Symmetric Teleparallel Gravity: Some exact solutions and spinor couplings

In this paper we elaborate on the symmetric teleparallel gravity (STPG) written in a non-Riemannian spacetime with nonzero nonmetricity, but zero torsion and zero curvature. Firstly we give a prescription for obtaining the nonmetricity from the metric in a peculiar gauge. Then we state that under a novel prescription of parallel transportation of a tangent vector in this non-Riemannian geometry the autoparallel curves coincides with those of the Riemannian spacetimes. Subsequently we represent the symmetric teleparallel theory of gravity by the most general quadratic and parity conserving lagrangian with lagrange multipliers for vanishing torsion and curvature. We show that our lagrangian is equivalent to the Einstein-Hilbert lagrangian for certain values of coupling coefficients. Thus we arrive at calculating the field equations via independent variations. Then we obtain in turn conformal, spherically symmetric static, cosmological and pp-wave solutions exactly. Finally we discuss a minimal coupling of a spin-1/2 field to STPG.Comment: Accepted for publication in the International Journal of Modern Physics

A life-threatening problem occurring in the canalis inguinalis in children: Incarcerated hernia

Amaç: Çocuklarda görülen en sık cerrahi hastalık kasık fıtıklarıdır ve %5-18 oranında boğulma riski taşır. Bu çalışmada bebek ve çocuklarda görülen boğulmuş kasık fıtığının klinik özellikleri incelendi. Hastalar ve Yöntemler: Ocak 1994-Haziran 2006 döneminde boğulmuş kasık fıtığı nedeniyle takip ve tedavi edilen 33 çocuk olgunun (30 erkek, 3 kız; ort. yaş 2; dağılım 20 gün-6 yaş) kayıtları geriye dönük olarak incelendi. Bulgular: Kasıkta şişlik (n=33), kusma (n=19) ve skrotumda krepitasyon (n=10) en sık görülen semptomlardı. Olgulardan 26'sında elle geri itme girişimi başarılı oldu ancak yedi olguda acil cerrahi girişim yapılması gerekti. Fıtık kesesinde en çok sıkışan organ ince bağırsaklardı (n=22). Olgulardan üçünde testis iskemisi, ikisinde ince bağırsak, birinde ise kalın bağırsak iskemisi gelişmişti. Boğulmuş kasık fıtığı nedeniyle iki hasta (%6.0) kaybedildi. Sonuç: Bölgemizde boğulmuş kasık fıtığı olgularının hastaneye getirilmesinin geciktirildiği düşüncesindeyiz. Çocuklarda kasık fıtığı görüldüğünde mümkün olan en kısa zamanda ameliyat edilmelidir. Böylece boğulmuş kasık fıtığının yol açtığı yaşamsal sorunlar ortadan kaldırılmış olacaktır.Objectives: Inguinal hernia is the most common surgical disorder in childhood and is associated with 5-18 % incarceration risk. The clinical features of incarcerated inguinal hernia in infants and children were assessed. Patients and Methods: The medical records of 33 pediatric cases (30 males, 3 females; mean age 2 years; range 20 days-6 years) treated and followed up in our hospital for incarcerated inguinal hernia in the period of January 1994 and June 2006 were retrospectivelye evaluated. Results: The most frequent symptoms were inguinal lump (n=33), vomiting (n=19) and crepitation of the scrotum (n=10). Manual reduction of hernia was successful in 26 cases and 7 of them underwent emergency hernia repair. Small bowel was the most frequent incarcerated organ (n=22). Testicular ischemia developed in 3 patients, partial small bowel ischemia in 2, and colon ischemia in one patient. Two patients (6%) died due to incarcerated inguinal hernia. Conclusion: We think that in our region, cases of incarcerated inguinal hernia are admitted to the hospital with delay. The children with inguinal hernia should be operated as soon as possible. Life-threatening complications of incarcerated inguinal hernia may thus be prevented

A novel approach for preventing esophageal stricture formation: olmesartan prevented apoptosis

