Loading Time Flexibility in Cross-Docking Systems

In this study, we investigate truck-to-door assignment problem for loading outgoing trucks in a cross-docking system with flexible handling times. Specifically, a truck\u27s loading time depends on the number of workers assigned to the outbound door, where the truck is being loaded. An optimization problem is formulated to jointly determine the number of workers and the trucks to be loaded at each door. The resulting problem is a nonlinear integer programming model. Due to the complexity of this model, two evolutionary heuristic methods are proposed for solution. First heuristic method is based on truck assignments while the second heuristic is based on worker assignments. A numerical study is conducted to compare the two heuristic methods

Complete Multiwavelength Evolution of Galactic Black Hole Transients During Outburst Decay II: Compact Jets and X-ray Variability Properties

We investigated the relation between compact jet emission and X-ray variability properties of all black hole transients with multiwavelength coverage during their outburst decays. We studied the evolution of all power spectral components (including low frequency quasi-periodic oscillations), and related this evolution to changes in jet properties tracked by radio and infrared observations. We grouped sources according to their tracks in radio/X-ray luminosity relation, and show that the standards show stronger broadband X-ray variability than outliers at a given X-ray luminosity when the compact jet turned on. This trend is consistent with the internal shock model and can be important for the understanding of the presence of tracks in the radio/X-ray luminosity relation. We also observed that the total and the QPO rms amplitudes increase together during the earlier part of the outburst decay, but after the compact jet turns either the QPO disappears or its rms amplitude decreases significantly while the total rms amplitudes remain high. We discuss these results with a scenario including a variable corona and a non-variable disk with a mechanism for the QPO separate from the mechanism that create broad components. Finally, we evaluated the timing predictions of the magnetically dominated accretion flow model which can explain the presence of tracks in the radio/X-ray luminosity relation.Comment: Accepted for publication by Ap

In vitro transfection of HeLa cells with temperature sensitive polycationic copolymers

Cataloged from PDF version of article.In this study, we investigated different types of polyethyleneimine (PEI) and their block copolymers with N-isopropylacrylamide (NIPA) as temperature-sensitive polycationic non-viral vectors for transfection of HeLa cells in cell culture media. First carboxyl-terminated poly(NIPA) was synthesized and then copolymerized with PEIs branched or linear and with two different molecular weights (2 and 25 kDa). Addition of PEI units to the poly(NIPA) chains increased the LCST values up to body temperature. Zeta potentials of the copolymers were significantly lower than the corresponding PEI homopolymers. A green fluorescent protein expressing plasmid was used as a model. Complexes of this plasmid both with PEIs and their copolymers were formed. The zeta potentials of these complexes were between -3.1 and +21.3. Higher values were observed for the complexes prepared with branched and higher molecular weight PEIs. Copolymerization caused a profound decrease in the positive charges. Particle sizes of the complexes were in the range of 190-1235 nm. Using high polymer/plasmid ratios caused aggregation. The smallest complexes were obtained with the copolymer prepared with branched PEI with 25-kDa molecular weight. Copolymers were able to squeeze plasmid DNA more at the body temperature. Cytotoxicity was observed with PEIs especially with the branched higher molecular weights. Copolymerization reduced the cytotoxicity. The best in vitro DNA uptake efficiency (70%) was achieved with the complex prepared with poly(NIPA)/PEI25B. However, poly(NIPA)/PEI25L was the most successful vector for an effective gene expression without any significant toxicity. © 2004 Elsevier B.V. All rights reserved

Wind, jet, hybrid corona and hard X-ray flares: multiwavelength evolution of GRO J1655-40 during the 2005 outburst rise

We have investigated the complex multiwavelength evolution of GRO J1655-40 during the rise of its 2005 outburst. We detected two hard X-ray flares, the first one during the transition from the soft state to the ultra-soft state, and the second one in the ultra-soft state. The first X-ray flare coincided with an optically thin radio flare. We also observed a hint of increased radio emission during the second X-ray flare. To explain the hard flares without invoking a secondary emission component, we fit the entire data set with the eqpair model. This single, hybrid Comptonization model sufficiently fits the data even during the hard X-ray flares if we allow reflection fractions greater than unity. In this case, the hard X-ray flares correspond to a Comptonizing corona dominated by non-thermal electrons. The fits also require absorption features in the soft and ultra-soft state which are likely due to a wind. In this work we show that the wind and the optically thin radio flare co-exist. Finally, we have also investigated the radio to optical spectral energy distribution, tracking the radio spectral evolution through the quenching of the compact jet and rise of the optically thin flare, and interpreted all data using state transition models.Comment: 16 pages, 11 figure

SWARM PARAMETERS IN ELECTRONEGATIVE GASES.

