On Sterile neutrino explanation of LSND and MiniBooNE anomalies

We examine the compatibility between existing experimental data and a recently proposed explanation of the LSND and MiniBooNE anomalies, given in terms of a sterile neutrino $N$ whose decay is dominated by a radiative mode. We find that current experimental data on $\tau\rightarrow \mu\nu\nu\gamma$ decays are compatible with the sterile neutrino parameters required for the explanation of the anomalies, but $K\rightarrow \mu\nu\gamma$ shows a marginal tension with those parameters. We also propose experimental cuts on radiative $K$ decays that could test the sterile neutrino hypothesis better. Finally, we study the contribution of this sterile neutrino to $K\to\mu\nu e e$, and find that measurements of this process would provide powerful tests for the sterile neutrino explanation of the LSND and MiniBooNE anomalies, if the experimental cut on the invariant mass of the $e^{+}e^{-}$ pair could be reduced from its current value of 145 MeV to a value below 40 MeV.Comment: 6 pages, 2 figures, experimental cut taken into account, some conclusions change

Plantas medicinales usadas por los cogui en el río palomino, sierra nevada de santa marta (colombia)

Con el propósito de registrar conocimientos tradicionales sobre plantas medicinales entre los Cogui o Kággaba en la cuenca del río Palomino, Sierra Nevada de Santa Marta (Colombia), se evaluó el uso de la flora con la aplicación de una técnica etnobotánica cuantitativa. Mediante entrevistas a mamos o sacerdotes-jefes, durante recorridos en áreas silvestres, cultivadas y huertos caseros en diferentes zonas climáticas de la cuenca, se obtuvo información de 189 especies utilizadas, incluidas en 162 géneros y 77 familias, así como el modo de uso y la forma de preparación para el tratamiento de enfermedades comunes. Las familias Asteraceae y Leguminosae registraron el mayor número de especies útiles. La evaluación con el índice de importancia relativa (IR) permitió establecer que Ladenbergia moritziana (Rubiaceae), Stevia lucida (Asteraceae), Aniba sp. (Lauraceae), Erechtites hieracifolia (Asteraceae) y Carex sp. (Cyperaceae) son las especies con mayores valores de importancia. El 89 % de las plantas utilizadas es obtenido de espacios silvestres, lo que sugiere un conocimiento amplio de la diversidad vegetal local y el ejercicio de una práctica etnomédic

Heavy Sterile Neutrinos in Tau Decays and the MiniBooNE Anomaly

Current results of the MiniBooNE experiment show excess events that indicate neutrino oscillations, but only if one goes beyond the standard 3 family scenario. Recently a different explanation of the events has been given, not in terms of oscillations but by the production and decay of a massive sterile neutrino with large transition magnetic moment. We study the effect of such a sterile neutrino in the rare decays $\tau^- \rightarrow \mu^- \mu^+ \pi^- \nu$ and $\tau^{-}\rightarrow \mu^{-} \mu^{+} e^{-} \nu \nu$. We find that searches for these decays featuring displaced vertices between the $\mu^-$ and the other charged particles, constitute good tests for the existence of the sterile neutrino proposed to explain the MiniBooNE anomaly. These searches could be done with already existing experimental data.Comment: 4 pages, 1 figur

Genotyping of Trypanosoma cruzi in a hyper-endemic area of Colombia reveals an overlap among domestic and sylvatic cycles of Chagas disease

ABSTARCT: Chagas disease is a neglected illness caused by the Trypanosoma cruzi parasite, which widely affects American communities. This study attempted to identify T. cruzi genotypes circulating in four indigenous communities of the Sierra Nevada of Santa Marta, Colombia, to investigate parasite transmission dynamics in these communities. In addition, some epidemiological variables to determine the risk factors for infection with this parasite, such as the prevalence of T. cruzi infection, the triatomine species, and the domestic and sylvatic mammals that act as vectors and reservoirs of the parasite in the domestic, peridomestic and sylvatic cycles, were examined. METHODS:We developed a prospective study to identify the main risk factors associated with T. cruzi infection in the region. The T. cruzi prevalence was determined by ELISA, IFA and PCR. Triatomines species and both domestic and sylvatic mammals from all communities were captured and sampled. To analyze parasite transmission dynamics in these four communities, eight DNA parasite probes were generated from insect and reservoir samples, and a DNA blot analysis were carried out. RESULTS:Serological studies revealed 37% prevalence in the four communities, and Kasakumake was the most endemic region, containing approximately 70% seropositives. Moreover, the molecular diagnosis showed a high correlation between the serological data and the T. cruzi circulating in the patients' blood. A total of 464 triatomine insects were collected in domestic, peridomestic and sylvatic environments, and these insects belonged to five different species; Rhodnius prolixus and Triatoma dimidiata were the two more important species transmitting the parasite. After studying the eco-epidemiological factors in these four communities, the most important risk factors for infection with the parasite were determined. These risk factors are a high infection rate of people and domestic animals, the construction materials of the houses, the presence of infected triatomines inside the human dwellings, the proximity between houses and a sylvatic environment with several triatomine species and wild animals. Finally, the molecular characterization of T. cruzi showed the presence of three haplotypes and complex T. cruzi mixed infections in all reservoirs. CONCLUSIONS:Active transmission of T. cruzi is present in four indigenous communities of the Sierra Nevada de Santa Marta with overlap between the domestic and the sylvatic transmission cycles of Chagas disease

Nuevos hallazgos de Flebotomíneos (Diptera: Psychodidae) en la Sierra Nevada de Santa Marta, Colombia

Los insectos relacionados con la transmisión de los patógenos causantes de las leishmaniasis han sido poco estudiados en la Sierra Nevada de Santa Marta, Colombia, incluido el departamento de Magdalena, donde a la fecha están registradas trece especies del género Lutzomyia. En la presente nota se informa el hallazgo de tres especies y un subgénero adicionales en la región. Se recolectaron 885 flebotomíneos en Seywiaka y las veredas Las Tinajas y Calabazo, estribaciones de la Sierra Nevada de Santa Marta (117-130 m s.n.m.). El 84 % de los ejemplares se obtuvieron con trampa CDC, el 11 % con trampa Shannon y el 5 % fueron capturados, en reposo, con un dispositivo eléctrico de succión. Se identificaron nueve especies, Lu. gomezi, Lu. panamensis, Lu. trinidadensis, Lu. carpenteri, Lu. evansi, Lu. dysponeta, Lu. dubitans, Lu. shannoni, y Lu. micropyga, la más abundante fue Lu. gomezi (69 %), seguida por Lu. panamensis (14 %). También se recolectaron ejemplares de la serie Lu. osornoi del subgénero Helcocyrtomyia. Entre el material hallado sobresalen Lu. carpenteri, Lu. dubitans y Lu. dysponeta como primeros registros para el departamento del Magdalena, además de Lu. (Helcocyrtomyia) sp., que representa el primer informe del subgénero en el Caribe colombiano.Phlebotomine sand flies, vectors of leishmaniasis, have not been well studied in the Sierra Nevada de Santa Marta, and likewise, are not well known in other regions of the Department of Magdalena, Colombia. To date only thirteen species of Lutzomyia have been recorded as occurring in the Department. The present note adds three species and includes an additional subgenus. Collections were made in the lower foothills of the Sierra Nevada de Santa Marta at elevations ranging from 117–130 m in the communities of Seywiaka, Las Tinajas and Calabazo. Eighty-four percent of the 885 phlebotomines sand flies collected were obtained from CDC light traps, 11 % from Shannon trap and 5 % from typical resting sites using an electric aspirator. The following nine species were identified from the collections: Lutzomyia gomezi, Lu. panamensis, Lu. trinidadensis, Lu. carpenteri, Lu. evansi, Lu. dysponeta, Lu. dubitans, Lu. shannoni, and Lu. micropyga. The most abundant species were Lu. gomezi and Lu. panamensis, which, respectively, accounted for 69 % and 14 % of the specimens. Of the nine species, Lu. carpenteri, Lu. dubitans and Lu. dysponeta represent new records for the Department of Magdalena. Also, a few female specimens were encountered of a species belonging to the Lu. osornoi series of the subgenus Helcocyrtomyia, which represents the first record of this subgenus in the Caribbean region of Colombia