Accidentally ingested corrosive substances can cause functional and structural damage to the esophageal tissue resulting in stricture formation. It has been reported that the administration of olmesartan (OLM) can have anti-inflammatory, antifibrotic and antiapoptotic effects on injured tissue. The aim of our study was to check if OLM could prevent formation of scars in the corrosive esophageal burn model. Fifty-one Wistar Albino rats were divided into six groups: Control, Sham, OLM, Sham + OLM, Burn, and Burn + OLM. Olmesartan (5 mg/kg) was given by gavage once per day for 21 consecutive days after injury. The morphology of the esophagus was assessed after Masson trichrome staining, and apoptosis was evaluated using the terminal deoxynucleotidyl transferased UTP nick end labeling (TUNEL) method. The serum nucleosomes (as an indicator of apoptosis), serum p53 protein, and esophageal tissue p53 protein levels of each group were measured by immunoassays. Muscularis mucosa damage, submucosal collagen deposition, and tunica muscularis injury in the Burn + OLM group decreased significantly compared with the Burn group (p < 0.05). Similarly, the number of apoptotic cells in the Burn + OLM group decreased compared with the Burn group (p < 0.05). Serum levels of nucleosomes and p53 and tissue of p53 protein did not differ between the groups. Exogenously administered OLM can effectively prevent the occurrence of esophageal strictures caused by corrosive esophageal burns. (Folia Histochemica et Cytobiologica 2014, Vol. 52, No. 1, 29–35

Hydrogen sulfide:a novel mechanism for the vascular protection by resveratrol under oxidative stress in mouse aorta

Reactive oxygen species (ROS) decreases bioavailability of nitric oxide (NO) and impairs NO-dependent relaxations. Like NO, hydrogen sulfide (H2S) is an antioxidant and vasodilator; however, the effect of ROS on H2S-induced relaxations is unknown. Here we investigated whether ROS altered the effect of H2S on vascular tone in mouse aorta and determined whether resveratrol (RVT) protects it via H2S. Pyrogallol induced ROS formation. It also decreased H2S formation and relaxation induced by l-cysteine and in mouse aorta. Pyrogallol did not alter sodium hydrogensulfide (NaHS)-induced relaxation suggesting that the pyrogallol effect on l-cysteine relaxations was due to endogenous H2S formation. RVT inhibited ROS formation, enhanced l-cysteine-induced relaxations and increased H2S level in aortas exposed to pyrogallol suggesting that RVT protects against "H2S-dysfunctions" by inducing H2S formation. Indeed, H2S synthesis inhibitor AOAA inhibited the protective effects of RVT. RVT had no effect on Ach-induced relaxation that is NO dependent and the stimulatory effect of RVT on H2S-dependent relaxation was also independent of NO. These results demonstrate that oxidative stress impairs endogenous H2S-induced relaxations and RVT offers protection by inducing H2S suggesting that targeting endogenous H2S pathway may prevent vascular dysfunctions associated by oxidative stress

The evaluation of serum osteoprotegerin and omentin levels in women with polycystic ovarian syndrome

