This dissertation aims to evaluate the impact of improved rice varieties and farmer training programs that have been introduced to boost local rice production in The Gambia. Rice is the main staple crop of The Gambia. The per capita consumption level of rice is estimated at 117 kg per annum, which is one of the highest in sub-Saharan Africa. The annual consumption of rice is estimated at 195, 811 metric tons, out of which only 51,137 metric tons are produced nationally. This huge deficit is met through imports, at an estimated cost of about US50millionannually.Asaresult,thegovernmentiscommittedtoattainingriceself−sufficiency.Toachievethisobjective,currentseffortshaveconcentratedontheintroductionofyieldincreasingimprovedricevarietiesandfarmertrainingprograms.Toevaluatehowsuchimprovedricevarietiesandfarmertrainingprogramsarecontributingtowardstheachievementofriceself−sufficiencyinTheGambiaisthemainfocusofthisdissertation.Toevaluatetheimpactofimprovedricevarietiesandfarmertrainingprograms,thisstudyhasobtainedacountry−widedatafromricegrowingcommunitiesandhouseholdsthatwereselectedthroughamulti−stagestratifiedrandomsamplingprocedure.Datawereobtainedduring2006and2010ricecroppingseasons.Thedatacollectedwereusedtoaddressthreeresearchtopics:(1)Howaccessibilitytoseedsaffectsthepotentialadoptionofanimprovedricevariety:ThecaseofTheNewRiceforAfrica(NERICA)inTheGambia,(2)TheimpactofNewRiceforAfrica(NERICA)adoptiononhouseholdfoodsecurityandhealthinTheGambia,and(3)TheimpactofagriculturaltrainingontechnicalefficiencyofsmallholderriceproducersinTheGambia.Theseresearchtopicsarethemainpillarsofthisdissertation.TheaimofthefirstresearchtopicwastoassessthepopulationadoptionrateofNERICAanditsdeterminants.TheNERICAisahighyieldingricevarietythatwasofficiallyintroducedinTheGambiain2003.TheintroductionofNERICAwasanattempttakenbythegovernmenttoincreasericeproductionandproductivityinthecountry.ThisstudyfocusesontwomainconstraintsthatlimittheadoptionofNERICA:awarenessandaccesstoitsseeds.WeusedthetreatmentevaluationtechniquetoaddresstheseconstraintsandestimatethetruepopulationadoptionrateofNERICAinTheGambia.TheresultsofouranalysisshowthattheNERICApopulationadoptionratecouldhavebeen76Wefoundfarmercontactwithextensionservicesandaccesstoin−kindcreditassignificantdeterminantsofaccesstoandadoptionofNERICAvarieties.Thepolicyimplicationofthesefindingsistoincreasefarmercontactwithextensionandfacilitateaccesstoin−kindcreditserviceslikeimprovedseedstoallthericefarmingcommunities.ThisislikelytoincreaseawarenessandaccesstoNERICAseeds,whichcanhelptosignificantlyclosethepopulationadoptiongapofNERICAinTheGambia.Moreover,wheneffortsaremadetomaketheentirericefarmingpopulationawareoftheexistenceofNERICAvarietiesandalsomaketheseedsofNERICAaccessibletoallricefarmers,thenitwillnotbemeaningfulforfutureresearchtoattempttofurtherestimatepopulationadoptionrateofNERICAinTheGambia.Undersuchcircumstance,amoremeaningfulestimateofadoptionisgivenbyassessingtheintensityoftechnologyuseamongadopters.ForthecaseofNERICAvarieties,itwillbemoreinterestingtoknowtheshareoftotalriceareafamersareallocatingtoNERICAvarieties.ThiswillgiveabetterpictureregardingthedesirabilityoftheNERICAtechnologybythetargetricefarmingpopulation.ThesecondresearchtopicattemptstoidentifyimprovementsinhouseholdfoodsecurityandhealthoutcomeindicatorsthatcanbeattributedtoNERICAadoption.Weusedfoodconsumptionscores(FCS)andsickdayspercapitaamongfarmhouseholdsmembersasoutcomeindicatorsoffoodsecurityandhealth,respectively.SinceNERICAadoptionisadecisionmadebyricefarmers,weassumethatthisselectiondecisionispartlybasedonunobservablefactors,forexample,farmersattitudetowardswork.Therefore,weusedtheinstrumentalvariableapproachtoidentifycausaleffectsofNERICAadoptiononfoodsecurityandhealth.Theresultsofouranalysisshowsignificantdifferencesinsomekeysocio−economicanddemographiccharacteristicsbetweenNERICAadoptersandnon−adopters.Theseadoptinghouseholds.However,theresultsofouranalysishaveshownnosignificantimpactofNERICAadoptiononhealth.Thiscouldbeattributedtothefactthatweusedinformationonallhouseholdmemberstocreatenumberofsickdayspercapita.Giventhelimitedscopeofthesurveydataregardinghealth,morepreciseindicatorsofhealth,suchasdetailedindividualrecalldataonspecificdiseases,anthropometricdata,orotherhealthindicatorswerenotavailable.Numberofsickdayspercapitaisahighlynoisyindicatorwhichtendtobenegativelycorrelatedwithhouseholdsize.Whenoneindividualrespondentreportsonthehealthstatusofallhouseholdsmembers,itcanleadtounderestimationifthehouseholdislarge.Forthisreason,werecommendthatfuturestudiesthatintendtoidentifytheimpactofNERICAadoptiononhealthshouldfocusonindividualrecalldata,whichmaybeabetteroutcomeindicator.Finally,thethirdresearchtopicaimstoidentifyimprovementsintechnicalefficiencyofsmallholderricefarmersthatcanbeattributedtoagriculturalricefarmertrainingprogramsintroducedinTheGambiatoincreasericeproductionandproductivity.Technicalefficiencyisameasureofhowtheuseofbestricefarmingpracticesaffectsthetotalyieldofricefarmers.Technicalefficiencyisachievedwhenitisnotpossibletoincreaseoutputwithoutincreasinginputs.Duetotechnicalinefficiencies,thereisahugegapbetweenactualandpotentialyieldsofricefarmersinsub−SaharanAfrica.Forinstance,thericeyieldofuplandfarmers,insub−SaharanAfrica,isestimatedat1t/hawhereastheyieldsatresearchstationsrangesbetween2.5to5t/ha.Thisyieldgapismainlyattributedtoinappropriatefarmingpracticesandlackoffarmersaccesstomoderninputsthatinfluenceefficiencyinfarmersfields.Asaresult,thisstudyassesseshowtheintroductionofbestagriculturalricefarmingpractices,throughagriculturaltrainingprograms,affectsthetechnicalefficiencyofsmallholderfarmersinTheGambia.Inthefirststage,weuseDataEnvelopmentAnalysis(DEA)techniquetoestimatetechnicalefficiencyscoresforeachsampledhouseholdandusedTobitregressiontoidentifyfactorsinfluencingtechnicalefficiency.Inthesecondstage,weemploypropensityscorematchingtoassessprogramimpactonparticipantsusingtechnicalefficiencyscoresasouroutcomeindicator.Theresultsoftheanalysisindicatethatagriculturaltrainingsignificantlyincreasestechnicalefficiencyofsmallholderricefarmersby10percent.Thistranslatestoriceyieldincreaseof260kg/ha,whichresultsinnetsocialandprivatebenefitsperannumofUS 43700 for 900 rice farming households and 30 extension agents, and US53perhousehold,respectively.OuranalysisofinvestmentonagriculturaltrainingyieldsaNetPresentValue(NPV)ofUS 195816, a Benefit Cost Ratio (BCR) of 5.3 and an Internal Rate of Return (IRR) of 99%. These results justify increased investment on agricultural training programs to boost rice production and productivity. Further analysis to identify determinants of technical efficiency show farmers contact with extension workers and a farmers association membership as significant factors influencing technical efficiency.