Uniform field steady state ionization growth currents are measured in SF(,6), N(,2) and SF(,6) + N(,2) mixtures over the E/p range 60-450 V cm(\u27-1) Torr(\u27-1). Analysis of ionization growth currents provided quantitative data on effective ionization, ionization and attachment coefficients. The variation of effective ionization coefficient in SF(,6) + N(,2) mixtures is found to be nonlinear with the percentage mixture ratio. It is observed that at a given electric field to gas pressure ratio, the effective ionization coefficient decreases with increasing SF(,6) component in the mixture. This reduction in the effective ionization coefficient becomes relatively higher as E/p decreases. However, once a certain concentration of SF(,6) in the mixture is reached, further addition of SF(,6) responds with relatively little effect on the reduction. The same behaviour is observed for spark over voltage measurements. Variation of spark over voltage with SF(,6) concentration shows saturation tendency particularly at high pd (cm-torr) levels. The data for effective ionization, ionization and attachment coefficients is also obtained in CCl(,2)F(,2) + CO(,2) electronegative gas mixtures where it is again observed that the variation of the effective ionization coefficient with respect to mixture percentage ratio is nonlinear at a given E/p in the interval 100 (LESSTHEQ) E/p (LESSTHEQ) 180 V cm(\u27-1) torr(\u27-1). A Monte-Carlo simulation technique is used to provide swarm data in SF(,6). The swarm parameters evaluated are compared with the experimental values of drift velocity, ratio of radial diffusion coefficient to mobility, ionization and attachment coefficients available in the literature. The electron-molecule collision cross sections adopted in the simulation resulted in good agreement with the experimental values over the E/p range of interest 100 (LESSTHEQ) E/p (LESSTHEQ) 180 V cm(\u27-1) Torr(\u27-1). The simulation is also extended to EXB uniform fields to observe the effect of perpendicularly applied magnetic fields on the swarm parameters of SF(,6).Dept. of Electrical and Computer Engineering. Paper copy at Leddy Library: Theses & Major Papers - Basement, West Bldg. / Call Number: Thesis1985 .D553. Source: Dissertation Abstracts International, Volume: 46-08, Section: B, page: 2753. Thesis (Ph.D.)--University of Windsor (Canada), 1985

Sonocrystallisation of Lactose in an Aqueous System

Although research on sonocrystallisation of lactose has been reported in the literature (yield and crystal size), the effect of ultrasound variables on nucleation and growth rate of lactose have not been studied. In this study, lactose crystallisation with ultrasound was compared with mechanical agitation using the induction time method at 22 °C. Ultrasound had a significant effect in reducing induction times and narrowing the metastable zone width but had no effect on individual crystal growth rate or morphology. A rapid decrease in induction time was observed up to 0.46 Wg-1 power density. Sonication up to 3 min decreased the induction time, but no further reduction was observed beyond 3 min. It was not possible to generate the nucleation rates achieved by sonication using agitation alone. 1 min sonication at 0.46 Wg1 power density followed by continuous stirring was found to be the optimum under the experimental conditions tested

Multiwavelength observations of the black hole transient XTE J1752-223 during its 2010 outburst decay

Galactic black hole transients show many interesting phenomena during outburst decays. We present simultaneous X-ray (RXTE, Swift, and INTEGRAL), and optical/near-infrared (O/NIR) observations (SMARTS), of the X-ray transient, XTE J1752-223 during its outburst decay in 2010. The multi- wavelength observations of 150 days in 2010 cover the transition from soft to hard spectral state. The evolution of ATCA/VLBI radio observations are shown to confirm the compact jet appearance. The source shows flares in O/NIR during changes in X-ray and radio properties. One of those flares is bright and long, and starts about 20 days after the transition in timing. Other, smaller flares occur along with the transition in timing and increase in power-law flux, and also right after the detection of the core with VLBI. Furthermore, using the simultaneous broadband X-ray spectra including IN- TEGRAL, we found that a high energy cut-off is necessary with a folding energy at around 250 keV around the time that the compact jet is forming. The broad band spectrum can also be fitted equally well with a Comptonization model. In addition, using photoelectric absorption edges in the XMM– Newton RGS X-ray spectra and the extinction of red clump giants in the direction of the source, we found a lower limit on the distance of > 5 kpc

An integrated evaluation of facility location, capacity acquisition, and technology selection for designing global manufacturing strategies

Emergence of global markets enhanced the emergence of global firms which have plants in different countries and implement an integrated management style. Due to the intensive competition in global markets, manufacturing performance is conceived as an important strategic weapon. Facility location, capacity acquisition and technology selection decisions constitute means to implement manufacturing strategies. We review the literature in order to contribute to a better understanding of global manufacturing strategies. As a result we observe that an integrated analysis of the location, capacity and technology decisions is vital for the design of effective global manufacturing strategies. © 1992

The Okavango; a river supporting its people, environment and economic development

The Okavango basin comprises the Cuito and Cubango active catchment areas in Angola, in addition to the Kavango–Okavango non-active catchment in northern Namibia and Botswana. The Okavango River water and its ecosystem resources are critically important sources of livelihoods for people in the basin. Pressures from livelihoods and development are already impacting on the environment. These pressures may increase in the future due to the rapid increase in population, the peace process and associated resettlement activities in Angola, and major development initiatives in Botswana and Namibia. For instance, possible future increase in water abstraction from the Okavango River may affect the long-term environmental sustainability of the Okavango Delta by minimizing channel shifting and thereby reducing spatial biodiversity. The paper argues that while conservation of the natural environment is critical, the pressing development needs must be recognized. The reduction of poverty within the basin should be addressed in order to alleviate adverse effects on the environment. The paper recommends that the development of sustainable tourism and community-based natural resource management initiatives may be appropriate strategies for reaching the Millennium Development Goals of poverty alleviation and achievement of environmental sustainability in the Okavango Basin. These initiatives have a comparative advantage in this area as demonstrated by the performance of the existing projects