CONVERSION OF A LAMB PRODUCTION SYSTEM TO ORGANIC FARMING: HOW TO MANAGE, FOR WHICH RESULTS?

Two sheep flocks were managed organically (for two years from conversion onwards) under different lambing strategies (1 lambing/year vs. 3 lambings every two years). The second system was tested as there was a producer’s interest in high productivity that is a guarantee of good economic results in conventional. Reproduction, feeding, lamb production, carcass quality, health (particularly internal parasitism), economic return of the flock, grass production, and pasture biodiversity were evaluated. The lambs were bred under low therapeutic input. The economical advantage of increasing lambing frequency was not demonstrated, whereas this strategy complexified management and resulted in higher internal parasitic infection of the lambs, and finally showed a lower stability. There were difficulties in establishing a very high feed self-sufficiency in both systems, especially the more intensive system (4 points lower), due to harsh climatic conditions; following this five-year experiment, we are changing our strategy to provide nitrogen in the systems

CONVERSION OF A LAMB PRODUCTION SYSTEM TO ORGANIC FARMING: HOW TO MANAGE, FOR WHAT RESULTS?

Two sheep flocks were managed organically for two years from conversion under different lambing strategies (1 lambing/year vs. 3 lambings every two years). The second system was tested because pf a producer’s interest in high productivity, which is a guarantee of good economic results in conventional production.. Reproduction, feeding, lamb production, carcass quality, health (particularly internal parasitism), economic return of the flock, grass production, and pasture biodiversity were evaluated. The lambs were bred with low therapeutic inputs. No economic advantage of increasing lambing frequency was demonstrated, whereas this strategy complicated management and resulted in higher internal parasitic infection of the lambs, and finally showed lower stability. There were difficulties in establishing a very high feed self-sufficiency in both systems, especially the more intensive system (4 points lower), due to harsh climatic conditions. Following this five-year experiment, we are changing our strategy to provide nitrogen in the systems

Dietary experience modifies horses' feeding behavior and selection patterns of three macronutrient rich diets

Choice feeding is often used to investigate an animal’s nutritional requirements and dietary preferences. A problem with this approach is that animals with long gut transit times, such as the horse, may find it difficult to associate a chosen food with its nutritional consequence when alternative foods are presented simultaneously. One solution is to present foods singly for a period of time before a simultaneous choice session to allow the development of learned associations. This method was used to determine if horse’s voluntary intake and feeding behavior was influenced by the macronutrient composition of the diet. Seven stabled horses, maintained on a low intensity exercise regimen, were allowed, on an ad libitum basis, haylage and 3 isocaloric forage based diets that were rich in 1 of 3 macronutrients (protein, lipid, and hydrolyzable carbohydrate). Initially, diets were presented as a 3-way choice for 5 d (self-selection a [SSa]), then singly (monadic phase) with exposure to each diet for 2 separate periods of 3 d each, and finally again as a choice for 5 d (self-selection b [SSb]). The total amount of trial diet offered differed with trial phase, with 2 to 2.5% of BW during SSa and the monadic phase, increasing to ad libitum access during SSb. To control differences in the total amount of trial diet offered, 2 measurements of voluntary intake were taken at 4 and 22 h postpresentation. Daily macronutrient and energy intakes were estimated from proximate analysis of the trial diets and batches of haylage fed. Feeding behavior was observed over a single 4-h period during both self-selection phases. Horses showed no initial preference after 4 h for any 1 diet during SSa. Following the monadic phase, horses demonstrated a preference for the protein and hydrolyzable carbohydrate rich diets over the lipid rich diet (P < 0.001). Dietary experience modified foraging behavior as the total number of visits to the diets decreased during SSb (P < 0.005). Analysis of 24 -h macronutrient consumption showed that protein and hydrolyzable carbohydrate intake increased during SSb, whereas lipid intake remained constant over both self-selection phases (P < 0.001). These data indicate for perhaps the first time that horses can respond to dietary macronutrient content and that single presentations during choice studies facilitates expression of dietary preferences

La guerre d’Algérie dans les relations Franco-espagnoles

Comparer le retentissement de la guerre d’Algérie dans les relations de la France avec l’Espagne et l’Italie conduit à dégager une chronologie particulière dans le cas espagnol. Après avoir fait preuve d’une hostilité qui le distinguait des pays occidentaux, sur fond de rivalité des politiques arabes et de crise marocaine, le régime franquiste se rapproche de la position française en 1957, alors même que la pression internationale s’accroît ; il apporte toutefois un soutien conditionnel, d’où un constant marchandage qui lève le contentieux pendant. Paradoxalement, la guerre d’Algérie scelle ainsi la réconciliation bilatérale.A comparative study of the impact of the Algerian war on the relations of France with Spain and Italy brings a special chronology in the Spanish case to light. First, with the rivalry between Arab politics and the Moroccan crisis behind, the franquist power shows an hostility that distinguishes it from the Occidental countries. Then the regime comes close to French position in 1957, while the international pressure grows ; its support is conditional howewer, and always accompanied by bargaining which removes the pending disputes. Paradoxically, the Algerian war leads to a bilateral reconciliation

Potentially toxic metals in historic landfill sites: Implications for grazing animals