The significance of farmers contact with extension and association membership in determining technical efficiency indicates that extension contact and association membership could be important impact pathways to improve technical efficiency among smallholder farmers. The policy implication of these findings is to encourage rice farmers, through agricultural extension services, to be members of rice farmers associations and motivate them to meet regularly to exchange ideas and information about new developments within and outside their rice farming communities. Moreover, we define agricultural training as participation in at least one rice farmer training program. Since some training programs are likely to be more effective than others, defining participation as receipt of at least one training on rice cultivation practices is likely to underestimate the impact of highly effective training programs. Consequently, we recommend that future studies that intend to assess the impact of agricultural training on technical efficiency should identify specific training programs and assess their impact on technical efficiency separately.Die vorliegende Arbeit hat zum Ziel, den Einfluss von verbesserten Technologien und Programmen, die im Rahmen des Reisanbaus in Gambia eingeführt wurden um die lokale Reisproduktion zu steigern, zu evaluieren. Reis ist Hauptnahrungsmittel in Gambia. Der Reiskonsum pro Kopf wird auf 117kg pro Jahr geschätzt, und ist damit einer der höchsten in Subsahara-Afrika. Der landesweite jährliche Reiskonsum wird auf 195.811 Tonnen geschätzt, wovon 51.137 Tonnen im Inland produziert werden. Das gewaltige Defizit wird durch Importe zu geschätzten Kosten von jährlich 50 Millionen USausgeglichen.DieRegierungistdaherbestrebt,imBezugaufReisproduktionwirtschaftlicheUnabha¨ngigkeitzuerlangen.UmdiesesZielzuerreichen,habensichdieaktuellenBemu¨hungendaraufkonzentriert,ertragssteigerndelandwirtschaftlicheTechnologienundProgrammeeinzufu¨hren.SchwerpunktdervorliegendenArbeitistes,auszuwerten,wiesolcheTechnologienundProgrammedazubeitragen,wirtschaftlicheUnabha¨ngigkeitinderReisproduktioninGambiazuerreichen.UmdieAuswirkungenderTechnologienundProgrammeinderReisproduktionzuevaluieren,liegtderStudieeinlandesweiterDatensatzvonreisproduzierendenGemeinschaftenundHaushaltenvor,dieu¨bereinmehrstufigesStichprobenverfahrenausgewa¨hltwurden.DieDatenwurdenindenErntejahren2006−2010gesammelt,undwurdenverwendetumdreiverschiedeneForschungsfragenaufzustellen:(1)WiebeeinflusstderZugangzuSaatgutdiepotentielleEinfu¨hrungeinerverbessertenReisvariante?DerFallNewRiceforAfrica(NERICA)inGambia,(2)DieAuswirkungenderEinfu¨hrungvonNewRiceforAfrica(NERICA)aufErna¨hrungssicherheitundGesundheitingambischenHaushalten,und(3)DieAuswirkungenlandwirtschaftlicherWeiterbildungenkleinba¨uerlicherReisproduzentenzutechnischerEffizienzinGambia.DiesedreiForschungsfragenstellendiedreiHauptsa¨ulendervorliegendenDissertationdar.ZieldererstenForschungsfragewar,denBevo¨lkerungsanteilfestzustellen,derNERICASaatguteinsetzt,sowiedieFaktorendiezudessenEinsatzbeitragen.NERICAisteineertragreicheReissorte,welcheoffiziellimJahr2003inGambiaeingefu¨hrtwurde.DieEinfu¨hrungvonNERICAwareinVersuchderRegierung,dieReisproduktionunddieProduktivita¨tdesLandeszuerho¨hen.DievorliegendeStudiekonzentriertsichaufzweiprima¨reEinschra¨nkungenwelchedenEinsatzvonNERICASaatgutlimitieren:DasWissenderProduzentenu¨berdasVorhandenseinvonNERICASaatgut,sowiedenZugangdazu.UmdieseEinschra¨nkungenanzugehen,unddieunverzerrteAnwendungvonNERICASaatgutdurchdiegambischeBevo¨lkerungabzuscha¨tzen,wurdeeineWirkungsanalysedurchgefu¨hrt.DieErgebnissederAnalysezeigen,dassdieAnwendungsquotestattderinderStichprobevomJahr2010tatsa¨chlichbeobachtetenQuotevon66WeitereUntersuchungenzeigen,dassderEinsatzvonNERICASaatgutbei92DerKontaktderReisproduzentenzulandwirtschaftlichenBeratungsdienstenundeinerleichterterZugangzunichtmoneta¨renKreditenwurdenalsbedeutendeFaktorenfu¨rdenZugangzuunddenEinsatzvonNERICASaatgutsortenherausgestellt.DiePolitikempfehlungzudenErgebnissenlautet,denKontaktderReisproduzentenzulandwirtschaftlichenBeratungenzuverbessern,unddenZugangzunichtmoneta¨renKrediten,wiez.B.verbessertemSaatgut,fu¨ralleReisproduzentenzuerleichtern.Dieswu¨rdeho¨chstwahrscheinlichdasWissenumdieExistenzvonNERICASaatgutunddenZugangdazuverbessern,waswiederumdazubeitragenwu¨rde,dieAnwendungslu¨ckebeiNERICASaatgutindergambischenBevo¨lkerungbetra¨chtlichzuverkleinern.WennesBemu¨hungendahingehendgibt,diealleReisproduzentenu¨berdasVorhandenseinvonNERICASaatgutsorteninKenntniszusetzen,undu¨berdiesdasSaatgutfu¨rallezuga¨nglichgemachtwird,wirdesaußerdemfu¨rku¨nftigeForschungsvorhabennichtmehrbedeutsamsein,weiterhindieAnwendungsquotevonNERICASaatgutindergambischenReisproduzentenschaftzuerheben.UntersolchenUmsta¨ndenwa¨reessinnvoller,denEinsatzvonNERICAzubewerten,indemdieIntensita¨tinderTechnologienutzungunterdenAnwendernerhobenwird.Letztereswu¨rdeeindetaillierteresBildbezu¨glichderAttraktivita¨tderNERICATechnologiefu¨rdieZielgruppederReisproduzentenschaftergeben.DiezweiteForschungsfragezieltdaraufab,VerbesserungenhinsichtlichderErna¨hrungssicherheitindenHaushalten,sowieErgebnisindikatorenzugesundheitlichenAuswirkungenzuidentifizieren,diederAnwendungvonNERICASaatgutzugeschriebenwerdenko¨nnen.Hierfu¨rwurdenFoodConsumptionScores(FCS)undKrankheitstageproKopfderreisproduzierendenHaushaltsmitgliederalsErgebnisindikatorenfu¨rErna¨hrungssicherheitundGesundheitherangezogen.DadieEntscheidungzumEinsatzvonNERICASaatgutvondenReisproduzentengetroffenwird,wirdangenommen,dassdieseAuswahlentscheidungteilweiseaufnichtbeobachtbarenFaktorenbasiert,wiebeispielsweisedieEinstellungderReisproduzentenzuihrerArbeit.DaherwurdeeineInstrumentvariableangewendet,umkausaleEffektedesEinsatzesvonNERICASaatgutaufErna¨hrungssicherheitundGesundheitzuermitteln.DieErgebnissedieserAnalysezeigensignifikanteUnterschiedebeieinigensozioo¨konomischenunddemografischenSchlu¨sselmerkmalenzwischenNERICAAnwendernundNicht−Anwendern.DiesebeinhaltendieErfahrungbeimReisanbauinHochlagen,dasaußerlandwirtschaftlicheEinkommen,denKontaktzulandwirtschaftlichenBeratungenundZugangzuKrediten.SolcheVariablenko¨nnendieAuswirkungendesEinsatzesvonNERICASaatgutverzerren,wennsienichtinausgeglichenemUmfangbeidenBehandlungs−undKontrollgruppenvorkommen.WenneineGruppebeispielsweiseeinho¨heresaußerlandwirtschaftlichesEinkommenhat,ko¨nntenUnterschiedeinnerhalbderbeidenGruppeninErna¨hrungssicherheitundGesundheitsversorgungursa¨chlichvondieserVariablenstammenundsindnichtnotwendigerweisedemEinsatzvonNERICASaatgutzuzuschreiben.UmsolcheDifferenzenzuregulieren,undeinekausaleInterpretationderAuswirkungendesEinsatzesvonNERICASaatgutzuermo¨glichen,wirdderLocalAverageTreatmentEffect(LATE)kalkuliert.DieErgebnissedeutendaraufhin,dassderEinsatzvonNERICASaatgutdenLebensmittelkonsuminnerhalbeinesHaushaltssignifikantumdurchschnittlich14DieTatsache,dassdiepositivenAuswirkungendesEinsatzesvonNERICASaatgutaufdieErna¨hrungssicherheitfu¨rHaushaltemitZugangzuNaturalkreditenwiebeispielsweiseinFormvonverbessertemSaatgut,gro¨ßersind,machtesfu¨rdiePolitikerforderlich,dienotwendigenBemu¨hungenzuunternehmen,umNERICASaatgutvonGebietenmithoherProduktionsleistungzureisproduzierendenDo¨rfernmitniedrigemZugangaufnicht−moneta¨reKrediteumzuverteilen.DassdieAuswirkungendesEinsatzesvonNERICASaatgutaufErna¨hrungssicherheitbeiHaushaltenmitma¨nnlichemHaushaltsvorstandgro¨ßersind,weistnichtnotwendigerweisedaraufhindassderEinsatzvonNERICASaatgutkeinesignifikantenAuswirkungenaufdieErna¨hrungssicherheitvonFrauenaufindividuellerEbenehat.DieverwendetenDatenwurdenaufHaushaltsebenegesammelt,sodassesnichtmo¨glichwar,dieErna¨hrungssicherheitbeieinzelnenPersonenzuerfassen.Daherempfehlenwir,dasssichku¨nftigeStudien,welchedieAuswirkungendesEinsatzesvonNERICAaufdieErna¨hrungssicherheiterfassenwollen,DatenaufindividuellerEbenesammelnsollten,umeinengeschlechtsspezifischenVergleichzurErna¨hrungssicherheitbeiMa¨nnernundFrauenzuermo¨glichen.WeiterhingibtesBehauptungen,dassNERICASaatgutsortenimVergleichzutraditionellenundimportiertenReisvarianteneinenho¨herenProteingehaltundeineausgeglichenereKompositionvonAminosa¨urenha¨tten.Diesko¨nntebeiHaushaltendieNERICAeinsetzenzupositivenAuswirkungenimGesundheitsbereichfu¨hren.AllerdingshabendieErgebnisseunsererStudiekeinesignifikantenAuswirkungendesEinsatzesvonNERICAaufdieGesundheitergeben.Letzteresko¨nntederTatsachegeschuldetsein,dassdieInformationenallerHaushaltsmitgliederverwendetwurdenumdieKrankheitstageproKopfzuermitteln.DerzeitgibtesinGambiaeinenkostenlosenGesundheitsdienstfu¨rdiemeistenKurzzeit−ErkrankungenbeiKindern,woraussichdieinsignifikantenErgebnissedervorliegendenStudieergebenhabenko¨nnten.Daherempfehlenwir,dassku¨nftigeStudiendiesichmitdenAuswirkungendesNERICAEinsatzesaufdieGesundheitbefassen,sichauferwachsene,arbeitsfa¨higeHaushaltsmitgliederkonzentrierensollten,dadieseeinbessererErgebisindikatorseinko¨nnten.DiedritteForschungsfragezieltschließlichdaraufab,VerbesserungenindertechnischenEffizienzbeiKleinbauernimReisanbauzuermitteln,diedenlandwirtschaftlichenWeiterbildungsprogrammenfu¨rReisproduzentenzuzuschreibensind,welcheinGambiaeingefu¨hrtwurdenumdieReisproduktionundProduktivita¨tzusteigern.IndervorliegendenStudiewirdgemessen,wiedieAnwendungderbestenReisanbaumethodendenGesamtertragderReisproduzentenerho¨ht.AufgrundtechnischerIneffizienzenklaffteinegroßeLu¨ckezwischendemtatsa¨chlichenunddempotentiellmo¨glichenErtragderReisproduzenteninSubsaharaAfrika.DerReisertragderProduzentenimHochlandliegtetwabeieinerTonneproHektar,wa¨hrenddieErtra¨geanForschungsstandpunkten2,5bis5TonnenproHektarbetragen.DieseErtragslu¨ckewirdhauptsa¨chlichunangemessenenAnbaumethodenzugeschrieben,dieaufdenReisfeldernweitverbreitetsind.InfolgedessensolldievorliegendeStudieerfassen,wieeineEinfu¨hrungderbestenReisanbaumethodendurchlandwirtschaftlicheWeiterbildungsprogrammedietechnischeEffizienzdergambischenKleinbauernbeeinflusst.DerkausaleWirkungszusammenhangderlandwirtschaftlichenWeiterbildungmittechnischerEffizienzwirdinzweiPhasenbemessen.IndererstenPhasewirddieDataEnvelopmentAnalysis(DEA)verwendet,umtechnischeEffizienz−Wertefu¨rjedenbefragtenHaushaltzuermitteln,sowieeineTobit−Regressionsanalysedurchgefu¨hrt,umdieFaktorenzuermitteln,dieeinenEinflussaufdietechnischeEffizienzhaben.InderzweitenPhasewirddiePropensityScoreMatchingMethodeangewendet,umdieAuswirkungenvonWeiterbildungsprogrammenaufderenTeilnehmerzuerfassen,wobeitechnischeEffizienz−WertealsErgebnisindikatordienen.DieErgebnissederAnalysezeigen,dasslandwirtschaftlicheWeiterbildungendieFa¨higkeitderreisproduzierendenKleinbauern,diebestenAnbaumethodenanzuwenden,signifikantum10 für 900 reisproduzierende Haushalte und 30 Berater, bzw. 53 USproHaushalt.EineAnalysederInvestitionendieinlandwirtschaftlicheBeratunggeta¨tigtwerdenergibteinenKapitalwert(NPV)von195.815,8US, ein Kosten-Nutzen-Verhältnis von 5,3 und einen internen Zinssatz (IRR) von 99%. Diese Ergebnisse rechtf
