Reimplantation: clinical Implications and outcome of dry storage of avulsed teeth

Reimplantation refers to the insertion and temporary fixation of completely or partially avulsed teeth that have resulted from traumatic injury. Reimplantation of an avulsed tooth depends on certain clinical conditions like phy- siological status of periodontal ligament (PDL), the stage of root development and the length of extra oral time. Depending on the patient’s age, retention of the permanent incisor can maintain the aesthetic appearance, occlusal function and alveolar ridge height. Though the risk of progressive replacement resorption and subsequent tooth loss is high after a long dry storage, reimplantation makes a provision for an aesthetically acceptable permanent prosthesis at a later age. This article presents management of two cases with avulsed permanent incisors that were stored in dry conditions for seven hours and three days respectivel

Prevalent Dental Myths and Practices in Indian Population- A Systematic Review

Objectives: The present systematic review was conducted to assess knowledge and awareness on prevalent dental myths related to infant teething, pregnancy and cleft lip and palate and various oral health habits in Indian population. Method: Electronic and manual database was searched vigorously between period of January 1994 to January 2017 using PUBMED and GOOGLE SCHOLAR search engines to include relevant studies from peer-reviewed journals which have been conducted in India.Results: A total of 24 scientific questionnaire studies conducted in various states of India were included. 16 out of 24 studies (66.67%) dealt with various dental myths and practices prevalent among rural Indian population whereas only 1 study included both urban and rural populations. Region wise maximum studies were conducted in Southern region [8 studies (33.3%)] followed by 7 studies (29.16%) in Northern, 6 studies (25%) in Western and 1-1 study (4.16% each) in Eastern and Central India respectively. Conclusion: The results indicate that the knowledge and awareness levels about dental myths and oral practices in both rural and urban population in various regions of India is inadequate. It is necessary for dental practitioners to educate masses for better dental health

Diastema-The Treatment Dilemma

Spacing between adjacent teeth is known as Diastema, many of the patients seek closure of diastema for aesthetic reasons. Diastema less than 2 mm close spontaneously ,if they do not do so then they should not be straightaway corrected rather a thorough clinical and radiographic examination should done to  determine the underlying cause and to rule out anomalies, such as the presence of any supernumerary  tooth or odontoma’s which should be ruled out before going on for orthodontic therapy. The purpose of this article is to present and discuss the case of a 9-year old child with the chief complaint of spacing between the maxillary right permanent central incisor and right permanent lateral incisor. Radioopaque calcified masses were seen in the radiograph and was diagnosed with compound odontome followed by the surgical removal of the calcified masses

Deconfinement Phase Transition in Bosonic BMN Model at General Coupling

We present our analysis of the deconfinement phase transition in the bosonic BMN matrix model. The model is investigated using a non-perturbative lattice framework. We used the Polyakov loop as the order parameter to monitor the phase transition, and the results were verified using the separatrix ratio. The calculations are performed using a large number of colors and a broad range of temperatures for all couplings. Our results indicate a first-order phase transition in this theory for all the coupling values that connect the perturbative and non-perturbative regimes of the theory

Effect of Short-Term Placebo-Controlled Consumption of Probiotic Yoghurt and Indian Curd on the Streptococcus mutans Level in Children Undergoing Fixed Interceptive Orthodontic Therapy

Objective:To examine the effect of short-term consumption of probiotic yoghurt, Indian curd, and ultra-heated yoghurt as placebo on the levels of salivary and plaque Streptococcus mutans (S. mutans) in children undergoing fixed interceptive orthodontic therapy.Methods:A placebo-controlled double-blind study was carried out in a total of 30 children (8-15 years). The S. mutans level in the plaque and saliva were taken at the baseline and 2 weeks after the initiation of fixed orthodontic treatment by Dentocult SM kits. An equal number of participants randomized in three groups were asked to ingest 200 g of yoghurt containing Lactobacillus acidophilus La-1 and La-2 (>1×109 cfu/mL) once daily, Indian curd, or ultra-heated control yoghurt without viable bacteria and were followed for the S. mutans level after 2 weeks.Results:A significant reduction in salivary S. mutans levels was recorded after probiotic yoghurt ingestion (p=0.001) in addition to a reduction in the plaque S. mutans, which was observed after Indian curd consumption (p=0.026).Conclusion:Our findings suggest that short-term daily consumption of probiotic yoghurt along with Indian curd may help to reduce the levels of S. mutans in the saliva and plaque in children undergoing interceptive fixed orthodontic therapy

Non-perturbative phase structure of the bosonic BMN matrix model

We study the bosonic part of the BMN matrix model for wide ranges of temperatures, values of the deformation parameter, and numbers of colors $16 \leq N \leq 48$. Using lattice computations, we analyze phase transitions in the model, observing a single first-order transition from a uniform to a gapped phase for all values of the deformation parameter. We study the functional form of the dependence of the critical temperature on the deformation parameter, to describe how our results smoothly interpolate between the limits of the bosonic BFSS model and the gauged Gaussian model

Rare variant contribution to human disease in 281,104 UK Biobank exomes.

