87 research outputs found
A low phase noise cavity transmission self-injection locked laser system for atomic physics experiments
Lasers with high spectral purity are indispensable for optical clocks and
coherent manipulation of atomic and molecular qubits for applications such as
quantum computing and quantum simulation. Stabilisation of the laser to a
reference can provide a narrow linewidth and high spectral purity. However,
widely-used diode lasers exhibit fast phase noise that prevents high fidelity
qubit manipulation. Here we demonstrate a self-injection locked diode laser
system utilizing a medium finesse cavity. The cavity not only provides a stable
resonance frequency, but at the same time acts as a low-pass filter for phase
noise beyond the cavity linewidth of around 100 kHz, resulting in low phase
noise from dc to the injection lock limit.
We model the expected laser performance and benchmark it using a single
trapped Ca-ion as a spectrum analyser. We show that the fast phase
noise of the laser at relevant Fourier frequencies of 100 kHz to >2 MHz is
suppressed to a noise floor of between -110 dBc/Hz and -120 dBc/Hz, an
improvement of 20 to 30 dB over state-of-the-art Pound-Drever-Hall-stabilized
extended-cavity diode lasers. This strong suppression avoids incoherent
(spurious) spin flips during manipulation of optical qubits and improves
laser-driven gates in using diode lasers with applications in quantum logic
spectroscopy, quantum simulation and quantum computation.Comment: 10 pages, 4 figure
Coherent photo-thermal noise cancellation in a dual-wavelength optical cavity for narrow-linewidth laser frequency stabilisation
Optical resonators are used for the realisation of ultra-stable frequency lasers. The use of high reflectivity multi-band coatings allows the frequency locking of several lasers of different wavelengths to a single cavity. While the noise processes for single wavelength cavities are well known, the correlation caused by multi-stack coatings has as yet not been analysed experimentally. In our work, we stabilise the frequency of a 729 nm and a 1069 nm laser to one mirror pair and determine the residual-amplitude modulation (RAM) and photo-thermal noise (PTN). We find correlations in PTN between the two lasers and observe coherent cancellation of PTN for the 1069 nm coating. We show that the fractional frequency instability of the 729 nm laser is limited by RAM at 1 × 10−14. The instability of the 1069 nm laser is at 3 × 10−15 close to the thermal noise limit of 1.5 × 10−1
Coherent photo-thermal noise cancellation in a dual-wavelength optical cavity for narrow-linewidth laser frequency stabilisation
Optical resonators are used for the realisation of ultra-stable frequency
lasers. The use of high reflectivity multi-band coatings allows the frequency
locking of several lasers of different wavelengths to a single cavity. While
the noise processes for single wavelength cavities are well known, the
correlation caused by multi-stack coatings has as yet not been analysed
experimentally. In our work, we stabilise the frequency of a nm and a
nm laser to one mirror pair and determine the residual-amplitude
modulation (RAM) and photo-thermal noise (PTN). We find correlations in PTN
between the two lasers and observe coherent cancellation of PTN for the
nm coating. We show that the fractional frequency instability of the
nm laser is limited by RAM at . The instability of the
nm laser is at close to the thermal noise limit of
.Comment: 17 pages, 5 figure
Mega-analysis of association between obesity and cortical morphology in bipolar disorders:ENIGMA study in 2832 participants
Background: Obesity is highly prevalent and disabling, especially in individuals with severe mental illness including bipolar disorders (BD). The brain is a target organ for both obesity and BD. Yet, we do not understand how cortical brain alterations in BD and obesity interact. Methods: We obtained body mass index (BMI) and MRI-derived regional cortical thickness, surface area from 1231 BD and 1601 control individuals from 13 countries within the ENIGMA-BD Working Group. We jointly modeled the statistical effects of BD and BMI on brain structure using mixed effects and tested for interaction and mediation. We also investigated the impact of medications on the BMI-related associations. Results: BMI and BD additively impacted the structure of many of the same brain regions. Both BMI and BD were negatively associated with cortical thickness, but not surface area. In most regions the number of jointly used psychiatric medication classes remained associated with lower cortical thickness when controlling for BMI. In a single region, fusiform gyrus, about a third of the negative association between number of jointly used psychiatric medications and cortical thickness was mediated by association between the number of medications and higher BMI. Conclusions: We confirmed consistent associations between higher BMI and lower cortical thickness, but not surface area, across the cerebral mantle, in regions which were also associated with BD. Higher BMI in people with BD indicated more pronounced brain alterations. BMI is important for understanding the neuroanatomical changes in BD and the effects of psychiatric medications on the brain.</p
Predicting spring phenology in deciduous broadleaf forests: NEON phenology forecasting community challenge
480181-19C90 - Virginia Polytechinic Institute and State University; National Science FoundationPublished versio
Limits to reproduction and seed size-number trade-offs that shape forest dominance and future recovery