Biotechnology is an important tool which can ensure the production of crop that will have longer shelf live, drought resistant, high saline tolerance, ability to withstand adverse conditions among others. The Gambia among the low-income West African countries, where agriculture is practiced by two-thirds of its citizens and couple with global population which is now around 7 billion predicted to rise to 9 billion by 2050, the Gambian government really needs to act fast and positively in welcoming genetically modified crops if it’s to be able to feed its population now roughly around 2 million people. Application of Biotechnology in crop and animal farming through genetic engineering has led to the development of crops with desirable characteristics such as crop varieties that cope better with drought and salinity, crops that more resistant to pest and diseases and crops that use nutrients more efficiently. This can help transform The Gambia into a country with a robust agriculture capable of not feeding the nation but also generating substantial foreign exchange. Through Agricultural biotechnology, this looming crisis can be averted eradicating malnutrition by ensuring food self-sufficiency through the production of resistant crops to pests and diseases, having longer shelf-lives, higher nutritional content and palatability, higher yields and early maturity period, tolerant to adverse weather and soil conditions. Achieving food sufficiency which is a direct consequence of a flourishing agricultural sector will facilitate a shift from other natural resources as a source of foreign exchange thus promoting economic diversity through agriculture
Human African trypanosomiasis (HAT) is a neglected tropical disease that is caused by flagellated parasites of the genus Trypanosoma. HAT imposes a significant socio-economic burden on many countries in sub-Saharan Africa and its control is hampered by several drawbacks ranging from the ineffectiveness of drugs, complex dosing regimens, drug resistance, and lack of a vaccine. Despite more than a century of research and investigations, the development of a vaccine to tackle HAT is still challenging due to the complex biology of the pathogens. Advancements in computational modeling coupled with the availability of an unprecedented amount of omics data from different organisms have allowed the design of new generation vaccines that offer better antigenicity and safety profile. One of such new generation approaches is a multi-epitope vaccine (MEV) designed from a collection of antigenic peptides. A MEV can stimulate both cellular and humoral immune responses as well as avoiding possible allergenic reactions. Herein, we take advantage of this approach to design a MEV from conserved hypothetical plasma membrane proteins of Trypanosoma brucei gambiense, the trypanosome subspecies that is responsible for the west and central African forms of HAT. The designed MEV is 402 amino acids long (41.5 kDa). It is predicted to be antigenic, non-toxic, to assume a stable 3D conformation, and to interact with a key immune receptor. In addition, immune simulation foresaw adequate immune stimulation by the putative antigen and a lasting memory. Therefore, the designed chimeric vaccine represents a potential candidate that could be used to target HAT
Background: The coronavirus disease (COVID-19) pandemic resulted in an unprecedent global response for the development of COVID-19 vaccines. However, as viral mutations continue to occur, potentially decreasing the efficacy of currently available vaccines, and inequity of vaccine access continues, identifying safe and effective drugs to minimise severity of COVID-19 disease remains a priority.
