243 research outputs found

    Comptes rendus/Reviews

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    Performance of the Ultra-High Rate Germanium (UHRGe) System

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    Performance of the Ultra-High Rate Germanium (UHRGe) System client repor

    CARACTERÍSTICAS DO MÚSCULO LONGISSIMUS DORSI DE CORDEIROS TEXEL ALIMENTADOS COM DIFERENTES NÍVEIS DE SILAGEM DE CASCA DE MANDIOCA

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    Na região sul do Estado de Santa Catarina há grande produção de polvilho de mandioca (Manihot sculenta Crantz), sendo que um dos subprodutos da industrialização deste é a casca de mandioca, a qual se conservada sob a forma de silagem pode ser utilizada na alimentação de ruminantes, podendo ser boa alternativa de volumoso na alimentação animal. O experimento foi realizado no Instituto Federal Catarinense de Educação, Ciência e Tecnologia – Campus Sombrio/SC, foram utilizadas as instalações de confinamento do Setor de Ovino-caprinocultura desta unidade. Foram utilizados 16 cordeiros com predominância da raça Texel recém desmamados, os quais foram distribuídos em quatro tratamentos, com quatro repetições. Após o confinamento dos cordeiros que perdurou por 61 dias estes foram abatidos. Após o resfriamento das carcaças por 24 horas essas foram serradas ao meio. Na meia carcaça esquerda na altura da 12 e 13ª costelas foi exposto o músculo Longissimus dorsi para determinação da área de olho de lombo (AOL), medida que expressa a musculosidade existente na carcaça, também foi avaliada a espessura de gordura subcutânea (EGS) da carcaça máxima e mínima, comprimento e largura máxima do músculo Longissimus dorsi. A área de olho de lombo foi semelhante (P>0,05) entre os tratamentos, com valores médios de 11,94 cm². As medidas do músculo Longissimus dorsi não foram influenciadas pela substituição da silagem de milho da fração volumosa da dieta por silagem de casca de mandioca na alimentação de cordeiros com predominância de sangue Texel

    Rare Copy Number Variants in \u3cem\u3eNRXN1\u3c/em\u3e and \u3cem\u3eCNTN6\u3c/em\u3e Increase Risk for Tourette Syndrome

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    Tourette syndrome (TS) is a model neuropsychiatric disorder thought to arise from abnormal development and/or maintenance of cortico-striato-thalamo-cortical circuits. TS is highly heritable, but its underlying genetic causes are still elusive, and no genome-wide significant loci have been discovered to date. We analyzed a European ancestry sample of 2,434 TS cases and 4,093 ancestry-matched controls for rare (\u3c 1% frequency) copy-number variants (CNVs) using SNP microarray data. We observed an enrichment of global CNV burden that was prominent for large (\u3e 1 Mb), singleton events (OR = 2.28, 95% CI [1.39–3.79], p = 1.2 × 10−3) and known, pathogenic CNVs (OR = 3.03 [1.85–5.07], p = 1.5 × 10−5). We also identified two individual, genome-wide significant loci, each conferring a substantial increase in TS risk (NRXN1 deletions, OR = 20.3, 95% CI [2.6–156.2]; CNTN6 duplications, OR = 10.1, 95% CI [2.3–45.4]). Approximately 1% of TS cases carry one of these CNVs, indicating that rare structural variation contributes significantly to the genetic architecture of TS

    Protocol for the Arterial Revascularisation Trial (ART). A randomised trial to compare survival following bilateral versus single internal mammary grafting in coronary revascularisation [ISRCTN46552265]

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    BACKGROUND: Standard coronary artery bypass graft surgery uses a single internal mammary artery and supplemental vein or radial artery grafts. Several observational studies have suggested a survival benefit with two internal mammary artery grafts compared to a single internal mammary artery graft, but this has not been tested in a randomised trial. The Arterial Revascularisation Trial is a Medical Research Council and British Heart Foundation funded, multi-centre international trial comparing single internal mammary artery grafting versus bilateral internal mammary artery grafting. METHODS/DESIGN: Twenty centres in the UK, Australia, Poland and Brazil are planning to randomise 3000 coronary artery bypass graft surgery patients to single or bilateral internal mammary artery grafting. Supplemental grafts may be either saphenous vein or radial artery. Coronary artery bypass grafting can be performed as an on-pump or off-pump procedure. The primary outcome is survival at 10 years and secondary end-points include clinical events, quality of life and cost effectiveness. The effect of age, left ventricular function, diabetes, number of grafts, vein grafts and off-pump surgery are pre-specified subgroups. DISCUSSION: The Arterial Revascularisation Trial is one of the first randomised trials to evaluate the effects on survival and other clinical outcomes of single internal mammary artery grafting versus bilateral internal mammary artery grafting, and will help to establish the best approach for patients requiring coronary artery bypass graft surgery

    The relationship between teacher perceptions of pupil attractiveness and academic ability.

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    There is an established literature that suggests teacher perceptions of pupils affect how they interact with them, how they teach them and how they rate their ability and behaviour. Evidence also indicates that a teacher’s perception of a child is often based on ascriptive characteristics such as gender, ethnicity and socio-economic background independent of a child’s ability. This paper builds on the literature by examining the relationship between teacher perceptions of a child’s ability and behaviour and their perceptions of a particular ascriptive characteristic of those children - their attractiveness. Using data from the National Child Development Study (NCDS) results show that not only do teachers rate the academic ability of pupils they perceive to be attractive more highly than less attractive students both in terms of their performance across different areas of learning (general knowledge, numbers, books and oral ability) and whether they show any outstanding potential but they are also more likely to over rate and less likely to under rate their ability than other students. This is true even after controlling for a wide range of other factors related to the child, their family, their teacher and their school that could influence the relationship, many of which are shown to be independently related to teacher’s ratings
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