Genome-wide association studies have uncovered thousands of common variants associated with human disease, but the contribution of rare variants to common disease remains relatively unexplored. The UK Biobank contains detailed phenotypic data linked to medical records for approximately 500,000 participants, offering an unprecedented opportunity to evaluate the effect of rare variation on a broad collection of traits1,2. Here we study the relationships between rare protein-coding variants and 17,361 binary and 1,419 quantitative phenotypes using exome sequencing data from 269,171 UK Biobank participants of European ancestry. Gene-based collapsing analyses revealed 1,703 statistically significant gene-phenotype associations for binary traits, with a median odds ratio of 12.4. Furthermore, 83% of these associations were undetectable via single-variant association tests, emphasizing the power of gene-based collapsing analysis in the setting of high allelic heterogeneity. Gene-phenotype associations were also significantly enriched for loss-of-function-mediated traits and approved drug targets. Finally, we performed ancestry-specific and pan-ancestry collapsing analyses using exome sequencing data from 11,933 UK Biobank participants of African, East Asian or South Asian ancestry. Our results highlight a significant contribution of rare variants to common disease. Summary statistics are publicly available through an interactive portal ( http://azphewas.com/ )

Oral subcutaneous midline leiomyomatous hamartoma presenting as congenital incisive papilla overgrowth in a toddler

Congenital soft-tissue tumors of oral cavity are mostly hyperplastic and benign in nature. This article presents an unusual case of congenital subcutaneous hamartoma of incisive papilla in a 2-year-old female child causing feeding and breathing difficulty. Total excisional biopsy was done under local anesthesia. Histopathology of tissue in reticulin-stained slide showed the presence of immature muscle fibers whereas Masson's trichrome stain revealed collagen fibers and smooth muscles confirming the diagnosis of oral midline subcutaneous smooth muscle (leiomyomatous) hamartoma of incisive papilla. It is important for dental professionals to be aware of this oral lesion present from birth mimicking overgrowth of incisive papilla, by its presentation, differential diagnosis, histopathology, and management

Plaque removal efficacy of Colgate 360 toothbrush: A clinical study

Aim: The aim of this clinical study was to confirm the plaque removal efficacy of the Colgate 360 Whole Mouth Clean Toothbrush. Study Design: This was a single-center, monadic, case-controlled study with the 7 days duration. Materials and Methods: A total of eighty participants (56 male and 24 female) aged between 18 and 45 years with a minimum of 20 permanent teeth (excluding the third molars) without any prosthetic crowns and an initial plaque score of minimum 1.5 as determined by Modified Quigley-Hein Plaque Index (1970) participated in the study. There were two dropouts during the study duration, one male and one female. The participants were instructed to brush for 1 min, after which plaque index was recorded again. They were then instructed to brush their teeth twice a day for 1 min with the assigned toothbrush (Colgate 360 Whole Mouth Clean Toothbrush) and a commercially available fluoride toothpaste for the next 7 days. On the 7 th day, all the participants were recalled for follow-up and plaque examination. The plaque index scores (pre- and post-brushing) were recorded, tabulated, and analyzed statistically. Results: The mean plaque indices reduced after brushing both on day 1 and day 7. There was also a reduction in mean plaque indices from day 1 to day 7. All these reductions were statistically significant (P < 0.001). The reduction in plaque scores was independent of the gender of the participants however female participants showed lower scores as compared to male participants (P < 0.001). Conclusion: The present study demonstrated a significant reduction in plaque scores with the use of Colgate 360 Whole Mouth Clean Soft Toothbrush throughout the study period. Continued use resulted in a further significant reduction in plaque scores irrespective of the gender of participants

Transmission of mutans streptococci in mother-child pairs

Background & objectives: Dental caries is an infectious, transmissible disease. Maternal transfer of mutans streptococci (MS) has been a subject of research. The aim of this study was to evaluate the transmission of MS from mother to children through genetic analysis. Methods: Thirty mother-child pairs were included and divided into three groups according to the age of the children. Saliva samples were collected and MS colonies from each mother-child pair were isolated. After inoculation and incubation, MS colonies were submitted to amplification technique by polymerase chain reaction (PCR) for identification and arbitrarily primed PCRs (AP-PCRs) to determine various MS genotypes. Results: From birth to six months of age, 30 per cent of children exhibited MS colonization, and by the age of 30 months, 100 per cent harboured the bacteria (P < 0.001). Factors associated with MS colonization were eruption of teeth (P < 0.001), feeding habits with mean colony count being significantly lower in breast-fed as compared to bottle-fed children (P < 0.001) and a significant association between mean MS count of child and mother′s practice of sharing spoon with child (P < 0.001). The AP-PCR fingerprinting profile analysis showed 17 MS groups (clusters) containing identical or highly related isolates in mother-child pairs with a high level of similarity (77.27 %). Interpretation & conclusions: The presence of matching MS genotypes suggested vertical transmission from mothers to children. Feeding habits, gum cleaning and number of erupted teeth in children had significant effect on MS colonization. There is a need to develop strategies to present MS colonization in children