International audienceThe relationships that control seed production in trees are fundamental to understanding the evolution of forest species and their capacity to recover from increasing losses to drought, fire, and harvest. A synthesis of fecundity data from 714 species worldwide allowed us to examine hypotheses that are central to quantifying reproduction, a foundation for assessing fitness in forest trees. Four major findings emerged. First, seed production is not constrained by a strict trade-off between seed size and numbers. Instead, seed numbers vary over ten orders of magnitude, with species that invest in large seeds producing more seeds than expected from the 1:1 trade-off. Second, gymnosperms have lower seed production than angiosperms, potentially due to their extra investments in protective woody cones. Third, nutrient-demanding species, indicated by high foliar phosphorus concentrations, have low seed production. Finally, sensitivity of individual species to soil fertility varies widely, limiting the response of community seed production to fertility gradients. In combination, these findings can inform models of forest response that need to incorporate reproductive potential
Limits to reproduction and seed size-number tradeoffs that shape forest dominance and future recovery
The relationships that control seed production in trees are fundamental to understanding the evolution of forest species and their capacity to recover from increasing losses to drought, fire, and harvest. A synthesis of fecundity data from 714 species worldwide allowed us to examine hypotheses that are central to quantifying reproduction, a foundation for assessing fitness in forest trees. Four major findings emerged. First, seed production is not constrained by a strict trade-off between seed size and numbers. Instead, seed numbers vary over ten orders of magnitude, with species that invest in large seeds producing more seeds than expected from the 1:1 trade-off. Second, gymnosperms have lower seed production than angiosperms, potentially due to their extra investments in protective woody cones. Third, nutrient-demanding species, indicated by high foliar phosphorus concentrations, have low seed production. Finally, sensitivity of individual species to soil fertility varies widely, limiting the response of community seed production to fertility gradients. In combination, these findings can inform models of forest response that need to incorporate reproductive potential
Monosaccharide anhydrides (MA) records of Lake El'gygytgyn sediments (MIS 5e, 6, 7e, 8,11c, 12c)
We freeze-dried and homogenized 44 samples of c. 0.7-1.8 g dry sediment from core PG1351 covering late glacials and interglacials of MIS 8 to MIS 5e, integrating sediment of 1 cm core depth. Temporal resolution of these samples ranges from 140 to 960 years per sample. For the period between 430 and 405 kyrs ago (end of MIS 12 to MIS 11c), 13 samples of 0.5-1.3 g of dry sediment from ICDP core 5011-1 were taken for MA analyses, integrating sediment of 2 cm core depth. Eight of these 13 samples are from the same core depths as were previously analysed for pollen (Melles et al., 2012). Temporal resolution of these samples varies between 200 and 970 years per sample comparable to core PG1351. Across all samples, temporal resolution is 333 ± 273 years per sample, giving centennial- to millennial scale averages.
We extracted the polar lipids of all MA samples using a Dionex Accelerated Solvent Extraction system (ASE 350, ThermoFisher Scientific) at 100°C, 103 bar pressure and two extraction cycles (20 min static time) with 100 % methanol, after an ASE cycle with 100 % dichloromethane. For every sample sequence (n=13-18), we extracted a blank ASE cell and included it in all further steps. We added 60 ng of deuterated levoglucosan (C6H3D7O5; dLVG; Th. Geyer GmbH & Co. KG) as internal standard, and filtered the extract over a PTFE filter using acetonitrile and 5 % HPLC-grade water. We analysed the extracts with an Ultimate 3000 RS ultra-high performance liquid chromatograph (U-HPLC) with thermostated autosampler and column oven coupled to a Q Exactive Plus Orbitrap mass spectrometer (Quadrupole-Orbitrap MS; ThermoFisher Scientific) with heated electrospray injection (HESI) probe at GFZ Potsdam, using measurement conditions adapted from earlier studies (Hopmans et al., 2013;Schreuder et al., 2018;Dietze et al., 2019). Briefly, separation was achieved on two Xbridge BEH amide columns in series (2.1 x 150 mm, 3.5 um particle size) fitted with a 50 mm pre-column of the same material (Waters). The compounds were eluted (flow rate 0.2 mL min-1) with 100 % A for 15 minutes, followed by column cleaning with 100 % B for 15 min, and re-equilibration to starting conditions for 25 min. Eluent A was acetonitrile:water:triethylamine (92.5:7.5:0.01) and eluent B acetonitrile:water:triethylamine (70:30:0.01). HESI settings were as follows: sheath gas (N2) pressure 20 (arbitrary units), auxiliary gas (N2) pressure 3 (arbitrary units), auxiliary gas (N2) temperature of 50 ˚C, spray voltage -2.9 kV (negative ion mode), capillary temperature 300 °C, S-Lens 50 V. Detection was achieved by monitoring m/z 150-200 with a resolution of 280,000 ppm. Targeted data dependent MS2 (normalized collision energy 13 V) was performed on any signal within 10 ppm of m/z 161.0445 (calculated exact mass of deprotonated levoglucosan and its isomers) or m/z 168.0884 (calculated exact mass of deprotonated dLVG) with an isolation window of 0.4 m/z. The detection limit was 2.5 pg on column, based on injections of 0.5 to 5000 pg on column of authentic standards of LVG, MAN, and GAL (Santa Cruz Biotechnology) and dLVG.
Integrations were performed on mass chromatograms within 3 ppm mass accuracy and corrected for relative response factors to dLVG (1.08 ± 0.10, 0.76 ± 0.10 and 0.24 ± 0.05 for LVG, MAN, and GAL, respectively), according to known authentic standard mixes injected before and after every measurement sequence and supported by characteristic isomer-specific MS² data. All samples were corrected by subtracting the maximum MA concentrations in the blank duplicates of each ASE sequence. To account for biases due to sediment properties and sedimentation rates, MA influxes (mass accumulation rates in ng cm-2 yr-1) were calculated by multiplying the concentrations (ng g-1) with the sample-specific dry bulk densities (Melles et al., 2007;Wennrich et al., 2016), and the sample's sedimentation rates (cm yr-1) using the age-depth models presented by Nowaczyk et al. (2013) for the the PG1351 and the ICDP-5011-1 cores
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