82 research outputs found

    Barrier inhomogeneities of Al/p-In2Te3 thin film Schottky diodes

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    The current-voltage (I-V) and capacitance-voltage (C-V) characteristics of p-In2Te3/Al thin films Schottky diodes papered by Flash Evaporation technique were measured in the temperature range 303-335 K have been interpreted on the basis of the assumption of a Gaussian distribution of barrier heights (φbo) due to barrier height inhomogeneities that prevail at the interface. It has been found that the occurrence of Gaussian distribution of BHs is responsible for the decrease of the apparent BH (φbo) and increase of the ideality factor (η). The inhomogeneities are considered to have a Gaussian distribution with a mean barrier height of (φbm) and standard deviation (σs) at zero-bias. Furthermore, the activation energy value (φb) at T = 0 and Richardson constant (A**) value was obtained as 0.587 eV and 3.09 Acm– 2 K– 1 by means of usual Richardson plots. Hence, it has been concluded that the temperature dependence of the I-V characteristics of p-In2Te3/Al Schottky Diodes can be successfully explained on the basis of TE mechanism with a Gaussian distribution of the BHs. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/2790

    Antipseudomonal property of honey and aminoglycosides

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    Pseudomonas aeruginosa has an ability to rapidly develop resistance to most antimicrobial compounds, and to check this ability. The isolates were collected from different pathological human sources and tested for their sensitivity to aminoglycoside antibiotic and to honey, a natural product that is generating renewed interest for its therapeutic application using Kirby Bauer disc diffusion technique. Aminoglycoside antibiotic which is normally active against gram-negative bacteria was used alongside honey. The 29 isolates of P. aeruginosa showed 100%sensitivity to honey tested in their undiluted form. This was not the case with gentamicin (10?g) and amikacin (30 ?g), both of which varied in their antipseudomonal activity, like even 1:2 aqueous dilution of honey appreciably inhibited pseudomonal isolates than either of the two aminoglycoside antibiotic. Honey is therefore suggested as an effective natural product in overcoming the widespread antibiotic resistance of P. aeruginosa

    Mechanochemically Synthesized CIGS Nanocrystalline Powder for Solar Cell Application

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    Copper Indium Gallium Diselenide (CIGS) is a compound semiconductor material from the group of I-III-VI. The material is a solid solution of copper, indium and selenium (CIS) and copper, gallium and selenium with an empirical formula of CuIn(1 – x)GaxSe2, where 0 x 1. CIGS has an exceptionally high absorption coefficient of more than 105 cm – 1 for 1.5 eV. Solar cells prepared from absorber layers of CIGS materials have shown an efficiency higher than 20 %. CuIn(1 – x)GaxSe2 (x 0.3) nanocrystalline compound was mechanochemically synthesized by high-energy milling in a planetary ball mill. The phase identification and crystallite size of milled powders at different time intervals were carried out by X-ray diffraction (XRD). The XRD analysis indicates chalcopyrite structure and the crystallite size of about 10 nm of high-energy milled CIGS powder after two and half hours of milling. An attempt for preparing the thin film from CIGS nanocrystalline powder was carried out using the flash evaporation technique. Scanning electron microscopy (SEM) reveals uniform distribution of CIGS particles in thin film. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/3100

    Magnetron sputtered Al-ZnO Thin films for photovoltaic applications

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    The optimization process of the RF magnetron sputtered Al - doped ZnO (AZO) thin films was carried out by studying its structural, optical, electrical, and morphological properties at different RF power and different working pressures for its use as a front-contact for the copper indium diselenide (CIS) based thin film solar cell. The structural study suggests that the preferred orientation of grains along the ( 002) plane having a hexagonal structure of the grains. The optical and electrical properties suggest that the films show an average transmission of 85 % and a resistivity of the order of 10-4 Wcm. The morphology analysis suggests the formation of packed grains having a homogeneous surface. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/2210

    Evaluation of copper and haematological markers in atherosclerosis coronary heart disease

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    BackgroundCoronary heart disease [CHD] remains the major cause of morbidity and mortality in all developed as well as in developing countries. Leading cause of CHD is atherosclerosis, an inflammatory disease. Inflammation is closely related to thrombosis which begins with Platelets aggregation. Experimental Studies on animal model had been highlighted that copper may be associated with platelet aggregation but the data in human studies are lacking.AimsThis study was undertaken to evaluate role of haematological markers namely platelet count, clotting time, bleeding time and association of copper in pathogenesis of CHD.Methods The study was conducted was conducted in a single centre with retrospective atherosclerotic CHD cases and 100 as healthy controls. All 200 subjects were undergone through ECG and invasive coronary angiography. Haematological markers such as platelet counts, clotting time, bleeding time & Copper were measured in both groups by standard biochemical methods.Results Patients with the atherosclerotic CHD had decreased level of Platelet counts & Copper compared to healthy controls whereas there were no significant difference had been observed in CT & BT. Significant Positive correlation observed among the platelet count and copper levels in CHD cases. Post hoc analysis of platelet count and copper level in CHD cases and control subjects shows, significant positive correlation between the copper and platelet count levels in CHD cases, although on contrary there was non-significant negative correlation observed in copper and platelet counts levels among the control subjects.ConclusionCompared to control, low platelet count and copper levels in cases predict that platelets and copper may plays a crucial role in the development of atherosclerosis CHD and has correlation with each

