488 research outputs found
Anti-bias pedagogy and the progressive legacy
This study uses qualitative data to investigate factors that support or hinder progressive teachers and school leaders in the implementation of anti-bias pedagogy in a variety of New York City elementary school
Guggenheim for All: Museum Education for Students on the Spectrum
The aim of this paper is to articulate the strengths of Guggenheim For All (GFA) as a place-based learning experience and the ways it can benefit students on the autism spectrum. I review educator practices in light of both Universal Design for Learning principles and best practices for teaching students with autism spectrum disorders (ASDs) and draw on anecdotal data from teachers that support a view of GFA as place-based learning
LA CONFISCA DI PREVENZIONE EX ART. 24 D. LGS. 6 SETTEMBRE 2011 N. 159. LA 'SFIDA' DEL PRINCIPIO DI PROPORZIONE
Il lavoro concerne il tema del contrasto patrimoniale alla criminalità organizzata e la confisca di prevenzione ante delictum (art. 24, d.lgs. n. 159/2011). Lo spregiudicato ricorso a questo strumento ha creato una confusione tra i piani della prevenzione (ante delictum) e della repressione (post delictum) della criminalità. Si nota, inoltre, la tendenza della confisca a sconfinare verso settori d’intervento della giustizia penale differenti da quelli per i quali è espressamente prevista.
La Parte prima della tesi è dedicata alla ricostruzione delle origini storiche delle misure di prevenzione patrimoniali, nonché ai presupposti e alle finalità di sequestro e confisca. La Parte seconda affronta il problema della natura giuridica della confisca. Alla dottrina che si è espressa per la sostanziale natura sanzionatoria della misura (formalmente) di “prevenzione”, si oppone la giurisprudenza che la estromette dalla materia penale e dalle garanzie (costituzionali e convenzionali). La Parte terza è dedicata alla ‘sfida’ del principio di proporzione: la verifica della ragionevolezza della confisca secondo il modello del giudizio trilaterale.
Nelle conclusioni si espongono delle considerazioni sui rapporti tra prevenzione ante delictum e principio di sussidiarietà, nell’ottica di una valorizzazione dell’idea di gradualità e di promozione dell’uguaglianza tra cittadini.The work concerns the contrast against organized crime and the preventive confiscation (art. 24, d.lgs. n. 159/2011). The use of confiscation has created a confusion between the plans of crime prevention (ante delictum) and crime repression (post delictum).
The first part of the thesis concerns: reconstruction of the historical origins of the preventive system; conditions and purposes of seizure and confiscation. The second part deals with the problem of the legal nature of confiscation. The doctrine has been expressed for substantial punitive measure; jurisprudence excludes confiscation from criminal law and its guarantees. The third part concerns the 'challenge' of the principle of proportionality: the verification of the reasonableness of confiscatione.
The conclusions expose the considerations on the relationship between prevention ante delictum and the principle of subsidiarity, to valorize the idea of gradually and of equality between citizens
PEIS stol: autonomni robotski stol za kućanstva
There are two main trends in the area of home and service robotics. The classical one aims at the development of a single skilled servant robot, able to perform complex tasks in a passive environment. The second, more recent trend aims at the achievement of complex tasks through the cooperation of a network of simpler robotic devices pervasively embedded in the domestic environment. This paper contributes to the latter trend by describing the PEIS Table, an autonomous robotic table that can be embedded in a smart environment. The robotic table can operate alone, performing simple point-to-point navigation, or it can collaborate with other devices in the environment to perform more complex tasks. Collaboration follows the PEIS Ecology model. The hardware and software design of the PEIS Table are guided by a set of requirements for robotic domestic furniture that differ, to some extent, from the requirements usually considered for service robots.U uslužnoj robotici i robotici za kućanstva postoje dva glavna trenda. Klasičan pristup teži razvoju jednog složenog uslužnog robota koji je sposoban izvršavati složene zadatke u pasivnom okruženju. Dok drugi, nešto noviji pristup, teži rješavanju složenih zadataka kroz suradnju umreženih nešto jednostavnijih robota prožetih kroz cijelo kućanstvo. Ovaj članak svoj doprinos daje drugom pristupu opisujući PEIS stol, autonomni robotski stol koji se može postaviti u inteligentnom okruženju. Robotski stol može djelovati samostalno, navigirajući od točke do točke ili može surađivati s ostalim uređajima u okruženju radi izvršavanja složenijih zadataka. Ta suradnja prati PEIS ekološki model. Dizajn sklopovlja i programske podrške PEIS stola prati zahtjeve za robotsko pokućstvo koji se donekle razlikuju od zahtjeva koji se inače postavljaju za
uslužne robote
Cátedra de Geoquímica: innovar en los trabajos prácticos
Este documento plantea la elaboración de un proyecto de intervención orientado a modificar la metodología de los trabajos prácticos de la asignatura Geoquímica. La materia es de carácter obligatorio del segundo año de las Licenciaturas en Geoquímica y en Geología de la Facultad de Ciencias Naturales y Museo. Se propone como innovación introducir en las clases prácticas una actividad especial con la intención de integrar varios trabajos prácticos previos relacionados a partir del trabajo con un ejemplo real. Esta propuesta supone una innovación en la metodología de enseñanza que implica articular e integrar los contenidos prácticos, a modo de hilo conector entre problemas que previamente se presentaban como inconexos. La práctica que se propone desarrollar en el aula busca promover un aprendizaje grupal, donde el docente acompaña el proceso para resolver la actividad especial de forma colectiva.Facultad de Ciencias Naturales y Muse
Insights into induction of the immune response by the hepatitis B vaccine