Bu çalışma Pamukkale Üniversitesi Bilimsel Araştırma Projeleri Koordinasyon Birimi’nin 14.11.2011 tarih ve 2011TPF043 proje nolu kararı ile desteklenmiştir.Literatürde Polikistik Over Sendrom'lu (PKOS) hastalarda Osteoprotegerin (OPG) ve Omentin düzeylerinin azaldığını bildiren çalışmalar vardır. Bu çalışmamızda hiperandrojenizm, bozulmuş glukoz metabolizması ve endotel hasarı ile karakterize bir bozukluk olan PKOS'ta OPG, Omentin ve insülin direnci arasındaki ilişkiyi ve Malondialdehit (MDA) düzeylerini incelemeyi amaçladık. Reprodüktif çağdaki 31 PKOS hastası ve 33 kontrol olgusunun demografik verileri, antropometrik ölçümleri, hormonal ve metabolik profilleri, serum Omentin, OPG ve MDA düzeyleri değerlendirildi. Çalışmamızda MDA düzeylerinin vücut kitle indeksi (VKİ) ve yaş ile anlamlı olarak ilişkili olduğunu saptadık. Fakat önceki literatür bilgilerinin aksine PKOS'lu hastaların MDA düzeyleri istatistiksel olarak anlamlı olmasa da kontrollere göre daha düşük saptandı. PKOS'lu hastaların OPG ve Omentin düzeyleri kontrollere göre düşük düzeyde saptandı, ancak bu ilişki de istatistiksel olarak anlamlı değildi. Bizim çalışmamızda genel literatür bilgisinden farklı olarak serum oksidatif stres parametreleri, omentin ve osteoprotegerin seviyeleri obez olmayan PKOS'lu kadınlarda anlamlı bir değişim göstermemiştir. Ayrıca omentin ve osteoprotegerin düzeylerinin artmış insülin direnci ve hiperandrojenizm bulguları ile bir ilişkisi de saptanamamıştır. Hasta sayısının nisbeten az olmasının ve olguların VKİ açısından eşleştirilememesinin bu sonuçlar üzerinde bir etkisinin olabileceğini düşünmekteyiz. Bu konuyu aydınlatmak için uzun süreli, randomize, kontrollü klinik çalışmalara ihtiyaç vardır.There is plenty of evidence that Osteoprotegerin (OPG) and Omentin levels are decreased in Polycystic Ovary Syndrome (PCOS). Our aim was to investigate the relationships with OPG, Omentin, insulin resistance, and Malondialdehyde (MDA) concentrations in PCOS, a disorder characterized by hyperandrogenism, impaired glucose control, and endothelial injury. Demographic datas, anthropometric measurements, hormonal and metabolic profiles, serum Omentin, OPG, and MDA levels were assessed in 31 PCOS patients and 33 controls of reproductive age. In our study there were statistically significant relationship between MDA levels and BMI and age. By contrast with previous literature knowledge, MDA levels of PCOS patients were lower than control group. But there was no statistical significance. OPG and Omentin levels were lower in PCOS group but there were no statistical significant findings too. Differently from general literature knowledge, in our study there were no significantly differences in the oxidative stress parameters, omentin and OPG levels of non-obese PCOS patients. Besides there were no relationships between Omentin, OPG levels and increased insulin resistance, hyperandrogenism. These conclusions can be attributed to the relatively small number of cases and BMI-mismatching. Randomized controlled trials or new high quality observational studies are needed to clarify the issue

20092023 dataset.sav

Both laparoscopic pectopexy (LPP) and vaginal sacrospinous fixation (VSSF) provide significant improvement of all symptoms in patients with pelvic organ prolapse (POP). LPP is a safe and easy-to-learn minimally invasive surgical technique for POP reconstruction.</p

Penetrating cardiac injury in blunt trauma: a case report

Künt toraks travmasına bağlı olarak nadiren kardiyak yaralanmalar görülebilmektedir. Kardiyak yaralanma genellikle hayatı tehdit eden durum yaratır, acil cerrahi müdahele geretirir ve bu hastaların perioperetif dönemde dikkatli takip edilmesi gerekir. Klinik tablo, yaralanma şekli, hastaneye ulaşana dek geçen süre, kanama miktarı, kardiyak tamponad varlığı veya ilave yaralanmalar gibi değişik faktörlere bağlıdır. Bu yazıda, künt toraks travmasına bağlı olarak penetran kardiyak yaralanma tespit edilen bir olgu sunuldu. Acil serviste araç içi trafik kazası nedeniyle değerlendirilen 61 yaşındaki erkek olgunun akciğer grafisinde pulmoner kontüzyon, kot kırığı ve kardiyak tamponad saptandı. Acilen ameliyata alınan hastada sağ atriyum yaralanması gözlendi. Kardiyak yaralanma primer dikiş tekniği ile onarıldı. Sonuç olarak, künt toraks travmalı hastalarda kardiyak yaralanma ihtimali yüksektir. Bu hastalarda dikkatli fiziksel inceleme, erken tanı ve tedavi gereklidir.Cardiac injuries may rarely be observed due to blunt thoracic traumas. Cardiac injury often creates a life-threatening condition requiring urgent surgical intervention, and follow-up of these patients should be carefully carried out in the perioperative period. These injuries depend on various factors including clinical presentation, type of injury, the time that passes until the patient reaches the hospital, bleeding, cardiac tamponade, or additional injuries. This article aimed to report a case who suffered penetrating cardiac injury in blunt thoracic trauma. Evaluated in the emergency department due to a motor vehicle accident, the 61-year-old male patient's chest x-ray revealed pulmonary contusion, rib fractures and cardiac tamponade. The patient was operated emergently. Right atrial injury was observed in the operation. The cardiac injury was repaired with primary suture technique. Cardiac injury in patients with blunt thoracic trauma is likely to be observed. In these patients, careful physical examination, early diagnosis, and treatment are very important

