7,220 research outputs found

    Friedmann Equations from Entropic Force

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    In this note by use of the holographic principle together with the equipartition law of energy and the Unruh temperature, we derive the Friedmann equations of a Friedmann-Robertson-Walker universe.Comment: latex, 8 pages, v2: minor modifications and to appear in PRD (Rapid Communication

    Modelling the unfolding pathway of biomolecules: theoretical approach and experimental prospect

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    We analyse the unfolding pathway of biomolecules comprising several independent modules in pulling experiments. In a recently proposed model, a critical velocity vcv_{c} has been predicted, such that for pulling speeds v>vcv>v_{c} it is the module at the pulled end that opens first, whereas for v<vcv<v_{c} it is the weakest. Here, we introduce a variant of the model that is closer to the experimental setup, and discuss the robustness of the emergence of the critical velocity and of its dependence on the model parameters. We also propose a possible experiment to test the theoretical predictions of the model, which seems feasible with state-of-art molecular engineering techniques.Comment: Accepted contribution for the Springer Book "Coupled Mathematical Models for Physical and Biological Nanoscale Systems and Their Applications" (proceedings of the BIRS CMM16 Workshop held in Banff, Canada, August 2016), 16 pages, 6 figure

    Deacetyl­nomilin monohydrate

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    In the title compound (systematic name 1-hy­droxy-1,2-dihydro­obacunoic acid 3,4-lactone monohydrate), C26H32O8·H2O, the dihedral angles between the planes of the ester groups and the furan plane are 43.06 (12) and 56.06 (7)°, while that between the furan plane and the keto group is 58.50 (9)°. The A/B, B/C and C/D ring junctions are all trans-fused. Inter­molecular O—H⋯O hydrogen bonds between the hy­droxy and carbonyl groups and the water mol­ecule give rise to a three-dimensional structure

    Highly Damped Quasinormal Modes of Kerr Black Holes: A Complete Numerical Investigation

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    We compute for the first time very highly damped quasinormal modes of the (rotating) Kerr black hole. Our numerical technique is based on a decoupling of the radial and angular equations, performed using a large-frequency expansion for the angular separation constant_{s}A_{l m}. This allows us to go much further in overtone number than ever before. We find that the real part of the quasinormal frequencies approaches a non-zero constant value which does not depend on the spin s of the perturbing field and on the angular index l: \omega_R=m\varpi(a). We numerically compute \varpi(a). Leading-order corrections to the asymptotic frequency are likely to be of order 1/\omega_I. The imaginary part grows without bound, the spacing between consecutive modes being a monotonic function of a.Comment: 5 pages, 3 figure

    Growth mechanisms of GaN microrods for 3D core-shell LEDs: The influence of silane flow

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    The three dimensional growth of GaN structures as a basis for the fabrication of 3D GaN core-shell LEDs has attracted substantial attention in the past years. GaN nanorods or microrods with high aspect ratios can be grown by selective area epitaxy on a GaN buffer through a SiOx mask. It has been found earlier that silane substantially initiates vertical growth, with the exact underlying mechanisms being still unclear. Here, the influence of silane on the 3D GaN column growth was investigated by performing detailed growth experiments in combination with a thorough surface analysis in order to get insight into these mechanisms. The vertical growth rate is significantly enhanced by high silane fluxes, whereas the saturation of growth rate with the time is reduced. Thus, homogenous GaN columns with an aspect ratio of more than 35 could be achieved. A thin Si-rich layer on the non-polar m-plane facets of the columns has been detected using a combination of transmission electron microscopy, energy dispersive X-ray spectroscopy and Auger electron spectroscopy. This layer is suggested to be the reason for the increase in growth rate, modifying the effective collection range of the species along the sidewalls, and preventing the lateral growth

    Stochastic many-particle model for LFP electrodes

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    In the framework of non-equilibrium thermodynamics, we derive a new model for many-particle electrodes. The model is applied to LiFePO4 (LFP) electrodes consisting of many LFP particles of nanometer size. The phase transition from a lithium-poor to a lithium-rich phase within LFP electrodes is controlled by both different particle sizes and surface fluctuations leading to a system of stochastic differential equations. An explicit relation between battery voltage and current controlled by the thermodynamic state variables is derived. This voltage–current relation reveals that in thin LFP electrodes lithium intercalation from the particle surfaces into the LFP particles is the principal rate-limiting process. There are only two constant kinetic parameters in the model describing the intercalation rate and the fluctuation strength, respectively. The model correctly predicts several features of LFP electrodes, viz. the phase transition, the observed voltage plateaus, hysteresis and the rate-limiting capacity. Moreover we study the impact of both the particle size distribution and the active surface area on the voltage–charge characteristics of the electrode. Finally we carefully discuss the phase transition for varying charging/discharging rates