    Mechanochemically Synthesized CIGS Nanocrystalline Powder for Solar Cell Application

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    Copper Indium Gallium Diselenide (CIGS) is a compound semiconductor material from the group of I-III-VI. The material is a solid solution of copper, indium and selenium (CIS) and copper, gallium and selenium with an empirical formula of CuIn(1 – x)GaxSe2, where 0 x 1. CIGS has an exceptionally high absorption coefficient of more than 105 cm – 1 for 1.5 eV. Solar cells prepared from absorber layers of CIGS materials have shown an efficiency higher than 20 %. CuIn(1 – x)GaxSe2 (x 0.3) nanocrystalline compound was mechanochemically synthesized by high-energy milling in a planetary ball mill. The phase identification and crystallite size of milled powders at different time intervals were carried out by X-ray diffraction (XRD). The XRD analysis indicates chalcopyrite structure and the crystallite size of about 10 nm of high-energy milled CIGS powder after two and half hours of milling. An attempt for preparing the thin film from CIGS nanocrystalline powder was carried out using the flash evaporation technique. Scanning electron microscopy (SEM) reveals uniform distribution of CIGS particles in thin film. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/3100

    The effect of deuteration on organic magnetoresistance

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    NOTICE: this is the author’s version of a work that was accepted for publication in Synthetic Metals. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in SYNTHETIC METALS, 161, 7-8, (2011) DOI 10.1016/j.synthmet.2010.11.04

    Efficacy of different fungicides against dry rot pathogen of potato caused by Fusarium sp. under in vitro condition

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    Potato crop is affected by numerous diseases in field, as well as in storage conditions, particularly in cold storage. Dry rot of potato is caused by Fusarium sp. Dry rot of seed tubers can reduce crop establishment by killing developing potato sprouts, and crop losses can be up to 25%, while more than 60% of tubers can be infected in storage. It is a rich source of energy, which supplement food source of a country. In this experiment, four systemic and four non-systemic fungicides were tested at different concentrations in vitro for their comparative efficacy against inhibition of the growth of Fusarium sp. through poisoned food technique. To manage these diseases effectively, different concentrations of fungicides were tested. Results revealed against Fusarium sp. that carbendazim and benomyl significantly inhibited the fungal growth even at its lower concentration (100 ppm) and proved statistically superior over the rest of the fungicides tested at different concentrations and among non-systemic fungicides, MEMC significantly inhibited the fungal growth even at its lower concentration (1000 ppm)

    A first-in-class, humanized antibody targeting alternatively spliced tissue factor: preclinical evaluation in an orthotopic model of pancreatic ductal adenocarcinoma

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    In 2021, pancreatic ductal adenocarcinoma (PDAC) is the 3(rd) leading cause of cancer deaths in the United States. This is largely due to a lack of symptoms and limited treatment options, which extend survival by only a few weeks. There is thus an urgent need to develop new therapies effective against PDAC. Previously, we have shown that the growth of PDAC cells is suppressed when they are co-implanted with RabMab1, a rabbit monoclonal antibody specific for human alternatively spliced tissue factor (asTF). Here, we report on humanization of RabMab1, evaluation of its binding characteristics, and assessment of its in vivo properties. hRabMab1 binds asTF with a K-D in the picomolar range; suppresses the migration of high-grade Pt45.P1 cells in Boyden chamber assays; has a long half-life in circulation (similar to 5 weeks); and significantly slows the growth of pre-formed orthotopic Pt45.P1 tumors in athymic nude mice when administered intravenously. Immunohistochemical analysis of tumor tissue demonstrates the suppression of i) PDAC cell proliferation, ii) macrophage infiltration, and iii) neovascularization, whereas RNAseq analysis of tumor tissue reveals the suppression of pathways that promote cell division and focal adhesion. This is the first proof-of-concept study whereby a novel biologic targeting asTF has been investigated as a systemically administered single agent, with encouraging results. Given that hRabMab1 has a favorable PK profile and is able to suppress the growth of human PDAC cells in vivo, it comprises a promising candidate for further clinical development.Thrombosis and Hemostasi
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