Reg en etiek – Enkele implikasies

Sodra enige wetenskaplike die etiek as sodanig, of die regswetenskaplike die etiek in sy samehang met die regswetenskap wil gaan besien, kan hy seker wees dat hy vir homself ’n turksvy gepluk het. Dit ontneem horn egter nie sy wetenskaplike verantwoordelikheid om hierdie turksvy te probeer afskil nie

Enkele opmerkings oor wet en orde en konflik

Law and order are indivisibly linked in the minds of men. The issue that is examined in this paper is whether the nature of law and order in a society is such that it can co-exist with (social) conflict. The issue is approached with the theoretical vision aimed at, firstly, order, and subsequently, the Linked concepts of "law/justice and order". A brief perspective is provided of the Western concept of order. The author dissociated himself from a concept of order which conceives of Itself as intrinsically being an abstract, idealized image of peace and harmony, which pretends to embody (something of) an order of creation (or of rational insight by men) in normative terms, which seeks to be Imposed on human societies

Forensic entomology: relevant to legal dispute resolution?

Forensic entomology is the study of insects and other arthropods associated with certain suspected criminal events, for the purpose of uncovering information useful to a legal investigation. This contribution considers the relevance of this biological science to the judicial process.We conclude that although the inherent nature of the science and a lack of expertise and resources hamper its integration into the legal system, its value and general acceptance is consistently recognized in other jurisdictions. Although forensic entomology evidence has to date been accepted in only one South African case, it has been utilized in numerous criminal investigations in this country. Also, various initiatives have been launched to increase its utilization and improve the reliability of its results. If these endeavours prove to be successful, forensic entomology could become increasingly relevant to legal dispute resolution

Aborsie: ’n Juridiese, etiese en regsetiese vraagstuk

In die geledere van skokkende en onetiese dade in die menslike samelewing, beklee aborsie ’n besondere plek. Vir wetenskaplike doeleindes kan aborsie oor die algemeen gedefinieer word as die skeiding van of afdrywing uit die moederlyf van die „produk” van konsepsie, synde ’n fetus (Geldenhuys, 1974:11; O’Donovan 1975:2). ’n Verdere element van die definisie, wat die blote afdrywing van die vrug gewoonlik kwalifiseer, is dat die fetus, met betrekking tot nageboortelike lewe gesproke, nie lewensvatbaar moes gewees het nie. Met die byvoeging van hierdie element tot die eie definisie word tans egter vertoef ten einde eers die belangrike vraag wanneer lewe ontstaan, te beantwoord

Evaluation of Selected Aspects of the Nutrition Therapeutic Programme Offered to HIV-Positive Women of Child-Bearing Age in Western Cape Province, South Africa

Background: The Nutrition Therapeutic Programme (NTP) involves the provision of food supplements at primary health clinics (PHCs) to correct nutritional deficiencies in vulnerable groups. Although previous studies have identified problems with implementing the programme at PHCs, assessments of its efficiency have been scarce.Objective: To evaluate implementation of the NTP at PHCs that provide antiretroviral therapy.Methods: A cross-sectional, descriptive study was conducted at 17 PHCs located within 3 districts of Western Cape Province. Two target groups were chosen: 32 staff members working at the sites and 21 women of child-bearing age enrolled in the NTP. Questionnaires were used to obtain data.Results: Only 2 women (10%) lived in food-secure households; the rest were either at risk of hunger (29%) or classified as hungry (61%). Most of the women knew they had to take the supplements to improve their nutritional status, but the majority only recalled receiving basic nutritional advice, and the information was mainly given verbally. Ten of the women had shared their supplements with others, mostly with their children. The study identified lack of clearly defined NTP responsibilities at the PHCs, causing confusion amongst the staff. Although many staff members expressed problems with the NTP, only 38% of them reported having routine evaluations regarding the programme.Conclusion: Several aspects compromised the effectiveness of the NTP, including socioeconomic factors leading to clients’ non-compliance. The strategic organisation and implementation of the NTP varied between different PHCs offering antiretroviral therapy, and staff experienced difficulties with the logistics of the programme

