Additional Evidence Supporting a Model of Shallow, High-Speed Supergranulation

Recently, Duvall and Hanasoge ({\it Solar Phys.} {\bf 287}, 71-83, 2013) found that large distance $[\Delta]$ separation travel-time differences from a center to an annulus $[\delta t_{\rm{oi}}]$ implied a model of the average supergranular cell that has a peak upflow of $240\rm{ms^{-1}}$ at a depth of $2.3\rm{Mm}$ and a corresponding peak outward horizontal flow of $700\rm{ms^{-1}}$ at a depth of $1.6\rm{Mm}$. In the present work, this effect is further studied by measuring and modeling center-to-quadrant travel-time differences $[\delta t_{\rm{qu}}]$, which roughly agree with this model. Simulations are analyzed that show that such a model flow would lead to the expected travel-time differences. As a check for possible systematic errors, the center-to-annulus travel-time differences $[\delta t_{\rm{oi}}]$ are found not to vary with heliocentric angle. A consistency check finds an increase of $\delta t_{\rm{oi}}$ with the temporal frequency $[\nu]$ by a factor of two, which is not predicted by the ray theory

Validated helioseismic inversions for 3-D vector flows

According to time-distance helioseismology, information about internal fluid motions is encoded in the travel times of solar waves. The inverse problem consists of inferring 3-D vector flows from a set of travel-time measurements. Here we investigate the potential of time-distance helioseismology to infer 3-D convective velocities in the near-surface layers of the Sun. We developed a new Subtractive Optimally Localised Averaging (SOLA) code suitable for pipeline pseudo-automatic processing. Compared to its predecessor, the code was improved by accounting for additional constraints in order to get the right answer within a given noise level. The main aim of this study is to validate results obtained by our inversion code. We simulate travel-time maps using a snapshot from a numerical simulation of solar convective flows, realistic Born travel-time sensitivity kernels, and a realistic model of travel-time noise. These synthetic travel times are inverted for flows and the results compared with the known input flow field. Additional constraints are implemented in the inversion: cross-talk minimization between flow components and spatial localization of inversion coefficients. Using modes f, p1 through p4, we show that horizontal convective flow velocities can be inferred without bias, at a signal-to-noise ratio greater than one in the top 3.5 Mm, provided that observations span at least four days. The vertical component of velocity (v_z), if it were to be weak, is more difficult to infer and is seriously affected by cross-talk from horizontal velocity components. We emphasise that this cross-talk must be explicitly minimised in order to retrieve v_z in the top 1 Mm. We also show that statistical averaging over many different areas of the Sun allows for reliably measuring of average properties of all three flow components in the top 5.5 Mm of the convection zone.Comment: 14 pages main paper, 9 pages electronic supplement, 28 figures. Accepted for publication in Astronomy & Astrophysic

Seismic Constraints on Interior Solar Convection

We constrain the velocity spectral distribution of global-scale solar convective cells at depth using techniques of local helioseismology. We calibrate the sensitivity of helioseismic waves to large-scale convective cells in the interior by analyzing simulations of waves propagating through a velocity snapshot of global solar convection via methods of time-distance helioseismology. Applying identical analysis techniques to observations of the Sun, we are able to bound from above the magnitudes of solar convective cells as a function of spatial convective scale. We find that convection at a depth of $r/R_\odot = 0.95$ with spatial extent $\ell <20$, where $\ell$ is the spherical harmonic degree, comprise weak flow systems, on the order of 15 m/s or less. Convective features deeper than $r/R_\odot = 0.95$ are more difficult to image due to the rapidly decreasing sensitivity of helioseismic waves.Comment: accepted, ApJ Letters, 5 figures, 10 pages (in this version

Probing sunspots with two-skip time-distance helioseismology

Previous helioseismology of sunspots has been sensitive to both the structural and magnetic aspects of sunspot structure. We aim to develop a technique that is insensitive to the magnetic component so the two aspects can be more readily separated. We study waves reflected almost vertically from the underside of a sunspot. Time-distance helioseismology was used to measure travel times for the waves. Ray theory and a detailed sunspot model were used to calculate travel times for comparison. It is shown that these large distance waves are insensitive to the magnetic field in the sunspot. The largest travel time differences for any solar phenomena are observed. With sufficient modeling effort, these should lead to better understanding of sunspot structure

Comparison of H alpha synoptic charts with the large-scale solar magnetic field as observed at Stanford

Two methods of observing the neutral line of the large-scale photospheric magnetic field are compared: (1) neutral line positions inferred from H alpha photographs and (2) observations of the photospheric magnetic field made with low spatial resolution (3 arc min.) and high sensitivity using the Stanford magnetograph. The comparison is found to be very favorable

Solar meridional circulation from twenty-one years of SOHO/MDI and SDO/HMI observations: Helioseismic travel times and forward modeling in the ray approximation