After more than four decades of hepatitis B virus (HBV) vaccine implementation, its safety and efficacy in preventing HBV infection have been proven and several milestones have been achieved. Most countries have included HBV immunization schedules in their health policies and progress has been made regarding universalization of the first HBV vaccine dose at birth. All of these actions have significantly contributed to reducing both the incidence of HBV infection and its related complications. However, there are still many drawbacks to overcome. The main concerns are the deficient coverage rate of the dose at birth and the large adult population that has not been reached timely by universal immunization. Additionally, the current most widely used second-generation vaccines do not induce protective immunity in 5% to 10% of the population, particularly in people over 40-years-old, obese (body mass index > 25 kg/m2), heavy smokers, and patients undergoing dialysis or infection with human immunodeficiency virus. Recently developed and approved novel vaccine formulations using more potent adjuvants or multiple antigens have shown better performance, particularly in difficult settings. These advances re-launch the expectations of achieving the World Health Organization’s objective of completing hepatitis control by 2030.Fil: Di Lello, Federico Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología. Cátedra de Virología; ArgentinaFil: Martínez, Alfredo Pedro. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínicas "Norberto Quirno". CEMIC-CONICET; ArgentinaFil: Flichman, Diego Martin. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas en Retrovirus y Sida. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas en Retrovirus y Sida; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología. Cátedra de Virología; Argentin
PEIS stol: autonomni robotski stol za kućanstva
There are two main trends in the area of home and service robotics. The classical one aims at the development of a single skilled servant robot, able to perform complex tasks in a passive environment. The second, more recent trend aims at the achievement of complex tasks through the cooperation of a network of simpler robotic devices pervasively embedded in the domestic environment. This paper contributes to the latter trend by describing the PEIS Table, an autonomous robotic table that can be embedded in a smart environment. The robotic table can operate alone, performing simple point-to-point navigation, or it can collaborate with other devices in the environment to perform more complex tasks. Collaboration follows the PEIS Ecology model. The hardware and software design of the PEIS Table are guided by a set of requirements for robotic domestic furniture that differ, to some extent, from the requirements usually considered for service robots.U uslužnoj robotici i robotici za kućanstva postoje dva glavna trenda. Klasičan pristup teži razvoju jednog složenog uslužnog robota koji je sposoban izvršavati složene zadatke u pasivnom okruženju. Dok drugi, nešto noviji pristup, teži rješavanju složenih zadataka kroz suradnju umreženih nešto jednostavnijih robota prožetih kroz cijelo kućanstvo. Ovaj članak svoj doprinos daje drugom pristupu opisujući PEIS stol, autonomni robotski stol koji se može postaviti u inteligentnom okruženju. Robotski stol može djelovati samostalno, navigirajući od točke do točke ili može surađivati s ostalim uređajima u okruženju radi izvršavanja složenijih zadataka. Ta suradnja prati PEIS ekološki model. Dizajn sklopovlja i programske podrške PEIS stola prati zahtjeve za robotsko pokućstvo koji se donekle razlikuju od zahtjeva koji se inače postavljaju za
uslužne robote
Inter and intrapatient evolution of hepatitis C virus
Hepatitis C virus (HCV) has a short replication time, high mutation rates and large population sizes, all of which make it an excellent experimental model for evolution studies, because evolution can be visualized in real-time. In this review, we discuss the implications to study HCV evolution at the interpatient and intrapatient levels of infection. The HCV interpatient dynamics is relatively slow, because the generation time is generally long. Then, at population level, the HCV diversity originated by the high mutation and replication rates is modulated by the bottleneck at transmission. Thus, when the virus is transmitted to other hosts, viral diversity is reduced as a result of the founder effect. On the other hand, during intrapatient infection, HCV evolves rapidly, resulting in quasispecies. Accumulated evidence suggests that this quasispecies composition of the HCV population within the same individual may allow the virus to evade the immune response or escape treatment, leading to chronic infection. Thus, a better understanding of the complexities underlying the molecular evolution of HCV in natural populations is needed before accurate predictions of viral evolution can be made. In summary, HCV evolves both within and among patients. Consequently, HCV evolution should be studied at both levels in order to better understand the natural history of the virus and its potential implications in epidemiology, outcome of infection and progression of liver disease.Fil: Di Lello, Federico Alejandro. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología. Cátedra de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Culasso, Andrés Carlos Alberto. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología. Cátedra de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Campos, Rodolfo Hector. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología. Cátedra de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin
Hepatitis C virus treatment failure: Clinical utility for testing resistance-associated substitutions
The hepatitis C virus has a high mutation capacity that leads to the emergence of resistance-associated substitutions (RAS). However, the consequence of resistance selection during new direct-acting antiviral drug (DAA) treatment is not necessarily the therapeutic failure. In fact, DAA treatment has shown a high rate (> 95%) of sustained virological response even when high baseline RAS prevalence has been reported. In the context of RAS emergence and high rates of sustained viral response, the clinical relevance of variants harboring RAS is still controversial. Therefore, in order to summarize the data available in international guidelines, we have reviewed the clinical utility of testing RAS in the era of new pangenotypic DAA drugs.Fil: Ridruejo, Ezequiel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínicas "Norberto Quirno". CEMIC-CONICET; ArgentinaFil: Pereson, Matías Javier. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Investigaciones en Bacteriología y Virología Molecular; ArgentinaFil: Flichman, Diego Martin. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas en Retrovirus y Sida. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas en Retrovirus y Sida; ArgentinaFil: Di Lello, Federico Alejandro. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Investigaciones en Bacteriología y Virología Molecular; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin
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