Access to chloroquine in patients with rheumatic and musculoskeletal diseases attending rheumatology outpatient clinics during the COVID-19 pandemic

Herbal medicines made from the bark of the Cinchona tree, and later quinine, have been widely used for centuries to treat medical conditions such as tropical malaria. More recently, chloroquine (CQ) and its synthetic derivatives have been used as antimalarials and to treat systemic lupus erythematosus, rheumatoid arthritis, and in the past 14 months or so, COVID-19 pneumonia. Anecdotal evidence and the erratic covering through social media of its potential efficacy in the treatment of COVID-19 pneumonia have resulted in the widespread off-label use of CQ in South Africa and worldwide. This study aimed to show that access to CQ as a chronic medication for rheumatic and musculoskeletal diseases was limited during the COVID-19 pandemic, and that this resulted in an increased incidence of flares in these patients, affecting their morbidity and potentially leading to mortality

Using research on self-regulation to understand and tackle the challenges that owners face helping their (overweight) dogs lose weight

The present research sought to (i) understand the challenges that dog owners encounter in helping their pet lose weight, and (ii) develop and test an intervention designed to help dog owners to deal with these challenges. A series of focus groups (N = 79 dog owners, veterinarians, and industry experts) informed the content of an intervention designed to prompt owners to form if-then plans (or “implementation intentions”) identifying challenges (e.g., inclement weather) and specifying how to respond (e.g., play with the dog indoors). This intervention was evaluated in a single-blind, randomized controlled trial (N = 106 owners of overweight dogs) against a control condition who were simply asked to set relevant goals. Changes in the owners’ beliefs, behaviour, and the dog’s weight and body condition were measured around 2 months later. The primary finding was that dogs in the intervention condition lost the same percentage of their body weight on average each week (M = -0.065, SD = 0.65) as dogs in the control condition (M = −0.24, SD = 0.55), F(1, 36) = 0.70, p =  .41, eta2 = .019, although it should be noted that follow-up data was only available for around half of the sample. Analysis of the factors that were associated with changes in weight among the dogs in the trial suggested that owners’ lack of knowledge about appropriate feeding and exercise was associated with poorer outcomes, suggesting that future interventions may need to provide information and help owners to set appropriate goals before encouraging them to make if-then plans to support the implementation of those goals

Cross pathogenicity of Neofusicoccum australe and Neofusicoccum stellenboschiana on grapevine and selected fruit and ornamental trees

[EN] Neofusicoccum australe is one of the most important Botryosphaeriaceae pathogens occurring on fruit and vine crops. This fungus was recently taxonomically reassessed, identifying N. stellenboschiana as a separate species. Previous pathogenicity studies used N. stellenboschiana and N. australe isolates as N. australe, so assessment of the pathogenicity of these two species on grapevine and other hosts was required. A pathogenicity trial was conducted on detached shoots of grapevine, plum, apple, olive and Peruvian pepper tree. Shoots were individually inoculated with 11 N. australe and eight N. stellenboschiana isolates originally isolated from grapevine, plum, apple, olive, Peruvian pepper and fig. Both species formed lesions on all five hosts and were reisolated 5 weeks post-inoculation. In general, the largest lesions were formed on plum and smallest on Peruvian pepper. Isolate host origin did not influence ability to cause lesions on other hosts. Isolates of N. australe and N. stellenboschiana differed in virulence on the various hosts, ranging from those that caused the largest lesions, a group causing intermediate lesions, and another causing lesions similar to uninoculated controls. The study demonstrates that N. australe and N. stellenboschiana isolates originating from various fruit hosts can infect alternative hosts including grapevine and other major fruit crops.This research developed from a mobility sojourn funded by the Erasmus Mundus Joint Master Degrees Programme of the European Commission under the PLANT HEALTH Project. The authors also acknowledge financial support from ARC Infruitec-Nietvoorbij and the National Research Foundation of South Africa (NRF UID88771). Technical Assistance was provided by Carine Vermeulen, Danie Marais, Julia Marais, Muriel Knipe, Lydia Maart, Christopher Paulse, Bongiwe Sokwaliwa, Nadeen van Kervel, and Levocia Williams (Plant Protection Division, ARC Infruitec-Nietvoorbij).Mojeremane, K.; Lebenya, P.; Du Plessis, IL.; Van Der Rijst, M.; Mostert, L.; Armengol Fortí, J.; Halleen, F. (2020). Cross pathogenicity of Neofusicoccum australe and Neofusicoccum stellenboschiana on grapevine and selected fruit and ornamental trees. PHYTOPATHOLOGIA MEDITERRANEA. 59(3):581-593. https://doi.org/10.14601/Phyto-11609S58159359

