2,169 research outputs found

    Automatic signal range selector for metering devices Patent

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    Voltage range selection apparatus for sensing and applying voltages to electronic instruments without loading signal sourc

    Skill Determination from Long Videos

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    Manderlay (2005): Lars von Trier’s Narrative of Passing

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    Von Trier, the maverick Danish director, has over the course of his career earned a reputation for being difficult; he has a tendency to create films that are not only challenging but demand an active level of participation from his audience. The film Manderlay (2005) continues this tradition of provoking intellectual debate. Whereas numerous scholars and critics have recognised that the film can be read as a metaphorical reference to George W. Bush's invasion of Iraq, this article interprets Manderlay as an allegory for the way African Americans have been represented by the US film industry

    HAPTEN-SPECIFIC STIMULATION OF SECONDARY B CELLS INDEPENDENT OF T CELLS

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    Treatment of spleen cell suspensions from immunized mice with anti-theta serum and complement before transfer to nonimmune irradiated recipients reduced the degree of in vitro stimulation by hapten-homologous carrier complexes by 90%, but did not decrease at all the number of isolated precursor cells stimulated by hapten on heterologous carriers. Thus, secondary B cells can be stimulated by low concentrations of multiply substituted hapten-carrier complexes in the apparent complete absence of specific T cells

    A Golgi and tonoplast localized S-acyl transferase is involved in cell expansion, cell division, vascular patterning and fertility in Arabidopsis

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    S‐acylation of eukaryotic proteins is the reversible attachment of palmitic or stearic acid to cysteine residues, catalysed by protein S‐acyl transferases that share an Asp‐His‐His‐Cys (DHHC) motif. Previous evidence suggests that in Arabidopsis S‐acylation is involved in the control of cell size, polarity and the growth of pollen tubes and root hairs. Using a combination of yeast genetics, biochemistry, cell biology and loss of function genetics the roles of a member of the protein S‐acyl transferase PAT family, AtPAT10 (At3g51390), have been explored. In keeping with its role as a PAT, AtPAT10 auto‐S‐acylates, and partially complements the yeast akr1 PAT mutant, and this requires Cys192 of the DHHC motif. In Arabidopsis AtPAT10 is localized in the Golgi stack, trans‐Golgi network/early endosome and tonoplast. Loss‐of‐function mutants have a pleiotropic phenotype involving cell expansion and division, vascular patterning, and fertility that is rescued by wild‐type AtPAT10 but not by catalytically inactive AtPAT10C192A. This supports the hypothesis that AtPAT10 is functionally independent of the other Arabidopsis PATs. Our findings demonstrate a growing importance of protein S‐acylation in plants, and reveal a Golgi and tonoplast located S‐acylation mechanism that affects a range of events during growth and development in Arabidopsis

    On Semantic Similarity in Video Retrieval

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    Current video retrieval efforts all found their evaluation on an instance-based assumption, that only a single caption is relevant to a query video and vice versa. We demonstrate that this assumption results in performance comparisons often not indicative of models' retrieval capabilities. We propose a move to semantic similarity video retrieval, where (i) multiple videos/captions can be deemed equally relevant, and their relative ranking does not affect a method's reported performance and (ii) retrieved videos/captions are ranked by their similarity to a query. We propose several proxies to estimate semantic similarities in large-scale retrieval datasets, without additional annotations. Our analysis is performed on three commonly used video retrieval datasets (MSR-VTT, YouCook2 and EPIC-KITCHENS).Comment: Accepted in CVPR 2021. Project Page: https://mwray.github.io/SSVR

    Land use influences on acidification and recovery of freshwaters in Galloway, south-west Scotland

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    International audienceThe long term response of surface waters to changes in sulphur deposition and afforestation is investigated for three upland river systems in the Galloway region of south-west Scotland. From 1984-1999, these rivers exhibited a statistically significant decline in non-marine sulphate concentrations in response to reduced acid deposition. This reduction in non-marine sulphate was, however, insufficient to induce a pH recovery over the period. A statistically significant increase in river pH was observed between 1956-1970 (0.05 yr-1) when subsidised agricultural lime payments were at a maximum. In 1976, this subsidy ceased and surface waters have progressively acidified. In addition, climatic change is found to influence long-term trends in pH. Mean annual pH was greatest during a dry period between 1969-1973 when total annual discharge was low. Thereafter, pH declined gradually in response to higher rainfall and increased total annual discharge. Overall, surface waters draining the afforested catchments of the Rivers Cree and Bladnoch are more acid than those draining the moorland catchment of the Luce. These results indicate that in afforested catchments, current reductions in sulphur emissions have not led to an observed improvement in the acid status of surface waters. Forestry, therefore, represents a confounding factor with regard to chemical recovery from acidification in this region. Keywords: acidification, afforestation, deposition, rivers, lochs, non-marine sulphate, p

    2-Methylhopanoids are maximally produced in akinetes of Nostoc punctiforme: geobiological implications

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    2-Methylhopanes, molecular fossils of 2-methylbacteriohopanepolyol (2-MeBHP) lipids, have been proposed as biomarkers for cyanobacteria, and by extension, oxygenic photosynthesis. However, the robustness of this interpretation is unclear, as 2-methylhopanoids occur in organisms besides cyanobacteria and their physiological functions are unknown. As a first step toward understanding the role of 2-MeBHP in cyanobacteria, we examined the expression and intercellular localization of hopanoids in the three cell types of Nostoc punctiforme: vegetative cells, akinetes, and heterocysts. Cultures in which N. punctiforme had differentiated into akinetes contained approximately 10-fold higher concentrations of 2-methylhopanoids than did cultures that contained only vegetative cells. In contrast, 2-methylhopanoids were only present at very low concentrations in heterocysts. Hopanoid production initially increased threefold in cells starved of nitrogen but returned to levels consistent with vegetative cells within 2 weeks. Vegetative and akinete cell types were separated into cytoplasmic, thylakoid, and outer membrane fractions; the increase in hopanoid expression observed in akinetes was due to a 34-fold enrichment of hopanoid content in their outer membrane relative to vegetative cells. Akinetes formed in response either to low light or phosphorus limitation, exhibited the same 2-methylhopanoid localization and concentration, demonstrating that 2-methylhopanoids are associated with the akinete cell type per se. Because akinetes are resting cells that are not photosynthetically active, 2-methylhopanoids cannot be functionally linked to oxygenic photosynthesis in N. punctiforme
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