    A Candidate Gene-Based Association Study of Tocopherol Content and Composition in Rapeseed (Brassica napus)

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    Rapeseed (Brassica napus L.) is the most important oil crop of temperate climates. Rapeseed oil contains tocopherols, also known as vitamin E, which is an indispensable nutrient for humans and animals due to its antioxidant and radical scavenging abilities. Moreover, tocopherols are also important for the oxidative stability of vegetable oils. Therefore, seed oil with increased tocopherol content or altered tocopherol composition is a target for breeding. We investigated the role of nucleotide variations within candidate genes from the tocopherol biosynthesis pathway. Field trials were carried out with 229 accessions from a worldwide B. napus collection which was divided into two panels of 96 and 133 accessions. Seed tocopherol content and composition were measured by HPLC. High heritabilities were found for both traits, ranging from 0.62 to 0.94. We identified polymorphisms by sequencing selected regions of the tocopherol genes from the 96 accession panel. Subsequently, we determined the population structure (Q) and relative kinship (K) as detected by genotyping with genome-wide distributed SSR markers. Association studies were performed using two models, the structure-based GLM + Q and the PK-mixed model. Between 26 and 12 polymorphisms within two genes (BnaX.VTE3.a, BnaA.PDS1.c) were significantly associated with tocopherol traits. The SNPs explained up to 16.93% of the genetic variance for tocopherol composition and up to 10.48% for total tocopherol content. Based on the sequence information we designed CAPS markers for genotyping the 133 accessions from the second panel. Significant associations with various tocopherol traits confirmed the results from the first experiment. We demonstrate that the polymorphisms within the tocopherol genes clearly impact tocopherol content and composition in B. napus seeds. We suggest that these nucleotide variations may be used as selectable markers for breeding rapeseed with enhanced tocopherol quality

    Different Roles of BDNF in Nucleus Accumbens Core versus Shell during the Incubation of Cue-Induced Cocaine Craving and Its Long-Term Maintenance

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    Brain-derived neurotrophic factor (BDNF) contributes to diverse types of plasticity, including cocaine addiction. We investigated the role of BDNF in the rat nucleus accumbens (NAc) in the incubation of cocaine craving over 3 months of withdrawal from extended access cocaine self-administration. First, we confirmed by immunoblotting that BDNF levels are elevated after this cocaine regimen on withdrawal day 45 (WD45) and showed that BDNF mRNA levels are not altered. Next, we explored the time course of elevated BDNF expression using immunohistochemistry. Elevation of BDNF in the NAc core was detected on WD45 and further increased on WD90, whereas elevation in shell was not detected until WD90. Surface expression of activated tropomyosin receptor kinase B (TrkB) was also enhanced on WD90. Next, we used viral vectors to attenuate BDNF-TrkB signaling. Virus injection into the NAc core enhanced cue-induced cocaine seeking on WD1 compared with controls, whereas no effect was observed on WD30 or WD90. Attenuating BDNF-TrkB signaling in shell did not affect cocaine seeking on WD1 or WD45 but significantly decreased cocaine seeking on WD90. These results suggest that basal levels of BDNF transmission in the NAc core exert a suppressive effect on cocaine seeking in early withdrawal (WD1), whereas the late elevation of BDNF protein in NAc shell contributes to incubation in late withdrawal (WD90). Finally, BDNF protein levels in the NAc were significantly increased after ampakine treatment, supporting the novel hypothesis that the gradual increase of BDNF levels in NAc accompanying incubation could be caused by increased AMPAR transmission during withdrawal

    Entropy spectrum of a Kerr anti-de Sitter black hole

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    The entropy spectrum of a spherically symmetric black hole was derived without the quasinormal modes in the work of Majhi and Vagenas. Extending this work to rotating black holes, we quantize the entropy and the horizon area of a Kerr anti-de Sitter black hole by two methods. The spectra of entropy and area are obtained via the Bohr-Sommerfeld quantization rule and the adiabatic invariance in the first way. By addressing the wave function of emitted (absorbed) particles, the entropy and the area are quantized in the second one. Both results show that the entropy and the area spectra are equally spaced.Comment: Accepted for publication in The European Physical Journal C, Volume 72, Issue
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