The south-north travel-time differences are measured by applying time-distance helioseismology to the MDI and HMI medium-degree Dopplergrams covering May 1996-April 2017. Our data analysis corrects for several sources of systematic effects: P-angle error, surface magnetic field effects, and center-to-limb variations. An interpretation of the travel-time measurements is obtained using a forward-modeling approach in the ray approximation. The travel-time differences are similar in the southern hemisphere for cycles 23 and 24. However, they differ in the northern hemisphere between cycles 23 and 24. Except for cycle 24's northern hemisphere, the measurements favor a single-cell meridional circulation model where the poleward flows persist down to $\sim$0.8 $R_\odot$, accompanied by local inflows toward the activity belts in the near-surface layers. Cycle 24's northern hemisphere is anomalous: travel-time differences are significantly smaller when travel distances are greater than 20$^\circ$. This asymmetry between northern and southern hemispheres during cycle 24 was not present in previous measurements (e.g., Rajaguru & Antia 2015), which assumed a different P-angle error correction where south-north travel-time differences are shifted to zero at the equator for all travel distances. In our measurements, the travel-time differences at the equator are zero for travel distances less than $\sim$30$^\circ$, but they do not vanish for larger travel distances. This equatorial offset for large travel distances need not be interpreted as a deep cross-equator flow; it could be due to the presence of asymmetrical local flows at the surface near the end points of the acoustic ray paths.Comment: accepted for publication in A&

Poly(2-propylacrylic acid)/poly(lactic-co-glycolic acid) blend microparticles as a targeted antigen delivery system to direct either CD4+ or CD8+ T cell activation.

Poly(lactic-co-glycolic acid) (PLGA) based microparticles (MPs) are widely investigated for their ability to load a range of molecules with high efficiency, including antigenic proteins, and release them in a controlled manner. Micron-sized PLGA MPs are readily phagocytosed by antigen presenting cells, and localized to endosomes. Due to low pH and digestive enzymes, encapsulated protein cargo is largely degraded and processed in endosomes for MHC-II loading and presentation to CD4+ T cells, with very little antigen delivered into the cytosol, limiting MHC-I antigenic loading and presentation to CD8+ T cells. In this work, PLGA was blended with poly(2-propylacrylic acid) (PPAA), a membrane destabilizing polymer, in order to incorporate an endosomal escape strategy into PLGA MPs as an easily fabricated platform with diverse loading capabilities, as a means to enable antigen presentation to CD8+ T cells. Ovalbumin (OVA)-loaded MPs were fabricated using a water-in-oil double emulsion with a 0% (PLGA only), 3 and 10% PPAA composition. MPs were subsequently determined to have an average diameter of 1 µm, with high loading and a release profile characteristic of PLGA. Bone marrow derived dendritic cells (DCs) were then incubated with MPs in order to evaluate localization, processing, and presentation of ovalbumin. Endosomal escape of OVA was observed only in DC groups treated with PPAA/PLGA blends, which promoted high levels of activation of CD8+ OVA-specific OT-I T cells, compared to DCs treated with OVA-loaded PLGA MPs which were unable activate CD8+ T cells. In contrast, DCs treated with OVA-loaded PLGA MPs promoted OVA-specific OT-II CD4+ T cell activation, whereas PPAA incorporation into the MP blend did not permit CD4+ T cell activation. These studies demonstrate PLGA MP blends containing PPAA are able to provide an endosomal escape strategy for encapsulated protein antigen, enabling the targeted delivery of antigen for tunable presentation and activation of either CD4+ or CD8+ T cells

Global-scale equatorial Rossby waves as an essential component of solar internal dynamics

The Sun's complex dynamics is controlled by buoyancy and rotation in the convection zone and by magnetic forces in the atmosphere and corona. While small-scale solar convection is well understood, the dynamics of large-scale flows in the solar convection zone is not explained by theory or simulations. Waves of vorticity due to the Coriolis force, known as Rossby waves, are expected to remove energy out of convection at the largest scales. Here we unambiguously detect and characterize retrograde-propagating vorticity waves in the shallow subsurface layers of the Sun at angular wavenumbers below fifteen, with the dispersion relation of textbook sectoral Rossby waves. The waves have lifetimes of several months, well-defined mode frequencies below 200 nHz in a co-rotating frame, and eigenfunctions of vorticity that peak at the equator. Rossby waves have nearly as much vorticity as the convection at the same scales, thus they are an essential component of solar dynamics. We find a transition from turbulence-like to wave-like dynamics around the Rhines scale of angular wavenumber of twenty; this might provide an explanation for the puzzling deficit of kinetic energy at the largest spatial scales.Comment: This is the submitted version of the paper published in Nature Astronomy. 23 pages, 8 figures, 1 tabl

Time-distance analysis of the emerging active region NOAA 10790

We investigate the emergence of Active Region NOAA 10790 by means of time – distance helioseismology. Shallow regions of increased sound speed at the location of increased magnetic activity are observed, with regions becoming deeper at the locations of sunspot pores. We also see a long-lasting region of decreased sound speed located underneath the region of the flux emergence, possibly relating to a temperature perturbation due to magnetic quenching of eddy diffusivity, or to a dense flux tube. We detect and track an object in the subsurface layers of the Sun characterised by increased sound speed which could be related to emerging magnetic-flux and thus obtain a provisional estimate of the speed of emergence of around 1 km s−1