Differential effect of denervation on free radical scavenging enzymes in slow and fast muscle of rat

To determine the effect of denervation on the free radical scavenging systems in relation to the mitochondrial oxidative metabolism in the slow twitch soleus and fast twitch extensor digitorum longus (EDL) muscles, the sciatic nerve of the rat was crushed in the mid-thigh region and the muscle tissue levels of 5 enzymes were studied 2 and 5 weeks following crush. Radioimmunoassays were utilized for the selective measurement of cuprozinc (cytosolic) and mangano (mitochondrial) superoxide dismutases. These data represent the first systematic report of free radical scavening systems in slow and fast muscles in response to denervation. Selective modification of cuprozinc and manganosuperoxide dismutases and differential regulation of GSH-peroxidase was demonstrated in slow and fast muscle

Prevalence Rates of Mental Disorders in Chilean Prisons

PMCID: PMC371883

The search for the origin of the Local Bubble redivivus

We present a new unbiased search and analysis of all B stars in the solar neighbourhood (within a volume of 400 pc diameter) using the Arivel data base to track down the remains of the OB associations, which hosted the supernovae responsible for the Local Bubble in the interstellar gas. We find after careful dereddening and by comparison with theoretical isochrones, that besides the Upper Scorpius the Upper Centaurus Lupus and Lower Centaurus Crux subgroups are the youngest stellar associations in the solar neighbourhood with ages of 20 to 30 Myr, in agreement with previous work. In search for the ``smoking gun'' of the origin of the Local Bubble, we have traced the paths of the associations back into the past and found that they entered the present bubble region 10 to 15 Myr ago. We argue that the Local Bubble began to form then and estimate that 14 to 20 supernovae have gone off since. It is shown that the implied energy input is sufficient to excavate a bubble of the presently observed size.Comment: 10 pages, 8 figures, accepted by Mon. Not. R. Astron. So

Signatures of star streams in the phase space distribution of nearby halo stars

We have analyzed the phase space distribution of a sample of about 900 non-kinematically selected low metallicity stars in the solar vicinity. The stars primarily represent the thick disk and halo populations of the Milky Way. We aim to identify overdensely populated regions in phase space, which we interpret as signatures of star streams passing close to the Sun. The search was conducted in a space constructed from the angular momenta and eccentricities of the stellar orbits. Besides recovering all well known star streams in the thick disk, we isolated four statistically significant phase space overdensities amongst halo stars. One of them is associated with a previously known halo star stream, but three of them are novel features, which we propose be also considered as genuine halo streams