98 research outputs found
Chemical and biological recovery of soils contaminated with antimony using eco-friendly materials
Antimony (Sb), a non-essential plant element, can be present in soils and waters in very high concentrations often due to a variety of anthropogenic activities. Though antimony is classified as a pollutant of priority interest, very little is known about its environmental behaviour and soil speciation.
In recent years, different sorbents for the in-situ remediation of metalloid-polluted soils were proposed and tested with variable success. In a search for alternative, low-cost and environmental friendly Sb sorbents, drinking water treatment residuals (WTRs), the waste material resulting from the treatment of surface or ground water, and municipal solid waste compost (MSWC) were identified as potential good candidates.
In this PhD thesis we showed that the Sb mobility, and its impact on the microbial and biochemical features of two soils artificially contaminated, were highly influenced by selected soil properties such as pH and organic matter content. Both WTRs and MSWC were able to act as effective Sb(V)-immobilizing agents in aqueous solutions especially at acidic pH (i.e. 4.5). Moreover, when added to a contaminated mine soil, the combination of both sorbents significantly reduced the mobility of antimony, alleviated its impact on soil microbiota and promoted a recovery of soil biochemical functioning. Plant growth (Helichrysum italicum L.) in the amended soil was finally enhanced while the Sb uptake was definitively reduced
Prone positioning and convalescent plasma therapy in a critically ill pregnant woman with COVID-19
Prone positioning is feasible in pregnancy and may have contributed to the positive outcome in this case. Doctors should not be reluctant to move a patient to a prone position just because they are pregnant
ACL surgery: reasons for failure and management
Abstract
Despite the general success of anterior cruciate ligament reconstructions (ACL-R), there are still studies reporting a high failure rate. Orthopedic surgeons are therefore increasingly confronted with the treatment of ACL retears, which are often accompanied by other lesions, such as meniscus tears and cartilage damage and which, if overlooked, can lead to poor postoperative clinical outcomes. The literature shows a wide variety of causes for ACL-R failure. Main causes are further trauma and possible technical errors during surgery, among which the position of the femoral tunnel is thought to be one of the most important. A successful postoperative outcome after ACL-revision surgery requires good preoperative planning, including a thorough evaluation of patient's medical history, e.g. instability during daily or sports activity, increased general joint laxity, and hints for a low-grade infection. A careful clinical examination should be performed. Additionally, comprehensive imaging is necessary. Besides a magnetic resonance imaging, a CT scan is helpful to determine location of tunnel apertures and to analyze for tunnel enlargement. A lateral knee radiograph is helpful to determine the tibial slope. The range of surgical options for the treatment of ACL-R failure is broad today. Orthopedic surgeons and experts in Sports Medicine must deal with various possible associated injuries of the knee or unfavorable anatomical conditions for ACL-R. The aim of this review was to highlight predictors and reasons of failures of ACL-R as well as describe diagnostic procedures to individualize treatment strategies for improved outcome after revision ACL-R.
Keywords: ACL reconstruction; ACL revision; ACL revision management; causes of graft failure
Attentional capture by a perceptually salient non-target facilitates target processing through inhibition and rapid rejection
Perceptually salient distractors typically interfere with target processing in visual search situations. Here we demonstrate that a perceptually salient distractor that captures attention can nevertheless facilitate task performance if the observer knows that it cannot be the target. Eye-position data indicate that facilitation is achieved by two strategies: inhibition when the first saccade was directed to the target, and rapid rejection when the first saccade was captured by the salient distractor. Both mechanisms relied on the distractor being perceptually salient and not just perceptually different. The results demonstrate how bottom-up attentional capture can play a critical role in constraining top-down attentional selection at multiple stages of processing throughout a single trial
Attentional capture by a perceptually salient non-target facilitates target processing through inhibition and rapid rejection
Perceptually salient distractors typically interfere with target processing in visual search situations. Here we demonstrate that a perceptually salient distractor that captures attention can nevertheless facilitate task performance if the observer knows that it cannot be the target. Eye-position data indicate that facilitation is achieved by two strategies: inhibition when the first saccade was directed to the target, and rapid rejection when the first saccade was captured by the salient distractor. Both mechanisms relied on the distractor being perceptually salient and not just perceptually different. The results demonstrate how bottom-up attentional capture can play a critical role in constraining top-down attentional selection at multiple stages of processing throughout a single trial
Four-Year Environmental Surveillance Program of Legionella spp. in One of Palermo’s Largest Hospitals
Legionella is a ubiquitous bacterium that lives in freshwater environments and colonizes
human-made water systems. Legionella pneumophila is the most virulent species, and risk factors
for Legionnaires’ disease include increasing age, smoking, chronic diseases, and immunodeficiency.