Methods: We designed an adaptive individually randomised single blinded non identical placebo-controlled trial to evaluate the safety and efficacy of repurposing licenced treatments for COVID-19 patients in an African setting. The trial has two cohorts: Cohort 1 recruits mild and moderate COVID-19 cases and their household contacts. Cases are actively followed up for 14 days, with a final visit at day 28. There are two co-primary endpoints: clinical progression to severe-pneumonia and persistence of the virus at day 14. The primary endpoint for household contacts is infection during a 14-day follow-up period. Cohort 2 recruits hospitalized patients with severe COVID-19 associated pneumonia followed up actively until discharge or death, and passively until day 90, with a final visit. The primary endpoint is clinical progression or death.
Conclusions: This randomised trial will contribute African-specific data to the global response to COVID-19. Besides the efficacy of drugs on clinical progression, the trial will provide information on the dynamics of intra-household transmission.
Trial registration: This study is registered with Clinical Trials.gov with registration number NCT04703608 and with Pan African clinical trials registry with registration number PACTR202101544570971
30.04.2021 tarihine kadar kullanımı yazar tarafından kısıtlanmıştır.YÖK Tez No: 652630İhtiyat güdüsüyle tasarruf, tüketicilerin geleceteki gelir belirsizlikler veya beklenmedik olaylar nedeniyle gelecek gelirlerinin düşmesine karşı önlem almak niyetiyle para veya varlık biriktirmesi olarak tanımlanmaktadır (Warneryd, 1999; Keynes, 1936). Bu tezin amacı Türk hanehalkının ihtiyat güdüsüyle tasarruf edip etmediğini araştırmaktır. Araştırmayı yürütmek için, 2011 ile 2017 yıllar arasındaki Türk Hanehalkı Bütçe Anketi veri setini kullanarak sentetik veya sanal panel veriyi oluşturmaktayım. Ayrıca, kohort analizini yaparak gelir artışı varyansı ile tasarruf ve toplam net varlık arasındaki ilişkiyi incelemekteyim. Böylece, gelir artışı varyansı, gelir riskini ölçen bir değişken olarak kullanarak en küçük kareler yöntemiyle gelir artışı varyansının tasarruf ve toplam net varlık üerindeki etkisini incelemekteyim. Bulgularıma göre, gelir artışı varyansının hem tasarruf hemde toplam net varlık üzerindeki etkisi pozitif olup Türk hanehalkının ihtiyat güdüsüyle tasarruf ettiğini kanıtlamaktadır.The precautionary saving motive is when consumers save money or accumulate more wealth to insure themselves against future income uncertainties or unforeseen events which may lead to any unexpected decrements in their future income (Warneryd, 1999; Keynes, 1936). This thesis aims to investigate the precautionary saving motive of Turkish households. I investigate this issue by constructing a pseudo panel data set from the Turkish Household Budget Survey data between 2011 and 2017. Then, I conduct a cohort-level analysis and explore the relationship between the variance of income growth and saving as well as total net-worth. So I use the variance of income growth as my measure of income risk and apply a pooled OLS regression to determine the impact of income growth variance on saving and total net-worth. The results show a positive impact of the variance of income growth on saving and total net-worth, thereby leading me to conclude that there's a precautionary saving motive among Turkish households
