagnosis and treatment. For some women, the practical and emotional impact of developing BTL was profound. Practice Implications: Increased awareness and education about the risk of BTL as a potential side-effect of treatment for breast cancer is required for HCPs and patients. This will alleviate distress, better prepare patients, and ensure timely referral for treatment to manage this chronic condition

Exploring women’s experiences of breast or trunk lymphoedema following treatment for breast cancer

Background:The experiences of women who develop lymphoedema in the breast or trunk (BTL) after treatment for breast cancer have received little attention in either the academic or clinical setting. Consequently, women’s support needs remain unrecognized.Objective and Design:As this study sought to gain an understanding of women’s unheard experiences of a poorly understood condition, it was underpinned by The Silences Framework which facilitates research into sensitive or marginalized issues.Sample and Methods:Fourteen women with BTL participated in individual, unstructured interviews, some using photographs or drawings to reflect their experiences. The data was analyzed using the Listening Guide.Findings:Participants revealed that they were unprepared for the development of BTL; for many, the symptoms were unfamiliar and distressing. Furthermore, their concerns were often dismissed by healthcare professionals (HCPs), leading to long delays in obtaining an accurate diagnosis and treatment. For some women, the practical and emotional impact of developing BTL was profound.Practice Implications:Increased awareness and education about the risk of BTL as a potential side-effect of treatment for breast cancer is required for HCPs and patients. This will alleviate distress, better prepare patients, and ensure timely referral for treatment to manage this chronic condition

High Resolution 8 mm and 1 cm Polarization of IRAS 4A from the VLA Nascent Disk and Multiplicity (VANDAM) Survey

Magnetic fields can regulate disk formation, accretion and jet launching. Until recently, it has been difficult to obtain high resolution observations of the magnetic fields of the youngest protostars in the critical region near the protostar. The VANDAM survey is observing all known protostars in the Perseus Molecular Cloud. Here we present the polarization data of IRAS 4A. We find that with ~ 0.2'' (50 AU) resolution at {\lambda} = 8.1 and 10.3 mm, the inferred magnetic field is consistent with a circular morphology, in marked contrast with the hourglass morphology seen on larger scales. This morphology is consistent with frozen-in field lines that were dragged in by rotating material entering the infall region. The field morphology is reminiscent of rotating circumstellar material near the protostar. This is the first polarization detection of a protostar at these wavelengths. We conclude from our observations that the dust emission is optically thin with {\beta} ~ 1.3, suggesting that mm/cm-sized grains have grown and survived in the short lifetime of the protostar.Comment: Accepted to ApJL. 13 pages, 4 figure

Sustainability at Banorte: A Comprehensive CSR Strategy

As financial institutions approach sustainability in new ways, this report, prepared as a master's project for the School of Natural Resources and Environment, represents an innovative comprehensive corporate social responsibility strategy for the 3rd largest bank in Mexico, Grupo Financiero Banorte (Banorte). Through an extensive review of CSR literature, a compilation of best practices, and incorporation of organizational and decision-making frameworks most relevant to CSR, the report provides an overview of the year-long collaboration between Banorte and University of Michigan students from the Erb Institute for Global Sustainable Enterprise. This collaboration yielded key current and future short and long-term steps that will allow the bank to better integrate CSR (environmental, social and financial performance) into its core business strategy. In addition, the report includes two representative case studies of CSR initiatives: Small and Medium Enterprise education and Paper Reduction. Each of these studies provides key learnings and insights applicable for continued progress in creating an innovative corporate social responsibility strategy over the next three years and beyond.Master of ScienceNatural Resources and EnvironmentUniversity of Michiganhttp://deepblue.lib.umich.edu/bitstream/2027.42/83665/1/Banorte Revised SNRE V5 MM.pd