Municipal waste disposal is an increasing global problem, frequently solved by the use of landfill sites. Following closure, such sites contain a legacy of pollutants and must be managed to provide a safe and useful end life. The soils and vegetation from four historic landfill sites were analysed to determine the extent of pollution by potentially toxic metals (PTMs). Data were subsequently assessed to determine if post closure uses involving grazing were safe for the animals. The heaviest and widest spread soil contamination was due to Ni. Concentrations at all sites exceeded the 95th percentile value for rural soils, in one case by a factor of 30. Cu and Pb contamination was identified at some sites, but no evidence of Al or Zn contamination was found. Oral bioaccessibility testing showed that the availability of Ni in soil was exceedingly low, whilst that of Cu and Pb was high. Concentrations in plant shoots differed significantly amongst the sites, but interspecific differences in shoot concentration were only significant in the case of Cu. The results indicated that exposure levels to grazers would be at or below tolerable levels, indicating that it is generally safe to graze historic landfill. However, animals could be exposed to higher levels of PTMs than would be expected from rural locations, and grazing under conditions where soil consumption may be high could result in levels of exposure to Al, Ni and Pb exceeding tolerable levels. © Springer International Publishing 2014

Methane emission by Camelids

Methane emissions from ruminant livestock have been intensively studied in order to reduce contribution to the greenhouse effect. Ruminants were found to produce more enteric methane than other mammalian herbivores. As camelids share some features of their digestive anatomy and physiology with ruminants, it has been proposed that they produce similar amounts of methane per unit of body mass. This is of special relevance for countrywide greenhouse gas budgets of countries that harbor large populations of camelids like Australia. However, hardly any quantitative methane emission measurements have been performed in camelids. In order to fill this gap, we carried out respiration chamber measurements with three camelid species (Vicugna pacos, Lama glama, Camelus bactrianus; n = 16 in total), all kept on a diet consisting of food produced from alfalfa only. The camelids produced less methane expressed on the basis of body mass (0.3260.11 L kg21 d21) when compared to literature data on domestic ruminants fed on roughage diets (0.5860.16 L kg21 d21). However, there was no significant difference between the two suborders when methane emission was expressed on the basis of digestible neutral detergent fiber intake (92.7633.9 L kg21 in camelids vs. 86.2612.1 L kg21 in ruminants). This implies that the pathways of methanogenesis forming part of the microbial digestion of fiber in the foregut are similar between the groups, and that the lower methane emission of camelids can be explained by their generally lower relative food intake. Our results suggest that the methane emission of Australia’s feral camels corresponds only to 1 to 2% of the methane amount produced by the countries’ domestic ruminants and that calculations of greenhouse gas budgets of countries with large camelid populations based on equations developed for ruminants are generally overestimating the actual levels

NKG2D/NKG2-Ligand Pathway Offers New Opportunities in Cancer Treatment

The antitumor functions of NK cells are regulated by the integration of positive and negative signals triggered by numerous membrane receptors present on the NK cells themselves. Among the main activating receptors, NKG2D binds several stress-induced molecules on tumor targets. Engagement of NKG2D by its ligands (NKG2D-Ls) induces NK cell activation leading to production of cytokines and target cell lysis. These effects have therapeutic potential as NKG2D-Ls are widely expressed by solid tumors, whereas their expression in healthy cells is limited. Here, we describe the genetic and environmental factors regulating the NKG2D/NKG2D-L pathway in tumors. NKG2D-L expression is linked to cellular stress and cell proliferation, and has been associated with oncogenic mutations. Tumors have been found to alter their to NKG2D-L expression as they progress, which interferes with the antitumor function of the pathway. Nevertheless, this pathway could be advantageously exploited for cancer therapy. Various cancer treatments, including chemotherapy and targeted therapies, indirectly interfere with the cellular and soluble forms of NKG2D-Ls. In addition, NKG2D introduced into chimeric antigen receptors in T- and NK cells is a promising tumor immunotherapy approach

Estimation of the duodenal flow of microbial nitrogen in ruminants based on the chemical composition of forages: a literature review

The objective of this study was to evaluate the estimation of the duodenal flow of microbial nitrogen (N) in ruminants fed forage only, per kilogram of dry matter (DM) intake, which is the yield of microbial protein (YMP). The estimation was based on the chemical composition of forages. A data file of 62 observations was collected from in vivo studies on cattle and sheep fed diets with forage only. A statistical analysis of YMP was conducted with neutral detergent fibre (NDF), crude protein (CP), non structural carbohydrates (NSC), group of forage species (legumes or grasses), method of conservation, physical form of presentation, level of DM intake, animal species, methodology and references as parameters. After a stepwise regression, CP was significant and the most important predictor. NSC or the method of conservation had an extra effect on YMP. On the basis of these three parameters the best fit equations were found and the influence of all parameters on YMP were discussed. Using the data file of this study, the prediction of YMP from the PDI-system was also validated. The statistics of the validation of the PDI prediction were similar to the statistics of the equations from this study. In conclusion, the chemical composition of forages, with or without the method of conservation, is a poor indication for the duodenal flow of microbial N (g $\cdot$kg -1 DM intake) in ruminants fed diets with forages only