The Gambia, West Africa has only one operational television station. The Gambia Radio and Television Services (GRTS) serves as the sole television station in the country and is government owned. Although GRTS is a public government owned station, it does sell airtime for commercial use. The purpose of this thesis is to analyze the television program selection and scheduling strategies at GRTS in comparison to the needs of its viewing audience and potential advertisers.The goal of this research is not only to provide a current analysis of the programming department of GRTS in terms of scheduling and strategies, it is also to highlight the effects of those decisions on the audience as well as the current and potential advertisers utilizing the platform. To give a broader understanding of the inner workings of GRTS, a more in depth analysis will be utilized regarding other relevant departments within the institution. For this study, the methodologies used were interviews, surveys and field observations.M.S., Television Management -- Drexel University, 201
This study estimates the adoption gap of NERICA that exists in the population when access to seeds is a constraint. Treatment evaluation technique is applied to con-sistently estimate the potential NERICA adoption rate and its determinants using panel data from a stratified random sample of 515 rice farmers in The Gambia. The results show that the NERICA adoption rate could have been 76% instead of the observed 66% sample estimate in 2010 provided that every rice farmer had been aware of NERICA’s existence before the 2010 rice growing season. However, further investigation finds that if all the rice farmers had been aware of and had access to NERICA seeds, adoption would have been 92%. This reveals that if awareness had not been a constraint, 16% of farmers would have failed to adopt NERICA due to lack of access to seeds. Farmer contact with extension services and access to in-kind credit are significant determinants of access to and adoption of NERICA varieties
Fonio is an easy crop to grow because it grows well even on poor sandy soils, as well as in areas with low rainfall. The crop can withstand long dry spells during the production season which are becoming a common occurrence in the West African sub-region. In The Gambia, the common name for the crop is “Findi”. It is commonly grown in fields that were previously cultivated with groundnut. Fonio is one of the oldest cereal crops grown in the country; however, its cultivation has drastically declined to the extent that it is currently considered a minor crop in the country. Fonio is a very fast-growing crop and matures earlier than most cereals. Its ability to withstand dry spells and its high nutritive value makes it an ideal climate-smart crop. For this reason, there is renewed momentum in promoting the crop in the country. Despite these renewed efforts in its promotion, there still exists a huge gap in terms of information on improved production practices that could help uplift the existing low yields. Appropriate agronomic practices that can boost fonio productivity are not well documented at national level. To gather information on the input requirements and utilizations, adaptability and productivity of fonio in The Gambia, experiments were conducted in 2018 and 2019 with the aim of generating important production information that could guide efficient production and enhance productivity. Results obtained showed that fonio responded positively to application of fertilizer. Application of 100 kg ha -1 comprising half NPK (15-15-15) and half urea was sufficient to produce financially beneficial yields. Results also indicated that “Findiba”, which is a landrace may not be suitable for cultivation anymore due to its long growth period amidst the short and erratic nature of the rainfall. The Momo and the Momosato varieties which are of shorter durations and high-yielding are more suitable in the existing climatic conditions of the country