Franchising And The Internet: An Example of Knowledge Mangement in New Zealand Business

“The newest innovations, which we label information technologies, have begun to alter the manner in which we do business and create value, often in ways not readily foreseeable even five years ago.” [1]. The Internet is a technology that has revolutionised business and the manner in which it is conducted. Recent studies suggest that e-commerce will explode to over US$6 trillion in 2 years time. This paper discusses how the Internet can be used in one particular facet of business: franchising. The manner in which services are provided through the use of Internet sites and the strategies by which these can be implemented are covered, examining the different types of sites, and the roles of the franchisor and franchisee in development. The benefits that can be experienced are outlined, and vary from advertising both the franchise concept and the products or services provided, improving communication between parties, and providing the opportunity for collaborative ventures. Up until now the degree to which the Internet has been adopted by Franchises in New Zealand has been limited, with some notable exceptions. However recent surveys reveal that its acceptance is increasing, and that franchise systems recognise that the use of technology poses opportunities in the years to come

Something’s missing from my education: Using a cross sectional survey to examine the needs and interest of Canadian medical students relating to their roles as teachers and educators

Background: Current theory in medical education emphasizes engaging learners as educators while tailoring teaching to their learning needs. However, little is known about learners’ perceptions of their proposed roles as teachers and educators.Methods: Canadian medical students were invited to complete an English language online questionnaire structured to include: teaching experience, participation and/or awareness of teacher development at their school and awareness and/or interest in further training in medical education. The survey was developed by the Canadian Association for Medical Education (CAME) Membership Subcommittee, and distributed via the Canadian Federation of Medical Students (CFMS) email list and the CAME twitter account in March 2014.Results: Of the 169 undergraduate medical student respondents, 36% (n=61) reported a lack of prior teaching experience and 45% (n=73) were unsure if their school provided teaching instruction. Overall, 91% (n=150) indicated that they planned to incorporate teaching or medical education into their future careers.Conclusion: While the majority of medical student respondents are expecting or planning to teach, most report not having access to adequate training through medical school. Further effort is necessary to support medical students as teachers to prepare them for increased teaching responsibilities as residents and to expose them to potential careers in medical education.

A critical reassessment of the role of mitochondria in tumorigenesis

<p><b>Background:</b> Mitochondrial DNA (mtDNA) is being analyzed by an increasing number of laboratories in order to investigate its potential role as an active marker of tumorigenesis in various types of cancer. Here we question the conclusions drawn in most of these investigations, especially those published in high-rank cancer research journals, under the evidence that a significant number of these medical mtDNA studies are based on obviously flawed sequencing results.</p> <p><b>Methods and Findings:</b> In our analyses, we take a phylogenetic approach and employ thorough database searches, which together have proven successful for detecting erroneous sequences in the fields of human population genetics and forensics. Apart from conceptual problems concerning the interpretation of mtDNA variation in tumorigenesis, in most cases, blocks of seemingly somatic mutations clearly point to contamination or sample mix-up and, therefore, have nothing to do with tumorigenesis.</p> <p><b>Conclusion:</b> The role of mitochondria in tumorigenesis remains unclarified. Our findings of laboratory errors in many contributions would represent only the tip of the iceberg since most published studies do not provide the raw sequence data for inspection, thus hindering a posteriori evaluation of the results. There is no precedent for such a concatenation of errors and misconceptions affecting a whole subfield of medical research.</p&gt

Laboratory Evaluation of Dynamic Routing of Air Traffic in an En Route Arrival Metering Environment

Arrival air traffic operations in the presence of convective weather are subject to uncertainty in aircraft routing and subsequently in flight trajectory predictability. Current management of arrival operations in weather-impacted airspace results in significant flight delay and suspension of arrival metering operations. The Dynamic Routing for Arrivals in Weather (DRAW) concept provides flight route amendment advisories to Traffic Management Coordinators to mitigate the impacts of convective weather on arrival operations. DRAW provides both weather conflict and schedule information for proposed route amendments, allowing air traffic managers to simultaneously evaluate weather avoidance routing and potential schedule and delay impacts. Subject matter experts consisting of retired Traffic Management Coordinators and retired Sector Controllers with arrival metering experience participated in a simulation study of Fort Worth Air Route Traffic Control Center arrival operations. Data were collected for Traffic Management Coordinator and Sector Controller participants over three weeks of simulation activities in October, 2017. Traffic Management Coordinators reported acceptable workload levels, a positive impact on their ability to manage arrival traffic while using DRAW, and initiated weather mitigation reroutes earlier while using DRAW. Sector Controllers also reported acceptable workload levels while using DRAW

Post-Quantum Anonymous Veto Networks

Anonymous veto networks (AV-nets), originally proposed by Hao and Zielinski (2006), are particularly lightweight protocols for evaluating a veto function in a peer-to-peer network such that anonymity of all protocol participants is preserved. Prior to this work, anonymity in all AV-nets from the literature relied on the decisional Diffie-Hellman (DDH) assumption and can thus be broken by (scalable) quantum computers. In order to defend against this threat, we propose two practical and completely lattice-based AV-nets. The first one is secure against passive and the second one is secure against active adversaries. We prove that anonymity of our AV-nets reduces to the ring learning with errors (RLWE) assumption. As such, our AV-nets are the first ones with post-quantum anonymity. We also provide performance benchmarks to demonstrate their practicality