For this reason, it is very important to assess and monitor hospital water systems in order to prevent
legionellosis. We have monitored a large hospital in Palermo for four years. To determine the presence
of microorganisms, according to national guidelines, we used the culture method, which is considered
the gold standard for Legionella detection. Sampling was divided into five macro-areas, and a total of
251 samples were collected during the period of investigation, 49% of which were Legionella spp.-
positive and 51% were Legionella spp.-negative. Positive samples with L. pneumophila. sgr 2-15 were
most frequent in the Underground (55.6%, p = 0.0184), Medicine (42.9%, p = 0.0184) and Other (63.2%,
p = 0.002) areas; while positive samples for L. pneumophila sgr 1 were less frequent in the Underground
(0.0%, p = 0.0184) and Surgery areas (4.5%, p = 0.033), and for Legionella anisa, were less frequent
in the Medicine (4.1%, p = 0.021), Oncohematology (0.0%, p = 0.0282), and Other (0.0%, p = 0.016)
areas. Finally, no significant differences were observed among the areas for each isolate considered.
The surveillance carried out in these years demonstrates the importance of monitoring, which allows
us to analyze the conditions of hospital facilities and, therefore, prevent Legionella spp. infections
Potential Activity of Albino Grifola frondosa Mushroom Extract against Biofilm of Meticillin-Resistant Staphylococcus aureus
Mushroom extracts are a rich source of natural compounds with antimicrobial properties, which are able to prevent, to some extent, the growth of foodborne pathogens. The aim of this study was to investigate the potential of extracts from albino Grifola frondosa (GF), commonly known as maitake, to inhibit the growth of some bacteria and the biofilm production by Staphylococcus aureus.
We obtained not only a significant reduction of OD score between biofilm and biofilm plus albino G. frondosa extract group, but also a reduction of category of biofilm. In addition, we observed a significant presence of isolates with strong category for the biofilm group and a significant presence of isolates with absent category for the biofilm plus albino G. frondosa extract group. These results
confirm that the use of albino G. frondosa extract reduces in significant way the presence of biofilm. Our results suggest and confirm that albino G. frondosa extracts could be employed as functional food and could be used as a natural additive for food process control and food safety
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Functional connectivity between prefrontal and parietal cortex drives visuospatial attention shifts
It is well established that the frontal eye-fields (FEF) in the dorsal attention network (DAN) guide top-down selective attention. In addition, converging evidence implies a causal role for the FEF in attention shifting, which is also known to recruit the ventral attention network (VAN) and fronto-striatal regions. To investigatethe causal influence of the FEF as (part of) a central hub between these networks, we applied thetaburst transcranial magnetic stimulation (TBS) off-line, combined with functional magnetic resonance (fMRI) during a cued visuo-spatial attention shifting paradigm.
We found that TBS over the right FEF impaired performance on a visual discrimination task in both hemifields following attention shifts, while only left hemifield performance was affected when participants were
cued to maintain the focus of attention. These effects recovered ca. 20 min post stimulation. Furthermore, particularly following attention shifts, TBS suppressed the neural signal in bilateral FEF, right inferior and superior parietal lobule (IPL/SPL) and bilateral supramarginal gyri (SMG). Immediately post stimulation, functional connectivity was impaired between right FEF and right SMG as well as right putamen. Importantly,
the extent of decreased connectivity between right FEF and right SMG correlated with behavioural impairment
following attention shifts.
The main finding of this study demonstrates that influences from right FEF on SMG in the ventral attention network causally underly attention shifts, presumably by enabling disengagement from the current focus of attention
Environmental potential assessment of MSWI bottom ash-based alkali-activated binders
Alkali-activated binders (AABs) stand out as a sustainable alternative to ordinary Portland cement (OPC) as they can be formulated using by-products or waste as raw materials. However, the presence of hazardous compounds in residues can lead to an increase in AABs' toxicity due to the highly alkaline media. Therefore, it is extremely important to evaluate their environmental risks to validate their use as building materials. This study environmentally assessed AABs prepared with two different fractions (0-30 mm and 8-30 mm) of weathered bottom ash (AA-WBA) from WtE plants. The potential leachate toxicity of AA-WBA was assessed using granular and monolithic leaching tests that simulated end-of-life and service life scenarios, respectively. Furthermore, an acute toxicity test with crustacean Daphnia magna as model organisms was conducted to determine the relationship between the leachate metal(loid) concentrations and the ecotoxicity of AA-WBA. The results showed higher metal(loid) concentrations in AA-WBA specimens prepared with the 0-30 mm fraction of WBA. The service life scenario revealed multiple metal(loid)-release mechanisms. The 48 h EC50 value (close to 10%; moderate toxicity) indicated that the use of the coarse fraction of WBA increased the immobilisation of the metal(loid)s. Finally, the correlation between the concentrations of some of the metal(loid)s and toxicity was demonstrated.The work is funded by the Spanish Government (BIA2017–83912- C2–1-R). The authors would like to thank the Catalan Government for the quality accreditation given to their research groups DIOPMA (2017 SGR 118), to SIRUSA and VECSA for supplying the MSWI Bottom Ash, and Befesa Company for supplying the PAVAL. Mr Alex Maldonado-Alameda is grateful to the Government of Catalonia for his research Grant (FI-DGR 2017). Dr Jessica Giro-Paloma is a Serra HĂşnter Fellow. Dr Araceli RodrĂguez-Romero is supported by the Spanish grant Juan de la Cierva IncorporaciĂłn referenced as IJC2018–037545-I
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