Reconstructing Native American population history

The peopling of the Americas has been the subject of extensive genetic, archaeological and linguistic research; however, central questions remain unresolved. One contentious issue is whether the settlement occurred by means of a single migration or multiple streams of migration from Siberia. The pattern of dispersals within the Americas is also poorly understood. To address these questions at a higher resolution than was previously possible, we assembled data from 52 Native American and 17 Siberian groups genotyped at 364,470 single nucleotide polymorphisms. Here we show that Native Americans descend from at least three streams of Asian gene flow. Most descend entirely from a single ancestral population that we call First American. However, speakers of Eskimog-Aleut languages from the Arctic inherit almost half their ancestry from a second stream of Asian gene flow, and the Na-Dene-speaking Chipewyan from Canada inherit roughly one-tenth of their ancestry from a third stream. We show that the initial peopling followed a southward expansion facilitated by the coast, with sequential population splits and little gene flow after divergence, especially in South America. A major exception is in Chibchan speakers on both sides of the Panama isthmus, who have ancestry from both North and South America. © 2012 Macmillan Publishers Limited. All rights reserved.Fil: Reich, David. Harvard Medical School; Estados Unidos. Massachusetts Institute of Technology; Estados UnidosFil: Patterson, Nick. Massachusetts Institute of Technology; Estados UnidosFil: Campbell, Desmond. Colegio Universitario de Londres; Reino Unido. The University Of Hong Kong; Hong KongFil: Tandon, Arti. Harvard Medical School; Estados Unidos. Massachusetts Institute of Technology; Estados UnidosFil: Mazieres, Stéphane. Colegio Universitario de Londres; Reino UnidoFil: Ray, Nicolas. Universidad de Ginebra; SuizaFil: Parra, Maria V.. Colegio Universitario de Londres; Reino Unido. Universidad de Antioquia; ColombiaFil: Rojas, Winston. Colegio Universitario de Londres; Reino Unido. Universidad de Antioquia; ColombiaFil: Duque, Constanza. Universidad de Antioquia; Colombia. Colegio Universitario de Londres; Reino UnidoFil: Mesa, Natalia. Universidad de Antioquia; Colombia. Colegio Universitario de Londres; Reino UnidoFil: García, Luis F.. Universidad de Antioquia; ColombiaFil: Triana, Omar. Universidad de Antioquia; ColombiaFil: Blair, Silvia. Universidad de Antioquia; ColombiaFil: Maestre, Amanda. Universidad de Antioquia; ColombiaFil: Dib, Juan C.. Fundación Salud Para El Tró Pico; ColombiaFil: Bravi, Claudio Marcelo. Colegio Universitario de Londres; Reino Unido. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; ArgentinaFil: Bailliet, Graciela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; ArgentinaFil: Corach, Daniel. Universidad de Buenos Aires; ArgentinaFil: Hünemeier, Tábita. Colegio Universitario de Londres; Reino Unido. Universidade Federal do Rio Grande do Sul; BrasilFil: Bortolini, Maria Cátira. Universidade Federal do Rio Grande do Sul; BrasilFil: Salzano, Francisco M.. Universidade Federal do Rio Grande do Sul; BrasilFil: Petzl Erler, María Luiza. Universidade Federal do Paraná; BrasilFil: Acuña Alonzo, Victor. National Institute Of Anthropology And History; MéxicoFil: Aguilar Salinas, Carlos. Instituto Nacional de la Nutrición Salvador Zubiran; MéxicoFil: Canizales-Quinteros, Samuel. Universidad Nacional Autónoma de México; MéxicoFil: Tusié Luna, Teresa. Universidad Nacional Autónoma de México; MéxicoFil: Riba, Laura. Universidad Nacional Autónoma de México; MéxicoFil: Rodríguez Cruz, Maricela. Umae Hospital de Pediatría Centro Medico Nacional Siglo Xxi; MéxicoFil: Lopez Alarcón, Mardia. Umae Hospital de Pediatría Centro Medico Nacional Siglo Xxi; MéxicoFil: Coral Vazquez, Ramón. Instituto Politécnico Nacional; Méxic

La familia y los amigos como riesgo de consumo de alcohol en adolescentes / Family and friends as risk for alcohol consumption in adolescents

La adolescencia es una etapa de experimentación de conductas oposicionistas y/o desafiantes. Los problemas de comunicación, el aislamiento emocional y la carencia de afecto familiar se transforman en factores de riesgo para el consumo de alcohol. El objetivo de este trabajo es identificar los factores de riesgo para el consumo de alcohol en los estudiantes de primero, segundo y tercer año de bachillerato de colegios de Guayaquil. A una muestra de 636 adolescentes de los tres años de bachillerato se le aplicó una encuesta diseñada para el estudio, aprobada por un comité de Bioética (COBI) que incluyó el AUDIT y el APGAR familiar, autoadministrable. Se utilizó estadística descriptiva y asociación de variables con un nivel de confianza del 95% y una p significativa <0,05. Se empleó el programa SPSS versión 21 y la prueba Chi cuadrado. Los resultados indican que el 52% de los adolescentes se expuso al alcohol alguna vez en su vida y el 65% presentó disfunción familiar de algún grado, siendo esto más evidente en el grupo donde no había satisfacción con la forma en que el núcleo familiar respondía a sus necesidades de comunicación y afecto. En este estudio se pretende desarrollar estrategias que fomenten la toma de decisiones saludables y mejoren el bienestar emocional de adolescentes. Abstract Adolescence is a stage of experimentation of oppositional and/or defiant behaviors. Communication problems, emotional isolation and lack of family affection become risk factors for consumption of alcohol. The objective of this research is to identify the risk factors for alcohol consumption in students of first, second and third year of high schools in Guayaquil. A survey approved by a Bioethics committee was applied to 636 adolescents from first, second and third year of high school that included the AUDIT and family APGAR, which is self-administered. Descriptive statistics and variables association were used with a confidence level of 95% and a significant p < 0,05. It was executed the software SPSS version 21 and the Chi Square test was applied. The results show that 52% of teens were exposed to alcohol consumption some time in their life and also 65% had some degree of family dysfunction, being this more evident in the group where there is no satisfaction with the way the household responded to their communication and affection needs. This research attempts to develop strategies to encourage healthy decision-making to and improve the emotional wellbeing of teenagers.