Factors moderating the relationship between childhood trauma and premorbid adjustment in first-episode schizophrenia

CITATION: Kilian, S. et al. 2017. Factors moderating the relationship between childhood trauma and premorbid adjustment in first-episode schizophrenia. PLoS ONE, 12(1):e0170178, doi:10.1371/journal.pone.0170178.The original publication is available at http://journals.plos.org/plosoneChildhood trauma is a recognised risk factor for schizophrenia. It has been proposed that childhood trauma interferes with normal neurodevelopment, thereby establishing a biological vulnerability to schizophrenia. Poor premorbid adjustment is frequently a precursor to schizophrenia, and may be a manifestation of neurodevelopmental compromise. We investigated the relationship between childhood trauma and premorbid adjustment in 77 patients with first-episode schizophrenia spectrum disorders. We also investigated possible mediating roles for other selected risk factors in the relationship. We found several significant correlations between different trauma types and both social and academic premorbid adjustment from childhood to late adolescence. There were no significant moderating effects for family history of schizophrenia or family history of psychiatric disorder. History of obstetric complications, substance abuse and poor motor coordination weakened some of the associations between childhood trauma and premorbid adjustment, while poor sequencing of motor acts strengthened the association. Our results confirm previous studies indicating an association between childhood trauma and premorbid adjustment. Results indicate a general rather than specific association, apparent with different types of trauma, and affecting both social and academic components of premorbid adjustment across childhood, early and late adolescence. Further, our results suggest a complex interplay of various risk factors, supporting the notion of different pathways to psychosis.http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0170178Publisher's versio

Density functional study of the actinide nitrides

The full potential all electron linearized augmented plane wave plus local orbitals (FP-LAPW + lo) method, as implemented in the suite of software WIEN2K, has been used to systematically investigate the structural, electronic, and magnetic properties of the actinide compounds AnN (An = Ac, Th, Pa, U, Np, Pu, Am). The theoretical formalism used is the generalized gradient approximation to density functional theory (GGA-DFT) with the Perdew-Burke-Ernzerhof (PBE) exchange-correlation functional. Each compound has been studied at six levels of theory: non-magnetic (NM), non-magnetic with spin-orbit coupling (NM+SOC), ferromagnetic (FM), ferromagnetic with spin-orbit coupling (FM+SOC), anti-ferromagnetic (AFM), and anti-ferromagnetic with spin-orbit coupling (AFM+SOC). The structural parameters, bulk moduli, densities of states, and charge distributions have been computed and compared to available experimental data and other theoretical calculations published in the literature. The total energy calculations indicate that the lowest energy structures of AcN, ThN, and PaN are degenerate at the NM+SOC, FM+SOC, and AFM+SOC levels of theory with vanishing total magnetic moments in the FM+SOC and AFM+SOC cases, making the ground states essentially non-magnetic with spin-orbit interaction. The ground states of UN, NpN, PuN, and AmN are found to be FM+SOC at the level of theory used in the present computations. The nature of the interactions between the actinide metals and nitrogen atom, and the implications on 5f electron delocalization and localization are discussed in detail.Comment: 5 tables, 12 figure