Plug-and-Participate for Limited Devices in the Field of Industrial Automation

Ausgangspunkt und gleichzeitig Motivation dieser Arbeit ist die heutige Marktsituation: Starke Kundenbedürfnisse nach individuellen Gütern stehen oftmals eher auf Massenproduktion ausgerichteten Planungs- und Automatisierungssystemen gegenüber - die Befriedigung individueller Kundenbedürfnisse setzt aber Flexibilität und Anpassungsfähigkeit voraus. Ziel dieser Arbeit ist es daher, einen Beitrag zu leisten, der es Unternehmen ermöglichen soll, auf diese individuellen Bedürfnisse flexibel reagieren zu können. Hierbei kann es im Rahmen der Dissertation natürlich nicht um eine Revolutionierung der gesamten Automatisierungs- und Planungslandschaft gehen; vielmehr ist die Lösung, die der Autor der Arbeit präsentiert, ein integraler Bestandteil eines Automatisierungskonzeptes, das im Rahmen des PABADIS Projektes entwickelt wurde: Während PABADIS das gesamte Spektrum von Planung und Maschineninfrastruktur zum Inhalt hat, bezieht sich der Kern dieser Arbeit weitestgehend auf den letztgenannten Punkt - Maschineninfrastruktur. Ziel war es, generische Maschinenfunktionalität in einem Netzwerk anzubieten, durch das Fertigungsaufträge selbstständig navigieren. Als Lösung präsentiert diese Dissertation ein Plug-and-Participate basiertes Konzept, welches beliebige Automatisierungsfunktionen in einer spontanen Gemeinschaft bereitstellt. Basis ist ein generisches Interface, in dem die generellen Anforderungen solcher ad-hoc Infrastrukturen aggregiert sind. Die Implementierung dieses Interfaces in der PABADIS Referenzimplementierung sowie die Gegenüberstellung der Systemanforderungen und Systemvoraussetzungen zeigte, das klassische Plug-and-Participate Technologien wie Jini und UPnP aufgrund ihrer Anforderungen nicht geeignet sind - Automatisierungsgeräte stellen oftmals nur eingeschränkte Ressourcen bereit. Daher wurde als zweites Ergebnis neben dem Plug-and-Participate basierten Automatisierungskonzept eine Plug-and-Participate Technologie entwickelt - Pini - die den Gegebenheiten der Automatisierungswelt gerecht wird und schließlich eine Anwendung von PABADIS auf heutigen Automatisierungsanlagen erlaubt. Grundlegende Konzepte von Pini, die dies ermöglichen, sind die gesamte Grundarchitektur auf Basis eines verteilten Lookup Service, die Art und Weise der Dienstrepräsentation sowie die effiziente Nutzung der angebotenen Dienste. Mit Pini und darauf aufbauenden Konzepten wie PLAP ist es nun insbesondere möglich, Automatisierungssysteme wie PABADIS auf heutigen Anlagen zu realisieren. Das wiederum ist ein Schritt in Richtung Kundenorientierung - solche Systeme sind mit Hinblick auf Flexibilität und Anpassungsfähigkeit gestaltet worden, um Kundenbedürfnissen effizient gerecht zu werden

Drone Maneuverability Around Built and Natural Structures: Phase I, Fabrication and Testing of Mock Environments

Undergraduate Applie

Psychosocial interventions for patients with chronic disease

Treatment of patients with chronic diseases will be one of the main challenges of medicine in the future. This paper presents an overview of different origins, mechanism, and symptoms necessary for understanding new and different interventions that include a psychosomatic view

Exploring Heterogeneous Phenotypes in Response to Stress

This work combines traditional microbiology with bioinformatic and synthetic biology approaches to study antibiotic tolerance. Antibiotic tolerance is a widespread phenomenon that facilitates antibiotic resistance and decreases the effectiveness of antibiotic treatment. Tolerance is distinct from antibiotic resistance, because tolerance is short term survival and typically results from phenotypic variations rather than genetic variation. The molecular mechanisms underlying tolerance are varied and debated in the literature. I have explored two intracellular processes related to tolerance, toxin-antitoxin (TA) systems (Chapter 2) and proteases (Chapter 4). Specifically, I focus on the ratio of antitoxin-to-toxin in type II TA systems, because type II TA systems must be regulated in such a way that antitoxins are more prevalent than their toxins. Our analysis of RNA-sequencing and ribosome profiling data demonstrates that most type II TA systems in E. coli are regulated at the translational level, while others rely on various combinations of transcriptional and post-transcriptional regulation. Before publishing this article, researchers often cited transcriptional regulation as the primary method of regulating TA systems. Studying antibiotic tolerance and other subpopulations necessitates the ability to study single-cell dynamics in the context of the whole population. To facilitate single-cell analysis, we have developed single-cell tracking software that leverages machine learning to identify cells. The software then tracks the cell based on this classification and returns data on cell size, location, division and fluorescence. The software provides the means of quantifying cell behavior before and after antibiotic treatment. One such system we would like to apply this software to is our work on proteolytic queueing and antibiotic tolerance. Proteases are responsible for protein degradation and, as such, regulate many cellular functions. To better identify the role proteases play in persistence, we used proteolytic queueing to interfere with proteolytic activity. We found that interfering with degradation at the protease ClpXP increases antibiotic tolerance ~80 and ~60 fold in an E. coli population treated with ampicillin and ciprofloxacin, respectively. I used stochastic modeling to support our results, and we have experimentally determined that altering the expression of the synthetic system affects the level of tolerance in the population. I am currently using next-generation sequencing to identify the systems being affected by the queue

Are the supporters of socialism the losers of capitalism?

Does a country’s democratisation have a long-lasting impact on former supporters or opponents of the bygone regime? Previous studies have been inconclusive. Max Deter and Martin Lange analyse how former supporters and opponents of the socialist German Democratic Republic (GDR) performed within the market-based democracy of reunified Germany. Protesters, who helped to overthrow the socialist regime, show higher life satisfaction and better labour market outcomes after reunification. Former members of the ruling socialist party and employees in state-supervised sectors became substantially less satisfied

Educating with the arts : how art education policy impacts educational outcomes.

The purpose of this paper is to explore the impact of art education policy on educational outcomes. While past literature focuses on how art in the classroom can raise individual test scores, this research takes a broader look at how policies impact outcomes on a state by state basis. The first part of the study uses OLS regression to estimate the effects of art policies on reading, math, and science standardized test scores. The results show that individual policies, as well as the total number of policies, have significant effects on the test scores. The second part compares the graduation and attendance rates, Academic Performance Index scores, and A-F Grades of Oklahoma schools that are OKA+ against those that are not. The results illustrate that while there was no significant difference between the two in A-F Grades, schools that prioritize art education do have higher graduation and attendance rates, as well as higher Academic Performance Index scores. Overall, this research provides evidence that enactment of art education policies state-wide can produce positive educational outcomes

Attracted to money and risk: the personality of finance professionals

Finance professionals have higher risk preferences and monetary motivation than the population as a whole. Max Deter and André van Hoorn analyse data on 465 bankers in Germany surveyed over 2,000 times between 2000 and 2017. They show that the preferences for risk and money are already present before they start to work in finance. The results indicate a business norm in the financial sector that attracts professionals who think in a riskier and more income-focused manner