A low density of 0.8 g/cc for the Trojan binary asteroid 617 Patroclus

The Trojan population consists of two swarms of asteroids following the same orbit as Jupiter and located at the L4 and L5 Lagrange points of the Jupiter-Sun system (leading and following Jupiter by 60 degrees). The asteroid 617 Patroclus is the only known binary Trojan (Merline et al. 2001). The orbit of this double system was hitherto unknown. Here we report that the components, separated by 680 km, move around the system centre of mass, describing roughly a circular orbit. Using the orbital parameters, combined with thermal measurements to estimate the size of the components, we derive a very low density of 0.8 g/cc. The components of Patroclus are therefore very porous or composed mostly of water ice, suggesting that they could have been formed in the outer part of the solar system.Comment: 10 pages, 3 figures, 1 tabl

Crop Updates 2000 - Cereals part 1

This session covers eleven papers from different authors: PLENARY PAPERS 1. New Wheat for a Secure, Sustainable Future, Timothy G. Reeves, Sanjaya Rajaram, Maarten van Ginkel, Richard Trethowan, Hans-Joachim Braun, and Kelly Cassaday, International Maize and Wheat Improvement Centre (CIMMYT) 2. Managing Cereal Rusts - a National Perspective, R.A. McIntosh, University of Sydney Plant Breeding Institute, New South Wales 3. Managing Cereal Rusts in 2000 - a regional imperative, R. Loughman, Agriculture Western Australia 4. Is nutrition the answer to wheat after canola problems?Ross Brennan1, Bill Bowden1, Mike Bolland1, Zed Rengel2 and David Isbister2 1 Agriculture Western Australia 2University of Western Australia 5. Improved Sandplain Cropping Systems by Controlled Traffic, Dr Paul Blackwell, Agriculture Western Australia 6. Raised bed farming for improved cropping of waterlogged soils, Derk Bakker, Greg Hamilton, David Houlbrooke, Cliff Spann and Doug Rowe, Agriculture Western Australia 7. Banded Urea increased wheat yields, Patrick Gethin, Stephen Loss, Frank Boetel, and Tim O’Dea, CSBP futurefarm 8. Flexi N is as effective as Urea on wheat and canola, Frank Boetel, Stephen Loss, Patrick Gethin, and Tim O’Dea CSBP futurefarm 9. Why potassium may reduce cereal leaf disease, Noeleen Edwards, Agriculture Western Australia 10, Trace elements, Wayne Pluske CSBP futurefarm, and Ross BrennanAgriculture Western Australia 11. Historical Nutrient Balance at Paddock and Whole Farm scales for typical wheatbelt farms in the Dowerin - Wongan Hills area, M.T.F. Wong, K. Wittwer and H. Zhang Precision Agriculture Research Group, CSIRO Land and Wate

Salivary and lacrimal dysfunction after radioactive iodine for differentiated thyroid cancer: American Head and Neck Society Endocrine Surgery Section and Salivary Gland Section joint multidisciplinary clinical consensus statement of otolaryngology, ophthalmology, nuclear medicine and endocrinology

BackgroundPostoperative radioactive iodine (RAI) administration is widely utilized in patients with differentiated thyroid cancer. While beneficial in select patients, it is critical to recognize the potential negative sequelae of this treatment. The prevention, diagnosis, and management of the salivary and lacrimal complications of RAI exposure are addressed in this consensus statement.MethodsA multidisciplinary panel of experts was convened under the auspices of the American Head and Neck Society Endocrine Surgery and Salivary Gland Sections. Following a comprehensive literature review to assess the current best evidence, this group developed six relevant consensus recommendations.ResultsConsensus recommendations on RAI were made in the areas of patient assessment, optimal utilization, complication prevention, and complication management.ConclusionSalivary and lacrimal complications secondary to RAI exposure are common and need to be weighed when considering its use. The recommendations included in this statement provide direction for approaches to minimize and manage these complications.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/163491/2/hed26417.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/163491/1/hed26417_am.pd

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

This integrated, multiplatform PanCancer Atlas study co-mapped and identified distinguishing molecular features of squamous cell carcinomas (SCCs) from five sites associated with smokin

Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context

Long noncoding RNAs (lncRNAs) are commonly dys-regulated in tumors, but only a handful are known toplay pathophysiological roles in cancer. We inferredlncRNAs that dysregulate cancer pathways, onco-genes, and tumor suppressors (cancer genes) bymodeling their effects on the activity of transcriptionfactors, RNA-binding proteins, and microRNAs in5,185 TCGA tumors and 1,019 ENCODE assays.Our predictions included hundreds of candidateonco- and tumor-suppressor lncRNAs (cancerlncRNAs) whose somatic alterations account for thedysregulation of dozens of cancer genes and path-ways in each of 14 tumor contexts. To demonstrateproof of concept, we showed that perturbations tar-geting OIP5-AS1 (an inferred tumor suppressor) andTUG1 and WT1-AS (inferred onco-lncRNAs) dysre-gulated cancer genes and altered proliferation ofbreast and gynecologic cancer cells. Our analysis in-dicates that, although most lncRNAs are dysregu-lated in a tumor-specific manner, some, includingOIP5-AS1, TUG1, NEAT1, MEG3, and TSIX, synergis-tically dysregulate cancer pathways in multiple tumorcontexts