Evde hiperhidroz tedavisi için geliştirilmiş bir iyontoforez cihazı

Palmoplantar hyperhidrosis (PPH) reduces the quality of life. Tap water iontophoresis is one of the most suggested methods in the treatment of PPH. One session of 20 minutes daily for 20 days are usually adequate, lontophoretic home-therapy of PPH without a visiting to a medical center may increase patients compliance to the therapy and save time. In this study, a microprocessor controlled fully automatic tap water iontophoresis device was designed and developed for home-therapy. The device is activated by introducing the hands and feet into the water, gradually increases its current to a desired level, runs throughout a certain time, and then automatically stops after gradually decreasing its current to zero. The device works with 220 VAC and has extra features to protect the patient from electric shocks.Eleven patients who had no benefit from other treatment methods used this iontophoresis device at their home. Patient satisfaction, maximum current levels, side effects, and the affectivity of treatment were evaluated after 20 days. All patients reported that they had not experienced any difficulty or any electric shock during the period of treatment. Ten (%91) patients had normo- or hypohidrosis after treatment. Nine (% 82) patients reported that they wish to maintain the treatment with the same iontophoresis device.Palmoplantar hiperhidroz (PPH) hastanın yaşam kalitesini azaltan bir hastalıktır. Çeşme suyu iyontoforezi, PPH tedavisinde mutlaka önerilen yöntemlerin başında gelmektedir. Günde 20 dakika ve toplam 20 seans olarak uygulanması çoğunlukla yeterlidir. Hastaların çeşme suyu iyontoforezini, her seansta bir tıp merkezine gitmesine gerek kalmadan evlerinde tek başına yapabilmeleri tedaviye uyumu arttıracak ve zaman kazandıracaktır. Bu çalışmada, mikroişlemci kontrollü, tamamen otomatik olarak çalışan bir iyontoforez cihazı tasarlanmış ve geliştirilmiştir. Cihaz, hastanın el ve ayaklarının suya teması ile çalışmaya başlamakta, akım şiddetini önceden belirlenen şiddete kadar yavaş yavaş yükseltmekte, önceden belirlenen süre sonunda da akımı yavaş yavaş sıfıra düşürerek tedaviyi sonlandırmaktadır. Şehir cereyanı ile çalışan bu cihaza elektrik şoku ve olası arızalara karşı hastayı koruyan çeşitli özellikler de eklenmiştir. Geliştirilen cihaz diğer tedavilerden yarar görmeyen ve herhangi bir sistemik hastalığı bulunmayan on bir hastaya evlerinde kullanmak üzere verilmiştir. Yirmi seanslık tedaviden sonra tedavinin etkinliği, yan etkileri, uyguladıkları akım şiddetleri ile cihazdan ve uygulamadan dolayı memnuniyetleri değerlendirilmiştir. Hastaların tümü cihazın kullanımı sırasında zorluk çekmediklerini veya herhangi bir elektrik şoku yaşamadıklarını belirtmişlerdir. On (%91) hastada normo veya hipohidroz sağlanmıştır. Dokuz (%82) hasta, idame tedaviyi cihazla sürdürmek istediğini belirtmiştir. Evde kullanılmaküzere geliştirilen bu cihaz, otomatik çalışma özellikleri ile palmoplantar hiperhidrozun iyontoforez ile tedavisine hasta uyumunu kolaylaştırmaktadır

Solving the generalized rosenau-kdv equation by the meshless kernel-based method of lines

This current investigation consists of the numerical solutions of the Generalized Rosenau-KdV equation by using the meshless kernel-based method of lines, which is a truly meshless method. The governing equation is a nonlinear partial differential equation but the use of the method of lines leads to an ordinary differential equation. Thus, the partial differential equation is replaced by the ordinary differential equation. The numerical efficiency of the used technique is tested by different numerical examples. Numerical values of error norms and physical invariants are compared with known values in the literature. Moreover, Multiquadric, Gaussian, and Wendland’s compactly supported functions are used in computations. It is seen that the used truly meshless method in computations is very effective with high accuracy and reliability